메뉴 건너뛰기




Volumn 9, Issue 7, 2014, Pages

Emerging role of long non-coding RNA SOX2OT in SOX2 regulation in breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; LONG UNTRANSLATED RNA; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTION FACTOR SOX;

EID: 84903974262     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102140     Document Type: Article
Times cited : (119)

References (59)
  • 1
    • 0034669139 scopus 로고    scopus 로고
    • Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators
    • Bowles J, Schepers G, Koopman P (2000) Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators. Dev Biol 227: 239-255.
    • (2000) Dev Biol , vol.227 , pp. 239-255
    • Bowles, J.1    Schepers, G.2    Koopman, P.3
  • 2
    • 0036668285 scopus 로고    scopus 로고
    • Matching SOX: Partner proteins and co-factors of the SOX family of transcriptional regulators
    • DOI 10.1016/S0959-437X(02)00323-4
    • Wilson M, Koopman P (2002) Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators. Curr Opinion Genet Dev 12: 441-446. (Pubitemid 34722924)
    • (2002) Current Opinion in Genetics and Development , vol.12 , Issue.4 , pp. 441-446
    • Wilson, M.1    Koopman, P.2
  • 3
    • 0034175998 scopus 로고    scopus 로고
    • Pairing SOX off: With partners in the regulation of embryonic development
    • DOI 10.1016/S0168-9525(99)01955-1, PII S0168952599019551
    • Kamachi Y, Uchikawa M, Kondoh H (2000) Pairing SOX off: with partners in the regulation of embryonic development. Trends Genet 16: 182-187. (Pubitemid 30169154)
    • (2000) Trends in Genetics , vol.16 , Issue.4 , pp. 182-187
    • Kamachi, Y.1    Uchikawa, M.2    Kondoh, H.3
  • 4
    • 33747195353 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
    • DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
    • Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663-676. (Pubitemid 44233629)
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 5
    • 38049028459 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
    • Nakagawa M, Koyanagi M, Tanabe K, Takahashi K, Ichisaka T, et al. (2008) Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 26: 101-106.
    • (2008) Nat Biotechnol , vol.26 , pp. 101-106
    • Nakagawa, M.1    Koyanagi, M.2    Tanabe, K.3    Takahashi, K.4    Ichisaka, T.5
  • 6
    • 55749104227 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
    • Huangfu D, Osafune K, Maehr R, Guo W, Eijkelenboom A, et al. (2008) Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nat Biotechnol 26: 1269-1275.
    • (2008) Nat Biotechnol , vol.26 , pp. 1269-1275
    • Huangfu, D.1    Osafune, K.2    Maehr, R.3    Guo, W.4    Eijkelenboom, A.5
  • 7
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline-competent induced pluripotent stem cells
    • DOI 10.1038/nature05934, PII NATURE05934
    • Okita K, Ichisaka T, Yamanaka S (2007) Generation of germline-competent induced pluripotent stem cells. Nature 448: 313-317. (Pubitemid 47080336)
    • (2007) Nature , vol.448 , Issue.7151 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 8
    • 80055106066 scopus 로고    scopus 로고
    • Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas
    • Alonso M, Diez-Valle R, Manterola L, Rubio A, Liu D, et al. (2011) Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas. PLoS One 6: e26740.
    • (2011) PLoS One , vol.6
    • Alonso, M.1    Diez-Valle, R.2    Manterola, L.3    Rubio, A.4    Liu, D.5
  • 9
    • 84861343721 scopus 로고    scopus 로고
    • Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas
    • Basu-Roy U, Seo E, Ramanathapuram L, Rapp T, Perry J, et al. (2012) Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas. Oncogene 31: 2270-2282.
    • (2012) Oncogene , vol.31 , pp. 2270-2282
    • Basu-Roy, U.1    Seo, E.2    Ramanathapuram, L.3    Rapp, T.4    Perry, J.5
  • 10
    • 49649106548 scopus 로고    scopus 로고
    • The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer
    • Chen Y, Shi L, Zhang L, Li R, Liang J, et al. (2008) The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer. J Biol Chem 283: 17969-17978.
    • (2008) J Biol Chem , vol.283 , pp. 17969-17978
    • Chen, Y.1    Shi, L.2    Zhang, L.3    Li, R.4    Liang, J.5
  • 11
    • 84865504366 scopus 로고    scopus 로고
    • Elevating SOX2 levels deleteriously affects the growth of medulloblastoma and glioblastoma cells
    • Cox J, Wilder P, Desler M, Rizzino A (2012) Elevating SOX2 levels deleteriously affects the growth of medulloblastoma and glioblastoma cells. PLoS One 7: e44087.
