Occurrence of halogenated flame retardants in commercial seafood species available in European markets

Food and Chemical Toxicology

Volumn 104, Issue , 2017, Pages 35-47

  Aznar Alemany, Òscar ^a   Trabalón, Laura ^b   Jacobs, Silke ^c   Barbosa, Vera Liane ^d   Tejedor, Margarita Fernández ^e   Granby, Kit ^f   Kwadijk, Christiaan ^g   Cunha, Sara C ^h   Ferrari, Federico ⁱ   Vandermeersch, Griet ^j   Sioen, Isabelle ^c   Verbeke, Wim ^c   Vilavert, Lolita ^b   Domingo, José L ^b   Eljarrat, Ethel ^a   Barceló, Damià ^a,k  

^a INSTITUTE OF ENVIRONMENTAL ASSESSMENT AND WATER RESEARCH   (Spain)

^b UNIVERSITAT ROVIRA I VIRGILI   (Spain)

^c GHENT UNIVERSITY   (Belgium)

^d Unit of Upgrading of Fishery and Aquaculture Products (U VPPA)   (Portugal)

^e Institute of Agrifood Research and Technology (IRTA)   (Spain)

^f TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^g WAGENINGEN UNIVERSITY   (Netherlands)

^h UNIVERSITY OF PORTO   (Portugal)

ⁱ Gariga di Podenzano (PC)   (Italy)

^j INSTITUTE FOR AGRICULTURAL AND FISHERIES RESEARCH ILVO   (Belgium)

^k CATALAN INSTITUTE FOR WATER RESEARCH ICRA   (Spain)

more..

Author keywords

2,4,6 TBP; Effect of cooking; Margin of exposure; PBDEs; Risk assessment

Indexed keywords

2,2',4,4',5,5' HEXABROMODIPHENYL ETHER; FLAME RETARDANT; BROMINATED HYDROCARBON; WATER POLLUTANT;

ARTICLE; COMPARATIVE STUDY; CONTAMINATED MUSSEL; CONTAMINATED ORGANISM; COOKING; DEEP SEA SPECIES; ENVIRONMENTAL PARAMETERS; EUROPEAN; EXPOSURE; FOOD CONTAMINATION; FOOD INTAKE; FOOD QUALITY; HALOGENATION; HEALTH HAZARD; MARKET; MEDITERRANEAN SEA; NONHUMAN; QUALITY CONTROL; RISK ASSESSMENT; SEA BREAM; SEA FOOD; ANALYSIS; ANIMAL; ECONOMICS; EUROPE; FISH; WATER POLLUTANT;

ANIMALS; EUROPE; FISHES; FLAME RETARDANTS; FOOD CONTAMINATION; HYDROCARBONS, BROMINATED; SEAFOOD; WATER POLLUTANTS, CHEMICAL;

EID: 85009476537     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2016.12.034     Document Type: Article

References (81)

