A fermented milk concentrate and a combination of short-chain galacto-oligosaccharides/long-chain fructo-oligosaccharides/pectin-derived acidic oligosaccharides protect suckling rats from rotavirus gastroenteritis

British Journal of Nutrition

Volumn 117, Issue 2, 2017, Pages 209-217

  Rigo Adrover, Mar ^a,b   Pérez Berezo, Teresa ^a,b   Ramos Romero, Sara ^a,b   Van Limpt, Kees ^c   Knipping, Karen ^c,d   Garssen, Johan ^c,d   Knol, Jan ^c   Franch, Àngels ^a,b   Castell, Margarida ^a,b   Pérez Cano, Francisco J ^a,b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Institut de Recerca en Nutrició i Seguretat Alimentària de la UB INSA UB   (Spain)

^c DANONE NUTRICIA RESEARCH   (Netherlands)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Fermented formula; Fructo oligosaccharides; Galacto oligosaccharides; Milk; Pectin derived acidic oligosaccharides; Prebiotics; Rotavirus

Indexed keywords

ACIDIC OLIGOSACCHARIDE; FRUCTOSE OLIGOSACCHARIDE; GALACTOSE OLIGOSACCHARIDE; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; OLIGOSACCHARIDE; PECTIN; PREBIOTIC AGENT; UNCLASSIFIED DRUG; FRUCTOSE; GALACTOSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIFIDOBACTERIUM BREVE; BODY WEIGHT; CONTROLLED STUDY; DIARRHEA; DIET SUPPLEMENTATION; DISEASE SEVERITY; FERMENTED MILK PRODUCT; IMMUNOMODULATION; IN VITRO STUDY; NEWBORN; NONHUMAN; RAT; ROTAVIRUS INFECTION; STREPTOCOCCUS THERMOPHILUS; SUCKLING ANIMAL; VIRAL GASTROENTERITIS; VIRUS SHEDDING; ANIMAL; ARTIFICIAL MILK; BACTERIUM; BIFIDOBACTERIUM; BREAST FEEDING; BREAST MILK; CHEMISTRY; COMPLICATION; DIETARY SUPPLEMENT; FERMENTATION; GASTROENTERITIS; HUMAN; INFANT; INFANT NUTRITION; MICROBIOLOGY; MILK; ROTAVIRUS; VIROLOGY;

ANIMALS; ANIMALS, NEWBORN; BACTERIA; BIFIDOBACTERIUM; BREAST FEEDING; DIETARY SUPPLEMENTS; FERMENTATION; FRUCTOSE; GALACTOSE; GASTROENTERITIS; HUMANS; INFANT; INFANT FORMULA; INFANT NUTRITIONAL PHYSIOLOGICAL PHENOMENA; MILK; MILK, HUMAN; OLIGOSACCHARIDES; PECTINS; RATS; ROTAVIRUS; ROTAVIRUS INFECTIONS; STREPTOCOCCUS THERMOPHILUS; VIRUS SHEDDING;

EID: 85011884600     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114516004566     Document Type: Article

References (37)

