Parkinson's disease alters multisensory perception: Insights from the Rubber Hand Illusion

Neuropsychologia

Volumn 97, Issue , 2017, Pages 38-45

  Ding, Catherine ^a   Palmer, Colin J ^b   Hohwy, Jakob ^b   Youssef, George J ^c   Paton, Bryan ^b   Tsuchiya, Naotsugu ^b   Stout, Julie C ^b   Thyagarajan, Dominic ^a  

^a SOUTHERN HEALTH   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c DEAKIN UNIVERSITY   (Australia)

Author keywords

Body ownership; Multisensory perception; Parkinson's disease; Rubber Hand Illusion

Indexed keywords

ANTIPARKINSON AGENT; DOPAMINE RECEPTOR STIMULATING AGENT; LEVODOPA;

AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; DISEASE SEVERITY; DOPAMINERGIC TRANSMISSION; FEMALE; HUMAN; ILLUSION; MALE; PARKINSON DISEASE; PERCEPTION; PROPRIOCEPTION; RUBBER HAND ILLUSION; COMPLICATION; MIDDLE AGED; PERCEPTION DISORDER; PHYSIOLOGY; TOUCH;

AGED; FEMALE; HUMANS; ILLUSIONS; MALE; MIDDLE AGED; PARKINSON DISEASE; PERCEPTUAL DISORDERS; PROPRIOCEPTION; TOUCH PERCEPTION;

EID: 85011976753     PISSN: 00283932     EISSN: 18733514     Source Type: Journal    
DOI: 10.1016/j.neuropsychologia.2017.01.031     Document Type: Article

References (55)

