Enhanced intracellular delivery and antibacterial efficacy of enrofloxacin-loaded docosanoic acid solid lipid nanoparticles against intracellular Salmonella

Scientific Reports

Volumn 7, Issue , 2017, Pages

  Xie, Shuyu ^a   Yang, Fei ^a   Tao, Yanfei ^a   Chen, Dongmei ^a   Qu, Wei ^a   Huang, Lingli ^a   Liu, Zhenli ^a   Pan, Yuanhu ^a   Yuan, Zonghui ^a  

^a HUAZHONG AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; BEHENIC ACID; ENROFLOXACIN; FATTY ACID; LIPID; NANOPARTICLE; QUINOLONE DERIVATIVE;

CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG EFFECT; HUMAN; MICROBIOLOGY; PATHOGENICITY; SALMONELLA; SALMONELLOSIS;

ANTI-BACTERIAL AGENTS; DRUG DELIVERY SYSTEMS; FATTY ACIDS; FLUOROQUINOLONES; HUMANS; LIPIDS; NANOPARTICLES; SALMONELLA; SALMONELLA INFECTIONS;

EID: 85010375421     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep41104     Document Type: Article

References (25)

1. Haraga, A., Ohlson, M. B., Miller, S. I. Salmonellae interplay with host cells. Nature Reviews Microbiology 6, 53-66 (2008).
2. Hale, C. R., et al. Estimates of enteric illness attributable to contact with animals and their environments in the United States. Clin. Infect. Dis. 54 (Suppl 5), S472-479 (2012).
3. Imanishi, M., et al. Salmonellosis and Meat Purchased at Live-Bird and Animal-Slaughter Markets, United States, 2007-2012. Emerg. Infect. Dis. 20(1), 167-169 (2014).
4. Lahiri, A., Iyer, N., Das, P., Chakravortty, D. Visiting the cell biology of salmonella infection. Microbes. Infect. 12, 809-818 (2010).
5. Briones, E., Colino, C. I., Lanao, J. M. Delivery systems to increase the selectivity of antibiotics in phagocytic cells. Journal of Controlled Release 125(3), 210-227 (2008).
6. Schoevers, E. J., Vanleengoed, L. A. M. G., Verheijden, J. H. M., Niewold, T. A. Effects of Enrofloxacin on Porcine Phagocytic Function. Antimicrob. Agents. Chemother. 43(9), 2138-2143 (1999).
7. Ba?, A. L., ?im?ek, A., Corlu, M., Elmas, M., De?im, Z. G. Determination of intracellular concentrations of free and two types of liposome-encapsulated enrofloxacin in Anatolian shepherd dog monocytes. J. Vet. Med. B 49, 289-293 (2002).
8. Bas, A. L., Simsek, A., Erganis, O., Corlu, M. Efficacies of liposome-encapsulated enrofloxacin against Staphylococcus aureus infection in Anatolian shepherd dog monocytes in vitro. DTW. Deutsche Tierarztliche Wochenschrift 112, 219-223 (2005).
9. De?im, Z. De?im, T., Bas, L., Elmas, M. The use of liposomal enrofloxacin for intracellular infections in Kangal dogs and visualization of phagocytosis of liposomes. Journal of biomedical materials research 61(2), 246-251 (2002).
10. Bas, A. L., et al. Efficacies of free and liposome-encapsulated enrofloxacin (Baytril? ) against Staphylococcus aureus infection in Turkish shepherd dog neutrophils in vitro. Rev. Med. Vet. 151, 415-420 (2000).
11. Akbari, V., Abedi, D., Pardakhty, A., Sadeghi-Aliabadi, H. Ciprofloxacin nano-niosomes for targeting intracellular infections: an in vitro evaluation. Journal of nanoparticle research 15(4), 1-14 (2013).
12. Chono, S., Tanino, T., Seki, T., Morimoto, K. Efficient drug delivery to alveolar macrophages and lung epithelial lining fluid following pulmonary administration of liposomal ciprofloxacin in rats with pneumonia and estimation of its antibacterial effects. Drug Dev. Ind. Pharm. 34, 1090-1096 (2008).
13. Chono, S., Tanino, T., Seki, T., Morimoto, K. Uptake characteristics of liposomes by rat alveolar macrophages: influence of particle size and surface mannose modification. J. Pharm. Pharmacol. 59, 75-80 (2007).
14. Xie, S. Y., et al. Biodegradable nanoparticles for intracellular delivery of antimicrobial agents. J. Control Release 187, 101-117 (2014).
15. Xie, S. Y., et al. Preparation, characterization and pharmacokinetics of enrofloxacin-loaded solid lipid nanoparticles: influences of fatty acids. Colloids and Surfaces B: Biointerfaces 83(2), 382-387 (2011).
16. Delsol, A. A., Woodward, M. J., Roe, J. M. Effect of a 5 day enrofloxacin treatment on Salmonella enterica serotype Typhimurium DT104 in the pig. Antimicrob. Chemother. 54, 692-693 (2004).
17. Boeckh, A., Boothe, D., Wilkie, S., Jones, S. Time Course of Enrofloxacin and Its Active Metabolite in Peripheral Leukocytes of Dogs. Vet. Ther. 2(4), 334-344 (2001).
18. Hillaireau, H., Couvreur, P. Nanocarriers' entry into the cell: relevance to drug delivery. Cell. Mol. Life Sci. 66, 2873-2896 (2009).
19. Chono, S., Tanino, T., Seki, T., K. Morimoto. Influence of particle size on drug delivery to rat alveolar macrophages following pulmonary administration of ciprofloxacin incorporated into liposomes. J. Drug Target. 14, 557-566 (2006).
20. Tabata, Y., Ikada, Y. Effect of the size and surface charge of polymer microspheres on their phagocytosis by macrophage. Biomaterials 9, 356-362 (1988).
21. Oh, Y. K., Nix, D. E., Straubinger, R. M. Formulation and efficacy of liposome-encapsulated antibiotics for therapy of intracellular Mycobacterium avium infection. Antimicrob. Agents Chemother. 392, 104-2111 (1995).
22. Schwendener, R. A., Lagocki, P. A., Rahman, Y. E. The effects of charge and size on the interaction of unilamellar liposomes with macrophages. Biochim. Biophys Acta. 772, 93-101 (1984).
23. Rigotti, A., Acton, S. L., Krieger, M. The class B scavenger receptors SR-BI and CD36 are receptors for anionic phospholipids. J. Biol. Chem. 270 16221-16224 (1995).
24. Kisich, K. O., et al. Encapsulation of moxifloxacin within poly (butyl cyanoacrylate) nanoparticles enhances efficacy against intracellular Mycobacterium tuberculosis. International Journal of Pharmaceutics, 345, 154-162 (2007).
25. Fawaz, F., Bonini, F., Maugein, J. Ciprofloxacin-loaded polyisobutylcyanoacrylate nanoparticles: pharmacokinetics and in vitro antimicrobial activity. Int. J. Pharm. 168, 255-259 (1998).