-
1
-
-
0032568534
-
Alpha-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies
-
[1] Spillantini, M.G., Crowther, R.A., Jakes, R., Hasegawa, M., Goedert, M., Alpha-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proc. Natl. Acad. Sci. U.S.A. 95 (1998), 6469–6473.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
2
-
-
0036174010
-
Alpha-synuclein is phosphorylated in synucleinopathy lesions
-
[2] Fujiwara, H., Hasegawa, M., Dohmae, N., Kawashima, A., Masliah, E., Goldberg, M.S., et al. Alpha-synuclein is phosphorylated in synucleinopathy lesions. Nat. Cell Biol. 4 (2002), 160–164.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 160-164
-
-
Fujiwara, H.1
Hasegawa, M.2
Dohmae, N.3
Kawashima, A.4
Masliah, E.5
Goldberg, M.S.6
-
3
-
-
33749570292
-
Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease
-
[3] Anderson, J.P., Walker, D.E., Goldstein, J.M., de Laat, R., Banducci, K., Caccavello, R.J., et al. Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease. J. Biol. Chem. 281 (2006), 29739–29752.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 29739-29752
-
-
Anderson, J.P.1
Walker, D.E.2
Goldstein, J.M.3
de Laat, R.4
Banducci, K.5
Caccavello, R.J.6
-
4
-
-
77953021942
-
Multi-organ distribution of phosphorylated alpha-synuclein histopathology in subjects with Lewy body disorders
-
[4] Beach, T.G., Adler, C.H., Sue, L.I., Vedders, L., Lue, L., White Iii, C.L., et al. Multi-organ distribution of phosphorylated alpha-synuclein histopathology in subjects with Lewy body disorders. Acta Neuropathol. 119 (2010), 689–702.
-
(2010)
Acta Neuropathol.
, vol.119
, pp. 689-702
-
-
Beach, T.G.1
Adler, C.H.2
Sue, L.I.3
Vedders, L.4
Lue, L.5
White Iii, C.L.6
-
5
-
-
84994113227
-
Multicenter assessment of immunohistochemical methods for pathological alpha-Synuclein in sigmoid colon of autopsied parkinson's disease and control subjects
-
[5] Beach, T.G., Corbillé, A.-G., Letournel, F., Kordower, J.H., Kremer, T., Munoz, D.G., et al. Multicenter assessment of immunohistochemical methods for pathological alpha-Synuclein in sigmoid colon of autopsied parkinson's disease and control subjects. J. Parkinson's Dis. 6 (2016), 761–770.
-
(2016)
J. Parkinson's Dis.
, vol.6
, pp. 761-770
-
-
Beach, T.G.1
Corbillé, A.-G.2
Letournel, F.3
Kordower, J.H.4
Kremer, T.5
Munoz, D.G.6
-
6
-
-
56549121613
-
Pathological lesions in colonic biopsies during Parkinson's disease
-
[6] Lebouvier, T., Chaumette, T., Damier, P., Coron, E., Touchefeu, Y., Vrignaud, S., et al. Pathological lesions in colonic biopsies during Parkinson's disease. Gut 57 (2008), 1741–1743, 10.1136/gut.2008.162503.
-
(2008)
Gut
, vol.57
, pp. 1741-1743
-
-
Lebouvier, T.1
Chaumette, T.2
Damier, P.3
Coron, E.4
Touchefeu, Y.5
Vrignaud, S.6
-
7
-
-
77958558412
-
Colonic biopsies to assess the neuropathology of Parkinson's disease and its relationship with symptoms
-
[7] Lebouvier, T., Neunlist, M., Bruley des Varannes, S., Coron, E., Drouard, A., Nguyen, J.-M., et al. Colonic biopsies to assess the neuropathology of Parkinson's disease and its relationship with symptoms. PLoS One, 5, 2010, e12728.
-
(2010)
PLoS One
, vol.5
, pp. e12728
-
-
Lebouvier, T.1
Neunlist, M.2
Bruley des Varannes, S.3
Coron, E.4
Drouard, A.5
Nguyen, J.-M.6
-
8
-
-
81955167987
-
A comparison between rectal and colonic biopsies to detect Lewy pathology in Parkinson's disease
-
[8] Pouclet, H., Lebouvier, T., Coron, E., des Varannes, S.B., Rouaud, T., Roy, M., et al. A comparison between rectal and colonic biopsies to detect Lewy pathology in Parkinson's disease. Neurobiol. Dis. 45 (2012), 305–309.
-
(2012)
Neurobiol. Dis.