1. Alaee, M., Arias, P., Sjödin, A., Bergman, Å., An overview of commercially used brominated flame retardants, their applications, their use patterns in different countries/regions and possible modes of release. Environ. Int. 29 (2003), 683–689, 10.1016/S0160-4120(03)00121-1.
2. Alonso, M.B., Azevedo, A., Torres, J.P.M., Dorneles, P.R., Eljarrat, E., Barcelo, D., Lailson-Brito, J., Maim, O., Anthropogenic (PBDE) and naturally-produced (MeO-PBDE) brominated compounds in cetaceans - a review. Sci. Total Environ. 481 (2014), 619–634, 10.1016/j.scitotenv2014.02.022.
3. Bakke, T., Boitsov, S., Brevik, E., Gabrielsen, G.W., Green, N., Helgason, L.B., Klungsøyr, J., Leknes, H., Miljeteig, C., Måge, A., Rolfsnes, B.E., Savinova, T., Schlabach, M., Skaare, B.B., Valdersnes, S., Mapping selected organic contaminants in the Barents Sea 2007. online, 2008, Norwegian Institute for Water Research (NIVA) accessed: August 2015.
4. Barghi, M., Shin, E.S., Son, M.H., Choi, S.D., Pyo, H., Chang, Y.S., Hexabromocyclododecane (HBCD) in the Korean food basket and estimation of dietary exposure. Environ. Pollut. 213 (2016), 268–277, 10.1016/j.envpol.2016.02.026.
5. Barón, E., Eljarrat, E., Barceló, D., Analytical method for the determination of halogenated norbornene flame retardants in environmental and biota matrices by gas chromatography coupled to tandem mass spectrometry. J. Chromatogr. A 1248 (2012), 154–160, 10.1016/j.chroma.2012.05.079.
6. Barón, E., Eljarrat, E., Barceló, D., Gas chromatography/tandem mass spectrometry method for the simultaneous analysis of 19 brominated compounds in environmental and biological samples. Anal. Bioanal. Chem., 2014, 10.1007/s00216-014-8196-7.
7. Ben Ameur, W., Ben Hassine, S., Eljarrat, E., El Megdiche, Y., Trabelsi, S., Hammami, B., Barcelo, D., Driss, M.R., Polybrominated diphenyl ethers and their methoxylated analogs in mullet (Mugil cephalus) and sea bass (Dicentrarchus labrax) from Bizerte Lagoon, Tunisia. Mar. Environ. Res. 72 (2011), 258–264, 10.1016/j.marenvres.2011.09.009.
8. Bergman, A., Brominated flame retardants in a global environmental perspective. Proceedings of the Workshop on Brominated Aromatic Flame Retardants, Skokloster, 24–26 October 1989, 1990, National Chemicals Inspectorate (KEMI), Solna.
9. Branchi, I., Capone, F., Alleva, E., Costa, L.G., Polybrominated diphenyl ethers: neurobehavioral effects following developmental exposure. NeuroToxicology 24 (2003), 449–462, 10.1016/S0161-813X(03)00020-2.
10. Christensen, J.H., Platz, J., Screening of polybrominated diphenyl ethers in blue mussels, marine and freshwater sediments in Denmark. J. Environ. Monit. 3 (2001), 543–547, 10.1039/b105501c.
11. Convention, S. (2008). < http://chm.pops.int/> [accessed: June 2015].
12. Costa, L.G., Giordano, G., Is decabromodiphenyl ether (BDE-209) a developmental neurotoxicant?. NeuroToxicology 32 (2011), 9–24, 10.1016/j.neuro.2010.12.010.
13. Covaci, A., Harrad, S., Abdallah, M.A.E., Ali, N., Law, R.J., Herzke, D., de Wit, C.A., Novel brominated flame retardants: a review of their analysis, environmental fate and behaviour. Environ. Int 37 (2011), 532–556, 10.1016/j.envint.2010.11.007.
14. Cruz, R., Cunha, S.C., Casal, S., Brominated flame retardants and seafood safety: a review. Environ. Int 77 (2015), 116–131 http://dx.doi.org/10.1016/j.envint.2015.01.001.
