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Volumn 43, Issue , 2017, Pages 147-155

Analysis of mitochondrial metabolism in situ: Combining stable isotope labeling with selective permeabilization

Author keywords

Cancer; Metabolism; Mitochondria; Permeabilization; Stable isotopes

Indexed keywords

DISEASES; ISOTOPES; MITOCHONDRIA; NEURODEGENERATIVE DISEASES; PHYSIOLOGY;

EID: 85009165596     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2016.12.005     Document Type: Article
Times cited : (30)

References (42)
  • 2
    • 84922448166 scopus 로고    scopus 로고
    • Methods and advances in metabolic flux analysis: a mini-review
    • Antoniewicz, M.R., Methods and advances in metabolic flux analysis: a mini-review. J. Ind. Microbiol. Biotechnol. 42 (2015), 317–325.
    • (2015) J. Ind. Microbiol. Biotechnol. , vol.42 , pp. 317-325
    • Antoniewicz, M.R.1
  • 5
    • 0031812898 scopus 로고    scopus 로고
    • Conformational stability of the N-terminal amino acid residues of mutated recombinant pigeon liver malic enzymes
    • Chou, W.Y., Huang, S.M., Chang, G.G., Conformational stability of the N-terminal amino acid residues of mutated recombinant pigeon liver malic enzymes. Protein Eng. 11 (1998), 371–376.
    • (1998) Protein Eng. , vol.11 , pp. 371-376
    • Chou, W.Y.1    Huang, S.M.2    Chang, G.G.3
  • 6
    • 84923888456 scopus 로고    scopus 로고
    • Isolation of mitochondria from tissue culture cells
    • (pdb.prot080002)
    • Clayton, D.A., Shadel, G.S., Isolation of mitochondria from tissue culture cells. Cold Spring Harb. Protoc., 2014, 2014 (pdb.prot080002).
    • (2014) Cold Spring Harb. Protoc. , vol.2014
    • Clayton, D.A.1    Shadel, G.S.2
  • 7
    • 34547680284 scopus 로고    scopus 로고
    • Structural and functional properties of isocitrate dehydrogenase from the psychrophilic bacterium desulfotalea psychrophila reveal a cold-active enzyme with an unusual high thermal stability
    • Fedøy, A.-E., Yang, N., Martinez, A., Leiros, H.-K.S., Steen, I.H., Structural and functional properties of isocitrate dehydrogenase from the psychrophilic bacterium desulfotalea psychrophila reveal a cold-active enzyme with an unusual high thermal stability. J. Mol. Biol. 372 (2007), 130–149.
    • (2007) J. Mol. Biol. , vol.372 , pp. 130-149
    • Fedøy, A.-E.1    Yang, N.2    Martinez, A.3    Leiros, H.-K.S.4    Steen, I.H.5
  • 9
    • 84971527083 scopus 로고    scopus 로고
    • Stable isotope tracer analysis in isolated mitochondria from mammalian systems
    • Gravel, S.-P., Andrzejewski, S., Avizonis, D., St-Pierre, J., Stable isotope tracer analysis in isolated mitochondria from mammalian systems. Metabolites 4 (2014), 166–183.
    • (2014) Metabolites , vol.4 , pp. 166-183
    • Gravel, S.-P.1    Andrzejewski, S.2    Avizonis, D.3    St-Pierre, J.4
  • 10
    • 0025238864 scopus 로고
    • Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the “top-down” approach of metabolic control theory
    • Hafner, R.P., Brown, G.C., Brand, M.D., Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the “top-down” approach of metabolic control theory. Eur. J. Biochem. 188 (1990), 313–319.
    • (1990) Eur. J. Biochem. , vol.188 , pp. 313-319
    • Hafner, R.P.1    Brown, G.C.2    Brand, M.D.3
  • 11
    • 0008688565 scopus 로고
    • Association of mitochondria with microtubules in cultured cells
    • Heggeness, M.H., Simon, M., Singer, S.J., Association of mitochondria with microtubules in cultured cells. Proc. Natl. Acad. Sci. USA 75 (1978), 3863–3866.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 3863-3866
    • Heggeness, M.H.1    Simon, M.2    Singer, S.J.3
  • 12
    • 66149088821 scopus 로고    scopus 로고
    • MetaboliteDetector: comprehensive analysis tool for targeted and nontargeted GC/MS based metabolome analysis
    • Hiller, K., Hangebrauk, J., Jäger, C., Spura, J., Schreiber, K., Schomburg, D., MetaboliteDetector: comprehensive analysis tool for targeted and nontargeted GC/MS based metabolome analysis. Anal. Chem. 81 (2009), 3429–3439.
    • (2009) Anal. Chem. , vol.81 , pp. 3429-3439