1. World Health Organization & UNICEF (2003) Global Strategy for Infant and Young Child Feeding. Geneva: WHO. http:// apps.who.int/iris/bitstream/10665/42590/1/9241562218.pdf?ua=1&ua=1 (accessed May 2016).
2. Krawczyk A, Lewis MG, Venkatesh BT, et al. (2016) Effect of exclusive breastfeeding on rotavirus infection among children. Indian J Pediatr 83, 220-225.
3. Jeurink PV, Van Esch BCAM, Rijnierse A, et al. (2013) Mechanisms underlying immune effects of dietary oligosaccharides. Am J Clin Nutr 98, 572-577.
4. Pérez-Cano FJ, Marín-Gallén S, Castell M, et al. (2008) Supplementing suckling rats with whey protein concentrate modulates the immune response and ameliorates rat rotavirusinduced diarrhea. J Nutr 138, 2392-2398.
5. Salvatore S & Vandenplas Y (2010) Prebiotics and probiotics in therapy and prevention of gastrointestinal diseases in children. In Bioactive Foods in Promoting Health, pp. 181-203 [RR Watson and VR Preedy, editors]. Amsterdam: Elsevier.
6. Veereman-Wauters G, Staelens S, Van de Broek H, et al. (2011) Physiological and bifidogenic effects of prebiotic supplements in infant formulae. J Pediatr Gastroenterol Nutr 52, 763-771.
7. Djouzi Z & Andrieux C (1997) Compared effects of three oligosaccharides on metabolism of intestinal microflora in rats inoculated with a human faecal flora. Br J Nutr 78, 313-324.
8. Pan X, Chen F, Wu T, et al. (2009) Prebiotic oligosaccharides change the concentrations of short-chain fatty acids and the microbial population of mouse bowel. J Zhejiang Univ Sci B 10, 258-263.
9. Bakker-Zierikzee AM, Van Tol EAF, Kroes H, et al. (2006) Faecal SIgA secretion in infants fed on pre-or probiotic infant formula. Pediatr Allergy Immunol 17, 134-140.
10. Scholtens PAMJ, Alliet P, Raes M, et al. (2008) Fecal secretory immunoglobulin A is increased in healthy infants who receive a formula with short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides. J Nutr 138, 1141-1147.
11. Bryk G, Coronel MZ, Pellegrini G, et al. (2015) Effect of a combination GOS/FOS® prebiotic mixture and interaction with calcium intake on mineral absorption and bone parameters in growing rats. Eur J Nutr 54, 913-923.
12. Bryk G, Hernandez E, Chaves MG, et al. (2015) Utilidad de una mezcla prebiótica para aumentar la absorción y retención de calcio durante el crecimiento normal y durante la recuperación de una malnutrición proteica: modelo experimental en ratas (Usefulness of a prebiotic mixture to increase calcium absorption and retention during normal growth and during recovery from protein malnutrition: experimental model in rats). Actual Osteol 11, 19-37.
13. Arslanoglu S, Moro GE & Boehm G (2007) Early supplementation of prebiotic oligosaccharides protects formula-fed infants against infections during the first 6 months of life. J Nutr 137, 2420-2424.
14. Bruzzese E, Volpicelli M, Squeglia V, et al. (2009) A formula containing galacto-and fructo-oligosaccharides prevents intestinal and extra-intestinal infections: an observational study. Clin Nutr 28, 156-161.
15. Osborn DA & Sinn JKH (2013) Prebiotics in infants for prevention of allergy. The Cochrane Database of Systematic Reviews, issue 3, CD006474.
16. Garthoff JA, Heemskerk S, Hempenius RA, et al. (2010) Safety evaluation of pectin-derived acidic oligosaccharides (pAOS): genotoxicity and sub-chronic studies. Regul Toxicol Pharmacol 57, 31-42.
17. Gori A, Rizzardini G, Van't Land B, et al. (2011) Specific prebiotics modulate gut microbiota and immune activation in HAART-naive HIV-infected adults: results of the COPA pilot randomized trial. Mucosal Immunol 4, 554-563.
18. Schijf MA, Kruijsen D, Bastiaans J, et al. (2012) Specific dietary oligosaccharides increase Th1 responses in a mouse respiratory syncytial virus infection model. J Virol 86, 11472-11482.
19. Vos AP, Haarman M, VanGinkel JWH, et al. (2007) Dietary supplementation of neutral and acidic oligosaccharides enhances Th1-dependent vaccination responses in mice. Pediatr Allergy Immunol 18, 304-312.
20. Kerperien J, Jeurink PV, Wehkamp T, et al. (2014) Non-digestible oligosaccharides modulate intestinal immune activation and suppress cow's milk allergic symptoms. Pediatr Allergy Immunol 25, 747-754.
21. Grüber C, van Stuijvenberg M, Mosca F, et al. (2010) Reduced occurrence of early atopic dermatitis because of immunoactive prebiotics among low-atopy-risk infants. J Allergy Clin Immunol 126, 791-797.
22. Granier A, Goulet O & Hoarau C (2013) Fermentation products: immunological effects on human and animal models. Pediatr Res 74, 238-244.
23. Romond MB, Ais A, Yazourh A, et al. (1997) Cell-free wheys from bifidobacteria fermented milks exert a regulatory effect on the intestinal microflora of mice and humans. Anaerobe 3, 137-143.
24. Romond MB, Ais A, Guillemot F, et al. (1998) Cell-free whey from milk fermented with bifidobacterium breve C50 used to modify the colonic microflora of healthy subjects. J Dairy Sci 81, 1229-1235.
25. Guérin-Danan C, Meslin JC, Chambard A, et al. (2001) Food supplementation with milk fermented by Lactobacillus casei DN-114 001 protects suckling rats from rotavirus-associated diarrhea. J Nutr 131, 111-117.
26. Thibault H, Aubert-Jacquin C & Goulet O (2004) Effects of long-term consumption of a fermented infant formula (with Bifidobacterium breve c50 and Streptococcus thermophilus 065) on acute diarrhea in healthy infants. J Pediatr Gastroenterol Nutr 39, 147-152.
27. Pérez-Cano FJ, Castell M, Castellote C, et al. (2007) Characterization of clinical and immune response in a rotavirus diarrhea model in suckling Lewis rats. Pediatr Res 62, 658-663.
28. Pérez-Cano FJ, Franch A, Castellote C, et al. (2012) The suckling rat as a model for immunonutrition studies in early life. Clin Dev Immunol 2012, 537310.
29. Parashar UD, Hummelman EG, Bresee JS, et al. (2003) Global illness and deaths caused by rotavirus disease in children. Emerg Infect Dis 9, 565-572.
30. Reeves PG, Nielsen FH & Fahey GC (1993) AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123, 1939-1951.
31. Pérez-Cano FJ, Marín-Gallén S, Castell M, et al. (2007) Bovine whey protein concentrate supplementation modulates maturation of immune system in suckling rats. Br J Nutr 98, S80-S84.
32. Etzold S & Bode L (2014) Glycan-dependent viral infection in infants and the role of human milk oligosaccharides. Curr Opin Virol 7, 101-107.
33. Westerbeek E, Hensgens R, Mihatsch W, et al. (2011) The effect of neutral and acidic oligosaccharides on stool viscosity, stool frequency and stool pH in preterm infants. Acta Paediatr 100, 1426-1431.
34. Rigo-Adrover M, Saldaña-Ruíz S, van Limpt K, et al. (2016) A combination of scGOS/lcFOS with Bifidobacterium breve M-16V protects suckling rats from rotavirus gastroenteritis. Eur J Nutr (epublication ahead of print version 25 April 2016).
35. Desselberger U & Huppertz HI (2011) Immune responses to rotavirus infection and vaccination and associated correlates of protection. J Infect Dis 203, 188-195.
36. Greenberg HB & Estes MK (2009) Rotaviruses: from pathogenesis to vaccination. Gastroenterology 136, 1939-1951.
37. Riechmann ER, Cilleruelo ML & Rivero MJ (2006) Infección por rotavirus en España (Rotavirus infection in Spain). In Infección por rotavirus (Rotavirus Infection), pp. 67-75 [ER Riechmann, editor]. Madrid: Undergraf S.L.