-
1
-
-
1442311053
-
Phenothiazines suppress proliferation and induce apoptosis in cultured leukemic cells without any influence on the viability of normal lymphocytes
-
Zhelev Z, Ohba H, Bakalova R, Hadjimitova V, Ishikawa M, Shinohara Y and Baba Y: Phenothiazines suppress proliferation and induce apoptosis in cultured leukemic cells without any influence on the viability of normal lymphocytes. Phenothiazines and leukemia. Cancer Chemother Pharmacol 53: 267-275, 2004.
-
(2004)
Phenothiazines and Leukemia. Cancer Chemother Pharmacol
, vol.53
, pp. 267-275
-
-
Zhelev, Z.1
Ohba, H.2
Bakalova, R.3
Hadjimitova, V.4
Ishikawa, M.5
Shinohara, Y.6
Baba, Y.7
-
2
-
-
84896748716
-
Antipsychotic agent thioridazine sensitizes renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen speciesmediated inhibition of Akt signaling and downregulation of Mcl-1 and c-FLIP(L)
-
Min KJ, Seo BR, Bae YC, Yoo YH and Kwon TK: Antipsychotic agent thioridazine sensitizes renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen speciesmediated inhibition of Akt signaling and downregulation of Mcl-1 and c-FLIP(L). Cell Death Dis 5: e1063, 2014.
-
(2014)
Cell Death Dis
, vol.5
, pp. e1063
-
-
Min, K.J.1
Seo, B.R.2
Bae, Y.C.3
Yoo, Y.H.4
Kwon, T.K.5
-
3
-
-
84970937471
-
Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data
-
Cheng HW, Liang YH, Kuo YL, Chuu CP, Lin CY, Lee MH, Wu AT, Yeh CT, Chen EI, Whang-Peng J, et al: Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death Dis 6: e1753, 2015.
-
(2015)
Cell Death Dis
, vol.6
, pp. e1753
-
-
Cheng, H.W.1
Liang, Y.H.2
Kuo, Y.L.3
Chuu, C.P.4
Lin, C.Y.5
Lee, M.H.6
Wu, A.T.7
Yeh, C.T.8
Chen, E.I.9
Whang-Peng, J.10
-
4
-
-
0031807009
-
Thioridazine in the management of cancerrelated sweating
-
Cowap J and Hardy J: Thioridazine in the management of cancerrelated sweating. J Pain Symptom Manage 15: 266, 1998.
-
(1998)
J Pain Symptom Manage
, vol.15
, pp. 266
-
-
Cowap, J.1
Hardy, J.2
-
5
-
-
0036323263
-
Fever and sweats in the patient with advanced cancer
-
viii, 2002. viii
-
Zhukovsky DS: Fever and sweats in the patient with advanced cancer. Hematol Oncol Clin North Am 16: 579-588, viii, 2002. viii.
-
Hematol Oncol Clin North Am
, vol.16
, pp. 579-588
-
-
Zhukovsky, D.S.1
-
6
-
-
0036068501
-
Depression in palliative care: A systematic review. Part 2. Treatment
-
Ly KL, Chidgey J, Addington-Hall J and Hotopf M: Depression in palliative care: A systematic review. Part 2. Treatment. Palliat Med 16: 279-284, 2002.
-
(2002)
Palliat Med
, vol.16
, pp. 279-284
-
-
Ly, K.L.1
Chidgey, J.2
Addington-Hall, J.3
Hotopf, M.4
-
7
-
-
84865126692
-
Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells
-
Kang S, Dong SM, Kim BR, Park MS, Trink B, Byun HJ and Rho SB: Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells. Apoptosis 17: 989-997, 2012.