, vol.45
, pp. 305-309
-
-
Pouclet, H.1
Lebouvier, T.2
Coron, E.3
des Varannes, S.B.4
Rouaud, T.5
Roy, M.6
-
9
-
-
84923536410
-
Colonic mucosal α-synuclein lacks specificity as a biomarker for Parkinson disease
-
[9] Visanji, N.P., Marras, C., Kern, D.S., Al Dakheel, A., Gao, A., Liu, L.W.C., et al. Colonic mucosal α-synuclein lacks specificity as a biomarker for Parkinson disease. Neurology 84 (2015), 609–616.
-
(2015)
Neurology
, vol.84
, pp. 609-616
-
-
Visanji, N.P.1
Marras, C.2
Kern, D.S.3
Al Dakheel, A.4
Gao, A.5
Liu, L.W.C.6
-
10
-
-
84861692236
-
Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease
-
[10] Shannon, K.M., Keshavarzian, A., Mutlu, E., Dodiya, H.B., Daian, D., Jaglin, J.A., et al. Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease. Mov. Disord. 27 (2012), 709–715.
-
(2012)
Mov. Disord.
, vol.27
, pp. 709-715
-
-
Shannon, K.M.1
Keshavarzian, A.2
Mutlu, E.3
Dodiya, H.B.4
Daian, D.5
Jaglin, J.A.6
-
11
-
-
84896717250
-
Accumulation of α-synuclein in the bowel of patients in the pre-clinical phase of Parkinson's disease
-
[11] Hilton, D., Stephens, M., Kirk, L., Edwards, P., Potter, R., Zajicek, J., et al. Accumulation of α-synuclein in the bowel of patients in the pre-clinical phase of Parkinson's disease. Acta Neuropathol. 127 (2013), 235–241.
-
(2013)
Acta Neuropathol.
, vol.127
, pp. 235-241
-
-
Hilton, D.1
Stephens, M.2
Kirk, L.3
Edwards, P.4
Potter, R.5
Zajicek, J.6
-
12
-
-
84994094890
-
Evaluation of alpha-synuclein immunohistochemical methods for the detection of Lewy-type synucleinopathy in gastrointestinal biopsies
-
[12] Corbillé, A.-G., Letournel, F., Kordower, J.H., Lee, J., Shanes, E., Neunlist, M., et al. Evaluation of alpha-synuclein immunohistochemical methods for the detection of Lewy-type synucleinopathy in gastrointestinal biopsies. Acta Neuropathol. Commun., 4, 2016, 35.
-
(2016)
Acta Neuropathol. Commun.
, vol.4
, pp. 35
-
-
Corbillé, A.-G.1
Letournel, F.2
Kordower, J.H.3
Lee, J.4
Shanes, E.5
Neunlist, M.6
-
13
-
-
84952668206
-
Optimizing western blots for the detection of endogenous α-synuclein in the enteric nervous system
-
[13] Preterre, C., Corbillé, A.-G., Balloy, G., Letournel, F., Neunlist, M., Derkinderen, P., Optimizing western blots for the detection of endogenous α-synuclein in the enteric nervous system. J, Parkinson's Dis. 5 (2015), 765–772.
-
(2015)
J, Parkinson's Dis.
, vol.5
, pp. 765-772
-
-
Preterre, C.1
Corbillé, A.-G.2
Balloy, G.3
Letournel, F.4
Neunlist, M.5
Derkinderen, P.6
-
14
-
-
84894257100
-
A new method for quantitative immunoblotting of endogenous α-synuclein
-
[14] Newman, A.J., Selkoe, D., Dettmer, U., A new method for quantitative immunoblotting of endogenous α-synuclein. PLoS One, 8, 2013, e81314.
-
(2013)
PLoS One
, vol.8
, pp. e81314
-
-
Newman, A.J.1
Selkoe, D.2
Dettmer, U.3
-
15
-
-
0036669811
-
Platelet alpha- and gamma-synucleins in Parkinson's disease and normal control subjects
-
[15] Li, Q.-X., Campbell, B.C.V., McLean, C.A., Thyagarajan, D., Gai, W.P., Kapsa, R.M., et al. Platelet alpha- and gamma-synucleins in Parkinson's disease and normal control subjects. J. Alzheimers Dis. 4 (2002), 309–315.
