Glucose Control in the ICU: A Continuing Story

Journal of Diabetes Science and Technology

Volumn 10, Issue 6, 2016, Pages 1372-1381

  Preiser, Jean Charles ^a   Chase, J Geoffrey ^b   Hovorka, Roman ^c   Joseph, Jeffrey I ^d   Krinsley, James S ^e   De Block, Christophe ^f   Desaive, Thomas ^g   Foubert, Luc ^h   Kalfon, Pierre ⁱ   Pielmeier, Ulrike ^j   Van Herpe, Tom ^k   Wernerman, Jan ^l  

^a ERASME HOSPITAL   (Belgium)

^b UNIVERSITY OF CANTERBURY   (New Zealand)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

^e Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^f ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^g UNIVERSITY OF LIÈGE   (Belgium)

^h OLV HOSPITAL   (Belgium)

ⁱ Louis Pasteur Hospital   (France)

^j AALBORG UNIVERSITY   (Denmark)

^k UNIVERSITY OF LEUVEN   (Belgium)

^l KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

more..

Author keywords

continuous glucose control; diabetes; intensive care; time in band

Indexed keywords

BLOOD GLUCOSE MONITORING; CLINICAL OUTCOME; CLINICAL TRIAL (TOPIC); DIABETES MELLITUS; DIAGNOSTIC VALUE; GLYCEMIC CONTROL; HEALTH CARE COST; HUMAN; HYPERGLYCEMIA; INTENSIVE CARE UNIT; MEASUREMENT ACCURACY; MEDICAL RESEARCH; MORTALITY; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; WORKLOAD; ANALYSIS; DEVICES; GLUCOSE BLOOD LEVEL; PHYSIOLOGIC MONITORING; PROCEDURES;

GLUCOSE BLOOD LEVEL;

BLOOD GLUCOSE; INTENSIVE CARE UNITS; MONITORING, PHYSIOLOGIC;

EID: 85009448130     PISSN: None     EISSN: 19322968     Source Type: Journal    
DOI: 10.1177/1932296816648713     Document Type: Review

References (69)

