-
1
-
-
62849104641
-
Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study
-
Fenaux P., Mufti G.J., Hellstrom-Lindberg E., Santini V., Finelli C., Giagounidis A., et al. Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol 2009, 10:223-232.
-
(2009)
Lancet Oncol
, vol.10
, pp. 223-232
-
-
Fenaux, P.1
Mufti, G.J.2
Hellstrom-Lindberg, E.3
Santini, V.4
Finelli, C.5
Giagounidis, A.6
-
2
-
-
77449149371
-
DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes
-
Shen L., Kantarjian H., Guo Y., Lin E., Shan J., Huang X., et al. DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes. J Clin Oncol 2010, 28:605-613.
-
(2010)
J Clin Oncol
, vol.28
, pp. 605-613
-
-
Shen, L.1
Kantarjian, H.2
Guo, Y.3
Lin, E.4
Shan, J.5
Huang, X.6
-
3
-
-
79960207573
-
Prognostic significance of monosomal karyotype in higher risk myelodysplastic syndrome treated with azacitidine
-
Itzykson R., Thepot S., Eclache V., Quesnel B., Dreyfus F., Beyne-Rauzy O., et al. Prognostic significance of monosomal karyotype in higher risk myelodysplastic syndrome treated with azacitidine. Leukemia 2011, 25:1207-1209.
-
(2011)
Leukemia
, vol.25
, pp. 1207-1209
-
-
Itzykson, R.1
Thepot, S.2
Eclache, V.3
Quesnel, B.4
Dreyfus, F.5
Beyne-Rauzy, O.6
-
4
-
-
78650172030
-
Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine
-
Itzykson R., Thépot S., Quesnel B., Dreyfus F., Beyne-Rauzy O., Turlure P., et al. Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine. Blood 2011, 117:403-411.
-
(2011)
Blood
, vol.117
, pp. 403-411
-
-
Itzykson, R.1
Thépot, S.2
Quesnel, B.3
Dreyfus, F.4
Beyne-Rauzy, O.5
Turlure, P.6
-
5
-
-
84871063591
-
The revised IPSS is a powerful tool to evaluate the outcome of MDS patients treated with azacitidine: the GFM experience
-
Lamarque M., Raynaud S., Itzykson R., Thepot S., Quesnel B., Dreyfus F., et al. The revised IPSS is a powerful tool to evaluate the outcome of MDS patients treated with azacitidine: the GFM experience. Blood 2012, 120:5084-5085.
-
(2012)
Blood
, vol.120
, pp. 5084-5085
-
-
Lamarque, M.1
Raynaud, S.2
Itzykson, R.3
Thepot, S.4
Quesnel, B.5
Dreyfus, F.6
-
6
-
-
79960229916
-
Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias
-
Itzykson R., Kosmider O., Cluzeau T., Mansat-De Mas V., Dreyfus F., Beyne-Rauzy O., et al. Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias. Leukemia 2011, 25:1147-1152.
-
(2011)
Leukemia
, vol.25
, pp. 1147-1152
-
-
Itzykson, R.1
Kosmider, O.2
Cluzeau, T.3
Mansat-De Mas, V.4
Dreyfus, F.5
Beyne-Rauzy, O.6
-
7
-
-
84857238789
-
Impact of molecular mutations on treatment response to hypomethylating agents in MDS
-
Traina F., Jankowska A.M., Visconte V., Sugimoto Y., Szpurka H., Makishima H., et al. Impact of molecular mutations on treatment response to hypomethylating agents in MDS. ASH Annual Meeting Abstracts, vol. 118 2011, 461.
-
(2011)
ASH Annual Meeting Abstracts, vol. 118
, pp. 461
-
-
Traina, F.1
Jankowska, A.M.2
Visconte, V.3
Sugimoto, Y.4
Szpurka, H.5
Makishima, H.6
-
8
-
-
0026336513
-
Mutations in the p53 gene in myelodysplastic syndromes
-
Jonveaux P., Fenaux P., Quiquandon I., Pignon J.M., Laï J.L., Loucheux-Lefebvre M.H., et al. Mutations in the p53 gene in myelodysplastic syndromes. Oncogene 1991, 6:2243-2247.
