Efficacies of liposome-encapsulated enrofloxacin against Staphylococcus aureus infection in Anatolian shepherd dog monocytes in vitro

Deutsche Tierarztliche Wochenschrift

Volumn 112, Issue 6, 2005, Pages 219-223

  Bas A L ^a   Simsek A ^a   Erganis, O ^a   Corlu M ^a  

^a SELCUK UNIVERSITY   (Turkey)

Author keywords

Anatolian shepherd dog; Enrofloxacin; Liposome; Monocyte; Staphylococcus aureus

Indexed keywords

CHOLESTEROL; ENROFLOXACIN; LIPOSOME; PHOSPHATIDYLCHOLINE;

ANIMAL CELL; ARTICLE; BACTERIAL COUNT; BACTERIAL SURVIVAL; BACTERICIDAL ACTIVITY; CELL ACTIVITY; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOG; DOSE TIME EFFECT RELATION; DRUG ACTIVITY; DRUG EFFICACY; DRUG EXPOSURE; ENCAPSULATION; EVALUATION; IN VITRO STUDY; LIPID VESICLE; MALE; MEMBRANE VESICLE; MONOCYTE; NONHUMAN; PHAGOCYTE; PHAGOCYTOSIS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; STATISTICAL ANALYSIS;

ANIMALS; ANTI-INFECTIVE AGENTS; DOG DISEASES; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; FLUOROQUINOLONES; LIPOSOMES; MALE; MONOCYTES; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TREATMENT OUTCOME;

CANIS FAMILIARIS; STAPHYLOCOCCUS AUREUS;