1. van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in the critically ill patients. N Engl J Med. 2001; 345: 1359-1367.
2. Finfer S, Chittock DR, Su SY, et al. Intensive versus conventional glucose control in critically ill patients. N Engl J Med. 2009; 360: 1283-1297.
3. De La, Rosa GDC, Donado JH, Restrepo AH, et al. Strict glycaemic control in patients hospitalised in a mixed medical and surgical intensive care unit: a randomised clinical trial. Crit Care. 2008; 12: R120.
4. Brunkhorst FM, Engel C, Bloos F, et al. Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med. 2008; 358: 125-139.
5. Preiser JC, Devos P, Ruiz-Santana S, et al. A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study. Intensive Care Med. 2009; 35: 1738-1748.
6. Arabi YM, Dabbagh OC, Tamim HM, et al. Intensive versus conventional insulin therapy: a randomized controlled trial in medical and surgical critically ill patients. Crit Care Med. 2008; 36: 3190-3197.
7. Annane D, Cariou A, Maxime V, et al. Corticosteroid treatment and intensive insulin therapy for septic shock in adults: a randomized controlled trial. JAMA. 2010; 303: 341-348.
8. Kalfon P, Giraudeau B, Ichai C, et al. Tight computerized versus conventional glucose control in the ICU: a randomized controlled trial. Intensive Care Med. 2014; 40: 171-181.
9. Marik PE,. Classic critical care papers. In: Marik PE, ed. Handbook of Evidence-Based Critical Care. New York, NY: Springer; 2010: 7-12.
10. Moghissi ES, Korytkowski MT, DiNardo M, et al. American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control. Diabetes Care. 2009; 32: 1119-1131.
11. American Diabetes Association. Standards of medical care in diabetes-2014. Diabetes Care. 2014; 37 (suppl 1): S14-S80.
12. Ichai C, Preiser JC., International recommendations for glucose control in adult non diabetic critically ill patients. Crit Care. 2010; 14: R166.
13. Kavanagh BP, McCowen KC., Clinical practice. Glycemic control in the ICU. N Engl J Med. 2010; 363: 2540-2546.
14. Dellinger RP, Levy MM, Rhodes A, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013; 41: 580-637.
15. Qaseem A, Humphrey LL, Chou R, Snow V, Shekelle P., Use of intensive insulin therapy for the management of glycemic control in hospitalized patients: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2011; 154: 260-267.
16. Jacobi J, Bircher N, Krinsley J, et al. Guidelines for the use of an insulin infusion for the management of hyperglycemia in critically ill patients. Crit Care Med. 2012; 40: 3251-3276.
17. Egi M, Bellomo R, Stachowski E, French CJ, Hart G., Variability of blood glucose concentration and short-term mortality in critically ill patients. Anesthesiology. 2006; 105: 244-252.
18. Krinsley JS, Egi M, Kiss A, et al. Diabetic status and the relation of the three domains of glycemic control to mortality in critically ill patients: an international multicenter cohort study. Crit Care. 2013; 17: R37.
19. Lanspa MJ, Dickerson J, Morris AH, Orme JF, Holmen J, Hirshberg EL., Coefficient of glucose variation is independently associated with mortality in critically ill patients receiving intravenous insulin. Crit Care. 2014; 18: R86.
20. Boom DT, Sechterberger MK, Rijkenberg S, et al. Insulin treatment guided by subcutaneous continuous glucose monitoring compared to frequent point-of-care measurement in critically ill patients: a randomized controlled trial. Crit Care. 2014; 18: 453.
21. Wernerman J, Desaive T, Finfer S, et al. Continuous glucose control in the ICU: report of a 2013 round table meeting. Crit Care. 2014; 18: 226.
22. Eslami S, de Keizer NF, de Jonge E, Schultz MJ, Abu-Hanna A., A systematic review on quality indicators for tight glycaemic control in critically ill patients: need for an unambiguous indicator reference subset. Crit Care. 2008; 12: R139.
23. De Block CE, Gios J, Verheyen N, et al. Randomized evaluation of glycemic control in the medical intensive care unit using real-time continuous glucose monitoring (REGIMEN Trial). Diabetes Technol Ther. 2015; 17: 889-898.
24. Holzinger U, Warszawska J, Kitzberger R, et al. Real-time continuous glucose monitoring in critically ill patients: a prospective randomized trial. Diabetes Care. 2010; 33: 467-472.
25. Wilinska ME, Hovorka R., Glucose control in the intensive care unit by use of continuous glucose monitoring: what level of measurement error is acceptable? Clin Chem. 2014; 60: 1500-1509.
