Evaluation and optimization of radioprotective activity of Coronopus didymus Linn. in γ-irradiated mice

International Journal of Radiation Biology

Volumn 82, Issue 8, 2006, Pages 525-536

  Prabhakar, K R ^a   Veerapur, V P ^a   Parihar, K Vipan ^a   Priyadarsini, K I ^b   Rao, B S S ^c   Unnikrishnan, M K ^a  

^a MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

^b BHABHA ATOMIC RESEARCH CENTRE   (India)

^c KASTURBA MEDICAL COLLEGE   (India)

Author keywords

Coronopus didymus; Endogenous antioxidant enzymes; HPLC fingerprinting; Radioprotection; Survival studies

Indexed keywords

CORONOPUS DIDYMUS EXTRACT; HERBACEOUS AGENT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; BRASSICACEAE; CONTROLLED STUDY; GAMMA IRRADIATION; IN VIVO CULTURE; LIPID PEROXIDATION; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIATION PROTECTION;

ANIMALS; BRASSICACEAE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GAMMA RAYS; MALE; MICE; PHYTOTHERAPY; PLANT EXTRACTS; RADIATION INJURIES; RADIATION PROTECTION; RADIATION-PROTECTIVE AGENTS; SURVIVAL ANALYSIS; SURVIVAL RATE; TREATMENT OUTCOME; WHOLE-BODY IRRADIATION;

ANIMALIA; CORONOPUS DIDYMUS;

EID: 33748574533     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.1080/09553000600876686     Document Type: Article

References (38)