    • (2012) PLoS One , vol.7
    • Cox, J.1    Wilder, P.2    Desler, M.3    Rizzino, A.4
  • 14
    • 79251564420 scopus 로고    scopus 로고
    • Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma
    • Lengerke C, Fehm T, Kurth R, Neubauer H, Scheble V, et al. (2011) Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma. BMC Cancer 11: 42.
    • (2011) BMC Cancer , vol.11 , pp. 42
    • Lengerke, C.1    Fehm, T.2    Kurth, R.3    Neubauer, H.4    Scheble, V.5
  • 15
    • 4043163494 scopus 로고    scopus 로고
    • Expression of the SRY-related HMG box protein SOX2 in human gastric carcinoma
    • Li X, Eishi Y, Bai YQ, Sakai H, Akiyama Y, et al. (2004) Expression of the SRY-related HMG box protein SOX2 in human gastric carcinoma. Int J Oncol 24: 257-263.
    • (2004) Int J Oncol , vol.24 , pp. 257-263
    • Li, X.1    Eishi, Y.2    Bai, Y.Q.3    Sakai, H.4    Akiyama, Y.5
  • 16
    • 33646051846 scopus 로고    scopus 로고
    • Histopathologic evaluation of stepwise progression of pancreatic carcinoma with immunohistochemical analysis of gastric epithelial transcription factor SOX2: Comparison of expression patterns between invasive components and cancerous or nonneoplastic intraductal components
    • Sanada Y, Yoshida K, Ohara M, Oeda M, Konishi K, et al. (2006) Histopathologic evaluation of stepwise progression of pancreatic carcinoma with immunohistochemical analysis of gastric epithelial transcription factor SOX2: comparison of expression patterns between invasive components and cancerous or nonneoplastic intraductal components. Pancreas 32: 164-170.
    • (2006) Pancreas , vol.32 , pp. 164-170
    • Sanada, Y.1    Yoshida, K.2    Ohara, M.3    Oeda, M.4    Konishi, K.5
  • 17
    • 0033767571 scopus 로고    scopus 로고
    • Novel amplification unit at chromosome 3q25-q27 in human prostate cancer
    • Sattler H, Lensch R, Rohde V, Zimmer E, Meese E, et al. (2000) Novel amplification unit at chromosome 3q25-q27 in human prostate cancer. Prostate 45: 207-215.
    • (2000) Prostate , vol.45 , pp. 207-215
    • Sattler, H.1    Lensch, R.2    Rohde, V.3    Zimmer, E.4    Meese, E.5
  • 18
    • 83255187897 scopus 로고    scopus 로고
    • Distinct functions of Sox2 control self-renewal and differentiation in the osteoblast lineage
    • Seo E, Basu-Roy U, Zavadil J, Basilico C, Mansukhani A (2011) Distinct functions of Sox2 control self-renewal and differentiation in the osteoblast lineage. Mol Cell Biol 31: 4593-4608.
    • (2011) Mol Cell Biol , vol.31 , pp. 4593-4608
    • Seo, E.1    Basu-Roy, U.2    Zavadil, J.3    Basilico, C.4    Mansukhani, A.5
  • 20
    • 84865325894 scopus 로고    scopus 로고
    • Identification of two novel phenotypically distinct breast cancer cell subsets based on Sox2 transcription activity
    • Wu F, Zhang J, Wang P, Ye X, Jung K, et al. (2012) Identification of two novel phenotypically distinct breast cancer cell subsets based on Sox2 transcription activity. Cell Signal 24: 1989-1998.
    • (2012) Cell Signal , vol.24 , pp. 1989-1998
    • Wu, F.1    Zhang, J.2    Wang, P.3    Ye, X.4    Jung, K.5
  • 21
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • DOI 10.1038/ng.127, PII NG127
    • Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, et al. (2008) An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nature Genet 40: 499-507. (Pubitemid 351601215)
    • (2008) Nature Genetics , vol.40 , Issue.5 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3    Ge, R.4    Bell, G.W.5    Regev, A.6    Weinberg, R.A.7
  • 23
    • 83355163224 scopus 로고    scopus 로고
    • The enhancement of cancer stem cell properties of MCF-7 cells in 3D collagen scaffolds for modeling of cancer and anti-cancer drugs
    • Chen L, Xiao Z, Meng Y, Zhao Y, Han J, et al. (2012) The enhancement of cancer stem cell properties of MCF-7 cells in 3D collagen scaffolds for modeling of cancer and anti-cancer drugs. Biomaterials 33: 1437-1444.
