Aspirin prevents TNF-α-induced endothelial cell dysfunction by regulating the NF-κB-dependent miR-155/eNOS pathway: Role of a miR-155/eNOS axis in preeclampsia

Free Radical Biology and Medicine

Volumn 104, Issue , 2017, Pages 185-198

  Kim, Joohwan ^a   Lee, Kyu Sun ^a   Kim, Ji Hee ^a   Lee, Dong Keon ^a   Park, Minsik ^a   Choi, Seunghwan ^a   Park, Wonjin ^a   Kim, Suji ^a   Choi, Yoon Kyoung ^a   Hwang, Jong Yun ^a   Choe, Jongseon ^a   Won, Moo Ho ^a   Jeoung, Dooil ^b   Lee, Hansoo ^b   Ryoo, Sungwoo ^b   Ha, Kwon Soo ^a   Kwon, Young Guen ^c   Kim, Young Myeong ^a  

^a Kangwon National University College of Medicine   (South Korea)

^b Kangwon National University   (South Korea)

^c Yonsei University   (South Korea)

Author keywords

Aspirin; Endothelial dysfunction; ENOS; MiRNA 155; NF B; ROS

Indexed keywords

ACETYLSALICYLIC ACID; CYCLIC GMP; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE PEROXIDASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; MICRORNA 155; PROSTAGLANDIN E2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 3; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SOS PROTEIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; XANTHINE OXIDASE; MICRORNA; MIRN155 MICRORNA, HUMAN; NOS3 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; BIOGENESIS; BIRTH WEIGHT; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOWN REGULATION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; FEMALE; GENE EXPRESSION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INTRACELLULAR SIGNALING; MATERNAL PLASMA; NONHUMAN; NORMAL HUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOGENESIS; PHENOTYPE; PREECLAMPSIA; PREGNANT WOMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; PROTEIN SYNTHESIS REGULATION; SYSTOLIC BLOOD PRESSURE; TROPHOBLAST; VASODILATATION; WILD TYPE; ADULT; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; METABOLISM; PATHOLOGY; PREGNANCY; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL;

ADULT; ASPIRIN; ENDOTHELIAL CELLS; FEMALE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MICRORNAS; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE III; PRE-ECLAMPSIA; PREGNANCY; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85009438170     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2017.01.010     Document Type: Article

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