-
(1991)
Oncogene
, vol.6
, pp. 2243-2247
-
-
Jonveaux, P.1
Fenaux, P.2
Quiquandon, I.3
Pignon, J.M.4
Laï, J.L.5
Loucheux-Lefebvre, M.H.6
-
9
-
-
0026528809
-
Mutations of the P53 gene in acute myeloid leukaemia
-
Fenaux P., Preudhomme C., Quiquandon I., Jonveaux P., Laï J.L., Vanrumbeke M., et al. Mutations of the P53 gene in acute myeloid leukaemia. Br J Haematol 1992, 80:178-183.
-
(1992)
Br J Haematol
, vol.80
, pp. 178-183
-
-
Fenaux, P.1
Preudhomme, C.2
Quiquandon, I.3
Jonveaux, P.4
Laï, J.L.5
Vanrumbeke, M.6
-
10
-
-
49349140725
-
Mutations of the TP53 gene in acute myeloid leukemia are strongly associated with a complex aberrant karyotype
-
Haferlach C., Dicker F., Herholz H., Schnittger S., Kern W., Haferlach T. Mutations of the TP53 gene in acute myeloid leukemia are strongly associated with a complex aberrant karyotype. Leukemia 2008, 22:1539-1541.
-
(2008)
Leukemia
, vol.22
, pp. 1539-1541
-
-
Haferlach, C.1
Dicker, F.2
Herholz, H.3
Schnittger, S.4
Kern, W.5
Haferlach, T.6
-
11
-
-
79952164235
-
Unraveling the molecular pathophysiology of myelodysplastic syndromes
-
Bejar R., Levine R., Ebert B.L. Unraveling the molecular pathophysiology of myelodysplastic syndromes. J Clin Oncol 2011, 29:504-515.
-
(2011)
J Clin Oncol
, vol.29
, pp. 504-515
-
-
Bejar, R.1
Levine, R.2
Ebert, B.L.3
-
12
-
-
79959794787
-
Clinical effect of point mutations in myelodysplastic syndromes
-
Bejar R., Stevenson K., Abdel-Wahab O., Galili N., Nilsson B., Garcia-Manero G., et al. Clinical effect of point mutations in myelodysplastic syndromes. N Engl J Med 2011, 364:2496-2506.
-
(2011)
N Engl J Med
, vol.364
, pp. 2496-2506
-
-
Bejar, R.1
Stevenson, K.2
Abdel-Wahab, O.3
Galili, N.4
Nilsson, B.5
Garcia-Manero, G.6
-
13
-
-
84873995626
-
TP53 mutations in myelodysplastic syndrome are strongly correlated with aberrations of chromosome 5, and correlate with adverse prognosis
-
Kulasekararaj A.G., Smith A.E., Mian S.A., Mohamedali A.M., Krishnamurthy P., Lea N.C., et al. TP53 mutations in myelodysplastic syndrome are strongly correlated with aberrations of chromosome 5, and correlate with adverse prognosis. Br J Haematol 2013, 160:660-672.
-
(2013)
Br J Haematol
, vol.160
, pp. 660-672
-
-
Kulasekararaj, A.G.1
Smith, A.E.2
Mian, S.A.3
Mohamedali, A.M.4
Krishnamurthy, P.5
Lea, N.C.6
-
14
-
-
79956291339
-
TP53 mutations in low-risk myelodysplastic syndromes with del(5q) predict disease progression
-
Jädersten M., Saft L., Smith A., Kulasekararaj A., Pomplun S., Göhring G., et al. TP53 mutations in low-risk myelodysplastic syndromes with del(5q) predict disease progression. J Clin Oncol 2011, 29:1971-1979.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1971-1979
-
-
Jädersten, M.1
Saft, L.2
Smith, A.3
Kulasekararaj, A.4
Pomplun, S.5
Göhring, G.6
-
15
-
-
0028575432
-
Inactivation of the p53 gene in leukemias and myelodysplastic syndrome (MDS) with 17p monosomy
-
Preudhomme C., Vanrumbeke M., Lai J.L., Lepelley P., Wattel E., Fenaux P. Inactivation of the p53 gene in leukemias and myelodysplastic syndrome (MDS) with 17p monosomy. Leukemia 1994, 8:2241-2242.
