DRP1 Suppresses Leptin and Glucose Sensing of POMC Neurons

Cell Metabolism

Volumn 25, Issue 3, 2017, Pages 647-660

  Santoro, Anna ^a   Campolo, Michela ^a   Liu, Chen ^b   Sesaki, Hiromi ^c   Meli, Rosaria ^a,d   Liu, Zhong Wu ^a   Kim, Jung Dae ^a   Diano, Sabrina ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

counter regulatory responses to hypoglycemia; Drp1; glucose sensing; leptin; mitochondrial fission; POMC neurons

Indexed keywords

DYNAMIN; DYNAMIN RELATED PROTEIN 1; GLUCOSE; LEPTIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PROOPIOMELANOCORTIN; UNCLASSIFIED DRUG; DNM1L PROTEIN, MOUSE; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY COMPOSITION; BODY WEIGHT; CELL DENSITY; COMPARATIVE STUDY; CONTROLLED STUDY; DIET RESTRICTION; ELECTROPHYSIOLOGICAL PROCEDURES; FAT MASS; FEMALE; FOOD INTAKE; GLUCOSE METABOLISM; GLUCOSE TOLERANCE TEST; HYPOGLYCEMIA; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL VOLUME; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROBABILITY; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL; C57BL MOUSE; ENERGY METABOLISM; FEEDING BEHAVIOR; GENE DELETION; GENETICS; METABOLISM; MITOCHONDRION; PATHOLOGY; ULTRASTRUCTURE;

ANIMALS; DYNAMINS; ENERGY METABOLISM; FEEDING BEHAVIOR; GENE DELETION; GLUCOSE; HYPOGLYCEMIA; LEPTIN; MICE, INBRED C57BL; MITOCHONDRIA; NEURONS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PPAR GAMMA; PRO-OPIOMELANOCORTIN; REACTIVE OXYGEN SPECIES; RNA, MESSENGER;

EID: 85012925584     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2017.01.003     Document Type: Article

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