-
(2002)
J. Alzheimers Dis.
, vol.4
, pp. 309-315
-
-
Li, Q.-X.1
Campbell, B.C.V.2
McLean, C.A.3
Thyagarajan, D.4
Gai, W.P.5
Kapsa, R.M.6
-
16
-
-
0034674376
-
Full length alpha-synuclein is present in cerebrospinal fluid from Parkinson's disease and normal subjects
-
[16] Borghi, R., Marchese, R., Negro, A., Marinelli, L., Forloni, G., Zaccheo, D., et al. Full length alpha-synuclein is present in cerebrospinal fluid from Parkinson's disease and normal subjects. Neurosci. Lett. 287 (2000), 65–67.
-
(2000)
Neurosci. Lett.
, vol.287
, pp. 65-67
-
-
Borghi, R.1
Marchese, R.2
Negro, A.3
Marinelli, L.4
Forloni, G.5
Zaccheo, D.6
-
17
-
-
84983688506
-
Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein
-
[17] Wang, W., Nguyen, L.T.T., Burlak, C., Chegini, F., Guo, F., Chataway, T., et al. Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein. Proc. Natl. Acad. Sci. U. S. A. 113 (2016), 9587–9592.
-
(2016)
Proc. Natl. Acad. Sci. U. S. A.
, vol.113
, pp. 9587-9592
-
-
Wang, W.1
Nguyen, L.T.T.2
Burlak, C.3
Chegini, F.4
Guo, F.5
Chataway, T.6
-
18
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
[18] Braak, H., Del Tredici, K., Rüb, U., de Vos, R.A.I., Jansen Steur, E.N.H., Braak, E., Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol. Aging 24 (2003), 197–211.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rüb, U.3
de Vos, R.A.I.4
Jansen Steur, E.N.H.5
Braak, E.6
-
19
-
-
32544442518
-
Gastric alpha-synuclein immunoreactive inclusions in Meissner's and Auerbach‘s plexuses in cases staged for Parkinson's disease-related brain pathology
-
[19] Braak, H., de Vos, R.A.I., Bohl, J., Del Tredici, K., Gastric alpha-synuclein immunoreactive inclusions in Meissner's and Auerbach‘s plexuses in cases staged for Parkinson's disease-related brain pathology. Neurosci. Lett. 396 (2006), 67–72.
-
(2006)
Neurosci. Lett.
, vol.396
, pp. 67-72
-
-
Braak, H.1
de Vos, R.A.I.2
Bohl, J.3
Del Tredici, K.4
-
20
-
-
84994614108
-
Potential pathways of abnormal tau and α-synuclein dissemination in sporadic alzheimers and parkinsons diseases
-
[20] Braak, H., Del Tredici, K., Potential pathways of abnormal tau and α-synuclein dissemination in sporadic alzheimers and parkinsons diseases. Cold Spring Harb. Perspect. Biol., 8, 2016, a023630, 10.1101/cshperspect.a023630.
-
(2016)
Cold Spring Harb. Perspect. Biol.
, vol.8
, pp. a023630
-
-
Braak, H.1
Del Tredici, K.2
-
21
-
-
84973345168
-
How strong is the evidence that Parkinson's disease is a prion disorder?
-
[21] Brundin, P., Ma, J., Kordower, J.H., How strong is the evidence that Parkinson's disease is a prion disorder?. Curr. Opin. Neurol. 29 (2016), 459–466.
-
(2016)
Curr. Opin. Neurol.
, vol.29
, pp. 459-466
-
-
Brundin, P.1
Ma, J.2
Kordower, J.H.3
-
22
-
-
84922092995
-
Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats
-
[22] Holmqvist, S., Chutna, O., Bousset, L., Aldrin-Kirk, P., Li, W., Björklund, T., et al. Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats. Acta Neuropathol. 128 (2014), 805–820.
-
(2014)
Acta Neuropathol.
, vol.128
, pp. 805-820
-
-
Holmqvist, S.1
Chutna, O.2
Bousset, L.3
Aldrin-Kirk, P.4
Li, W.5
Björklund, T.6
-
23
-
-
84984787903
-
Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson's disease
-
[23] Rey, N.L., Steiner, J.A., Maroof, N., Luk, K.C., Madaj, Z., Trojanowski, J.Q., et al. Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson's disease. J. Exp. Med. 213 (2016), 1759–17784.
-
(2016)
J. Exp. Med.
, vol.213
, pp. 1759-17784
-
-
Rey, N.L.1
Steiner, J.A.2
Maroof, N.3
Luk, K.C.4
Madaj, Z.5
Trojanowski, J.Q.6
-
24
-
-
81955161348
-
Biopsable neural tissues: toward new biomarkers for Parkinson's disease?