15. de la Cal, A., Eljarrat, E., Barceló, D., Determination of 39 polybrominated diphenyl ether congeners in sediment samples using fast selective pressurized liquid extraction and purification. J. Chromatogr. A 1021 (2003), 165–173, 10.1016/j.chroma.2003.09.023.
16. de Wit, C.A., An overview of brominated flame retardants in the environment. Chemosphere 46 (2002), 583–624 http://dx.doi.org/10.1016/S0045-6535(01)00225-9.
17. de Wit, C.A., Alaee, M., Muir, D.C.G., Levels and trends of brominated flame retardants in the Arctic. Chemosphere 64 (2006), 209–233, 10.1016/j.chemosphere.2005.12.029.
18. Domingo, J.L., Influence of cooking processes on the concentrations of toxic metals and various organic environmental pollutants in food: a review of the published literature. Crit. Rev. Food Sci. Nutr. 51 (2010), 29–37, 10.1080/10408390903044511.
19. Domingo, J.L., Bocio, A., Falco, G., Llobet, J.M., Exposure to PBDEs and PCDEs associated with the consumption of edible marine species. Environ. Sci. Technol. 40 (2006), 4394–4399, 10.1021/es060484k.
20. EFSA, EFSA Panel on Contaminants in the Food Chain (CONTAM). Scientific Opinion on Hexabromocyclododecanes (HBCDDs) in Food. 2011 online http://www.efsa.europa.eu/en/efsajournal/doc/2296.pdf accessed: August 2015.
21. EFSA, Panel on Contaminants in the Food Chain (CONTAM). Scientific Opinion on Polybrominated Diphenyl Ethers (PBDEs) in Food. 2011 online http://www.efsa.europa.eu/sites/default/files/scientific_output/files/main_documents/2156.pdf accessed: March 2016.
22. EFSA, Panel on Contaminants in the Food Chain (CONTAM). Scientific Opinion on Tetrabromobisphenol a (TBBPA) and its Derivatives in Food. online, 2011 accessed: March 2016.
23. EFSA, Panel on Contaminants in the Food Chain (CONTAM). Scientific Opinion on Brominated Flame Retardants (BFRs) in Food: Brominated Phenols and Their Derivatives. 2012 online http://www.efsa.europa.eu/en/efsajournal/pub/2908.htm# accessed: August 2015.
24. Eljarrat, E., De La Cal, A., Raldua, D., Duran, C., Barcelo, D., Occurrence and bioavailability of polybrominated diphenyl ethers and hexabromocyclododecane in sediment and fish from the Cinca River, a tributary of the Ebro River (Spain). Environ. Sci. Technol. 38 (2004), 2603–2608, 10.1021/es0301424.
25. Eljarrat, E., Guerra, P., Martinez, E., Farre, M., Alvarez, J.G., Lopez-Teijon, M., Barcelo, D., Hexabromocyclododecane in human breast milk: levels and enantiomeric patterns. Environ. Sci. Technol. 43 (2009), 1940–1946, 10.1021/es802919e.
26. Eljarrat, E., Labandeira, A., Marsh, G., Raldúa, D., Barceló, D., Decabrominated diphenyl ether in river fish and sediment samples collected downstream an industrial park. Chemosphere 69 (2007), 1278–1286, 10.1016/j.chemosphere.2007.05.052.
27. Eljarrat, E., Lacorte, S., Barceló, D., Optimization of congener-specific analysis of 40 polybrominated diphenyl ethers by gas chromatography/mass spectrometry. J. Mass Spectrom. 37 (2002), 76–84, 10.1002/jms.262.
28. Gorga, M., Martínez, E., Ginebreda, A., Eljarrat, E., Barceló, D., Determination of PBDEs, HBB, PBEB, DBDPE, HBCD, TBBPA and related compounds in sewage sludge from Catalonia (Spain). Sci. Total Environ. 444 (2013), 51–59, 10.1016/j.scitotenv.2012.11.066.
29. Granby, K., Cederberg, T. L. 2007. LC-MS/MS analysis of hexabromocyclododecane (HBCD) isomers and tetrabromobisphenol A (TBBPA) and levels in Danish fish for food consumption. The 4th International Workshop on Brominated Flame Retardants, Amsterdam.