-
(2012)
Apoptosis
, vol.17
, pp. 989-997
-
-
Kang, S.1
Dong, S.M.2
Kim, B.R.3
Park, M.S.4
Trink, B.5
Byun, H.J.6
Rho, S.B.7
-
8
-
-
78649905860
-
A gene signature-based approach identifies thioridazine as an inhibitor of phosphatidylinositol-3'-kinase (PI3K)/AKT pathway in ovarian cancer cells
-
Rho SB, Kim BR and Kang S: A gene signature-based approach identifies thioridazine as an inhibitor of phosphatidylinositol-3'-kinase (PI3K)/AKT pathway in ovarian cancer cells. Gynecol Oncol 120: 121-127, 2011.
-
(2011)
Gynecol Oncol
, vol.120
, pp. 121-127
-
-
Rho, S.B.1
Kim, B.R.2
Kang, S.3
-
9
-
-
84922392505
-
Thioridazine specifically sensitizes drug-resistant cancer cells through highly increase in apoptosis and P-gp inhibition
-
Choi AR, Kim JH and Yoon S: Thioridazine specifically sensitizes drug-resistant cancer cells through highly increase in apoptosis and P-gp inhibition. Tumour Biol 35: 9831-9838, 2014.
-
(2014)
Tumour Biol
, vol.35
, pp. 9831-9838
-
-
Choi, A.R.1
Kim, J.H.2
Yoon, S.3
-
10
-
-
84934267684
-
Roles of dopamine receptors and their antagonist thioridazine in hepatoma metastasis
-
Lu M, Li J, Luo Z, Zhang S, Xue S, Wang K, Shi Y, Zhang C, Chen H and Li Z: Roles of dopamine receptors and their antagonist thioridazine in hepatoma metastasis. Onco Targets Ther 8: 1543-1552, 2015.
-
(2015)
Onco Targets Ther
, vol.8
, pp. 1543-1552
-
-
Lu, M.1
Li, J.2
Luo, Z.3
Zhang, S.4
Xue, S.5
Wang, K.6
Shi, Y.7
Zhang, C.8
Chen, H.9
Li, Z.10
-
11
-
-
84951822170
-
Mechanism of killing effect of thioridazine on human lung cancer PC9 cells
-
in Chinese
-
Gong L, Wang Y, Tong S, Liu L, Niu L, Yuan Y and Bao Y: Mechanism of killing effect of thioridazine on human lung cancer PC9 cells. Zhongguo Fei Ai Za Zhi 18: 727-733, 2015 (in Chinese).
-
(2015)
Zhongguo Fei Ai Za Zhi
, vol.18
, pp. 727-733
-
-
Gong, L.1
Wang, Y.2
Tong, S.3
Liu, L.4
Niu, L.5
Yuan, Y.6
Bao, Y.7
-
12
-
-
84935499417
-
Dopamine receptor antagonist thioridazine inhibits tumor growth in a murine breast cancer model
-
Yin T, He S, Shen G, Ye T, Guo F and Wang Y: Dopamine receptor antagonist thioridazine inhibits tumor growth in a murine breast cancer model. Mol Med Rep 12: 4103-4108, 2015.
-
(2015)
Mol Med Rep
, vol.12
, pp. 4103-4108
-
-
Yin, T.1
He, S.2
Shen, G.3
Ye, T.4
Guo, F.5
Wang, Y.6
-
13
-
-
84940517640
-
Mechanism of thioridazine plus medroxyprogesterone in the treatment of endometrial cancer
-
in Chinese
-
Meng Q, Sun X, Wang J and Wang Y: Mechanism of thioridazine plus medroxyprogesterone in the treatment of endometrial cancer. Zhonghua Yi Xue Za Zhi 95: 1540-1543, 2015 (in Chinese).
-
(2015)
Zhonghua Yi Xue Za Zhi
, vol.95
, pp. 1540-1543
-
-
Meng, Q.1
Sun, X.2
Wang, J.3
Wang, Y.4
-
14
-
-
84942120699
-
Mechanism of thioridazine-induced apoptosis of human colorectal cancer SW480 cells
-
in Chinese
-
Liu JK, Hao YJ, Huang JW, Li X, Cai HB and Peng K: Mechanism of thioridazine-induced apoptosis of human colorectal cancer SW480 cells. Nan Fang Yi Ke Da Xue Xue Bao 35: 511-515, 2015 (in Chinese).