-
[24] Lebouvier, T., Tasselli, M., Paillusson, S., Pouclet, H., Neunlist, M., Derkinderen, P., Biopsable neural tissues: toward new biomarkers for Parkinson's disease?. Front. Psychiatry, 1, 2010, 128.
-
(2010)
Front. Psychiatry
, vol.1
, pp. 128
-
-
Lebouvier, T.1
Tasselli, M.2
Paillusson, S.3
Pouclet, H.4
Neunlist, M.5
Derkinderen, P.6
-
25
-
-
85016824623
-
The search for a peripheral biopsy indicator of α-Synuclein pathology for parkinson disease
-
[25] Lee, J.M., Derkinderen, P., Kordower, J.H., Freeman, R., Munoz, D.G., Kremer, T., et al. The search for a peripheral biopsy indicator of α-Synuclein pathology for parkinson disease. J. Neuropathol. Exp. Neurol., 2017, nlw103, 10.1093/jnen/nlw103.
-
(2017)
J. Neuropathol. Exp. Neurol.
, pp. nlw103
-
-
Lee, J.M.1
Derkinderen, P.2
Kordower, J.H.3
Freeman, R.4
Munoz, D.G.5
Kremer, T.6
-
26
-
-
0032763540
-
The expression of alpha- beta-, and gamma-synucleins in olfactory mucosa from patients with and without neurodegenerative diseases
-
[26] Duda, J.E., Shah, U., Arnold, S.E., Lee, V.M., Trojanowski, J.Q., The expression of alpha- beta-, and gamma-synucleins in olfactory mucosa from patients with and without neurodegenerative diseases. Exp. Neurol. 160 (1999), 515–522.
-
(1999)
Exp. Neurol.
, vol.160
, pp. 515-522
-
-
Duda, J.E.1
Shah, U.2
Arnold, S.E.3
Lee, V.M.4
Trojanowski, J.Q.5
-
27
-
-
77951723978
-
Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease
-
[27] Arnold, S.E., Lee, E.B., Moberg, P.J., Stutzbach, L., Kazi, H., Han, L.-Y., et al. Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease. Ann. Neurol. 67 (2010), 462–469.
-
(2010)
Ann. Neurol.
, vol.67
, pp. 462-469
-
-
Arnold, S.E.1
Lee, E.B.2
Moberg, P.J.3
Stutzbach, L.4
Kazi, H.5
Han, L.-Y.6
-
28
-
-
84956757922
-
Lewy body pathology involves the olfactory cells in Parkinson's disease and related disorders
-
[28] Saito, Y., Shioya, A., Sano, T., Sumikura, H., Murata, M., Murayama, S., Lewy body pathology involves the olfactory cells in Parkinson's disease and related disorders. Mov. Disord. 31 (2016), 135–138.
-
(2016)
Mov. Disord.
, vol.31
, pp. 135-138
-
-
Saito, Y.1
Shioya, A.2
Sano, T.3
Sumikura, H.4
Murata, M.5
Murayama, S.6
-
29
-
-
84873257019
-
Neuropathologic analysis of Lewy-related α-synucleinopathy in olfactory mucosa
-
[29] Funabe, S., Takao, M., Saito, Y., Hatsuta, H., Sugiyama, M., Ito, S., et al. Neuropathologic analysis of Lewy-related α-synucleinopathy in olfactory mucosa. Neuropathology 33 (2013), 47–58.
-
(2013)
Neuropathology
, vol.33
, pp. 47-58
-
-
Funabe, S.1
Takao, M.2
Saito, Y.3
Hatsuta, H.4
Sugiyama, M.5
Ito, S.6
-
30
-
-
67651160628
-
Biopsies of olfactory epithelium in patients with Parkinson's disease
-
[30] Witt, M., Bormann, K., Gudziol, V., Pehlke, K., Barth, K., Minovi, A., et al. Biopsies of olfactory epithelium in patients with Parkinson's disease. Mov. Disord. 24 (2009), 906–914.
-
(2009)
Mov. Disord.
, vol.24
, pp. 906-914
-
-
Witt, M.1
Bormann, K.2
Gudziol, V.3
Pehlke, K.4
Barth, K.5
Minovi, A.6
-
31
-
-
84977103200
-
What a gastrointestinal biopsy can tell us about Parkinson's disease
-
[31] Corbillé, A.-G., Clairembault, T., Coron, E., Leclair-Visonneau, L., Preterre, C., Neunlist, M., et al. What a gastrointestinal biopsy can tell us about Parkinson's disease. Neurogastroenterol. Motil. 28 (2016), 966–974.
