Variability in Delivered Dose from Pressurized Metered-Dose Inhaler Formulations Due to a Delay between Shake and Fire

Journal of Aerosol Medicine and Pulmonary Drug Delivery

Volumn 30, Issue 1, 2017, Pages 71-79

  Hatley, Ross H M ^a   Parker, Jacob ^a   Pritchard, John N ^a   Von Hollen, Dirk ^a  

^a PHILIPS RESEARCH LABORATORIES   (Germany)

Author keywords

creaming; delivered drug; formulation; pressurized metered dose inhaler (pMDI); sedimentation; shake fire delay

Indexed keywords

BECLOMETASONE DIPROPIONATE; BUDESONIDE PLUS FORMOTEROL; EXCIPIENT; FLUTICASONE PROPIONATE; SALBUTAMOL; SALBUTAMOL SULFATE; ANTIASTHMATIC AGENT; BRONCHODILATING AGENT;

ARTICLE; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METERED DOSE INHALER; PHYSICAL CHEMISTRY; PHYSICAL PARAMETERS; PRESCRIPTION; COMPARATIVE STUDY; EQUIPMENT DESIGN; HUMAN; INHALATIONAL DRUG ADMINISTRATION; TIME FACTOR; TISSUE DISTRIBUTION;

ADMINISTRATION, INHALATION; ANTI-ASTHMATIC AGENTS; BRONCHODILATOR AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DELIVERY SYSTEMS; EQUIPMENT DESIGN; HUMANS; METERED DOSE INHALERS; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 85010301100     PISSN: 19412711     EISSN: 19412703     Source Type: Journal    
DOI: 10.1089/jamp.2015.1284     Document Type: Article

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