Nicotine reverses hypofrontality in animal models of addiction and schizophrenia

Nature Medicine

Volumn 23, Issue 3, 2017, Pages 347-354

  Koukouli, Fani ^a,b   Rooy, Marie ^c   Tziotis, Dimitrios ^b   Sailor, Kurt A ^a,b   O'Neill, Heidi C ^d   Levenga, Josien ^d   Witte, Mirko ^e   Nilges, Michael ^b   Changeux, Jean Pierre ^b   Hoeffer, Charles A ^d   Stitzel, Jerry A ^d   Gutkin, Boris S ^c,f   Digregorio, David A ^a,b   Maskos, Uwe ^a,b  

^a INSTITUT PASTEUR   (France)

^b CNRS   (France)

^c ECOLE NORMALE SUPÉRIEURE   (France)

^d UNIVERSITY OF COLORADO   (United States)

^e UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^f NATIONAL RESEARCH UNIVERSITY HIGHER SCHOOL OF ECONOMICS   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; NICOTINE; SOMATOSTATIN; VASOACTIVE INTESTINAL POLYPEPTIDE; BETA 2 ADRENERGIC RECEPTOR; BUNGAROTOXIN RECEPTOR; CHRNA5 PROTEIN, MOUSE; CHRNA7 PROTEIN, MOUSE; NICOTINIC AGENT; NICOTINIC RECEPTOR;

ADDICTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVITY; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; INTERNEURON; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SCHIZOPHRENIA; SENSORY GATING; SINGLE NUCLEOTIDE POLYMORPHISM; SOCIAL INTERACTION; WAKEFULNESS; ANIMAL; ANIMAL BEHAVIOR; CRISPR CAS SYSTEM; DISEASE MODEL; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; KNOCKOUT MOUSE; NERVE CELL INHIBITION; PATHOPHYSIOLOGY; PREFRONTAL CORTEX; PREPULSE INHIBITION; SOCIAL BEHAVIOR; STARTLE REFLEX; TOBACCO DEPENDENCE; TRANSGENIC MOUSE;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANIMALS; BEHAVIOR, ANIMAL; CRISPR-CAS SYSTEMS; DISEASE MODELS, ANIMAL; FLUORESCENT ANTIBODY TECHNIQUE; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NEURAL INHIBITION; NICOTINE; NICOTINIC AGONISTS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREFRONTAL CORTEX; PREPULSE INHIBITION; PYRAMIDAL CELLS; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, NICOTINIC; REFLEX, STARTLE; SCHIZOPHRENIA; SOCIAL BEHAVIOR; TOBACCO USE DISORDER;

EID: 85010894766     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4274     Document Type: Article

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