    • (2012) Biomaterials , vol.33 , pp. 1437-1444
    • Chen, L.1    Xiao, Z.2    Meng, Y.3    Zhao, Y.4    Han, J.5
  • 27
    • 9944266165 scopus 로고    scopus 로고
    • Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells
    • DOI 10.1101/gad.309404
    • Kondo T, Raff M (2004) Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells. Genes Dev 18: 2963-2972. (Pubitemid 39602314)
    • (2004) Genes and Development , vol.18 , Issue.23 , pp. 2963-2972
    • Kondo, T.1    Raff, M.2
  • 30
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander E, Linton L, Birren B, Nusbaum C, Zody M, et al. (2001) Initial sequencing and analysis of the human genome. Nature 409: 860-921.
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.1    Linton, L.2    Birren, B.3    Nusbaum, C.4    Zody, M.5
  • 32
    • 34249721400 scopus 로고    scopus 로고
    • Constructing the landscape of the mammalian transcriptome
    • Carninci P (2007) Constructing the landscape of the mammalian transcriptome. J Exp Biol 210: 1497-1506.
    • (2007) J Exp Biol , vol.210 , pp. 1497-1506
    • Carninci, P.1
  • 33
    • 60349120914 scopus 로고    scopus 로고
    • Long non-coding RNAs: Insights into functions
    • Mercer T, Dinger ME, Mattick JS. (2009) Long non-coding RNAs: Insights into functions. Nat Rev Genet 10: 155-159.
    • (2009) Nat Rev Genet , vol.10 , pp. 155-159
    • Mercer, T.1    Dinger, M.E.2    Mattick, J.S.3
  • 34
    • 29444457713 scopus 로고    scopus 로고
    • Rapid evolution of noncoding RNAs: Lack of conservation does not mean lack of function
    • DOI 10.1016/j.tig.2005.10.003, PII S0168952505003227
    • Pang K, Frith M, Mattick J (2006) Rapid evolution of noncoding RNAs: lack of conservation does not mean lack of function. Trends Genet 22: 1-5. (Pubitemid 43011990)
    • (2006) Trends in Genetics , vol.22 , Issue.1 , pp. 1-5
    • Pang, K.C.1    Frith, M.C.2    Mattick, J.S.3
  • 36
    • 70350118664 scopus 로고    scopus 로고
    • Complex architecture and regulated expression of the Sox2ot locus during vertebrate development
    • Amaral P, Neyt C, Wilkins SJ, Askarian-Amiri ME, Sunkin SM, et al. (2009) Complex architecture and regulated expression of the Sox2ot locus during vertebrate development. RNA 15: 2013-2027.
    • (2009) RNA , vol.15 , pp. 2013-2027
    • Amaral, P.1    Neyt, C.2    Wilkins, S.J.3    Askarian-Amiri, M.E.4    Sunkin, S.M.5
  • 37
    • 84891792702 scopus 로고    scopus 로고
    • Two Novel Splice Variants of SOX2OT, SOX2OT-S1, and SOX2OT-S2 are Coupregulated with SOX2 and OCT4 in Esophageal Squamous Cell Carcinoma
    • Shahryari A, Rafiee M, Fouani Y, Oliae N, Samaei N, et al. (2014) Two Novel Splice Variants of SOX2OT, SOX2OT-S1, and SOX2OT-S2 are Coupregulated with SOX2 and OCT4 in Esophageal Squamous Cell Carcinoma. Stem Cells 32: 126-134.
    • (2014) Stem Cells , vol.32 , pp. 126-134
    • Shahryari, A.1    Rafiee, M.2    Fouani, Y.3    Oliae, N.4    Samaei, N.5
  • 38
    • 84878623584 scopus 로고    scopus 로고
    • In vitro analysis of breast cancer cell line tumourspheres and primary human breast epithelia mammospheres demonstrates inter- and intrasphere heterogeneity
    • Smart C, Morrison B, Saunus J, Vargas A, Keith P, et al. (2013) In vitro analysis of breast cancer cell line tumourspheres and primary human breast epithelia mammospheres demonstrates inter- and intrasphere heterogeneity. PLoS One 8: e64388.