30. Guerra, P., Alaee, M., Jiménez, B., Pacepavicius, G., Marvin, C., MacInnis, G., Eljarrat, E., Barceló, D., Champoux, L., Fernie, K., Emerging and historical brominated flame retardants in peregrine falcon (Falco peregrinus) eggs from Canada and Spain. Environ. Int. 40 (2012), 179–186, 10.1016/j.envint.2011.07.014.
31. Guerra, P., Eljarrat, E., Barcelo, D., Simultaneous determination of hexabromocyclododecane, tetrabromobisphenol A, and related compounds in sewage sludge and sediment samples from Ebro River basin (Spain). Anal. Bioanal. Chem. 397 (2010), 2817–2824, 10.1007/s00216-010-3670-3.
32. Guerra, P., Eljarrat, E., Barceló, D., Analysis and occurrence of emerging brominated flame retardants in the Llobregat River basin. J. Hydrology 383 (2010), 39–43, 10.1016/j.jhydrol.2009.06.052.
33. Guerra, P., Fernie, K., Jiménez, B., Pacepavicius, G., Shen, L., Reiner, E., Eljarrat, E., Barceló, D., Alaee, M., Dechlorane Plus and related compounds in peregrine falcon (Falco peregrinus) eggs from Canada and Spain. Environ. Sci. Technol. 45 (2011), 1284–1290, 10.1021/es103333j.
34. Harner, T., Shoeib, M., Diamond, M., Ikonomou, M., Stern, G., Passive sampler derived air concentrations of PBDEs along an urban–rural transect: spatial and temporal trends. Chemosphere 64 (2006), 262–267, 10.1016/j.chemosphere.2005.12.018.
35. Hong, Q.I., Liyan, L., Hongliang, J., Li, Y.I.F., Ren, N.Q.I., Hong, Y., Xinyuan, S., Lili, F., Yongsheng, D., Dechlorane plus in surficial water and sediment in a northeastern Chinese river. Environ. Sci. Technol. 44 (2010), 2305–2308, 10.1021/es9027106.
36. Houde, M., Berryman, D., de Lafontaine, Y., Verreault, J., Novel brominated flame retardants and dechloranes in three fish species from the St. Lawrence River, Canada. Sci. Total Environ. 479 (2014), 48–56, 10.1016/j.scitotenv.2014.01.105.
37. Houlbrque, F., Hervé-Fernández, P., Teyssié, J.L., Oberhaënsli, F., Boisson, F., Jeffree, R., Cooking makes cadmium contained in Chilean mussels less bioaccessible to humans. Food Chem. 126 (2011), 917–921, 10.1016/j.foodchem.2010.11.078.
38. Jacobs, S., Sioen, I., Jacxsens, L., Domingo, J.L., Sloth, J.J., Marques, A., Verbeke, W., Risk assessment of methylmercury in five European countries considering the national seafood consumption patterns. Food Chem. Toxicol., 2017 http://dx.doi.org/10.1016/j.fct.2016.10.026.
39. Jacobs, S., Sioen, I., Pieniak, Z., De Henauw, S., Maulvault, A.L., Reuver, M., Fait, G., Cano-Sancho, G., Verbeke, W., Consumers' health risk–benefit perception of seafood and attitude toward the marine environment: insights from five European countries. Environ. Res. 143 (2015), 11–19 Part B http://dx.doi.org/10.1016/j.envres.2015.02.029.
40. Johansson, I., Heas-Moisan, K., Guiot, N., Munschy, C., Tronczynski, J., Polybrominated diphenyl ethers (PBDEs) in mussels from selected French coastal sites: 1981-2003. Chemosphere 64 (2006), 296–305, 10.1016/j.chemosphere.2005.12.014.
41. Labandeira, A., Eljarrat, E., Barceló, D., Congener distribution of polybrominated diphenyl ethers in feral carp (Cyprinus carpio) from the Llobregat River, Spain. Environ. Pollut. 146 (2007), 188–195, 10.1016/j.envpol.2006.04.037.
42. Lacorte, S., Ikonomou, M.G., Fischer, M., A comprehensive gas chromatography coupled to high resolution mass spectrometry based method for the determination of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in environmental samples. J. Chromatogr. A 1217 (2010), 337–347, 10.1016/j.chroma.2009.11.024.