    • Hiller, K.1    Hangebrauk, J.2    Jäger, C.3    Spura, J.4    Schreiber, K.5    Schomburg, D.6
  • 13
    • 0017401484 scopus 로고
    • Control of respiration in isolated mitochondria: quantitative evaluation of the dependence of respiratory rates on [ATP], [ADP], and [Pi]
    • Holian, A., Owen, C.S., Wilson, D.F., Control of respiration in isolated mitochondria: quantitative evaluation of the dependence of respiratory rates on [ATP], [ADP], and [Pi]. Arch. Biochem. Biophys. 181 (1977), 164–171.
    • (1977) Arch. Biochem. Biophys. , vol.181 , pp. 164-171
    • Holian, A.1    Owen, C.S.2    Wilson, D.F.3
  • 15
    • 84859857964 scopus 로고    scopus 로고
    • Isotope labeling experiments in metabolomics and fluxomics
    • Klein, S., Heinzle, E., Isotope labeling experiments in metabolomics and fluxomics. Wiley Interdiscip. Rev. Syst. Biol. Med. 4 (2012), 261–272.
    • (2012) Wiley Interdiscip. Rev. Syst. Biol. Med. , vol.4 , pp. 261-272
    • Klein, S.1    Heinzle, E.2
  • 18
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • Lin, M.T., Beal, M.F., Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443 (2006), 787–795.
    • (2006) Nature , vol.443 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 21
    • 53049103850 scopus 로고    scopus 로고
    • Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer
    • Michelakis, E.D., Webster, L., Mackey, J.R., Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer. Br. J. Cancer 99 (2008), 989–994.
    • (2008) Br. J. Cancer , vol.99 , pp. 989-994
    • Michelakis, E.D.1    Webster, L.2    Mackey, J.R.3
  • 22
    • 0014010978 scopus 로고
    • Pyruvate carboxylase VII. A possible role for tightly bound manganese
    • Mildvan, A.S., Scrutton, M.C., Utter, M.F., Pyruvate carboxylase VII. A possible role for tightly bound manganese. J. Biol. Chem. 241 (1966), 3488–3498.
    • (1966) J. Biol. Chem. , vol.241 , pp. 3488-3498
    • Mildvan, A.S.1    Scrutton, M.C.2    Utter, M.F.3
  • 25
    • 58249093939 scopus 로고    scopus 로고
    • How mitochondria produce reactive oxygen species
    • Murphy, M.P., How mitochondria produce reactive oxygen species. Biochem. J. 417 (2009), 1–13.
    • (2009) Biochem. J. , vol.417 , pp. 1-13
    • Murphy, M.P.1
  • 26
    • 84943524817 scopus 로고    scopus 로고
    • Identification of active elementary flux modes in mitochondria using selectively permeabilized CHO cells
    • Nicolae, A., Wahrheit, J., Nonnenmacher, Y., Weyler, C., Heinzle, E., Identification of active elementary flux modes in mitochondria using selectively permeabilized CHO cells. Metab. Eng. 32 (2015), 95–105.
    • (2015) Metab. Eng. , vol.32 , pp. 95-105
    • Nicolae, A.1    Wahrheit, J.2    Nonnenmacher, Y.3    Weyler, C.4    Heinzle, E.5
  • 27
    • 84919338721 scopus 로고    scopus 로고
    • How to measure metabolic fluxes: a taxonomic guide for 13C fluxomics
    • Niedenführ, S., Wiechert, W., Nöh, K., How to measure metabolic fluxes: a taxonomic guide for 13C fluxomics. Curr. Opin. Biotechnol. 34 (2015), 82–90.
    • (2015) Curr. Opin. Biotechnol. , vol.34 , pp. 82-90
    • Niedenführ, S.1    Wiechert, W.2    Nöh, K.3
  • 28
    • 79951962628 scopus 로고    scopus 로고
    • Mitochondrial metabolite transport
    • Palmieri, F., Pierri, C.L., Mitochondrial metabolite transport. Essays Biochem. 47 (2010), 37–52.
    • (2010) Essays Biochem. , vol.47 , pp. 37-52
    • Palmieri, F.1    Pierri, C.L.2
  • 29
    • 79960712083 scopus 로고    scopus 로고
    • High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria
    • Rogers, G.W., Brand, M.D., Petrosyan, S., Ashok, D., Elorza, A.A., Ferrick, D.A., Murphy, A.N., High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria. PLOS ONE, 6, 2011, e21746.
    • (2011) PLOS ONE , vol.6 , pp. e21746
    • Rogers, G.W.1    Brand, M.D.2    Petrosyan, S.3    Ashok, D.4    Elorza, A.A.5    Ferrick, D.A.6    Murphy, A.N.7
  • 30
    • 84893226243 scopus 로고    scopus 로고
    • Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis
    • Salabei, J.K., Gibb, A.A., Hill, B.G., Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis. Nat. Protoc. 9 (2014), 421–438.