1. Adamovich, S.V., Berkinblit, M.B., Hening, W., Sage, J., Poizner, H., The interaction of visual and proprioceptive inputs in pointing to actual and remembered targets in Parkinson's disease. Neuroscience 104 (2001), 1027–1041.
2. Albrecht, M.A., Martin-Iverson, M.T., Price, G., Lee, J., Iyyalol, R., Waters, F., Dexamphetamine effects on separate constructs in the rubber hand illusion test. Psychopharmacology 217 (2011), 39–50.
3. Artieda, J., Pastor, M.A., Lacruz, F., Obeso, J.A., Temporal discrimination is abnormal in Parkinson's disease. Brain 115:Pt 1 (1992), 199–210.
4. Bates, D., Maechler, M., Bolker, B., Walker, S., 2014. lme4: Linear mixed-effects models using Eigen and S4. R package version 1.1-7 [WWW Document]. URL (http://CRAN.R-project.org/package=lme4) (accessed 7.19.16).
5. Bekrater-Bodmann, R., Foell, J., Diers, M., Kamping, S., Rance, M., Kirsch, P., Trojan, J., Fuchs, X., Bach, F., Çakmak, H.K., Maaß, H., Flor, H., The importance of synchrony and temporal order of visual and tactile input for illusory limb ownership experiences - an FMRI study applying virtual reality. PLoS One, 9, 2014, e87013.
6. Blanke, O., Pozeg, P., Hara, M., Heydrich, L., Serino, A., Yamamoto, A., Higuchi, T., Salomon, R., Seeck, M., Landis, T., Arzy, S., Herbelin, B., Bleuler, H., Rognini, G., Neurological and robot-controlled induction of an apparition. Curr. Biol. 24 (2014), 2681–2686.
7. Botvinick, M., Cohen, J., Rubber hands “feel” touch that eyes see. Nature, 391, 1998, 756.
8. Braak, H., Heiko, B., Del Tredici, K., Udo, R., de Vos, R.A.I., Steur, E.N.H.J., Eva, B., Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol. Aging 24 (2003), 197–211.
9. Bulens, C., Meerwaldt, J.D., Van der Wildt, G.J., Van Deursen, J.B., Effect of levodopa treatment on contrast sensitivity in Parkinson's disease. Ann. Neurol. 22 (1987), 365–369.
10. Büttner, T., Kuhn, W., Müller, T., Welter, F.L., Federlein, J., Heidbrink, K., Przuntek, H., Visual hallucinosis: the major clinical determinant of distorted chromatic contour perception in Parkinson's disease. J. Neural Transm. 103 (1996), 1195–1204.
11. Büttner, T., Kuhn, W., Patzold, T., Przuntek, H., L-dopa improves colour vision in Parkinson's disease. J. Neural Transm. Park. Dis. Dement. Sect. 7 (1994), 13–19.
12. Conte, A., Khan, N., Defazio, G., Rothwell, J.C., Berardelli, A., Pathophysiology of somatosensory abnormalities in Parkinson disease. Nat. Rev. Neurol. 9 (2013), 687–697.
13. De Rosario-Martinez, H., 2015. phia: Post-Hoc Interaction Analysis R package version 0.2‐1 [WWW Document]. URL (http://CRAN.R-project.org/package=phia) (accessed 7.19.16).
14. Ehrsson, H.H., The Concept of Body Ownership And its Relation to Multi-sensory integration. In the New Handbook of Multisensory Processing. 2012, MIT Press, Cambridge, MA.
15. Ehrsson, H.H., Holmes, N.P., Passingham, R.E., Touching a rubber hand: feeling of body ownership is associated with activity in multisensory brain areas. J. Neurosci. 25 (2005), 10564–10573.
16. Ehrsson, H.H., Spence, C., Passingham, R.E., That's my hand! Activity in premotor cortex reflects feeling of ownership of a limb. Science 305 (2004), 875–877.
17. Fénelon, G., Mahieux, F., Huon, R., Ziégler, M., Hallucinations in Parkinson's disease: prevalence, phenomenology and risk factors. Brain 123:Pt 4 (2000), 733–745.
18. Fox, J., Effects: effect displays in R for generalised linear models. J. Stat. Softw. 8:15 (2003), 1–27 (http://www.jstatsoft.org/v08/i15/) (accessed 7.19.16).
19. Fox, J., Hong, J., Effects: effect displays in R for multinomial and proportional-odds logit models: extensions to the effects package. J. Stat. Softw. 32:1 (2009), 1–24 (http://www.jstatsoft.org/v32/i01/) (accessed 7.19.16).
20. Graham, K.T., Martin-Iverson, M.T., Holmes, N.P., Jablensky, A., Waters, F., Deficits in agency in schizophrenia, and additional deficits in body image, body schema, and internal timing, in passivity symptoms. Front. Psychiatry, 5, 2014, 126.
21. Harding, A.J., Broe, G.A., Halliday, G.M., Visual hallucinations in Lewy body disease relate to Lewy bodies in the temporal lobe. Brain 125 (2002), 391–403.
22. Heed, T., Gründler, M., Rinkleib, J., Rudzik, F.H., Collins, T., Cooke, E., O'Regan, J.K., Visual information and rubber hand embodiment differentially affect reach-to-grasp actions. Acta Psychol. 138 (2011), 263–271.
23. Hughes, A.J., Daniel, S.E., Kilford, L., Lees, A.J., Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J. Neurol. Neurosurg. Psychiatry 55 (1992), 181–184.
24. Kalia, L.V., Lang, A.E., Parkinson's disease. Lancet 386 (2015), 896–912.
25. Kammers, M.P.M., de Vignemont, F., Verhagen, L., Dijkerman, H.C., The rubber hand illusion in action. Neuropsychologia 47 (2009), 204–211.
26. Kammers, M.P.M., Kootker, J.A., Hogendoorn, H., Dijkerman, H.C., How many motoric body representations can we grasp?. Exp. Brain Res. 202 (2010), 203–212.
27. Kammers, M.P.M., Longo, M.R., Tsakiris, M., Dijkerman, H.C., Haggard, P., Specificity and coherence of body representations. Perception 38 (2009), 1804–1820.
28. Kammers, M.P.M., van der Ham, I.J.M., Dijkerman, H.C., Dissociating body representations in healthy individuals: differential effects of a kinaesthetic illusion on perception and action. Neuropsychologia 44 (2006), 2430–2436.