43. Lankova, D., Kockovska, M., Lacina, O., Kalachova, K., Pulkrabova, J., Hajslova, J., Rapid and simple method for determination of hexabromocyclododecanes and other LC-MS-MS-amenable brominated flame retardants in fish rapid detection in food and feed. Anal. Bioanal. Chem. 405 (2013), 7829–7839, 10.1007/s00216-013-7076-x.
44. Löfstrand, K., Liu, X.T., Lindqvist, D., Jensen, S., Asplund, L., Seasonal variations of hydroxylated and methoxylated brominated diphenyl ethers in blue mussels from the Baltic Sea. Chemosphere 84 (2011), 527–532, 10.1016/j.chemosphere.2011.01.001.
45. Losada, S., Roach, A., Roosens, L., Santos, F.J., Galceran, M.T., Vetter, W., Neels, H., Covaci, A., Biomagnification of anthropogenic and naturally-produced organobrominated compounds in a marine food web from Sydney Harbour, Australia. Environ. Int. 35 (2009), 1142–1149, 10.1016/j.envint.2009.07.008.
46. Marques, A., Lourenço, H.M., Nunes, M.L., Roseiro, C., Santos, C., Barranco, A., Rainieri, S., Langerholc, T., Cencic, A., New tools to assess toxicity, bioaccessibility and uptake of chemical contaminants in meat and seafood. Food Res. Int. 44 (2011), 510–522, 10.1016/j.foodres.2010.12.003.
47. Medeiros Vinci, R., Jacxsens, L., Van Loco, J., Matsiko, E., Lachat, C., de Schaetzen, T., Canfyn, M., Van Overmeire, I., Kolsteren, P., De Meulenaer, B., Assessment of human exposure to benzene through foods from the Belgian market. Chemosphere 88 (2012), 1001–1007 http://dx.doi.org/10.1016/j.chemosphere.2012.03.044.
48. Mikula, P., Svobodova, Z., Brominated flame retardants in the environment: their sources and effects (a review). Acta Vet. BRNO 75 (2006), 587–599, 10.2754/avb200675040587.
49. MSFD, Directive 2008/56/EC of the European Parliament and of the Council of 17 June 2008 Establishing a Framework for Community Action in the Field of Marine Environmental Policy (Marine Strategy Framework Directive). 2008 online http://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32008L0056 accessed: April 2016.
50. Norén, K., Meironyté, D., Certain organochlorine and organobromine contaminants in Swedish human milk in perspective of past 20–30 years. Chemosphere 40 (2000), 1111–1123, 10.1016/S0045-6535(99)00360-4.
51. Paepke, O., Petersen, M., Ebsen, P., Neugebauer, F., Opel, M., Brominated Flame Retardants in European Food Samples Collected in 2007 to 2009. 2010.
52. Pardo, O., Beser, M.I., Yusà, V., Beltrán, J., Probabilistic risk assessment of the exposure to polybrominated diphenyl ethers via fish and seafood consumption in the Region of Valencia (Spain). Chemosphere vol. 104 (2014), 7–14 http://dx.doi.org/10.1016/j.chemosphere.2013.12.084.
53. Parera, J., Abalos, M., Santos, F.J., Galceran, M.T., Abad, E., Polychlorinated dibenzo-p-dioxins, dibenzofurans, biphenyls, paraffins and polybrominated diphenyl ethers in marine fish species from Ebro River Delta (Spain). Chemosphere 93 (2013), 499–505, 10.1016/j.chemosphere.2013.06.022.
54. Pena-Abaurrea, M., Weijs, L., Ramos, L., Borghesi, N., Corsolini, S., Neels, H., Blust, R., Covaci, A., Anthropogenic and naturally-produced organobrominated compounds in bluefin tuna from the Mediterranean Sea. Chemosphere 76 (2009), 1477–1482, 10.1016/j.chemosphere.2009.07.004.
55. Perelló, G., Martí-Cid, R., Castell, V., Llobet, J.M., Domingo, J.L., Concentrations of polybrominated diphenyl ethers, hexachlorobenzene and polycyclic aromatic hydrocarbons in various foodstuffs before and after cooking. Food Chem. Toxicol. 47 (2009), 709–715 http://dx.doi.org/10.1016/j.fct.2008.12.030.