EID: 21444453932     PISSN: 03416593     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. ANDERSON, R., JOONE, G., VAN RENSBURG, C. E. (1986): An in vitro investigation of the intracellular bioactivity of amoxicillin, clindamycin, and erythromycin for Staphylococcus aureus. J. Infect. Dis., 153, 593-600.
2. BAKKER-WOUDENBERD, I. A. J. M., LOKERSE, A. F., TEN KATE, M. T., MELISSEN, P. M. B., VAN VIANEN, W., VAN ETTEN, E. W. M. (1993): Liposomes as carriers of antimicrobial agents or immunomodulatory agents in the treatments of infections. Eur J Clin Microbiol., 12, Suppl 1, 61-67.
3. BAŞ, A. L, ELMAS, M., ŞIMŞEK, A., TRAŞ, B., YAZAR, E., HADIMLI, H. H. (2000): Efficacies of free and liposome-encapsulated enrofloxacin (Baytril®) against Staphylococcus aureus infection in Turkish shepherd dog neutrophils in vitro. Revue Med. Vet., 151, 415-420.
4. BAŞ, A.L., ŞIMŞEK, A., ÇORLU, M., YAZAR, E., ELMAS, M., DEǦIM, Z. G. (2002): Determination of intracellular concentrations of free and two type liposome-encapsulated enrofloxacin in Anatolian shepherd dog monocytes. J. Vet. Med. B., 49, 289-293.
5. BAUDITZ, R. (1998): Results of clinical studies with Baytril in dogs and cats. Vet. Med. Rev., 2, 137-40.
6. BERMUDEZ, L. E. (1994): Use of liposome preparation to treat mycobacterial infections. Immunobiology, 191, 578-583.
7. BOOGAERTS, M. A., MALBRAIN, S., SCHEERS, W., VERWILGHEN, R. L. (1986): Effects of quinolones on granulocyte function in vitro. Infection, 14, 258-262.
8. CABANES, A., REIG, F., GARCIA-ANTON, J. M., ARBOIX, M. (1995): Sustained release of liposome-encapsulated enrofloxacin after intramuscular administration in rabbits. Am. J. Vet. Res., 56, 1498-1501.
9. CABANES, A., REIG, F., GARCIA-ANTON, J. M., ARBOIX, M. (1998): Evaluation of free and liposome encapsulated gentamicin for intramuscular sustained release in rabbits. Res. Vet. Sci., 64, 213-217.
10. CARLIER, M. B., SCORNEAUX, B., ZENEBERGH, A., DESNOTTES, J. F., TULKENS, P. M. (1990): Cellular uptake, localization and activity of fluoroquinolones in uninfected and infected macrophages. J. Antimicrob. Chemother., 26, Suppl. B, 27-39.
11. th Ed., Butterworth-Heinemann Ltd., Great Britain.
12. DESNOTTES, J. F., DIALLO, N. (1994): Effect of sparfloxacin on Staphylococcus aureus adhesiveness and phagocytosis. J. Antimicrob. Chemother., 33, 737-746.
13. DÜZGÜNEŞ, N., ASHTEKAR, D. R., FLASHER, D. A., GHORI, N., DEBS, R. J., FRIEND, D. S., GANGADHARAM, P. R. (1991): Treatment of M. avium-intracellulare complex infection in beige mice with free and liposome-encapsulated streptomycin: role of liposome type and duration of treatment. J. Infect. Dis., 164, 143-151.
14. EASMON, C. S. F., CRANE, J. P. (1985): Uptake of ciprofloxacin by macrophages. J. Clin. Pathol., 38, 442-444.
15. ELLBOGEN, M. H., OLSEN, K. M., GENTRY-NIELSEN, M. J., PREHEIM, L. C. (2003): Efficacy of liposome-encapsulated ciprofloxacin compared with ciprofloxacin and ceftriaxone in a rat model of pneumococcal pneumonia. J. Antimicrob. Chemother., 51, 83-91.
16. EMMEN, F., STORM, G. (1987): Liposomes in treatment of infectious diseases. Pharm. Weekbl Sci., 9, 162-171.
17. FIELDING, R. M. (1991): Liposomal drug delivery: Advantages and limitations from a clinical pharmacokinetic and therapeutic perspective. Clin. Pharmacokinet. 21, 3, 155-164.
18. GANGADHARAM, P. R. J., ASHTEKAR, D. A., GHORI, N., GOLDSTEIN, J. A., DEBS, R. J., DÜZGÜNEŞ, N. (1991): Chemotherapeutic potential of free and liposome-encapsulated streptomycin against experimental M. avium complex infections in beige mice. J. Antimicrob. Chemother., 28, 425-435.
19. HAND, W. L., KING-THOMPSON, N. L. (1989): The entry of antibiotics into human monocytes. J. Antimicrob. Chemother., 23, 681-689.
20. th Ed., Williams & Wilkins, Baltimore.
21. HWANG, K. J. (1987): Liposome pharmacokinetics, p: 109-156. In: Liposomes: from biophysics to therapeutics, M. J. Ostro, Marcel Dekker, Inc., New York.
22. th Ed., p: 676-730, Philadelphia, USA.
23. KIRBY, C. J., GREGORIADIS, G. A. (1994): Simple procedure for preparing liposomes capable of high encapsulation efficiency under mild conditions: In: Liposome Technology, Gregoriadis, G. Vol. 1, p. 19-27, CRC Press Inc., Boca Raton, Fla.