-
(2015)
Nan Fang Yi Ke da Xue Xue Bao
, vol.35
, pp. 511-515
-
-
Liu, J.K.1
Hao, Y.J.2
Huang, J.W.3
Li, X.4
Cai, H.B.5
Peng, K.6
-
15
-
-
84861995326
-
Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells
-
Sachlos E, Risueño RM, Laronde S, Shapovalova Z, Lee JH, Russell J, Malig M, McNicol JD, Fiebig-Comyn A, Graham M, et al: Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells. Cell 149: 1284-1297, 2012.
-
(2012)
Cell
, vol.149
, pp. 1284-1297
-
-
Sachlos, E.1
Risueño, R.M.2
Laronde, S.3
Shapovalova, Z.4
Lee, J.H.5
Russell, J.6
Malig, M.7
McNicol, J.D.8
Fiebig-Comyn, A.9
Graham, M.10
-
16
-
-
84887626984
-
Co-delivery of thioridazine and doxorubicin using polymeric micelles for targeting both cancer cells and cancer stem cells
-
Ke XY, Lin Ng VW, Gao SJ, Tong YW, Hedrick JL and Yang YY: Co-delivery of thioridazine and doxorubicin using polymeric micelles for targeting both cancer cells and cancer stem cells. Biomaterials 35: 1096-1108, 2014.
-
(2014)
Biomaterials
, vol.35
, pp. 1096-1108
-
-
Ke, X.Y.1
Lin Ng, V.W.2
Gao, S.J.3
Tong, Y.W.4
Hedrick, J.L.5
Yang, Y.Y.6
-
17
-
-
60149109533
-
Looking ahead in cancer stem cell research
-
Dick JE: Looking ahead in cancer stem cell research. Nat Biotechnol 27: 44-46, 2009.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 44-46
-
-
Dick, J.E.1
-
18
-
-
0037606054
-
Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML)
-
Guan Y, Gerhard B and Hogge DE: Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML). Blood 101: 3142-3149, 2003.
-
(2003)
Blood
, vol.101
, pp. 3142-3149
-
-
Guan, Y.1
Gerhard, B.2
De, H.3
-
19
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T and Thun MJ: Cancer statistics, 2008. CA Cancer J Clin 58: 71-96, 2008.
-
(2008)
CA Cancer J Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Murray, T.6
Thun, M.J.7
-
20
-
-
84925864728
-
The anticancer effect of (1S,2S,3E,7E,11E)-3,7,11, 15-cembratetraen-17,2-olide(LS-1) through the activation of TGF-β signaling in SNU-C5/5-FU, fluorouracil-resistant human colon cancer cells
-
Kim EJ, Kang JI, Kwak JW, Jeon CH, Tung NH, Kim YH, Choi CH, Hyun JW, Koh YS, Yoo ES, et al: The anticancer effect of (1S,2S,3E,7E,11E)-3,7,11, 15-cembratetraen-17,2-olide(LS-1) through the activation of TGF-β signaling in SNU-C5/5-FU, fluorouracil-resistant human colon cancer cells. Mar Drugs 13: 1340-1359, 2015.
-
(2015)
Mar Drugs
, vol.13
, pp. 1340-1359
-
-
Kim, E.J.1
Kang, J.I.2
Kwak, J.W.3
Jeon, C.H.4
Tung, N.H.5
Kim, Y.H.6
Choi, C.H.7
Hyun, J.W.8
Koh, Y.S.9
Yoo, E.S.10
-
21
-
-
84941975795
-
Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells
-
Zhang C, Tian Y, Song F, Fu C, Han B and Wang Y: Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells. Oncol Rep 34: 2469-2476, 2015.
