-
1
-
-
0041966056
-
Reversal of human senescence: Roles of p16 and p53 pathways
-
Beausejour CM, Krotolica A, Galimi F, Narita M, Lowe SW, Yawen P, Campisi J (2003) Reversal of human senescence: roles of p16 and p53 pathways. EMBO J 22:4212-4222
-
(2003)
EMBO J
, vol.22
, pp. 4212-4222
-
-
Beausejour, C.M.1
Krotolica, A.2
Galimi, F.3
Narita, M.4
Lowe, S.W.5
Yawen, P.6
Campisi, J.7
-
2
-
-
35348843011
-
David von Hansemann: Contributions to oncology: Context, comments, and translations
-
Birkhauser Verlag, Basel
-
Bignold LP, Coghland BLD, Jersmann HPA (2007) David von Hansemann: contributions to oncology: context, comments, and translations. Birkhauser Verlag, Basel
-
(2007)
-
-
Bignold, L.P.1
Coghland, B.L.D.2
Jersmann, H.P.A.3
-
3
-
-
35948949789
-
APC and colon cancer: Two hits for one
-
Ceol CJ, Pellman D, Zon LI (2007) APC and colon cancer: two hits for one. Nat Med 13:1286-1287
-
(2007)
Nat Med
, vol.13
, pp. 1286-1287
-
-
Ceol, C.J.1
Pellman, D.2
Zon, L.I.3
-
4
-
-
36849004185
-
Deep senescent human fibroblasts show diminished DNA damage foci but retain checkpoint capacity to oxidative stress
-
Chen JH, Ozanne SE (2006) Deep senescent human fibroblasts show diminished DNA damage foci but retain checkpoint capacity to oxidative stress. FEBS Lett 580:6669-6673
-
(2006)
FEBS Lett
, vol.580
, pp. 6669-6673
-
-
Chen, J.H.1
Ozanne, S.E.2
-
5
-
-
72949096792
-
Senescence in tumors: Evidence from mice and humans
-
CoUado M, Serrano M (2010) Senescence in tumors: evidence from mice and humans. Nat Rev Cancer 10:51-57
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 51-57
-
-
CoUado, M.1
Serrano, M.2
-
6
-
-
23244447893
-
Tumor biology: Senescence in premalignant tumors
-
Collado M, Gil J, Efeyan A, Guerra C, Schuhmacher AJ, Baradas M, Benguria A, Zaballos A, Flores JM, Barbacid M, Beach D, Serrano M (2005) Tumor biology: senescence in premalignant tumors. Nature 436:642
-
(2005)
Nature
, vol.436
, pp. 642
-
-
Collado, M.1
Gil, J.2
Efeyan, A.3
Guerra, C.4
Schuhmacher, A.J.5
Baradas, M.6
Benguria, A.7
Zaballos, A.8
Flores, J.M.9
Barbacid, M.10
Beach, D.11
Serrano, M.12
-
7
-
-
34447543913
-
CeUular senescence in cancer and aging
-
Collado M, Blasco MA, Serrano M (2007) CeUular senescence in cancer and aging. Cell 130:223-233
-
(2007)
Cell
, vol.130
, pp. 223-233
-
-
Collado, M.1
Blasco, M.A.2
Serrano, M.3
-
8
-
-
84889400309
-
Polyploidy in cell differentiation
-
D'Amato F (1989) Polyploidy in cell differentiation. Caryologia 42:183-211
-
(1989)
Caryologia
, vol.42
, pp. 183-211
-
-
D'Amato, F.1
-
9
-
-
77950932096
-
Persistent telomere damage induces bypass of mitosis and tetraploidy
-
Davoli T, Denchi EL, de Lange T (2010) Persistent telomere damage induces bypass of mitosis and tetraploidy. Cell 141:81-93
-
(2010)
Cell
, vol.141
, pp. 81-93
-
-
Davoli, T.1
Denchi, E.L.2
de Lange, T.3
-
10
-
-
79959209781
-
Polyploid tumor cells elicit paradiploid progeny through depolyploidizing divisions and regulated autophagy degradation
-
