Macrophage infiltration promotes invasiveness of breast cancer cells via activating long non-coding RNA UCA1

International Journal of Clinical and Experimental Pathology

Volumn 8, Issue 8, 2015, Pages 9052-9061

  Chen, Shuzheng ^a   Shao, Chuxiao ^a   Xu, Min ^a   Ji, Jiansong ^a   Xie, Yanru ^a   Lei, Yongliang ^b   Wang, Xiaoguang ^b  

^a LISHUI CENTRAL HOSPITAL   (China)

^b Lishui Center for Disease Prevention and Control   (China)

Author keywords

Breast cancer; Macrophage; UCA1

Indexed keywords

CONDITIONED MEDIUM; LONG UNTRANSLATED RNA; SMALL INTERFERING RNA; UCA1 RNA, HUMAN;

APOPTOSIS; BREAST TUMOR; CELL PROLIFERATION; CONDITIONED MEDIUM; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MACROPHAGE; METABOLISM; PATHOLOGY; TUMOR CELL LINE; TUMOR INVASION;

APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CULTURE MEDIA, CONDITIONED; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MACROPHAGES; NEOPLASM INVASIVENESS; RNA, LONG NONCODING; RNA, SMALL INTERFERING;

EID: 85012977850     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Takanami I, Takeuchi K and Kodaira S. Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: association with angiogenesis and poor prognosis. Oncology 1999; 57: 138-142.
2. Leek RD, Lewis CE, Whitehouse R, Greenall M, Clarke J and Harris AL. Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res 1996; 56: 4625-4629.
3. Leonardi GC, Candido S, Cervello M, Nicolosi D, Raiti F, Travali S, Spandidos DA and Libra M. The tumor microenvironment in hepatocellular carcinoma (review). Int J Oncol 2012; 40: 1733-1747.
4. Yang JD, Nakamura I and Roberts LR. The tumor microenvironment in hepatocellular carcinoma: current status and therapeutic targets. Semin Cancer Biol 2011; 21: 35-43.
5. Deng WJ, Nie S, Dai J, Wu JR and Zeng R. Proteome, phosphoproteome, and hydroxyproteome of liver mitochondria in diabetic rats at early pathogenic stages. Mol Cell Proteomics 2010; 9: 100-116.
6. Gordon S and Taylor PR. Monocyte and macrophage heterogeneity. Nat Rev Immunol 2005; 5: 953-964.
7. Hao NB, Lu MH, Fan YH, Cao YL, Zhang ZR and Yang SM. Macrophages in tumor microenvironments and the progression of tumors. Clin Dev Immunol 2012; 2012: 948098.
8. Yang C, Li X, Wang Y, Zhao L and Chen W. Long non-coding RNA UCA1 regulated cell cycle distribution via CREB through PI3-K dependent pathway in bladder carcinoma cells. Gene 2012; 496: 8-16.
9. Takahashi K, Yan IK, Kogure T, Haga H and Patel T. Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer. FEBS Open Bio 2014; 4: 458-467.
10. Yin S, Yang J, Lin B, Deng W, Zhang Y, Yi X, Shi Y, Tao Y, Cai J, Wu CI, Zhao G, Hurst LD, Zhang J, Hu L and Kong X. Exome sequencing identifies frequent mutation of MLL2 in non-small cell lung carcinoma from Chinese patients. Sci Rep 2014; 4: 6036.
11. Ponting CP, Oliver PL and Reik W. Evolution and functions of long noncoding RNAs. Cell 2009; 136: 629-641.
12. Mattick JS. The genetic signatures of noncoding RNAs. PLoS Genet 2009; 5: e1000459.
13. Taft RJ, Pang KC, Mercer TR, Dinger M and Mattick JS. Non-coding RNAs: regulators of disease. J Pathol 2010; 220: 126-139.
14. Perez DS, Hoage TR, Pritchett JR, Ducharme-Smith AL, Halling ML, Ganapathiraju SC, Streng PS and Smith DI. Long, abundantly expressed non-coding transcripts are altered in cancer. Hum Mol Genet 2008; 17: 642-655.
15. Yin S, Deng W, Hu L and Kong X. The impact of nucleosome positioning on the organization of replication origins in eukaryotes. Biochem Biophys Res Commun 2009; 385: 363-368.
16. Li JY, Ma X and Zhang CB. Overexpression of long non-coding RNA UCA1 predicts a poor prognosis in patients with esophageal squamous cell carcinoma. Int J Clin Exp Pathol 2014; 7: 7938-7944.
