HIV induces expression of complement component C3 in astrocytes by NF-ΚB-dependent activation of interleukin-6 synthesis

Journal of Neuroinflammation

Volumn 14, Issue 1, 2017, Pages

  Nitkiewicz, Jadwiga ^a,c   Borjabad, Alejandra ^a   Morgello, Susan ^a   Murray, Jacinta ^a   Chao, Wei ^a   Emdad, Luni ^b   Fisher, Paul B ^b   Potash, Mary Jane ^a   Volsky, David J ^a,d  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c PSI CRO   (Poland)

^d Division of Infectious Diseases   (United States)

Author keywords

Astrocytes; Brain tissue; Complement component C3; HAND; HIV; HIV associated dementia; IL 6; Neurodegeneration; NF B

Indexed keywords

COMPLEMENT COMPONENT C3; COMPLEMENTARY RNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; PROTEIN KINASE; CAFFEIC ACID DERIVATIVE; CAFFEIC ACID PHENETHYL ESTER; ENZYME ACTIVATOR; ENZYME INHIBITOR; GLIAL FIBRILLARY ACIDIC PROTEIN; PHENETHYL ALCOHOL;

ADULT; ARTICLE; ASTROCYTE; BINDING SITE; BRAIN TISSUE; CELL NUCLEUS; COGNITIVE DEFECT; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; FEMALE; FETUS; FLUORESCENCE MICROSCOPY; GENE ACTIVATION; GENE EXPRESSION; GENE OVEREXPRESSION; HIV ASSOCIATED DEMENTIA; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN TISSUE; IMMUNOCOMPETENT CELL; MALE; MUTATIONAL ANALYSIS; NERVOUS SYSTEM INFLAMMATION; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; VIRUS INDUCTION; ANALOGS AND DERIVATIVES; DRUG EFFECTS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; VIROLOGY;

ADULT; ASTROCYTES; CAFFEIC ACIDS; COMPLEMENT C3; ENZYME ACTIVATION; ENZYME ACTIVATORS; ENZYME INHIBITORS; FEMALE; FETUS; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, VIRAL; GLIAL FIBRILLARY ACIDIC PROTEIN; HIV INFECTIONS; HUMANS; INTERLEUKIN-6; MALE; MIDDLE AGED; NF-KAPPA B; PHENYLETHYL ALCOHOL; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION;

EID: 85010450338     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-017-0794-9     Document Type: Article

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