Erenpreisa J, Salmina K, Huna A, Kosmacek EA, Cragg MS, lanzini F, Anisimov AP (2011) Polyploid tumor cells elicit paradiploid progeny through depolyploidizing divisions and regulated autophagy degradation. Cell Biol Int 35:687-695
-
(2011)
Cell Biol Int
, vol.35
, pp. 687-695
-
-
Erenpreisa, J.1
Salmina, K.2
Huna, A.3
Kosmacek, E.A.4
Cragg, M.S.5
lanzini, F.6
Anisimov, A.P.7
-
11
-
-
0014525828
-
Chromosome aberrations in cultured cells deprived of single essential amino acid
-
Freed JJ, Schatz SA (1969) Chromosome aberrations in cultured cells deprived of single essential amino acid. Exp Cell Res 55:393-409
-
(1969)
Exp Cell Res
, vol.55
, pp. 393-409
-
-
Freed, J.J.1
Schatz, S.A.2
-
12
-
-
77955516632
-
Cellular senescence predict treatment outcome in metastasized colorectal cancer
-
Haugstetter AM, Loddenkemper C, Lenze D, Grone J, Standfus C, Petersen I, Schmitt CA (2010) Cellular senescence predict treatment outcome in metastasized colorectal cancer. Br J Cancer 103:505-509
-
(2010)
Br J Cancer
, vol.103
, pp. 505-509
-
-
Haugstetter, A.M.1
Loddenkemper, C.2
Lenze, D.3
Grone, J.4
Standfus, C.5
Petersen, I.6
Schmitt, C.A.7
-
13
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hay flick L, Moorhead PS (1961) The serial cultivation of human diploid cell strains. Exp Cell Res 25:585-621
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hay flick, L.1
Moorhead, P.S.2
-
14
-
-
3242765346
-
Endomitotic reduplication mechanisms in ascites tumors of the mouse
-
Levan A, Hauschka TS (1953) Endomitotic reduplication mechanisms in ascites tumors of the mouse. J Natl Cancer Inst 14:1-43
-
(1953)
J Natl Cancer Inst
, vol.14
, pp. 1-43
-
-
Levan, A.1
Hauschka, T.S.2
-
15
-
-
0018358261
-
Senescent human diploid cells in culture: Survival, DNA synthesis and morphology
-
Matsumura T, Zerrudo Z, Hayflick L (1979) Senescent human diploid cells in culture: survival, DNA synthesis and morphology. J Gerontol 34:328-334
-
(1979)
J Gerontol
, vol.34
, pp. 328-334
-
-
Matsumura, T.1
Zerrudo, Z.2
Hayflick, L.3
-
16
-
-
77950267128
-
Polyploidy: The link between senescence and cancer
-
Mosieniak G, Sikora E (2010) Polyploidy: the link between senescence and cancer. Curr Pharm Des 16:734-740
-
(2010)
Curr Pharm Des
, vol.16
, pp. 734-740
-
-
Mosieniak, G.1
Sikora, E.2
-
17
-
-
49749107218
-
Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy
-
Puig P-E, Guilly M-N, Bouchot A, Droin N, Cathelin D, Bouyer F, Favier L, Ghiringhelli F, Kroemer G, Solary E, Martin F, Chauffert B (2008) Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy. Cell Biol Int 32:1031-1043
-
(2008)
Cell Biol Int
, vol.32
, pp. 1031-1043
-
-
Puig, P.-E.1
Guilly, M.-N.2
Bouchot, A.3
Droin, N.4
Cathelin, D.5
Bouyer, F.6
Favier, L.7
Ghiringhelli, F.8
Kroemer, G.9
Solary, E.10
Martin, F.11
Chauffert, B.12
-
18
-
-
16844373387
-
Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers
-
Roberson RS, Kussick SJ, Vallieres E, Chen S-YJ, Wu DY (2005) Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers. Cancer Res 65:2795-2803
-
(2005)
Cancer Res
, vol.65
, pp. 2795-2803
-
-
Roberson, R.S.1
Kussick, S.J.2
Vallieres, E.3
Chen, S.-Y.J.4
Wu, D.Y.5
-
19
-
-
0034602815
-