17. Tsang WP, Wong TW, Cheung AH, Co CN and Kwok TT. Induction of drug resistance and transformation in human cancer cells by the noncoding RNA CUDR. RNA 2007; 13: 890-898.
18. Wang Y, Chen W, Yang C, Wu W, Wu S, Qin X and Li X. Long non-coding RNA UCA1a(CUDR) promotes proliferation and tumorigenesis of bladder cancer. Int J Oncol 2012; 41: 276-284.
19. Fan Y, Shen B, Tan M, Mu X, Qin Y, Zhang F and Liu Y. Long non-coding RNA UCA1 increases chemoresistance of bladder cancer cells by regulating Wnt signaling. FEBS J 2014; 281: 1750-1758.
20. Han Y, Yang YN, Yuan HH, Zhang TT, Sui H, Wei XL, Liu L, Huang P, Zhang WJ and Bai YX. UCA1, a long non-coding RNA up-regulated in colorectal cancer influences cell proliferation, apoptosis and cell cycle distribution. Pathology 2014; 46: 396-401.
21. Wang F, Ying HQ, He BS, Pan YQ, Deng QW, Sun HL, Chen J, Liu X and Wang SK. Upregulated lncRNA-UCA1 contributes to progression of hepatocellular carcinoma through inhibition of miR-216b and activation of FGFR1/ERK signaling pathway. Oncotarget 2015; 6: 7899-917.
22. Lopez MF, Krastins B, Sarracino DA, Byram G, Vogelsang MS, Prakash A, Peterman S, Ahmad S, Vadali G, Deng W, Inglessis I, Wickham T, Feeney K, Dec GW, Palacios I, Buonanno FS, Lo EH and Ning M. Proteomic signatures of serum albumin-bound proteins from stroke patients with and without endovascular closure of PFO are significantly different and suggest a novel mechanism for cholesterol efflux. Clin Proteomics 2015; 12: 2.
23. Huang J, Zhou N, Watabe K, Lu Z, Wu F, Xu M and Mo YY. Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1). Cell Death Dis 2014; 5: e1008.
24. Wang Y, Xu Z, Jiang J, Xu C, Kang J, Xiao L, Wu M, Xiong J, Guo X and Liu H. Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal. Dev Cell 2013; 25: 69-80.
25. Askarian-Amiri ME, Seyfoddin V, Smart CE, Wang J, Kim JE, Hansji H, Baguley BC, Finlay GJ and Leung EY. Emerging role of long non-coding RNA SOX2OT in SOX2 regulation in breast cancer. PLoS One 2014; 9: e102140.
26. Lei H, Zhai B, Yin S, Gygi S and Reed R. Evidence that a consensus element found in naturally intronless mRNAs promotes mRNA export. Nucleic Acids Res 2013; 41: 2517-2525.
27. Yin S, Wang P, Deng W, Zheng H, Hu L, Hurst LD and Kong X. Dosage compensation on the active X chromosome minimizes transcriptional noise of X-linked genes in mammals. Genome Biol 2009; 10: R74.
28. Yin S, Deng W, Zheng H, Zhang Z, Hu L and Kong X. Evidence that the nonsense-mediated mRNA decay pathway participates in X chromosome dosage compensation in mammals. Biochem Biophys Res Commun 2009; 383: 378-382.
29. Wang P, Yin S, Zhang Z, Xin D, Hu L, Kong X and Hurst LD. Evidence for common short natural trans sense-antisense pairing between transcripts from protein coding genes. Genome Biol 2008; 9: R169.
30. Chan CT, Deng W, Li F, DeMott MS, Babu IR, Begley TJ and Dedon PC. Highly Predictive Reprogramming of tRNA Modifications Is Linked to Selective Expression of Codon-Biased Genes. Chem Res Toxicol 2015; 28: 978-988.
31. Chan CT, Pang YL, Deng W, Babu IR, Dyavaiah M, Begley TJ and Dedon PC. Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins. Nat Commun 2012; 3: 937.
32. Biswas SK and Mantovani A. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol 2010; 11: 889-896.
33. Ohno S, Inagawa H, Dhar DK, Fujii T, Ueda S, Tachibana M, Suzuki N, Inoue M, Soma G and Nagasue N. The degree of macrophage infiltration into the cancer cell nest is a significant predictor of survival in gastric cancer patients. Anticancer Res 2003; 23: 5015-5022.
34. Medrek C, Ponten F, Jirstrom K and Leandersson K. The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients. BMC Cancer 2012; 12: 306.