    • (2014) Nat. Protoc. , vol.9 , pp. 421-438
    • Salabei, J.K.1    Gibb, A.A.2    Hill, B.G.3
  • 31
    • 0025644869 scopus 로고
    • Permeabilizing cells: some methods and applications for the study of intracellular processes
    • Schulz, I., Permeabilizing cells: some methods and applications for the study of intracellular processes. Methods Enzymol. 192 (1990), 280–300.
    • (1990) Methods Enzymol. , vol.192 , pp. 280-300
    • Schulz, I.1
  • 32
    • 82355193801 scopus 로고    scopus 로고
    • Evaluation of respiration with clark type electrode in isolated mitochondria and permeabilized animal cells
    • C.M. Palmeira A.J. Moreno Humana Press
    • Silva, A., Oliveira, P., Evaluation of respiration with clark type electrode in isolated mitochondria and permeabilized animal cells. Palmeira, C.M., Moreno, A.J., (eds.) Mitochondrial Bioenergetics, 2012, Humana Press, 7–24.
    • (2012) Mitochondrial Bioenergetics , pp. 7-24
    • Silva, A.1    Oliveira, P.2
  • 33
    • 84975474583 scopus 로고    scopus 로고
    • Differential susceptibility of mitochondrial complex II to inhibition by oxaloacetate in brain and heart
    • Stepanova, A., Shurubor, Y., Valsecchi, F., Manfredi, G., Galkin, A., Differential susceptibility of mitochondrial complex II to inhibition by oxaloacetate in brain and heart. Biochim. Biophys. Acta BBA: Bioenerg. 1857 (2016), 1561–1568.
    • (2016) Biochim. Biophys. Acta BBA: Bioenerg. , vol.1857 , pp. 1561-1568
    • Stepanova, A.1    Shurubor, Y.2    Valsecchi, F.3    Manfredi, G.4    Galkin, A.5
  • 35
    • 84925146879 scopus 로고    scopus 로고
    • High-throughput respiration screening of single mitochondrial substrates using permeabilized CHO cells highlights control of mitochondria metabolism
    • Wahrheit, J., Nonnenmacher, Y., Sperber, S., Heinzle, E., High-throughput respiration screening of single mitochondrial substrates using permeabilized CHO cells highlights control of mitochondria metabolism. Eng. Life Sci. 15 (2015), 184–194.
    • (2015) Eng. Life Sci. , vol.15 , pp. 184-194
    • Wahrheit, J.1    Nonnenmacher, Y.2    Sperber, S.3    Heinzle, E.4
  • 36
    • 84894236997 scopus 로고    scopus 로고
    • Fragment formula calculator (FFC): determination of chemical formulas for fragment ions in mass spectrometric data
    • Wegner, A., Weindl, D., Jäger, C., Sapcariu, S.C., Dong, X., Stephanopoulos, G., Hiller, K., Fragment formula calculator (FFC): determination of chemical formulas for fragment ions in mass spectrometric data. Anal. Chem. 86 (2014), 2221–2228.
    • (2014) Anal. Chem. , vol.86 , pp. 2221-2228
    • Wegner, A.1    Weindl, D.2    Jäger, C.3    Sapcariu, S.C.4    Dong, X.5    Stephanopoulos, G.6    Hiller, K.7
  • 38
    • 0034741983 scopus 로고    scopus 로고
    • 13C metabolic flux analysis
    • Wiechert, W., 13C metabolic flux analysis. Metab. Eng. 3 (2001), 195–206.
    • (2001) Metab. Eng. , vol.3 , pp. 195-206
    • Wiechert, W.1
  • 39
    • 0004854859 scopus 로고
    • Regulation of the citric acid cycle in mammalian systems
    • Williamson, J.R., Cooper, R.H., Regulation of the citric acid cycle in mammalian systems. FEBS Lett. 117 (1980), K73–K85.
    • (1980) FEBS Lett. , vol.117 , pp. K73-K85
    • Williamson, J.R.1    Cooper, R.H.2
  • 40
    • 82355170972 scopus 로고    scopus 로고
    • Mitochondrial permeability transition pore and calcium handling
    • Wong, R., Steenbergen, C., Murphy, E., Mitochondrial permeability transition pore and calcium handling. Methods Mol. Biol. 810 (2012), 235–242.
    • (2012) Methods Mol. Biol. , vol.810 , pp. 235-242
    • Wong, R.1    Steenbergen, C.2    Murphy, E.3
  • 42
    • 70149093436 scopus 로고    scopus 로고
    • Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
    • Yao, J., Irwin, R.W., Zhao, L., Nilsen, J., Hamilton, R.T., Brinton, R.D., Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. USA 106 (2009), 14670–14675.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 14670-14675
    • Yao, J.1    Irwin, R.W.2    Zhao, L.3    Nilsen, J.4    Hamilton, R.T.5    Brinton, R.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.