Estimating and accounting for tumor purity in the analysis of DNA methylation data from cancer studies

Genome Biology

Volumn 18, Issue 1, 2017, Pages

  Zheng, Xiaoqi ^a   Zhang, Naiqian ^b   Wu, Hua Jun ^c   Wu, Hao ^d  

^a SHANGHAI NORMAL UNIVERSITY   (China)

^b WEIFANG UNIVERSITY   (China)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d EMORY UNIVERSITY   (United States)

Author keywords

Cancer epigenomics; Differential methylation; DNA methylation; Tumor purity

Indexed keywords

ARTICLE; CANCER CLASSIFICATION; CONTROLLED STUDY; DATA ANALYSIS; DNA METHYLATION; DNA MICROARRAY; INTERMETHOD COMPARISON; MALIGNANT NEOPLASM; MATHEMATICAL MODEL; MEASUREMENT ACCURACY; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY ANALYSIS; STATISTICAL ANALYSIS; ALGORITHM; CLUSTER ANALYSIS; COMPUTER SIMULATION; CPG ISLAND; EPIGENETICS; GENETIC EPIGENESIS; GENETICS; HUMAN; NEOPLASM; PROCEDURES;

ALGORITHMS; CLUSTER ANALYSIS; COMPUTER SIMULATION; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; EPIGENOMICS; HUMANS; NEOPLASMS; ROC CURVE;

EID: 85010962092     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-016-1143-5     Document Type: Article

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