Chromosomal instability and cytoskeletal defects in oral cancer
-
Saunders WS, Shuster M, Huang X, Gharaibe B, Enyenihi AH, Petersen I, Gollin SM (2000) Chromosomal instability and cytoskeletal defects in oral cancer. Proc Natl Acad Sci 97:303-308
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 303-308
-
-
Saunders, W.S.1
Shuster, M.2
Huang, X.3
Gharaibe, B.4
Enyenihi, A.H.5
Petersen, I.6
Gollin, S.M.7
-
20
-
-
2342570379
-
Hallmarks of senescence in carcinogenesis and cancer therapy
-
Shay JW, Roninson IB (2004) Hallmarks of senescence in carcinogenesis and cancer therapy. Oncogene 23:2919-2933
-
(2004)
Oncogene
, vol.23
, pp. 2919-2933
-
-
Shay, J.W.1
Roninson, I.B.2
-
21
-
-
34548314311
-
Mitotic bypass via an occult cell cycle phase following DNA topoisomerase II inhibition in p53 functional human tumor cells
-
Smith PJ, Marquez N, Wiltshire M, Chappell S, Njoh K, Campbell L, Khan I A, Silvestre O, Errington RJ (2007) Mitotic bypass via an occult cell cycle phase following DNA topoisomerase II inhibition in p53 functional human tumor cells. Cell Cycle 6:2071-2081
-
(2007)
Cell Cycle
, vol.6
, pp. 2071-2081
-
-
Smith, P.J.1
Marquez, N.2
Wiltshire, M.3
Chappell, S.4
Njoh, K.5
Campbell, L.6
Khan, I.A.7
Silvestre, O.8
Errington, R.J.9
-
22
-
-
0037086268
-
DNA damage is able to induce senescence in tumor cells in vitro and in vivo
-
te Poele RH, Okorokov AL, Jardine L, Cummings J, Joel SP (2002) DNA damage is able to induce senescence in tumor cells in vitro and in vivo. Cancer Res 62:1876-1883
-
(2002)
Cancer Res
, vol.62
, pp. 1876-1883
-
-
te Poele, R.H.1
Okorokov, A.L.2
Jardine, L.3
Cummings, J.4
Joel, S.P.5
-
24
-
-
0006373991
-
Spatial relationships in the replication of chromosomal DNA
-
Walen KH (1965) Spatial relationships in the replication of chromosomal DNA. Genetics 51:915-929
-
(1965)
Genetics
, vol.51
, pp. 915-929
-
-
Walen, K.H.1
-
25
-
-
0036118780
-
The origin of transformed cells: Studies of spontaneous and induced cell transformation in cell cultures from marsupials, a snail, and human amnio- cytes
-
Walen KH (2002) The origin of transformed cells: studies of spontaneous and induced cell transformation in cell cultures from marsupials, a snail, and human amnio- cytes. Cancer Genet Cytogenet 133:45-54
-
(2002)
Cancer Genet Cytogenet
, vol.133
, pp. 45-54
-
-
Walen, K.H.1
-
26
-
-
6044269353
-
Spontaneous cell transformation: Kary- oplasts derived from multinucleated cells produce new cell growth in senescent human epithelial cell cultures
-
Walen KH (2004) Spontaneous cell transformation: kary- oplasts derived from multinucleated cells produce new cell growth in senescent human epithelial cell cultures. In Vitro Cell Dev Biol Anim 40:150-158
-
(2004)
In Vitro Cell Dev Biol Anim
, vol.40
, pp. 150-158
-
-
Walen, K.H.1
-
27
-
-
28444499407
-
Budded karyoplasts from multinucle- ated fibroblast cells contain centrosome and change their morphology to mitotic cells
-
Walen KH (2005) Budded karyoplasts from multinucle- ated fibroblast cells contain centrosome and change their morphology to mitotic cells. Cell Biol Int 29:1057-1065
