Inhibition of monoamine oxidase-B by selegiline reduces cigarette smoke-induced oxidative stress and inflammation in airway epithelial cells

Toxicology Letters

Volumn 268, Issue , 2017, Pages 44-50

  Cui, Yuting ^a   Liu, Kenneth W K ^a   Liang, Yingmin ^a   Ip, Mary S M ^a   Mak, Judith C W ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Airway epithelium; Cigarette smoke medium; Inflammation; Monoamine oxidase; Oxidative stress; Selegiline

Indexed keywords

ACETYLCYSTEINE; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; BTB AND CNC HOMOLOG 1; CATALASE; CIGARETTE SMOKE; CYTOPLASM PROTEIN; GLUTATHIONE; GLUTATHIONE DISULFIDE; HEME OXYGENASE 1; I KAPPA B KINASE; INTERLEUKIN 8; NAD(P)H QUINONE DEHYDROGENASE 1; NITRATE REDUCTASE [NAD(P)H]; OXIDOREDUCTASE; REACTIVE OXYGEN METABOLITE; REGULATOR PROTEIN; SELEGILINE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; AMINE OXIDASE (FLAVIN CONTAINING); ANTIINFLAMMATORY AGENT; ANTIOXIDANT; AUTACOID; IL8 PROTEIN, HUMAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MONOAMINE OXIDASE INHIBITOR; SMOKE;

AIRWAY EPITHELIUM CELL; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOSOL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY TRACT INFLAMMATION; SIGNAL TRANSDUCTION; SMOKING; TRANSCRIPTION INITIATION; ADVERSE EFFECTS; BRONCHUS; CELL LINE; CELL PROTECTION; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; EPITHELIUM CELL; METABOLISM; PATHOLOGY; PNEUMONIA; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SMOKE;

ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; BRONCHI; CELL LINE; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-8; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; NF-KAPPA B; OXIDATIVE STRESS; PNEUMONIA; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; REACTIVE OXYGEN SPECIES; SELEGILINE; SIGNAL TRANSDUCTION; SMOKE; SMOKING;

EID: 85010903949     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2017.01.005     Document Type: Article

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