1. Anna-Sigrid Keck, Finley JW. 2004. Cruciferous vegetables: Cancer protective mechanisms of glucosinolate hydrolysis products and selenium. Integrative Cancer Therapies 3:5-12.
2. Arora R, Gupta D, Chawla R, Sagar R, Sharma A, Kumar R, Prasad J, Singh S, Samanta N, Sharma RK. 2005. Radioprotection by plant products: Present status and future prospects. Phytotherapy Research 19:1-22.
3. Barcellos-Hoff MH, Park C, Wright EG. 2005. Radiation and the microenvironment - tumorigenesis and therapy. Nature Reviews - Cancer 58:867 - 875.
4. Braughler JM, Chase RL, Pregenzer JF. 1987. Oxidation of ferrous iron during peroxidation of various lipid substrates. Biochimica Biophysica Acta 921:457 - 464.
5. Claiborne A. 1985. Handbook of methods for oxygen radical research. London: CRC Press.
6. Clardy J, Walsh C. 2004. Lessons from natural molecules. Nature 432:829-837.
7. De Ruiz REL, Fusco M, Sosa A, Ruiz SO. 1994. Constituents of Coronopus didymus. Fitoterpia 65:181-182.
8. Fusco MRR, De Ruiz REL, Sosa A, Ruiz OS. 2000. Isolation of sterols, oleanolic acid and flavonoids from Coronopus didymus Sm. (Brassicaceae). Acta Farmaceutica Bonaerense 19: 273-276.
9. Gelvan D, Saltman P. 1990. Different cellular targets of Cu- and Fe-catalyzed oxidation observed using a Cu-compatible thiobarbiturate acid assay. Biochimica Biophysica Acta 1035:353-360.
10. Ghosh MN. 1984. Fundamentals of experimental pharmacology, 2nd ed. Calcutta, India: Scientific Book Agency.
11. Giusti M, Raimondi M, Ravagnan G, Sapora O, Parasassi T. 1998. Human cell membrane oxidative damage induced by single and fractionated doses of ionizing radiation: A fluorescence spectroscopy study. International Journal of Radiation Biology 74:595-605.
12. Habig WH, Pabst MJ, Jarkoby WB. 1974. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. Journal of Biological Chemistry 249:7130-7139.
13. Inam ul Haque. 1989. Composition of essential oil of Coronopus didymus seeds. Journal of Chemical Society of Pakistan 11:80-81.
14. Lowry OH, Rosenhrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 193:265-275.
15. MacVittie TJ, Weiss JF, Browne D. 1996. Advances in the treatment of radiation injuries. Oxford: Pergamon Press.
16. McDowall FH, Mortan ID, McDowell AKR. 1947. Land-cress taint in cream and butter. New Zealand Journal of Science and Technology A28:305-307.
17. Mishra B, Priyadarsini KI, Sudheer Kumar M, Unnikrishnan MK. 2003. Effect of O-glycosilation on the antioxidant activity and free radical reactions of a plant flavonoid, Chrysoeriol. Bioorganic Medicinal Chemistry 11:2677-2685.
18. Misra HP, Fridovich I. 1972. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. Journal of Biological Chemistry 247:3170-3175.
19. Monig H, Messerschmidt O, Streffer C. 1990. Chemical radio-protection in mammals and in man. In: Scherer E, Streffer C, Trott K-R, editors. Radiation exposure and occupational risks. Berlin: Springer-Verlag. pp 97-143.
20. Moran A, DePierre JW, Mannervick B. 1979. Levels of glutathione, glutathione reductase, glutathione-S-transferase activities in rat liver. Biochimica Biophysica Acta 582:67-68.
21. 3+-NTA- induced kidney damage. International Congress Series 1236:481-485.
22. Onyilagha J, Bala A, Hallett R, Gruber M, Soroka J, Westcott N. 2003. Leaf flavonoids of the cruciferous species, Camelina sativa, Crambe spp., Thlaspi arvense and several other genera of the family Brassicaceae, Biochemical Systematics and Ecology 31:1309-1322.
23. Parasassi T, Giusti AM, Gratton E, Monaco E, Raimondi M, Ravagnan G, Sapora O. 1994. Evidence for an increase in water concentration in bilayers after oxidative damage of phospholipids induced by ionizing radiation. International Journal of Radiation Biology 65:329-334.
24. Paris F, Fuks Z, Kang A, Capodieci P, Juan G, Ehleiter D, Haimovitz-Friedman A, Cordon-Cadro C, Kolesnick R. 2001. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 293:293-297.
25. Prabhakar KR, Srinivasan KK, Padma GMR. 2002. Chemical investigation, anti-inflammatory and wound healing properties of Coronopus didymus. Pharmaceutical Biology 40: 490-493.
26. Prabhakar KR, Veeresh VP, Vipan Kumar P, Sudheer Kumar M, Priyadarshini KI, Rao BSS, Unnikrishnan MK. Bioactivity guided fractionation of Coronopus didymus Linn: A Free radical scavenging perspective, Phytomedicine (In press) doi: 10.1016/j.phymed.2005.07.003.
27. Priyadarshini KI, Naik DB, Moorthy PN, Mittal JP. 1995. In Proceedings of the 7th Tihany Symposium on Radiation Chemistry, p 105, Bhabha Atomic Research Center, Trombay, Mumbai, India.
28. Raskin Ribnicky DM, Komarnytsky S, Ilic N, Poulev A, Borisjuk N, Brinker A, Moreno DA, Ripoll C, Fridlender B. 2002. Plants and human health in the twenty-first century. TRENDS in Biotechnology 20:522-532.
29. Robert JW, Spencer JPE, Rice-Evans C. 2004. Serial review: Flavonoids and isoflavones (phytoestrogens): Absorption, metabolism, and bioactivity. Free Radical Biology and Medicine 36:838-849.
30. Sedlak J, Lindsay R. 1968. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Analytical Biochemistry 25:192-205.
31. Springfield EP, Eagles PKF, Scott G. 2005. Quality assessment of South African herbal medicines by means of HPLC finger-printing. Journal of Ethnopharmacology 101:75-83.
32. Tannehill SP, Mehta MP. 1996. Amifostine and radiation therapy: Past, present, and future. Seminars in Oncology 23(Suppl. 8):69-77.
33. Uma Devi P. 1998. Normal tissue protection in cancer therapy: Progress and prospects. Acta Oncologica 37:247-252.
34. Uma Devi P, Ganasoundari A, Rao BSS, Srinivasan KK. 1999. In vivo radioprotection by ocimum flavanoids: Survival of mice. Radiation Research 151:74-78.
35. Verhoeven DT, Goldbohm RA, Van Poppel G. 1996. Epidemiological studies on Brassica vegetables and cancer risk. Cancer Epidemiology Biomarkers & Prevention 5:733-748.
36. Weiss JF, Landauer MR. 2003. Protection against ionizing radiation by antioxidant nutrients and phytochemicals. Toxicology 189:1-20.
37. Weiss JF. 1997. Pharmacological approaches to protection against radiation-induced lethality and other damage. Environmental Health Perspective 105(Suppl. 6):1473-1478.
38. Willson RL. 1983. Free radical repair mechanisms and the interaction of glutathione, Vit C and Vit E. In: Nygaard OF, Simic MG, editors. Radioprotectors and anticarcinogens. New York: Academic Press. pp 1-22.