-
(2005)
Cell Biol Int
, vol.29
, pp. 1057-1065
-
-
Walen, K.H.1
-
28
-
-
33750585262
-
Human diploid fibroblast cells in senescence: Cycling through polyploidy to mitotic cells
-
Walen KH (2006) Human diploid fibroblast cells in senescence: cycling through polyploidy to mitotic cells. In Vitro Cell Dev Biol Anim 42:216-224
-
(2006)
In Vitro Cell Dev Biol Anim
, vol.42
, pp. 216-224
-
-
Walen, K.H.1
-
29
-
-
35349031702
-
Origin of diplochromosomal polyploidy in near-senescent fibroblast cultures: Heterochromatin, telomeres and chromosomal instability (CIN)
-
Walen KH (2007a) Origin of diplochromosomal polyploidy in near-senescent fibroblast cultures: heterochromatin, telomeres and chromosomal instability (CIN). Cell Biol Int 31:1447-1455
-
(2007)
Cell Biol Int
, vol.31
, pp. 1447-1455
-
-
Walen, K.H.1
-
30
-
-
33846618170
-
Bipolar genome reductional division of human near-senescent, polyploidy fibroblast cells
-
Walen KH (2007b) Bipolar genome reductional division of human near-senescent, polyploidy fibroblast cells. Cancer Genet Cytogenet 173:43-50
-
(2007)
Cancer Genet Cytogenet
, vol.173
, pp. 43-50
-
-
Walen, K.H.1
-
31
-
-
45849116227
-
Genetic stability of senescence reverted cells: Genome reduction division of polyploid cells, aneuploidy and neoplasia
-
Walen KH (2008) Genetic stability of senescence reverted cells: genome reduction division of polyploid cells, aneuploidy and neoplasia. Cell Cycle 7:1623-1629
-
(2008)
Cell Cycle
, vol.7
, pp. 1623-1629
-
-
Walen, K.H.1
-
32
-
-
77956122217
-
Mitosis is not the only distributor of mutated cells: Non-mitotic enopolyploid cells produce reproductive genome reduced cells
-
Walen KH (2010) Mitosis is not the only distributor of mutated cells: non-mitotic enopolyploid cells produce reproductive genome reduced cells. Cell Biol Int 34:867-872
-
(2010)
Cell Biol Int
, vol.34
, pp. 867-872
-
-
Walen, K.H.1
-
33
-
-
84859236487
-
Normal human cell conversion to 3-D cancer-like growth: Genome damage, endopolyploidy, senescence escape, and cell polarity change/loss
-
Walen KH (2011) Normal human cell conversion to 3-D cancer-like growth: genome damage, endopolyploidy, senescence escape, and cell polarity change/loss. J Cancer Ther 2:181-189
-
(2011)
J Cancer Ther
, vol.2
, pp. 181-189
-
-
Walen, K.H.1
-
34
-
-
84859254349
-
Genome reversion process of endopoly- ploidy confers chromosome instability on descendent diploid cells
-
Walen KH (2012) Genome reversion process of endopoly- ploidy confers chromosome instability on descendent diploid cells. Cell Biol Int 36:1-9
-
(2012)
Cell Biol Int
, vol.36
, pp. 1-9
-
-
Walen, K.H.1
-
35
-
-
64349123107
-
Autophagy mediates the mitotic senescence transition
-
Young ARJ, Narita M, Ferreira M, Kirschner K, Sadaie M, Darot JFJ, Tavare S, Arakawa S, Shimizu S, Watt FM, Narita M (2009) Autophagy mediates the mitotic senescence transition. Genes Dev 23:798-803
-
(2009)
Genes Dev
, vol.23
, pp. 798-803
-
-
Young, A.R.J.1
Narita, M.2
Ferreira, M.3
Kirschner, K.4
Sadaie, M.5
Darot, J.F.J.6
Tavare, S.7
Arakawa, S.8
Shimizu, S.9
Watt, F.M.10
Narita, M.11
|