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COI: 1:CAS:528:DC%2BD2MXjsFCltrc%3D, PID: 15843671, This article explains the pathophysiology of atherosclerosis and its link with inflammation. Several different inflammatory markers, with different biological activities, contribute to the risk of coronary artery disease
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•• Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med. 2005;352(16):1685–95. doi:10.1056/NEJMra043430. This article explains the pathophysiology of atherosclerosis and its link with inflammation. Several different inflammatory markers, with different biological activities, contribute to the risk of coronary artery disease.
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N Engl J Med
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Hansson, G.K.1
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COI: 1:CAS:528:DC%2BC2MXhslelurk%3D, PID: 25682027
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Rein P, Saely CH, Silbernagel G, Vonbank A, Mathies R, Drexel H, et al. Systemic inflammation is higher in peripheral artery disease than in stable coronary artery disease. Atherosclerosis. 2015;239(2):299–303. doi:10.1016/j.atherosclerosis.2015.01.021.
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Association of platelet to lymphocyte ratio with inflammation and severity of coronary atherosclerosis in patients with stable coronary artery disease
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COI: 1:CAS:528:DC%2BC28XhsVWrtrrK, PID: 25922197
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Akboga MK, Canpolat U, Yayla C, Ozcan F, Ozeke O, Topaloglu S, et al. Association of platelet to lymphocyte ratio with inflammation and severity of coronary atherosclerosis in patients with stable coronary artery disease. Angiology. 2016;67(1):89–95. doi:10.1177/0003319715583186.
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Kinoshita T, Asai T, Takashima N, Hosoba S, Suzuki T, Kambara A, et al. Preoperative C-reactive protein and atrial fibrillation after off-pump coronary bypass surgery. Eur J Cardiothorac Surg. 2011;40(6):1298–303. doi:10.1016/j.ejcts.2011.03.027.
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Yo CH, Lee SH, Chang SS, Lee MC, Lee CC. Value of high-sensitivity C-reactive protein assays in predicting atrial fibrillation recurrence: a systematic review and meta-analysis. BMJ Open. 2014;4(2), e004418. doi:10.1136/bmjopen-2013-004418.
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8
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84878337221
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Biomarkers in atrial fibrillation: a clinical review
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COI: 1:CAS:528:DC%2BC3sXos1ynu7s%3D, PID: 23386711, This is a review about the cardiac biomarkers and their use in risk stratification of patients with atrial fibrillation
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• Hijazi Z, Oldgren J, Siegbahn A, Granger CB, Wallentin L. Biomarkers in atrial fibrillation: a clinical review. Eur Heart J. 2013;34(20):1475–80. doi:10.1093/eurheartj/eht024. This is a review about the cardiac biomarkers and their use in risk stratification of patients with atrial fibrillation.
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Eur Heart J
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Hijazi, Z.1
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J Am Coll Cardiol
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• Aulin J, Siegbahn A, Hijazi Z, Ezekowitz MD, Andersson U, Connolly SJ, et al. Interleukin-6 and C-reactive protein and risk for death and cardiovascular events in patients with atrial fibrillation. Am Heart J. 2015;170(6):1151–60. doi:10.1016/j.ahj.2015.09.018. In patients from the RE-LY study, interleukin-6 was associated with increased risk of stroke, major bleeding, vascular death, and the composite of thromboembolic events independent of clinical risk factors.
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• Hijazi Z, Aulin J, Andersson U, Alexander JH, Gersh B, Granger CB, et al. Biomarkers of inflammation and risk of cardiovascular events in anticoagulated patients with atrial fibrillation. Heart. 2016;102(7):508–17. doi:10.1136/heartjnl-2015-308887. Among the 18,201 patients in the ARISTOTLE study on anticoagulation, interleukin-6 and C-reactive protein were associated with increased risk of death.
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12
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84922480777
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Growth differentiation factor 15, a marker of oxidative stress and inflammation, for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial
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COI: 1:CAS:528:DC%2BC2cXhvFGkur3F, PID: 25294786
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Wallentin L, Hijazi Z, Andersson U, Alexander JH, De Caterina R, Hanna M, et al. Growth differentiation factor 15, a marker of oxidative stress and inflammation, for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial. Circulation. 2014;130(21):1847–58. doi:10.1161/CIRCULATIONAHA.
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• January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland Jr JC, et al. American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014;64(21):e1–76. doi:10.1016/j.jacc.2014.03.022. This is one of the guidelines on atrial fibrillation, with epidemiological data, classification, pathophysiology and management of patients with this arrhythmia.
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14
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84950104119
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Heart disease and stroke statistics—2016 Update: a report from the American Heart Association
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PID: 26673558, This article is published annually by the American Heart Association with updated epidemiological data of cardiovascular diseases
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• Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, et al. Heart disease and stroke statistics—2016 Update: a report from the American Heart Association. Circulation. 2016;133(4):e38-360. doi:10.1161/CIR.0000000000000350. This article is published annually by the American Heart Association with updated epidemiological data of cardiovascular diseases.
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Circulation
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•• Libby P, Ridker PM, Hansson GK. Progress and challenges in translating the biology of atherosclerosis. Nature. 2011;473(7347):317–25. doi:10.1038/nature10146. It is an important article on the developmental stages of atherosclerosis, the role of inflammation and the biomarkers, with animal experiments and human studies.