26. Van Herpe T, De Moor B, van den Berghe G, Mesotten D,. Modeling of effect of glucose sensor errors on insulin dosage and glucose bolus computed by LOGIC-Insulin. Clin Chem. 2014; 60: 1510-1518.
27. Strasma PJ, Finfer S, Flower O, et al. Use of an intravascular fluorescent continuous glucose sensor in ICU patients. J Diabetes Sci Technol. 2015; 9: 762-770.
28. Van Herpe T, De Brabanter J, Beullens M, De Moor B, van den Berghe G,. Glycemic penalty index for adequately assessing and comparing different blood glucose control algorithms. Crit Care. 2008; 12: R24.
29. Vogelzang M, van der Horst IC, Nijsten MW., Hyperglycaemic index as a tool to assess glucose control: a retrospective study. Crit Care. 2004; 8: R122-R127.
30. Finfer S, Wernerman J, Preiser JC, et al. Consensus recommendations on measurement of blood glucose and reporting glycemic control in critically ill adults. Crit Care. 2013; 17: 229.
31. Penning S, Pretty C, Preiser JC, Shaw GM, Desaive T, Chase JG., Glucose control positively influences patient outcome: a retrospective study. J Crit Care. 2015; 30: 455-459.
32. Mackenzie IM, Whitehouse T, Nightingale PG., The metrics of glycaemic control in critical care. Intensive Care Med. 2011; 37: 435-443.
33. Krinsley JS, Preiser JC., Time in blood glucose range 70 to 140 mg/dl >80% is strongly associated with increased survival in non-diabetic critically ill adults. Crit Care. 2015; 19: 179.
34. Abdelmalak BB, Knittel J, Abdelmalak JB, et al. Preoperative blood glucose concentrations and postoperative outcomes after elective non-cardiac surgery: an observational study. Br J Anaesth. 2014; 112: 79-88.
35. Hsu CW, Sun SF, Lin SL, Huang HH, Wong KF., Moderate glucose control results in less negative nitrogen balances in medical intensive care unit patients: a randomized, controlled study. Crit Care. 2012; 16: R56.
36. Waeschle RM, Brauer A, Hilgers R, et al. Hypoglycaemia and predisposing factors among clinical subgroups treated with intensive insulin therapy. Acta Anaesthesiol Scand. 2014; 58: 223-234.
37. Egi M, Bellomo R, Stachowski E, et al. Blood glucose concentration and outcome of critical illness: the impact of diabetes. Crit Care Med. 2008; 36: 2249-2255.
38. Krinsley JS., Glycemic control, diabetic status, and mortality in a heterogeneous population of critically ill patients before and during the era of intensive glycemic management: six and one-half years experience at a university-affiliated community hospital. Semin Thorac Cardiovasc Surg. 2006; 18: 317-325.
39. Falciglia M, Freyberg RW, Almenoff PL, D'Alessio DA, Render ML., Hyperglycemia-related mortality in critically ill patients varies with admission diagnosis. Crit Care Med. 2009; 37: 3001-3009.
40. Lanspa MJ, Hirshberg EL, Phillips GD, Holmen J, Stoddard G, Orme J., Moderate glucose control is associated with increased mortality compared with tight glucose control in critically ill patients without diabetes. Chest. 2013; 143: 1226-1234.
41. Sechterberger MK, Bosman RJ, Oudemans-van Straaten HM, et al. The effect of diabetes mellitus on the association between measures of glycaemic control and ICU mortality: a retrospective cohort study. Crit Care. 2013; 17: R52.
42. Egi M, Bellomo R, Stachowski E, et al. The interaction of chronic and acute glycemia with mortality in critically ill patients with diabetes. Crit Care Med. 2011; 39: 105-111.
43. Plummer MP, Bellomo R, Cousins CE, et al. Dysglycaemia in the critically ill and the interaction of chronic and acute glycaemia with mortality. Intensive Care Med. 2014; 40: 973-980.
44. van den Berghe G, Wilmer A, Milants I, et al. Intensive insulin therapy in mixed medical/surgical intensive care units: benefit versus harm. Diabetes. 2006; 55: 3151-3159.
45. Van Ackerbroeck S, Schepens T, Janssens K, et al. Incidence and predisposing factors for the development of disturbed glucose metabolism and DIabetes mellitus AFter Intensive Care admission: the DIAFIC study. Crit Care. 2015; 19: 355.
46. van den Berghe G, Wouters PJ, Kesteloot K, Hilleman DE., Analysis of healthcare resource utilization with intensive insulin therapy in critically ill patients. Crit Care Med. 2006; 34: 612-616.
47. Krinsley JS, Jones RL., Cost analysis of intensive glycemic control in critically ill adult patients. Chest. 2006; 129: 644-650.