-
(2016)
Neurogastroenterol. Motil.
, vol.28
, pp. 966-974
-
-
Corbillé, A.-G.1
Clairembault, T.2
Coron, E.3
Leclair-Visonneau, L.4
Preterre, C.5
Neunlist, M.6
-
32
-
-
80051855646
-
Improved immunodetection of endogenous α-synuclein
-
[32] Lee, B.R., Kamitani, T., Improved immunodetection of endogenous α-synuclein. PLoS One, 6, 2011, e23939.
-
(2011)
PLoS One
, vol.6
, pp. e23939
-
-
Lee, B.R.1
Kamitani, T.2
-
33
-
-
84865055362
-
Expression pattern and localization of alpha-synuclein in the human enteric nervous system
-
[33] Böttner, M., Zorenkov, D., Hellwig, I., Barrenschee, M., Harde, J., Fricke, T., et al. Expression pattern and localization of alpha-synuclein in the human enteric nervous system. Neurobiol. Dis. 48 (2012), 474–480.
-
(2012)
Neurobiol. Dis.
, vol.48
, pp. 474-480
-
-
Böttner, M.1
Zorenkov, D.2
Hellwig, I.3
Barrenschee, M.4
Harde, J.5
Fricke, T.6
-
34
-
-
85010887495
-
Distinct pattern of enteric phospho-alpha-synuclein aggregates and gene expression profiles in patients with Parkinson's disease
-
[34] Barrenschee, M., Zorenkov, D., Böttner, M., Lange, C., Cossais, F., Scharf, A.B., et al. Distinct pattern of enteric phospho-alpha-synuclein aggregates and gene expression profiles in patients with Parkinson's disease. Acta Neuropathol. Commun., 5, 2017, 1.
-
(2017)
Acta Neuropathol. Commun.
, vol.5
, pp. 1
-
-
Barrenschee, M.1
Zorenkov, D.2
Böttner, M.3
Lange, C.4
Cossais, F.5
Scharf, A.B.6
-
35
-
-
84858290107
-
A comparison between colonic submucosa and mucosa to detect Lewy pathology in Parkinson's disease
-
[35] Pouclet, H., Lebouvier, T., Coron, E., des Varannes, S.B., Neunlist, M., Derkinderen, P., A comparison between colonic submucosa and mucosa to detect Lewy pathology in Parkinson's disease. Neurogastroenterol. Motil. 24 (2012), e202–5.
-
(2012)
Neurogastroenterol. Motil.
, vol.24
, pp. e202-5
-
-
Pouclet, H.1
Lebouvier, T.2
Coron, E.3
des Varannes, S.B.4
Neunlist, M.5
Derkinderen, P.6
-
36
-
-
4143067071
-
Phosphorylated alpha-synuclein in normal mouse brain
-
[36] Hirai, Y., Fujita, S.C., Iwatsubo, T., Hasegawa, M., Phosphorylated alpha-synuclein in normal mouse brain. FEBS Lett. 572 (2004), 227–232.
-
(2004)
FEBS Lett.
, vol.572
, pp. 227-232
-
-
Hirai, Y.1
Fujita, S.C.2
Iwatsubo, T.3
Hasegawa, M.4
-
37
-
-
85033548081
-
Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies
-
[37] Fairfoul, G., McGuire, L.I., Pal, S., Ironside, J.W., Neumann, J., Christie, S., et al. Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies. Ann. Clin. Transl. Neurol. 3 (2016), 812–818.
-
(2016)
Ann. Clin. Transl. Neurol.
, vol.3
, pp. 812-818
-
-
Fairfoul, G.1
McGuire, L.I.2
Pal, S.3
Ironside, J.W.4
Neumann, J.5
Christie, S.6
-
38
-
-
85014678606
-
Development of a biochemical diagnosis of parkinson disease by detection of α-synuclein misfolded aggregates in cerebrospinal fluid
-
[38] Shahnawaz, M., Tokuda, T., Waragai, M., Mendez, N., Ishii, R., Trenkwalder, C., et al. Development of a biochemical diagnosis of parkinson disease by detection of α-synuclein misfolded aggregates in cerebrospinal fluid. JAMA Neurol., 2016, 10.1001/jamaneurol.2016.4547.
-
(2016)
JAMA Neurol.
-
-
Shahnawaz, M.1
Tokuda, T.2
Waragai, M.3
Mendez, N.4
Ishii, R.5
Trenkwalder, C.6
|