56. Poma, G., Binelli, A., Volta, P., Roscioli, C., Guzzella, L., Evaluation of spatial distribution and accumulation of novel brominated flame retardants, HBCD and PBDEs in an Italian subalpine lake using zebra mussel (Dreissena polymorpha). Environ. Sci. Pollut. Res. 21 (2014), 9655–9664, 10.1007/s11356-014-2826-7.
57. PSWP, Directive 2013/39/EU of the European Parliament and of the Council of 12 August 2013 Amending Directives 2000/60/EC and 2008/105/EC as Regards Priority Substances in the Field of Water Policy. 2013 online http://eur-lex.europa.eu/legal-content/en/ALL/?uri=CELEX%3A32013L0039 accessed: April 2016.
58. REACH, Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 Concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), Establishing a European Chemicals Agency, Amending Directive 1999/45/EC and Repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as Well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC. 2006 online http://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32006R1907 accessed: August 2015.
59. Sánchez-Avila, J., Fernandez-Sanjuan, M., Vicente, J., Lacorte, S., Development of a multi-residue method for the determination of organic micropollutants in water, sediment and mussels using gas chromatography–tandem mass spectrometry. J. Chromatogr. A 1218 (2011), 6799–6811, 10.1016/j.chroma.2011.07.056.
60. Schecter, A., Haffner, D., Colacino, J., Patel, K., Päpke, O., Opel, M., Birnbaum, L., Polybrominated diphenyl ethers (PBDEs) and hexabromocyclodecane (HBCD) in composite U.S. food samples. Environ. Health Perspect. 118 (2010), 357–362, 10.1289/ehp.0901345.
61. Shanmuganathan, D., Megharaj, M., Chen, Z., Naidu, R., Polybrominated diphenyl ethers (PBDEs) in marine foodstuffs in Australia: residue levels and contamination status of PBDEs. Mar. Pollut. Bull. 63 (2011), 154–159 http://dx.doi.org/10.1016/j.marpolbul.2011.06.002.
62. Siddique, S., Xian, Q., Abdelouahab, N., Takser, L., Phillips, S.P., Feng, Y.-L., Wang, B., Zhu, J., Levels of dechlorane plus and polybrominated diphenylethers in human milk in two Canadian cities. Environ. Int. 39 (2012), 50–55, 10.1016/j.envint.2011.09.010.
63. Sverko, E., Tomy, G.T., Marvin, C.H., Zaruk, D., Reiner, E., Helm, P.A., Hill, B., McCarry, B.E., Dechlorane plus levels in sediment of the lower Great lakes. Environ. Sci. Technol. 42 (2007), 361–366, 10.1021/es0710104.
64. Swartenbroux, F., Albajedo, B., Angelidis, M., Aulne, M., Bartkevics, V., Besada, V., Bignert, A., Bitterhof, A., Hallikainen, A., Hoogenboom, R., Jorhem, L., Jud, M., Law, R., Licht Cederberg, D., McGovern, E., Miniero, R., Schneider, R., Velikova, V., Verstraete, F., Vinas, L.S.V., Piha, H., MARINE STRATEGY FRAMEWORK DIRECTIVE Task Group 9 Contaminants in Fish and Other Seafood. 2010 online http://mcc.jrc.ec.europa.eu/documents/201406241428.pdf accessed: April 2016.
65. Szlinder-Richert, J., Barska, I., Usydus, Z., Grabic, R., Polybrominated diphenyl ethers (PBDEs) in selected fish species from the southern Baltic Sea. Chemosphere 78 (2010), 695–700 http://dx.doi.org/10.1016/j.chemosphere.2009.12.004.
66. Teuten, E.L., Xu, L., Reddy, C.M., Two abundant bioaccumulated halogenated compounds are natural products. Science 307 (2005), 917–920, 10.1126/science.1106882.
67. Torre, A.D.L., Pacepavicius, G., Shen, L., Reiner, E., Jimenez, B., Alaee, M., Martinez, M.A., Dechlorane plus and related compounds in Spanish air. Organohalogen Compd. 72 (2010), 929–932.