-
(2015)
Oncol Rep
, vol.34
, pp. 2469-2476
-
-
Zhang, C.1
Tian, Y.2
Song, F.3
Fu, C.4
Han, B.5
Wang, Y.6
-
22
-
-
0030462751
-
Inhibition of the respiration of multi-drug resistant clinical isolates of Mycobacterium tuberculosis by thioridazine: Potential use for initial therapy of freshly diagnosed tuberculosis
-
Amaral L, Kristiansen JE, Abebe LS and Millett W: Inhibition of the respiration of multi-drug resistant clinical isolates of Mycobacterium tuberculosis by thioridazine: Potential use for initial therapy of freshly diagnosed tuberculosis. J Antimicrob Chemother 38: 1049-1053, 1996.
-
(1996)
J Antimicrob Chemother
, vol.38
, pp. 1049-1053
-
-
Amaral, L.1
Kristiansen, J.E.2
Abebe, L.S.3
Millett, W.4
-
23
-
-
79959966664
-
Global clinical trials for the treatment of TB with thioridazine
-
Boeree MJ: Global clinical trials for the treatment of TB with thioridazine. Recent Pat Antiinfect Drug Discov 6: 99-103, 2011.
-
(2011)
Recent Pat Antiinfect Drug Discov
, vol.6
, pp. 99-103
-
-
Boeree, M.J.1
-
25
-
-
0022254086
-
Haloperidol and thioridazine drug levels and clinical response in schizophrenia: Comparison of gas-liquid chromatography and radioreceptor drug level assays
-
Smith RC, Baumgartner R, Burd A, Ravichandran GK and Mauldin M: Haloperidol and thioridazine drug levels and clinical response in schizophrenia: Comparison of gas-liquid chromatography and radioreceptor drug level assays. Psychopharmacol Bull 21: 52-58, 1985.
-
(1985)
Psychopharmacol Bull
, vol.21
, pp. 52-58
-
-
Smith, R.C.1
Baumgartner, R.2
Burd, A.3
Ravichandran, G.K.4
Mauldin, M.5
-
26
-
-
84898670691
-
Thioridazine, an antipsychotic drug, elicits potent antitumor effects in gastric cancer
-
Mu J, Xu H, Yang Y, Huang W, Xiao J, Li M, Tan Z, Ding Q, Zhang L, Lu J, et al: Thioridazine, an antipsychotic drug, elicits potent antitumor effects in gastric cancer. Oncol Rep 31: 2107-2114, 2014.
-
(2014)
Oncol Rep
, vol.31
, pp. 2107-2114
-
-
Mu, J.1
Xu, H.2
Yang, Y.3
Huang, W.4
Xiao, J.5
Li, M.6
Tan, Z.7
Ding, Q.8
Zhang, L.9
Lu, J.10
-
27
-
-
7444246058
-
Translationally controlled tumor protein is a target of tumor reversion
-
Tuynder M, Fiucci G, Prieur S, Lespagnol A, Géant A, Beaucourt S, Duflaut D, Besse S, Susini L, Cavarelli J, et al: Translationally controlled tumor protein is a target of tumor reversion. Proc Natl Acad Sci USA 101: 15364-15369, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15364-15369
-
-
Tuynder, M.1
Fiucci, G.2
Prieur, S.3
Lespagnol, A.4
Géant, A.5
Beaucourt, S.6
Duflaut, D.7
Besse, S.8
Susini, L.9
Cavarelli, J.10
-
28
-
-
33746046431
-
Inhibitory effect of antipsychotic drugs on the Con A-and LPS-induced proliferative activity of mouse splenocytes: A possible mechanism of action
-
Basta-Kaim A, Budziszewska B, Jagła G, Nowak W, Kubera M and Lasoń W: Inhibitory effect of antipsychotic drugs on the Con A-and LPS-induced proliferative activity of mouse splenocytes: A possible mechanism of action. J Physiol Pharmacol 57: 247-264, 2006.