-
(1994)
Leukemia
, vol.8
, pp. 2241-2242
-
-
Preudhomme, C.1
Vanrumbeke, M.2
Lai, J.L.3
Lepelley, P.4
Wattel, E.5
Fenaux, P.6
-
16
-
-
0028928283
-
Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion. An entity characterized by specific dysgranulopoïesis and a high incidence of P53 mutations
-
Lai J.L., Preudhomme C., Zandecki M., Flactif M., Vanrumbeke M., Lepelley P., et al. Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion. An entity characterized by specific dysgranulopoïesis and a high incidence of P53 mutations. Leukemia 1995, 9:370-381.
-
(1995)
Leukemia
, vol.9
, pp. 370-381
-
-
Lai, J.L.1
Preudhomme, C.2
Zandecki, M.3
Flactif, M.4
Vanrumbeke, M.5
Lepelley, P.6
-
17
-
-
0032006824
-
17p deletion in acute myeloid leukemia and myelodysplastic syndrome. Analysis of breakpoints and deleted segments by fluorescence in situ
-
Soenen V., Preudhomme C., Roumier C., Daudignon A., Laï J.L., Fenaux P. 17p deletion in acute myeloid leukemia and myelodysplastic syndrome. Analysis of breakpoints and deleted segments by fluorescence in situ. Blood 1998, 91:1008-1015.
-
(1998)
Blood
, vol.91
, pp. 1008-1015
-
-
Soenen, V.1
Preudhomme, C.2
Roumier, C.3
Daudignon, A.4
Laï, J.L.5
Fenaux, P.6
-
18
-
-
0028172868
-
P53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies
-
Wattel E., Preudhomme C., Hecquet B., Vanrumbeke M., Quesnel B., Dervite I., et al. p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies. Blood 1994, 84:3148-3157.
-
(1994)
Blood
, vol.84
, pp. 3148-3157
-
-
Wattel, E.1
Preudhomme, C.2
Hecquet, B.3
Vanrumbeke, M.4
Quesnel, B.5
Dervite, I.6
-
19
-
-
0029043805
-
A simple P53 functional assay for screening cell lines, blood, and tumors
-
Flaman J.M., Frebourg T., Moreau V., Charbonnier F., Martin C., Chappuis P., et al. A simple P53 functional assay for screening cell lines, blood, and tumors. PNAS 1995, 92:3963-3967.
-
(1995)
PNAS
, vol.92
, pp. 3963-3967
-
-
Flaman, J.M.1
Frebourg, T.2
Moreau, V.3
Charbonnier, F.4
Martin, C.5
Chappuis, P.6
-
20
-
-
58349094961
-
High frequency of TP53 mutation in BRCA1 and sporadic basal-like carcinomas but not in BRCA1 luminal breast tumors
-
Manié E., Vincent-Salomon A., Lehmann-Che J., Pierron G., Turpin E., Warcoin M., et al. High frequency of TP53 mutation in BRCA1 and sporadic basal-like carcinomas but not in BRCA1 luminal breast tumors. Cancer Res 2009, 69:663-671.
-
(2009)
Cancer Res
, vol.69
, pp. 663-671
-
-
Manié, E.1
Vincent-Salomon, A.2
Lehmann-Che, J.3
Pierron, G.4
Turpin, E.5
Warcoin, M.6
-
21
-
-
83555166249
-
The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium involving 10 laboratories
-
Kohlmann A., Klein H.-U., Weissmann S., Bresolin S., Chaplin T., Cuppens H., et al. The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium involving 10 laboratories. Leukemia 2011, 25:1840-1848.
-
(2011)
Leukemia
, vol.25
, pp. 1840-1848
-
-
Kohlmann, A.1
Klein, H.-U.2
Weissmann, S.3
Bresolin, S.4
Chaplin, T.5
Cuppens, H.6
-
22
-
-
33749438404
-
Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion
-
List A., Dewald G., Bennett J., Giagounidis A., Raza A., Feldman E., et al. Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion. N Engl J Med 2006, 355:1456-1465.
