Polyphenolic enriched extract of Cassia glauca Lamk, improves streptozotocin-induced type-1 diabetes linked with partial insulin resistance in rats

Journal of Ethnopharmacology

Volumn 198, Issue , 2017, Pages 489-498

  Veerapur, V P ^a,b   Pratap, V ^a   Thippeswamy, B S ^a,c   Marietta, P ^a   Bansal, Punit ^d   Kulkarni, P V ^a   Kulkarni, V H ^a  

^a S E T S COLLEGE OF PHARMACY   (India)

^b SREE SIDDAGANGA COLLEGE OF PHARMACY   (India)

^c Ministry of Education Saudi Arabia   (Saudi Arabia)

^d MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

Author keywords

Caesalpiniacea; Cassia glauca; Flavonoids; in vitro antioxidant; Insulin resistance; Streptozotocin; Type 1 diabetes

Indexed keywords

ALCOHOL; ALPHA GLUCOSIDASE; ANTIDIABETIC AGENT; ANTIOXIDANT; BIOLOGICAL MARKER; ETHANOL EXTRACT OF CASSIA GLAUCA; GLIBENCLAMIDE; GLUCOSE; GUM TRAGACANTH; INSULIN; ISORHOIFOLIN; LIPID; LUTEOLIN 7 GLUCOSIDE; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; POLYPHENOL DERIVATIVE; RUTOSIDE; STREPTOZOCIN; SUCROSE; UNCLASSIFIED DRUG; WATER; WATER EXTRACT OF CASSIA GLAUCA; GLUCOSE BLOOD LEVEL; POLYPHENOL;

ANIMAL EXPERIMENT; ANTIDIABETIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CASSIA; CASSIA GLAUCA; CONTROLLED STUDY; DRUG DETERMINATION; DRUG DOSE INCREASE; DRUG EFFICACY; ENZYME INHIBITION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESISTANCE; LIMIT OF QUANTITATION; LIPID ANALYSIS; LIPID BLOOD LEVEL; MALE; MEDICINAL PLANT; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; OXIDATIVE STRESS; RAT; SINGLE DRUG DOSE; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; ANIMAL; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DOSE RESPONSE; DRUG EFFECTS; GLUCOSE TOLERANCE TEST; ISOLATION AND PURIFICATION; METABOLISM; PATHOLOGY; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; CASSIA; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE TOLERANCE TEST; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; MALE; OXIDATIVE STRESS; PLANT EXTRACTS; POLYPHENOLS; RATS; RATS, WISTAR; STREPTOZOCIN;

EID: 85011672125     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2017.01.025     Document Type: Article

References (28)