    • (2013) PLoS One , vol.8
    • Smart, C.1    Morrison, B.2    Saunus, J.3    Vargas, A.4    Keith, P.5
  • 39
    • 77953717846 scopus 로고    scopus 로고
    • MCF-7 breast cancer cells selected for tamoxifen resistance acquire new phenotypes differing in DNA content, phospho-HER2 and PAX2 expression, and rapamycin sensitivity
    • Leung E, Kannan N, Krissansen G, Findlay M, Baguley B (2010) MCF-7 breast cancer cells selected for tamoxifen resistance acquire new phenotypes differing in DNA content, phospho-HER2 and PAX2 expression, and rapamycin sensitivity. Cancer Biol Ther 9: 717-724.
    • (2010) Cancer Biol Ther , vol.9 , pp. 717-724
    • Leung, E.1    Kannan, N.2    Krissansen, G.3    Findlay, M.4    Baguley, B.5
  • 40
    • 33644800080 scopus 로고    scopus 로고
    • Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivo detection of mammary tumors and multiple metastases in immune deficient mice
    • Jenkins D, Hornig Y, Oei Y, Dusich J, Purchio T (2005) Bioluminescent human breast cancer cell lines that permit rapid and sensitive in vivo detection of mammary tumors and multiple metastases in immune deficient mice. Breast Cancer Res 7: R444-454.
    • (2005) Breast Cancer Res , vol.7
    • Jenkins, D.1    Hornig, Y.2    Oei, Y.3    Dusich, J.4    Purchio, T.5
  • 41
    • 79955005458 scopus 로고    scopus 로고
    • SNORD-host RNA Znfx1-as is a regulator of mammary development and a potential marker for breast cancer
    • Askarian-Amiri ME, Crawford J, French JD, Smith MA, Smart CE, et al. (2011) SNORD-host RNA Znfx1-as is a regulator of mammary development and a potential marker for breast cancer. RNA 17: 878-891.
    • (2011) RNA , vol.17 , pp. 878-891
    • Askarian-Amiri, M.E.1    Crawford, J.2    French, J.D.3    Smith, M.A.4    Smart, C.E.5
  • 42
    • 79957818433 scopus 로고    scopus 로고
    • Comparison of the effects of the PI3K/mTOR inhibitors NVP-BEZ235 and GSK2126458 on tamoxifen-resistant breast cancer cells
    • Leung E, Kim J, Rewcastle G, Finlay G, Baguley B (2011) Comparison of the effects of the PI3K/mTOR inhibitors NVP-BEZ235 and GSK2126458 on tamoxifen-resistant breast cancer cells. Cancer Biol Ther 11: 938-946.
    • (2011) Cancer Biol Ther , vol.11 , pp. 938-946
    • Leung, E.1    Kim, J.2    Rewcastle, G.3    Finlay, G.4    Baguley, B.5
  • 43
    • 34347230544 scopus 로고    scopus 로고
    • Sulforhodamine B colorimetric assay for cytotoxicity screening
    • Vichai V, Kirtikara K (2006) Sulforhodamine B colorimetric assay for cytotoxicity screening. Nat Protoc 1: 1112-1116.
    • (2006) Nat Protoc , vol.1 , pp. 1112-1116
    • Vichai, V.1    Kirtikara, K.2
  • 44
    • 84892747673 scopus 로고    scopus 로고
    • Identification of expressed and conserved human noncoding RNAs
    • Nielsen M, Tehler D, Vang S, Sudzina F, Hedegaard J, et al. (2014) Identification of expressed and conserved human noncoding RNAs. RNA 20: 236-251.
    • (2014) RNA , vol.20 , pp. 236-251
    • Nielsen, M.1    Tehler, D.2    Vang, S.3    Sudzina, F.4    Hedegaard, J.5
  • 47
    • 48949119473 scopus 로고    scopus 로고
    • Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy
    • Fillmore C, Kuperwasser C (2008) Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy. Breast Cancer Res 10: R25.
    • (2008) Breast Cancer Res , vol.10
    • Fillmore, C.1    Kuperwasser, C.2
  • 48
    • 55749106963 scopus 로고    scopus 로고
    • Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells
    • Grimshaw M, Cooper L, Papazisis K, Coleman J, Bohnenkamp H, et al. (2008) Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells. Breast Cancer Res 10: R52.