-
(2006)
J Physiol Pharmacol
, vol.57
, pp. 247-264
-
-
Basta-Kaim, A.1
Budziszewska, B.2
Jagła, G.3
Nowak, W.4
Kubera, M.5
Lasoń, W.6
-
29
-
-
84904962883
-
Thioridazine inhibits angiogenesis and tumor growth by targeting the VEGFR-2/PI3K/mTOR pathway in ovarian cancer xenografts
-
Park MS, Dong SM, Kim BR, Seo SH, Kang S, Lee EJ, Lee SH and Rho SB: Thioridazine inhibits angiogenesis and tumor growth by targeting the VEGFR-2/PI3K/mTOR pathway in ovarian cancer xenografts. Oncotarget 5: 4929-4934, 2014.
-
(2014)
Oncotarget
, vol.5
, pp. 4929-4934
-
-
Park, M.S.1
Dong, S.M.2
Kim, B.R.3
Seo, S.H.4
Kang, S.5
Lee, E.J.6
Lee, S.H.7
Rho, S.B.8
-
30
-
-
0023802228
-
Thioridazine: A radiation enhancer in advanced cervical cancer
-
Hercbergs A: Thioridazine: A radiation enhancer in advanced cervical cancer? Lancet 2: 737, 1988.
-
(1988)
Lancet
, vol.2
, pp. 737
-
-
Hercbergs, A.1
-
31
-
-
84855940639
-
The role of somatostatin and dopamine D2 receptors in endocrine tumors
-
Gatto F and Hofland LJ: The role of somatostatin and dopamine D2 receptors in endocrine tumors. Endocr Relat Cancer 18: R233-R251, 2011.
-
(2011)
Endocr Relat Cancer
, vol.18
, pp. R233-R251
-
-
Gatto, F.1
Hofland, L.J.2
-
32
-
-
0022615254
-
Circumvention of multiple-drug resistance in human cancer cells by thioridazine, trifluoperazine, and chlorpromazine
-
Akiyama S, Shiraishi N, Kuratomi Y, Nakagawa M and Kuwano M: Circumvention of multiple-drug resistance in human cancer cells by thioridazine, trifluoperazine, and chlorpromazine. J Natl Cancer Inst 76: 839-844, 1986.
-
(1986)
J Natl Cancer Inst
, vol.76
, pp. 839-844
-
-
Akiyama, S.1
Shiraishi, N.2
Kuratomi, Y.3
Nakagawa, M.4
Kuwano, M.5
-
33
-
-
0027267875
-
Reversal of doxorubicin-resistance in sarcoma 180 tumor cells by inhibition of different resistance mechanisms
-
Efferth T and Volm M: Reversal of doxorubicin-resistance in sarcoma 180 tumor cells by inhibition of different resistance mechanisms. Cancer Lett 70: 197-202, 1993.
-
(1993)
Cancer Lett
, vol.70
, pp. 197-202
-
-
Efferth, T.1
Volm, M.2
-
34
-
-
84864344188
-
The dopamine D2 receptor regulates Akt and GSK-3 via Dvl-3
-
Sutton LP and Rushlow WJ: The dopamine D2 receptor regulates Akt and GSK-3 via Dvl-3. Int J Neuropsychopharmacol 15: 965-979, 2012.
-
(2012)
Int J Neuropsychopharmacol
, vol.15
, pp. 965-979
-
-
Sutton, L.P.1
Rushlow, W.J.2
-
35
-
-
34848899784
-
Synergy between verapamil and other multidrug-resistance modulators in model membranes
-
Castaing M, Loiseau A and Cornish-Bowden A: Synergy between verapamil and other multidrug-resistance modulators in model membranes. J Biosci 32: 737-746, 2007.
-
(2007)
J Biosci
, vol.32
, pp. 737-746
-
-
Castaing, M.1
Loiseau, A.2
Cornish-Bowden, A.3
|