RPN13/ADRM1 inhibitor reverses immunosuppression by myeloid-derived suppressor cells

Oncotarget

Volumn 7, Issue 42, 2016, Pages 68489-68502

  Soong, Ruey Shyang ^a,b,c   Anchoori, Ravi K ^a   Yang, Benjamin ^a   Yang, Andrew ^a   Tseng, Ssu Hsueh ^a   He, Liangmei ^a   Tsai, Ya Chea ^a   Roden, Richard B S ^a   Hung, Chien Fu ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Immunosuppression; MDSCs; Proteasome; RPN13; Stat3

Indexed keywords

ARGINASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 12; PIPERIDONE DERIVATIVE; PROTEASOME INHIBITOR; RA 190; STAT3 PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; ADRM1 PROTEIN, MOUSE; BENZYLIDENE DERIVATIVE; CELL ADHESION MOLECULE; RA190;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CONTROL; CANCER SURVIVAL; CD8+ T LYMPHOCYTE; CELL FUNCTION; CONTROLLED STUDY; DRUG EFFECT; FEMALE; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; MOUSE; MYELOID-DERIVED SUPPRESSOR CELL; NONHUMAN; OVARY TUMOR; PROTEIN EXPRESSION; TUMOR MICROENVIRONMENT; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; CELL PROLIFERATION; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; KAPLAN MEIER METHOD; METABOLISM; RNA INTERFERENCE; TUMOR CELL LINE;

ANIMALS; BENZYLIDENE COMPOUNDS; CD8-POSITIVE T-LYMPHOCYTES; CELL ADHESION MOLECULES; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; FEMALE; HEK293 CELLS; HUMANS; IMMUNE TOLERANCE; KAPLAN-MEIER ESTIMATE; MICE, INBRED C57BL; MYELOID-DERIVED SUPPRESSOR CELLS; OVARIAN NEOPLASMS; RNA INTERFERENCE; STAT3 TRANSCRIPTION FACTOR; TUMOR MICROENVIRONMENT;

EID: 85009720824     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/ONCOTARGET.12095     Document Type: Article

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