29. Kaplan, R.A., Enticott, P.G., Hohwy, J., Castle, D.J., Rossell, S.L., Is body dysmorphic disorder associated with abnormal bodily self-awareness? A study using the rubber hand illusion. PLoS One, 9, 2014, e99981.
30. Krystal, J.H., Perry, E.B. Jr, Gueorguieva, R., Belger, A., Madonick, S.H., Abi-Dargham, A., Cooper, T.B., Macdougall, L., Abi-Saab, W., D'Souza, D.C., Comparative and interactive human psychopharmacologic effects of ketamine and amphetamine: implications for glutamatergic and dopaminergic model psychoses and cognitive function. Arch. Gen. Psychiatry 62 (2005), 985–994.
31. Limanowski, J., Jakub, L., Felix, B., That's not quite me: limb ownership encoding in the brain. Soc. Cogn. Affect. Neurosci., 2015, nsv079.
32. Maschke, M., Gomez, C.M., Tuite, P.J., Konczak, J., Dysfunction of the basal ganglia, but not the cerebellum, impairs kinaesthesia. Brain 126 (2003), 2312–2322.
33. Morgan, H.L., Turner, D.C., Corlett, P.R., Absalom, A.R., Adapa, R., Arana, F.S., Pigott, J., Gardner, J., Everitt, J., Haggard, P., Fletcher, P.C., Exploring the impact of ketamine on the experience of illusory body ownership. Biol. Psychiatry 69 (2011), 35–41.
34. Moskovitz, C., Moses, H. 3rd, Klawans, H.L., Levodopa-induced psychosis: a kindling phenomenon. Am. J. Psychiatry 135 (1978), 669–675.
35. O'Suilleabhain, P., Bullard, J., Dewey, R.B., Proprioception in Parkinson's disease is acutely depressed by dopaminergic medications. J. Neurol. Neurosurg. Psychiatry 71 (2001), 607–610.
36. Pagonabarraga, J., Martinez-Horta, S., Fernández de Bobadilla, R., Pérez, J., Ribosa-Nogué, R., Marín, J., Pascual-Sedano, B., García, C., Gironell, A., Kulisevsky, J., Minor hallucinations occur in drug-naive Parkinson's disease patients, even from the premotor phase. Mov. Disord. 31 (2016), 45–52.
37. Palmer, C.J., Paton, B., Hohwy, J., Enticott, P.G., Movement under uncertainty: the effects of the rubber-hand illusion vary along the nonclinical autism spectrum. Neuropsychologia 51 (2013), 1942–1951.
38. Palmer, C.J., Paton, B., Kirkovski, M., Enticott, P.G., Hohwy, J., Context sensitivity in action decreases along the autism spectrum: a predictive processing perspective. Proc. Biol. Sci., 2015, 282, 10.1098/rspb.2014.1557.
39. Pastor, M.A., Artieda, J., Jahanshahi, M., Obeso, J.A., Time estimation and reproduction is abnormal in Parkinson's disease. Brain 115 (1992), 211–225.
40. Pavani, F., Spence, C., Driver, J., Visual capture of touch: out-of-the-body experiences with rubber gloves. Psychol. Sci. 11 (2000), 353–359.
41. Pinheiro, J., Bates, D., DebRoy, S., Sarkar, D., (Core Team, R.), 2014. nlme: Linear and Nonlinear Mixed Effects Models. R package version 3.1-117 [WWW Document]. URL (http://CRAN.R-project.org/package=nlme) (accessed 7.19.16).
42. Price, M.J., Feldman, R.G., Adelberg, D., Kayne, H., Abnormalities in color vision and contrast sensitivity in Parkinson's disease. Neurology 42 (1992), 887–890.
43. Rascol, O., Brooks, D.J., Korczyn, A.D., De Deyn, P.P., Clarke, C.E., Lang, A.E., A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa. N. Engl. J. Med 342 (2000), 1484–1491.
44. Ravina, B., Marder, K., Fernandez, H.H., Friedman, J.H., McDonald, W., Murphy, D., Aarsland, D., Babcock, D., Cummings, J., Endicott, J., Factor, S., Galpern, W., Lees, A., Marsh, L., Stacy, M., Gwinn-Hardy, K., Voon, V., Goetz, C., Diagnostic criteria for psychosis in Parkinson's disease: report of an NINDS. NIMH Work Group. Mov. Disord. 22 (2007), 1061–1068.
45. (R Core Team), 2014 (R Core Team), 2014. R: A language and environment for statistical computing [WWW Document]. URL (http://www.R-project.org/) (accessed 7.19.16).
46. Sacrey, L.-A.R., Travis, S.G., Whishaw, I.Q., Drug treatment and familiar music aids an attention shift from vision to somatosensation in Parkinson's disease on the reach-to-eat task. Behav. Brain Res. 217 (2011), 391–398.
47. Schaefer, M., Denke, C., Apostolova, I., Heinze, H.-J., Galazky, I., A case of right alien hand syndrome coexisting with right-sided tactile extinction. Front. Hum. Neurosci., 10, 2016, 105.
48. Schneider, J.S., Diamond, S.G., Markham, C.H., Parkinson's disease: sensory and motor problems in arms and hands. Neurology 37 (1987), 951–956.
49. Shimada, S., Fukuda, K., Hiraki, K., Rubber hand illusion under delayed visual feedback. PLoS One, 4, 2009, e6185.
50. “Suggestible” [WWW Document], 2015. c. Merriam-Webster dictionary. URL (http://www.merriam-webster.com/dictionary/suggestible) (accessed 8.8.16).
51. Thakkar, K.N., Nichols, H.S., McIntosh, L.G., Park, S., Disturbances in body ownership in schizophrenia: evidence from the rubber hand illusion and case study of a spontaneous out-of-body experience. PLoS One, 6, 2011, e27089.
52. Trommershauser, J., Kording, K., Landy, M.S., (eds.) Sensory Cue Integration, 2011, Oxford University Press, USA.
53. Wichmann, T., Delong, M.R., Neurocircuitry of Parkinson's disease. Davis, K.L., Charney, D., Coyle, J.T., Nemeroff, C., (American College ofNeuropsychopharmacology), (eds.) Neuropsychopharmacology: The Fifth Generation of Progress, 2002, Lippincott Williams & Wilkins, 1761–1779.
54. Wood, R.A., Hopkins, S.A., Moodley, K.K., Chan, D., Fifty percent prevalence of extracampine hallucinations in Parkinson's disease patients. Front. Neurol., 6, 2015, 263.
55. Zopf, R., Truong, S., Finkbeiner, M., Friedman, J., Williams, M.A., Viewing and feeling touch modulates hand position for reaching. Neuropsychologia 49 (2011), 1287–1293.