24. MADGWICK, L., MAYER, S. and KEEN, P. (1989). Penetration of antibiotics into bovine neutrophils and their activity against intracellular Staphylococcus aureus. J. Antimicrob. Chemother., 24, 709-718.
25. MAJUMDAR, S., FLASHER, D., FRIEND, D. S., NASSOS, P., YAJKO, D., HADLEY, W. K. DÜZGÜNEŞ, N. (1992): Efficacies of liposome-encapsulated streptomycin and ciprofloxacin against M. avium-M. intracellulare complex infections in human peripheral blood monocytes/macrophages. Antimicrob. Agents Chemother., 36, 2808- 2815.
26. McGEE, Z. A., GORBY, G. L., UPDIKE, S. (1989): The use of neutrophils, macrophages and organ cultures to assess the penetration of human cells by antimicrobials. Prog. Drug Res., 33, 83-92.
27. McKELLAR, Q. (1996): Clinical relevance of the pharmacologic properties of fluoroqinolones. Compend. Contin. Educ. Pract. Vet. Suppl., 18, 14-20.
28. NAGAHATA, H., KOCIBA, G., RETIER, J. A., CUOTO, G. (1991): Analysis of selected variables in the under-agarose assay for chemotactic re-sponse of canine neutrophils. A. J. Vet. Res., 52; 6, 966-969.
29. NIELSEN, S. L., OBEL, N., STORGAARD, M., ANDERSON, P. L. (1997): The effect of quinolones on the intracellular killing of Staphylococcus aureus in neutrophil granulocytes, J. Antimicrob. Chemother., 39, 617-622.
30. OMRI, A., BEAULAC, C., BOUHAJIB, M., MONTPLAISIR, S., SHARKAWI, M., LAGACE, J. (1994): Pulmonary retention of free and liposome-encapsulated tobramycin after intratracheal administration in uninfected rats and rats infected with P. aeruginosa. Antimicrob. Agents Chemother., 38, 1090-1095.
31. SCHALM, O. W. (1977): The canine monocyte, Canine practice, 4, 23-26.
32. SCHEER, M. (1987): Studies on antimicrobial activity of Baytril. Vet. Med. Rev., 2, 90-99.
33. SCHOVERS, E. J., VAN LEENGOED, A. M. G., VERHEIJDEN, J. H. M., NIEWOLD, T. A. (1999): Effects of enrofloxacin on porcine phagocytosis function, J. Antimicrob. Chemother., 43, 9, 2138-2143.
34. SCHREIER, H., LEVY, M., MIHALKO, P. (1987): Sustained release of liposome-encapsulated gentamicin and fate of phospholipid following intramuscular injection in mice. J. Control. Rel., 5, 187-192.
35. SHAW, S. E., ANDERSON, N. V. (1984): Isolation and functional analysis of normal canine blood monocytes and resident alveolar macrophages, Am. J. Vet. Res., 45, 87-90.
36. SZOKA, F. C. (1990): The future of liposomal drug delivery. Biotech. Appl. Biochem., 12, 496-500.
37. TYCZKOWSKA, K., HEDEEN, K. M., AUCOIN, D. P., ARONSON, A. (1989): High performance liquid chromatographic for the simultaneous determination of enrofloxacin and its primary metabolite ciprofloxacin in canine serum and prostatic tissue. J. Chromatog., 493, 337-346.
38. VANCUTSEM, P. M., BABISH, J. G., SCHWARK, W. S. (1990): The fluoroquinolone antimicrobials: structure, antimicrobial activity, pharmacokinetics, clinical use in domestic animals and toxicity. Cornell. Vet., 80, 173-86.
39. VAN den BROEK P. J. (1989): Antimicrobial drugs, microorganisms, and phagocytes. Rev. Infect. Dis. 11, 213-245.
40. VAN DER AUWERA, P., MATSUMOTO, T., HUSSON, M. (1998): Intraphagocytic penetration of antibiotics. J. Antimicrob. Chemother. 22, 185-192.
41. VAN DER AUWERA P., PRINZ, G., PETRIKKOS, G. (1991): Activity of intracellular antibiotics. Infection, 19, 216-223.
42. VAN RENSBURG, C. E., JOONE, G., ANDERSON, R. (1989): An in vitro investigation of the intraphagocytic bioactivity of difloxacin, ciprofloxacin, pefloxacin and fleroxacin. Chemotherapy, 35, 273-277.
43. WALKER, R. D., STEIN, G. E., HAUPTMAN, J. G, McDONALD, K. H. (1992): Pharmacokinetic evaluation of enrofloxacin administered orally to healthy dogs. Am. J. Vet. Res., 53, 2315-2319.
44. WONG J. P., YANG, H., BLASETTI, K. L., SCHNELL, G., CONLEY, J., SCHOFIELD, L. N. (2003): Liposome delivery of ciprofloxacin against intracellular Francisella tularensis infection. J Control Release., 30, 92, 3, 265-73.
45. ZOU, Y. Y., LING, Y. H., REDDY, S., PRIEBE, W., PEREZ-SOLER, R. (1995): Effect of vesicle size and lipid composition on the in vivo tumor selectivity and toxicity of the non-cross-resistant anthracycline Anamycin incorporated in liposomes. Int. J. Cancer, 61, 666-671.