    • (2008) Breast Cancer Res , vol.10
    • Grimshaw, M.1    Cooper, L.2    Papazisis, K.3    Coleman, J.4    Bohnenkamp, H.5
  • 49
    • 0036668285 scopus 로고    scopus 로고
    • Matching SOX: Partner proteins and co-factors of the SOX family of transcriptional regulators
    • DOI 10.1016/S0959-437X(02)00323-4
    • Wilson M, Koopman P (2002) Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators. Curr Opin in Genet Dev 12: 441-446. (Pubitemid 34722924)
    • (2002) Current Opinion in Genetics and Development , vol.12 , Issue.4 , pp. 441-446
    • Wilson, M.1    Koopman, P.2
  • 52
    • 34247887724 scopus 로고    scopus 로고
    • Elevating the levels of Sox2 in embryonal carcinoma cells and embryonic stem cells inhibits the expression of Sox2:Oct-3/4 target genes
    • DOI 10.1093/nar/gkm059
    • Boer B, Kopp J, Mallanna S, Desler M, Chakravarthy H, et al. (2007) Elevating the levels of Sox2 in embryonal carcinoma cells and embryonic stem cells inhibits the expression of Sox2:Oct-3/4 target genes. Nucleic Acids Res 35: 1773-1786. (Pubitemid 47061649)
    • (2007) Nucleic Acids Research , vol.35 , Issue.6 , pp. 1773-1786
    • Boer, B.1    Kopp, J.2    Mallanna, S.3    Desler, M.4    Chakravarthy, H.5    Wilder, P.J.6    Bernadt, C.7    Rizzino, A.8
  • 54
    • 84903961151 scopus 로고    scopus 로고
    • mTOR signaling in endocrine resistance growth control. The Research and Biology of Cancer
    • Fung G, editor. iConcept Press Ltd. In press
    • Leung E, Baguley B (2014) mTOR signaling in endocrine resistance growth control. The Research and Biology of Cancer. In: Fung G, editor. Breast, Cervical and Prostate Cancer: iConcept Press Ltd. pp. In press.
    • (2014) Breast, Cervical and Prostate Cancer
    • Leung, E.1    Baguley, B.2
  • 55
    • 84890853243 scopus 로고    scopus 로고
    • The effect of a thieno[2,3-b] pyridine PLC-gamma inhibitor on the proliferation, morphology, migration and cell cycle of breast cancer cells
    • Leung E, Hung JM, Barker D, Reynisson J (2014) The effect of a thieno[2,3-b] pyridine PLC-gamma inhibitor on the proliferation, morphology, migration and cell cycle of breast cancer cells. MedChemComm 5: 99-106.
    • (2014) MedChemComm , vol.5 , pp. 99-106
    • Leung, E.1    Hung, J.M.2    Barker, D.3    Reynisson, J.4
  • 56
    • 84897848762 scopus 로고    scopus 로고
    • Evidence for the existence of triple-negative variants in the MCF-7 breast cancer cell population
    • Leung E, Kim JE, Askarian-Amiri M, Finlay GJ, Baguley BC (2014) Evidence for the existence of triple-negative variants in the MCF-7 breast cancer cell population. Biomed Res Int 2014: 836769.
    • (2014) Biomed Res Int , vol.2014 , pp. 836769
    • Leung, E.1    Kim, J.E.2    Askarian-Amiri, M.3    Finlay, G.J.4    Baguley, B.C.5
  • 57
    • 84875507118 scopus 로고    scopus 로고
    • Identification of cyclohexanone derivatives that act as catalytic inhibitors of topoisomerase I: Effects on tamoxifen-resistant MCF-7 cancer cells
    • Leung E, Rewcastle GW, Joseph WR, Rosengren RJ, Larsen L, et al. (2012) Identification of cyclohexanone derivatives that act as catalytic inhibitors of topoisomerase I: effects on tamoxifen-resistant MCF-7 cancer cells. Inves New Drugs 30: 2103-2112.
    • (2012) Inves New Drugs , vol.30 , pp. 2103-2112
    • Leung, E.1    Rewcastle, G.W.2    Joseph, W.R.3    Rosengren, R.J.4    Larsen, L.5
  • 58
    • 84884849331 scopus 로고    scopus 로고
    • Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway
    • Corominas-Faja B, Cufi S, Oliveras-Ferraros C, Cuyas E, Lopez-Bonet E, et al. (2013) Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway. Cell Cycle 12: 3109-3124.
    • (2013) Cell Cycle , vol.12 , pp. 3109-3124
    • Corominas-Faja, B.1    Cufi, S.2    Oliveras-Ferraros, C.3    Cuyas, E.4    Lopez-Bonet, E.5
  • 59
    • 66049149059 scopus 로고    scopus 로고
    • mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells
    • Zhou J, Su P, Wang L, Chen J, Zimmermann M, et al. (2009) mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells. Proc Natl Acad Sci U S A 106: 7840-7845.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 7840-7845
    • Zhou, J.1    Su, P.2    Wang, L.3    Chen, J.4    Zimmermann, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.