Low-density granulocytes: Functionally distinct, immature neutrophils in rheumatoid arthritis with altered properties and defective TNF signalling

Journal of Leukocyte Biology

Volumn 101, Issue 2, 2017, Pages 599-611

  Wright, Helen L ^a   Makki, Fatima A ^a   Moots, Robert J ^b   Edwards, Steven W ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY HOSPITAL AINTREE   (United Kingdom)

Author keywords

Apoptosis; Cell cycle; LDGs; NETs; RNA Seq

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYTOKINE; CYTOKINE RECEPTOR; MYELOPEROXIDASE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTOME; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR;

ADULT; AGED; APOPTOSIS; APOPTOSIS ASSAY; ARTICLE; CELL CYCLE ASSAY; CHEMOTAXIS; CHEMOTAXIS ASSAY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXTRACELLULAR TRAP; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GRANULOCYTE; HUMAN; HUMAN CELL; MALE; NEUTROPHIL; PHAGOCYTOSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RHEUMATOID ARTHRITIS; RNA SEQUENCE; S PHASE CELL CYCLE CHECKPOINT; SIGNAL TRANSDUCTION; BLOOD; CELL CYCLE; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; SEQUENCE ANALYSIS; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; APOPTOSIS; ARTHRITIS, RHEUMATOID; CELL CYCLE; CHEMOTAXIS; CYTOKINES; EXTRACELLULAR TRAPS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MALE; MIDDLE AGED; NEUTROPHILS; PHAGOCYTOSIS; REACTIVE OXYGEN SPECIES; RECEPTORS, TUMOR NECROSIS FACTOR; SEQUENCE ANALYSIS, RNA; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 85011382893     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.5A0116-022R     Document Type: Article

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