1. Azevedo, M.F., Camsari, C., Sá, C.M., Lima, C.F., Fernandes-Ferreira, M., Pereira-Wilson, C., Ursolic acid and luteolin-7-glucoside improve lipid profiles and increase liver glycogen content through glycogen synthase kinase-3. Phytother. Res. 24 (2010), S220–S224.
2. Balasubashini, M.S., Rukkumani, R., Viswanathan, P., Venugopal, P.M., Ferulic acid alleviates lipid peroxidation in diabetic rats. Phytother. Res. 18 (2004), 310–314.
3. Bansal, P., Paul, P., Mudgal, J., Nayak, P.G., Pannakal, S.T., Priyadarsini, K.I., Unnikrishnan, M.K., Antidiabetic, antihyperlipidemic and antioxidant effects of the flavonoid rich fraction of Pilea microphylla (L.) in high fat diet/streptozotocin-induced diabetes in mice. Exp. Toxicol. Pathol. 64 (2012), 651–658.
4. Farswan, M., Mazumder, P.M., Parcha, V., Protective effect of Cassia glauca Linn. on the serum glucose and hepatic enzymes level in streptozotocin induced NIDDM in rats. Indian J. Pharmacol. 41:1 (2009), 19–22.
5. Gelvan, D., Saltman, P., Different cellular targets of Cu- and Fe-catalyzed oxidation observed using a Cu-compatible thiobarbiturate acid assay. Biochim. Biophys. Acta 1035 (1990), 353–360.
6. Ghosh, R., Sharatchandra, K.H., Rita, S., Thokchom, I.S., Hypoglycaemic activity of Ficus hispida (bark) in normal and diabetic rats. Indian J. Pharmacol. 36 (2004), 222–225.
7. Habbu, P.V., Mahadevan, K.M., Kulkarni, V.H., Marietta, P., Pratap, V., Thippeswamy, B.S., Veerapur, V.P., Antidiabetic activity of Argyreia speciosa (sweet) (Burm.f.)Boj. in normoglycemic and streptozotocin-induced diabetic rats. Orient Pharm. Exp. Med. 10:2 (2010), 90–102.
8. Hevener, A., Reichart, D., Janez, A., Olefsky, J., Female rats do not exhibit free fatty acid-induced insulin resistance. Diabetes 51 (2002), 1907–1912.
9. Hsu, C.Y., Shih, H.Y., Chia, Y.C., Lee, C.H., Ashida, H., Lai, Y.K., Ching-Feng, W., Rutin potentiates insulin receptor kinase to enhance insulin -dependent glucose transporter 4 translocation. Mol. Nutr. Food Res. 58 (2014), 1168–1176.
10. Kirtikar, K.R., Basu, B.D., Indian Medicinal Plants. second ed., 2, 1988, International Book distributors, Dehradun.
11. Kunchandy, E., Rao, M.N.A., Effect of curcumin on hydroxyl radical generation through Fenton reaction. Int. J. Pharm. 57 (1989), 173–176.
12. Lam, K.S., New aspects of natural products in drug discovery. Trends Microbiol. 15 (2007), 279–289.
13. Mahesh, T., Venugopal, P.M., Quercetin alleviates oxidative stress in streptozotocin-induced diabetic rats. Phytother. Res. 18 (2004), 123–127.
14. Mazumder, P.M., Farswan, M., Parcha, V., Effect of an isolated active compound (Cg-1) of Cassia glauca leaf on blood glucose, lipid profile, and atherogenic index in diabetic rats. Indian J. Pharmacol. 41:4 (2009), 182–186.
15. Naik, G.H., Priyadarsini, K.I., Naik, D.B., Gangabhagirathi, R., Mohan, H., Studies on the aqueous extract of Terminalia chebula as a potent antioxidant and a probable radioprotector. Phytomed 11 (2004), 530–538.
16. Narla, R.S., Rao, M.N.A., Scavenging of free radicals and inhibition of lipid peroxidation by 3-phenyl syndone. J. Pharm. Pharmacol. 47 (1995), 623–625.
17. Niture, N.T., Ansari, A.A., Naik, S.R., Anti-hyperglycemic activity of rutin in streptozotocin-induced diabetic rats: an effect mediated through cytokines, antioxidants and lipid biomarkers. Indian J. Exp. Biol. 52 (2014), 720–727.
18. Onkaramurthy, M., Veerapur, V.P., Thippeswamy, B.S., Madhusudana Reddy, T.N., Rayappa, H., Badami, S., Anti-diabetic and anti-cataract effects of Chromolaena odorata Linn., in streptozotocin-induced diabetic rats. J. Ethnopharmacol. 145 (2013), 363–372.
19. Papaccios, G., Pisanti, F.A., Latronico, M.V., Ammendola, E., Galdieri, M., Multiple low dose and single high dose treatments with streptozotocin do not generate nitric oxide. J. Cell Biochem. 77:1 (2000), 82–91.
20. Prabhakar, K.R., Veerapur, V.P., Parihar, V.K., Priyadarsini, K.I., Rao, B.S.S., Unnikrishnan, M.K., Evaluation and optimization of radioprotective activity of Coronopus didymus Linn. in γ-irradiated mice. Int. J. Radiat. Biol. 82 (2006), 525–536.
21. Punitha, R., Manoharan, S., Antihyperglycemic and antilipidperoxidative effects of Pongamia pinnata (Linn.) Pierre flowers in alloxan induced diabetic rats. J. Ethanopharmacol. 105 (2006), 39–46.
22. Salahuddin, M., Jalalpure, S.S., Evaluation of antidiabetic activity of Cassia glauca lam. leaf in streptozotocin induced diabetic rats. Iran. J. Pharmacol. Ther. 9:1 (2010), 29–33.
23. Unnikrishnan, M.K., Veerapur, V.P., Nayak, Y., Mudgal, P.P., Mathew, G., Antidiabetic, antihyperlipidemic and antioxidant effects of the flavonoids. Watson, R.R., Preedy, V.R., Zibadi, S., (eds.) Polyphenols in Human Health and Disease, 1, 2014, Academic Press, USA, 143–156.
24. Veerapur, V.P., Prabhakar, K.R., Thippeswamy, B.S., Bansal, P., Srinivasan, K.K., Unnikrishnan, M.K., Antidiabetic effect of Dodonaea viscosa (L). Lacq. aerial parts in high fructose-fed insulin resistant rats: a mechanism based study. Indian. J. Exp. Biol. 48:8 (2010), 800–810.
25. Veerapur, V.P., Prabhakar, K.R., Parihar, V.K., Bansal, P., Srinivasan, K.K., Priyadarsini, K.I., Unnikrishnan, M.K., Antidiabetic, hypolipidaemic and antioxidant activity of Dodonaea viscosa aerial parts in streptozotocin-induced diabetic rats. Int. J. Phytomed. 2:1 (2010), 59–70.
26. Veerapur, V.P., Prabhakar, K.R., Thippeswamy, B.S., Bansal, P., Srinivasan, K.K., Unnikrishnan, M.K., Antidiabetic effect of Ficus racemosa Linn. stem bark in high-fat diet and low-dose streptozotocin-induced type 2 diabetic rats: a mechanistic studies. Food Chem. 132:1 (2012), 186–193.
27. Verspohl, E.J., Recommended testing in diabetic research. Planta Med. 68 (2002), 581–590.
28. Vishwakarma, S.L., Rajani, M., Goyal, R.K., Comparative antidiabetic activity of different fractions of Enicostemma littorale Blume in streptozotocin induced NIDDM rats. Orient Pharm. Exp. Med. 3 (2003), 196–204.