48. Sadhu AR, Ang AC, Ingram-Drake LA, Martinez DS, Hsueh WA, Ettner SL., Economic benefits of intensive insulin therapy in critically Ill patients: the targeted insulin therapy to improve hospital outcomes (TRIUMPH) project. Diabetes Care. 2008; 31: 1556-1561.
49. van Hooijdonk RT, Steuten LM, Kip MM, et al. Health economic evaluation of a strict glucose control guideline implemented using point-of-care testing in three intensive care units in the Netherlands. Appl Health Econ Health Policy. 2015; 13: 399-407.
50. Krinsley JS., Is glycemic control of the critically ill cost-effective? Hosp Pract. 2014; 42: 53-58.
51. Aragon D., Evaluation of nursing work effort and perceptions about blood glucose testing in tight glycemic control. Am J Crit Care. 2006; 15: 370-377.
52. Rood E, Bosman RJ, van der Spoel JI, Taylor P, Zandstra DF., Use of a computerized guideline for glucose regulation in the intensive care unit improved both guideline adherence and glucose regulation. J Am Med Inform Assoc. 2005; 12: 172-180.
53. Evans A, Le Compte A, Tan CS, et al. Stochastic targeted (STAR) glycemic control: design, safety, and performance. J Diabetes Sci Technol. 2012; 6: 102-115.
54. Van Herpe T, Mesotten D, Wouters PJ, et al. LOGIC-insulin algorithm-guided versus nurse-directed blood glucose control during critical illness: the LOGIC-1 single-center, randomized, controlled clinical trial. Diabetes Care. 2013; 36: 188-194.
55. Pachler C, Plank J, Weinhandl H, et al. Tight glycaemic control by an automated algorithm with time-variant sampling in medical ICU patients. Intensive Care Med. 2008; 34: 1224-1230.
56. Vogelzang M, Zijlstra F, Nijsten MW., Design and implementation of GRIP: a computerized glucose control system at a surgical intensive care unit. BMC Med Inform Decis Mak. 2005; 5: 38.
57. Pielmeier U, Andreassen S, Juliussen B, Chase JG, Nielsen BS, Haure P., The Glucosafe system for tight glycemic control in critical care: a pilot evaluation study. J Crit Care. 2010; 25: 97-104.
58. Boyd JC, Bruns DE., Performance requirements for glucose assays in intensive care units. Clin Chem. 2014; 60: 1463-1465.
59. Arnal JM, Garnero A, Novonti D, et al. Feasibility study on full closed-loop control ventilation (IntelliVent-ASV) in ICU patients with acute respiratory failure: a prospective observational comparative study. Crit Care. 2013; 17: R196.
60. Weller P, Roudsari A, Carson E,. Clinical decision support systems. In: Feng DD, ed. Biomedical Information Technology. Amsterdam, Netherlands: Elsevier; 2008: 375-391.
61. Christiansen JS, Svendsen PA, Deckert T., Insulin treatment and state of control before, during, and after connection to a glucose controlled insulin infusion system (Biostator). Horm Metab Res Suppl. 1979; 8: 131-134.
62. Thabit H, Tauschmann M, Allen JM, et al. Home Use of an artificial beta cell in type 1 diabetes. N Engl J Med. 2015; 373: 2129-2140.
63. Kropff J, Del FS, Place J, et al. 2 month evening and night closed-loop glucose control in patients with type 1 diabetes under free-living conditions: a randomised crossover trial. Lancet Diabetes Endocrinol. 2015; 3: 939-947.
64. Nimri R, Muller I, Atlas E, et al. MD-Logic overnight control for 6 weeks of home use in patients with type 1 diabetes: randomized crossover trial. Diabetes Care. 2014; 37: 3025-3032.
65. Yatabe T, Yamazaki R, Kitagawa H, et al. The evaluation of the ability of closed-loop glycemic control device to maintain the blood glucose concentration in intensive care unit patients. Crit Care Med. 2011; 39: 575-578.
66. Leelarathna L, English SW, Thabit H, et al. Feasibility of fully automated closed-loop glucose control using continuous subcutaneous glucose measurements in critical illness: a randomized controlled trial. Crit Care. 2013; 17: R159.
67. Okabayashi T, Shima Y, Sumiyoshi T, et al. Intensive versus intermediate glucose control in surgical intensive care unit patients. Diabetes Care. 2014; 37: 1516-1524.
68. Bequette BW., Analysis of algorithms for intensive care unit blood glucose control. J Diabetes Sci Technol. 2007; 1: 813-824.
69. Cinotti R, Ichai C, Orban JC, et al. Effects of tight computerized glucose control on neurological outcome in severely brain injured patients: a multicenter sub-group analysis of the randomized-controlled open-label CGAO-REA study. Crit Care. 2014; 18: 498.