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Libby P. Inflammation in atherosclerosis. Arterioscler Thromb Vasc Biol. 2012;32(9):2045–51. doi:10.1161/ATVBAHA.108.179705.
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Wong BW, Meredith A, Lin D, McManus BM. The biological role of inflammation in atherosclerosis. Can J Cardiol. 2012;28(6):631–41. doi:10.1016/j.cjca.2012.06.023.
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Can J Cardiol
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84931268779
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The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis
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COI: 1:CAS:528:DC%2BC2MXhtVSqsrjL, PID: 26086357
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Hovland A, Jonasson L, Garred P, Yndestad A, Aukrust P, Lappegård KT, et al. The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis. Atherosclerosis. 2015;241(2):480–94. doi:10.1016/j.atherosclerosis.2015.05.038.
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Atherosclerosis
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19
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Libby P, Lichtman AH, Hansson GK. Immune effector mechanisms implicated in atherosclerosis: from mice to humans. Immunity. 2013;38(6):1092–104. doi:10.1016/j.immuni.2013.06.009.
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Libby, P.1
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84959062601
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Libby P, Bornfeldt KE, Tall AR. Atherosclerosis: successes, surprises, and future challenges. Circ Res. 2016;118(4):531–4. doi:10.1161/CIRCRESAHA.116.308334.
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•• Hu YF, Chen YJ, Lin YJ, Chen SA. Inflammation and the pathogenesis of atrial fibrillation. Nat Rev Cardiol. 2015;12(4):230–43. doi:10.1038/nrcardio.2015.2. This article discusses the inflammatory pathways (risk factors, cytokines, immune factors), which are involved in the pathophysiology of atrial fibrillation.
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85027933168
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Immune regulators of inflammation in obesity-associated type 2 diabetes and coronary artery disease
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COI: 1:CAS:528:DC%2BC2cXhsVOntLjK, PID: 25106001
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Strissel KJ, Denis GV, Nikolajczyk BS. Immune regulators of inflammation in obesity-associated type 2 diabetes and coronary artery disease. Curr Opin Endocrinol Diabetes Obes. 2014;21(5):330–8. doi:10.1097/MED.0000000000000085.
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84959327018
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• Seccia TM, Caroccia B, Muiesan ML, Rossi GP. Atrial fibrillation and arterial hypertension: a common duet with dangerous consequences where the renin angiotensin-aldosterone system plays an important role. Int J Cardiol. 2016;206:71–6. doi:10.1016/j.ijcard.2016.01.007. This article discusses the frequency of atrial fibrillation in patients with hypertension, the role of the renin-angiotensin-aldosterone system in the induction of fibrosis and cardiac remodeling and the role of aldosterone in the development of arrhythmia.
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Dual opposing roles of adaptive immunity in hypertension
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Idris-Khodja N, Mian MO, Paradis P, Schiffrin EL. Dual opposing roles of adaptive immunity in hypertension. Eur Heart J. 2014;35(19):1238–44. doi:10.1093/eurheartj/ehu119.
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Eur Heart J
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Hajhosseiny R, Matthews GK, Lip GY. Metabolic syndrome, atrial fibrillation, and stroke: tackling an emerging epidemic. Heart Rhythm. 2015;12(11):2332–43. doi:10.1016/j.hrthm.2015.06.038.
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Prevalence and implications of subclinical coronary artery disease in patients with atrial fibrillation
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COI: 1:CAS:528:DC%2BC38Xis1Cntb4%3D, PID: 22044645
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Stellos K, Rahmann A, Kilias A, Ruf M, Sopova K, Stamatelopoulos K, et al. Expression of platelet-bound stromal cell-derived factor-1 in patients with non-valvular atrial fibrillation and ischemic heart disease. J Thromb Haemost. 2012;10(1):49–55. doi:10.1111/j.1538-7836.2011.04547.
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Atrial fibrillation and risk of ST-segment-elevation versus non-ST-segment-elevation myocardial infarction: The Atherosclerosis Risk in Communities (ARIC) study
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PID: 25918127, This is a study that evaluated the association between atrial fibrillation and incident myocardial infarction in 14,462 participants without baseline coronary artery disease
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• Soliman EZ, Lopez F, O’Neal WT, Chen LY, Bengtson L, Zhang ZM, et al. Atrial fibrillation and risk of ST-segment-elevation versus non-ST-segment-elevation myocardial infarction: The Atherosclerosis Risk in Communities (ARIC) study. Circulation. 2015;131(21):1843–50. doi:10.1161/CIRCULATIONAHA.114.014145. This is a study that evaluated the association between atrial fibrillation and incident myocardial infarction in 14,462 participants without baseline coronary artery disease.
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Circulation
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O’Neal WT, Efird JT, Qureshi WT, Yeboah J, Alonso A, Heckbert SR, Nazarian S, Soliman EZ. Coronary Artery calcium progression and atrial fibrillation: The multi-ethnic study of atherosclerosis. Circ Cardiovasc Imaging. 2015; 8(12). doi: 10.1161/CIRCIMAGING.115.003786.
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•• Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, et al. 2016 ESC guidelines for the management of atrial fibrillation developed in collaboration with EACTS: the task force for the management of atrial fibrillation of the European Society of Cardiology (ESC) developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC endorsed by the European Stroke Organisation (ESO). Eur Heart J. 2016. doi:10.1093/eurheartj/ehw210. It is the last published guideline on atrial fibrillation, with epidemiological data, classification, pathophysiology, and management of patients with this arrhythmia.
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