68. Torre, A.D.L., Shen, L., Reiner, E., Jimenez, B., Alaee, M., Martinez, M.A., New halogenated norbornene flame retardants in sewage sludge. Organohalogen Compd. 72 (2010), 1060–1063.
69. United States Environmental Protection Agency, An Alternative Assessment for the Flame Retardant Decabromodiphenyl Ether (DecaBDE). (Doi), 2014.
70. Van Ael, E., Covaci, A., Blust, R., Bervoets, L., Persistent organic pollutants in the Scheldt estuary: environmental distribution and bioaccumulation. Environ. Int. 48 (2012), 17–27, 10.1016/j.envint.2012.06.017.
71. van Leeuwen, S.P.J., de Boer, J., Brominated flame retardants in fish and shellfish – levels and contribution of fish consumption to dietary exposure of Dutch citizens to HBCD. Mol. Nutr. Food Res. 52 (2008), 194–203, 10.1002/mnfr.200700207.
72. Vandermeersch, G., Lourenço, H.M., Alvarez-Muñoz, D., Cunha, S., Diogène, J., Cano-Sancho, G., Sloth, J.J., Kwadijk, C., Barcelo, D., Allegaert, W., Bekaert, K., Fernandes, J.O., Marques, A., Robbens, J., Environmental contaminants of emerging concern in seafood – European database on contaminant levels. Environ. Res. 143, Part B, 2015, 29–45 http://dx.doi.org/10.1016/j.envres.2015.06.011.
73. Vetter, W., Marine halogenated natural products of environmental relevance. Reviews of Environmental Contamination and Toxicology, vol. 188, 2006, Springer, New York, 1–57, 10.1007/978-0-387-32964-2_1.
74. Vetter, W., Stoll, E., Garson, M.J., Fahey, S.J., Gaus, C., Muller, J.F., Sponge halogenated natural products found at parts-per-million levels in marine mammals. Environ. Toxicol. Chem. 21 (2002), 2014–2019, 10.1002/etc.5620211002.
75. Villaverde-de-Saa, E., Valls-Cantenys, C., Quintana, J.B., Rodil, R., Cela, R., Matrix solid-phase dispersion combined with gas chromatography-mass spectrometry for the determination of fifteen halogenated flame retardants in mollusks. J. Chromatogr. A 1300 (2013), 85–94, 10.1016/j.chroma.2013.05.064.
76. Wan, Y., Wiseman, S., Chang, H., Zhang, X., Jones, P.D., Hecker, M., Kannan, K., Tanabe, S., Hu, J., Lam, M.H.W., Giesy, J.P., Origin of hydroxylated brominated diphenyl ethers: natural compounds or man-made flame retardants?. Environ. Sci. Technol. 43 (2009), 7536–7542, 10.1021/es901357u.
77. WFD, Directive 2000/60/EC of the European Parliament and of the Council of 23 October 2000 Establishing a Framework for Community Action in the Field of Water Policy. 2000 online http://faolex.fao.org/docs/pdf/eur23005.pdf accessed: April 2016.
78. Whitfield, F.B., Helidoniotis, F., Shaw, K.J., Svoronos, D., Distribution of bromophenols in species of marine algae from eastern Australia. J. Agric. Food Chem. 47 (1999), 2367–2373, 10.1021/jf981080h.
79. Wiseman, S.B., Wan, Y., Chang, H., Zhang, X.W., Hecker, M., Jones, P.D., Giesy, J.P., Polybrominated diphenyl ethers and their hydroxylated/methoxylated analogs: environmental sources, metabolic relationships, and relative toxicities. Mar. Pollut. Bull. 63 (2011), 179–188, 10.1016/j.marpolbul.2011.02.008.
80. Wu, T., Wang, S., Huang, H., Zhang, S., Diastereomer-specific uptake, translocation, and toxicity of hexabromocyclododecane diastereoisomers to maize. J. Agric. Food Chem. 60 (2012), 8528–8534, 10.1021/jf302682p.
81. Zhu, B., Lai, N.L.S., Wai, T.-C., Chan, L.L., Lam, J.C.W., Lam, P.K.S., Changes of accumulation profiles from PBDEs to brominated and chlorinated alternatives in marine mammals from the South China Sea. Environ. Int. 66 (2014), 65–70, 10.1016/j.envint.2014.01.023.