Bovine whey protein concentrate supplementation modulates maturation of immune system in suckling rats

British Journal of Nutrition

Volumn 98, Issue SUPPL. 1, 2007, Pages

  Pérez Cano, Francisco J ^a   Marín Galén, Silvia ^a   Castell, Margarida ^a   Rodríguez Palmero, María ^b   Rivero, Montserrat ^b   Franch, Àngels ^a   Castellote, Cristina ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Laboratorios Ordesa   (Spain)

Author keywords

Intraepithelial lymphocytes; Lamina propria lymphocytes; Milk; Rat; Suckling; Whey

Indexed keywords

CD8ALPHA ALPHA ANTIGEN; CD8ALPHA ANTIGEN; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MILK PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTIFICIAL MILK; CD8+ T LYMPHOCYTE; CELL FUNCTION; CONFERENCE PAPER; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; FLOW CYTOMETRY; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; IMMUNOMODULATION; INFANT NUTRITION; INTESTINE CELL; MUCOSAL IMMUNITY; NATURAL KILLER CELL; NEWBORN; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; WHEY;

AGING; ANIMAL NUTRITION PHYSIOLOGY; ANIMALS; ANIMALS, NEWBORN; ANIMALS, SUCKLING; CATTLE; DIETARY SUPPLEMENTS; GROWTH; IMMUNITY, MUCOSAL; IMMUNOGLOBULINS; INTESTINAL MUCOSA; INTESTINE, SMALL; LYMPHOCYTE SUBSETS; MILK PROTEINS; RATS; RATS, WISTAR;

ANIMALIA; BOVINAE; RATTUS; RATTUS NORVEGICUS;

EID: 35148857987     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114507838074     Document Type: Conference Paper

References (19)

1. Walker WA (2002) Development of the intestinal mucosal barrier. J Pediatr Gastroenterol Nutr 34, S33-S39.
2. Mowat AM (2003) Anatomical basis of tolerance and immunity to intestinal antigens. Nat Rev Immunol 3, 331-341.
3. Pérez-Cano FJ, Castellote C, Marín-Gallén S, Franch A & Castell M (2005) Neonatal immunoglobulin secretion and lymphocyte phenotype in rat small intestine lamina propria. Pediatr Res 58, 164-169.
4. Pérez-Cano FJ, Castellote C, González-Castro A, Pelegrí C, Castell M & Franch A (2005) Developmental changes in intraepithelial T lymphocytes and NK cells in the small intestine of neonatal rats. Pediatr Res 58, 885-891.
5. DeWitt RC & Kudsk KA (1999) The gut's role in metabolism, mucosal barrier function, and gut immunology. Infect Dis Clin North Am 13, 465-481.
6. Lönnerdal B (2000) Breast milk: A truly functional food. Nutrition 16, 509-511.
7. Hanson LA, Korotkova M & Telemo E (2005) Human milk: Its components and their immubiologic functions. In Mucosal Immunology, 3rd ed., vol.1, pp.1795-1827 (J Mestecky, J Bienenstock, M, Lamm, W Strober, J McGhee and LI Mayer, editors]. Amsterdam: Elsevier Academic Press.
8. Gill HS, Doull F, Rutherfurd KJ & Cross ML (2000) Immunoregulatory peptides in bovine milk. Br J Nutr 84, S111-S117.
9. Uruakpa FO, Ismond MAH & Akobondu ENT (2002) Colostrum and its benefits: a review. Nutr Res 22, 755-767.
10. Kelleher SL & Lonnerdal B (2001) Immunological activities associated with milk. Adv Nutr Res 10, 39-65.
11. Pérez-Cano FJ, González-Castro AM, Marín-Gallén S, Castellote C, Franch A & Castell M (2007) Phenotypic and functional characteristics of rat spleen lymphocytes during suckling. Dev Comp Immunol 9, [Epub ahead of print].
12. Ramiro-Puig E, Pérez-Cano FJ, Ramírez-Santana C, Castellote C, Izquierdo-Pulido M, Permanyer J, Franch A & Castell M (2007) Spleen - lymphocyte function modulated by cocoa-enriched diet. Clin Exp Immunol 12, [Epub ahead of print].
13. Todd DJ, Greiner DL, Rossini AA, Mordes JP & Bortell R (1999) An atypical population of NK cells that spontaneously secrete IFN-γ and IL-4 is present in the intraepithelial lymphoid compartment of the rat. J Immunol 167, 3600-3609.
14. Xu LB, Chen L, Gao W & Du KH (2006) Bovine immune colostrum against 17 strains of diarrhea bacteria and in vitro and in vivo effects of its specific IgG. Vaccine 24, 2131-2140.
15. Sekine K, Ushida Y, Kuhara T, et al. (1997) Inhibition of initiation and early stage development of aberrant crypt foci and enhanced natural killer activity in male rats administered bovine lactoferrin concomitantly with azoxymethane. Cancer Lett 121 211-216.
16. Wang WP, Iigo M, Sato J, Sekine K, Adachi I & Tsuda H (2000) Activation of intestinal mucosal immunity in tumor-bearing mice by lactoferrin. Jpn J Cancer Res 91, 1022-1027.
17. Hayday A, Theodoridis E, Ramsburg E & Shires J (2001) Intraepithelial lymphocytes: Exploring the Third Way in immunology. Nat Immunol 2, 997-1003.
18. Florén CH, Chinenye S, Elfstrand L, Hagman C & Ihse I (2006) ColoPlus, a new product based on bovine colostrum, alleviates HIV-associated diarrhoea. Scand J Gastroenterol 41, 682-686.
19. Wong CW & Watson DL (1995) Immunomodulatory effects of dietary whey proteins in mice. J Dairy Res 62, 359-368.