-
(2006)
N Engl J Med
, vol.355
, pp. 1456-1465
-
-
List, A.1
Dewald, G.2
Bennett, J.3
Giagounidis, A.4
Raza, A.5
Feldman, E.6
-
23
-
-
80053621748
-
A randomized phase 3 study of lenalidomide versus placebo in RBC transfusion-dependent patients with low-/intermediate-1-risk myelodysplastic syndromes with del5q
-
Fenaux P., Giagounidis A., Selleslag D., Beyne-Rauzy O., Mufti G., Mittelman M., et al. A randomized phase 3 study of lenalidomide versus placebo in RBC transfusion-dependent patients with low-/intermediate-1-risk myelodysplastic syndromes with del5q. Blood 2011, 118:3765-3776.
-
(2011)
Blood
, vol.118
, pp. 3765-3776
-
-
Fenaux, P.1
Giagounidis, A.2
Selleslag, D.3
Beyne-Rauzy, O.4
Mufti, G.5
Mittelman, M.6
-
24
-
-
84878924059
-
Long-term outcome of anemic lower-risk myelodysplastic syndromes without 5q deletion refractory to or relapsing after erythropoiesis-stimulating agents
-
Kelaidi C., Park S., Sapena R., Beyne-Rauzy O., Coiteux V., Vey N., et al. Long-term outcome of anemic lower-risk myelodysplastic syndromes without 5q deletion refractory to or relapsing after erythropoiesis-stimulating agents. Leukemia 2013, 27:1283-1290.
-
(2013)
Leukemia
, vol.27
, pp. 1283-1290
-
-
Kelaidi, C.1
Park, S.2
Sapena, R.3
Beyne-Rauzy, O.4
Coiteux, V.5
Vey, N.6
-
25
-
-
0038798668
-
Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression
-
Oshiro M.M., Watts G.S., Wozniak R.J., Junk D.J., Munoz-Rodriguez J.L., Domann F.E., et al. Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression. Oncogene 2003, 22:3624-3634.
-
(2003)
Oncogene
, vol.22
, pp. 3624-3634
-
-
Oshiro, M.M.1
Watts, G.S.2
Wozniak, R.J.3
Junk, D.J.4
Munoz-Rodriguez, J.L.5
Domann, F.E.6
-
26
-
-
0037457012
-
Mutations of TP53 induce loss of DNA methylation and amplification of the TROP1 gene
-
Nasr A.F., Nutini M., Palombo B., Guerra E., Alberti S. Mutations of TP53 induce loss of DNA methylation and amplification of the TROP1 gene. Oncogene 2003, 22:1668-1677.
-
(2003)
Oncogene
, vol.22
, pp. 1668-1677
-
-
Nasr, A.F.1
Nutini, M.2
Palombo, B.3
Guerra, E.4
Alberti, S.5
-
27
-
-
0035057219
-
Activation of the P53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine
-
Karpf A.R., Moore B.C., Ririe T.O., Jones D.A. Activation of the P53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine. Mol Pharmacol 2001, 59:751-757.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 751-757
-
-
Karpf, A.R.1
Moore, B.C.2
Ririe, T.O.3
Jones, D.A.4
-
28
-
-
84860827822
-
5-Azacytidine and decitabine exert proapoptotic effects on neoplastic mast cells: role of FAS-demethylation and FAS re-expression, and synergism with FAS-ligand
-
Ghanim V., Herrmann H., Heller G., Peter B., Hadzijusufovic E., Blatt K., et al. 5-Azacytidine and decitabine exert proapoptotic effects on neoplastic mast cells: role of FAS-demethylation and FAS re-expression, and synergism with FAS-ligand. Blood 2012, 119:4242-4252.
-
(2012)
Blood
, vol.119
, pp. 4242-4252
-
-
Ghanim, V.1
Herrmann, H.2
Heller, G.3
Peter, B.4
Hadzijusufovic, E.5
Blatt, K.6
-
29
-
-
78650710470
-
Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy
-
Schnekenburger M., Grandjenette C., Ghelfi J., Karius T., Foliguet B., Dicato M., et al. Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy. Biochem Pharmacol 2011, 81:364-378.
-
(2011)
Biochem Pharmacol
, vol.81
, pp. 364-378
-
-
Schnekenburger, M.1
Grandjenette, C.2
Ghelfi, J.3
Karius, T.4
Foliguet, B.5
Dicato, M.6
|