Neurochemical differences in learning and memory paradigms among rats supplemented with anthocyanin-rich blueberry diets and exposed to acute doses of 56 Fe particles

Life Sciences in Space Research

Volumn 12, Issue , 2017, Pages 16-23

  Poulose, Shibu M ^a   Rabin, Bernard M ^b   Bielinski, Donna F ^a   Kelly, Megan E ^a   Miller, Marshall G ^a   Thanthaeng, Nopporn ^a   Shukitt Hale, Barbara ^a  

^a TUFTS UNIVERSITY   (United States)

^b UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

Author keywords

Blueberries; Hippocampus; Inflammation; Learning; Memory; Radiation

Indexed keywords

ANTHOCYANIN; CYCLOOXYGENASE 2; IRON; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; TRANSCRIPTION FACTOR NRF2; ANTIOXIDANT; NEUROPROTECTIVE AGENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BLUEBERRY; BRAIN REGION; COGNITION; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG MECHANISM; FRONTAL CORTEX; HIPPOCAMPUS; LEARNING; MALE; MEMORY; NEUROCHEMISTRY; NEUROPROTECTION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN CARBONYLATION; PROTEIN EXPRESSION; RADIATION EXPOSURE; RAT; ANIMAL; ANIMAL BEHAVIOR; CHEMISTRY; COSMIC RADIATION; DIET; DRUG EFFECTS; FRONTAL LOBE; OXIDATIVE STRESS; RADIATION RESPONSE; SPRAGUE DAWLEY RAT; VACCINIUM;

ANIMALS; ANTHOCYANINS; ANTIOXIDANTS; BEHAVIOR, ANIMAL; BLUEBERRY PLANTS; COSMIC RADIATION; DIET; FRONTAL LOBE; HIPPOCAMPUS; IRON RADIOISOTOPES; LEARNING; MALE; MEMORY; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 85008439797     PISSN: 22145524     EISSN: 22145532     Source Type: Journal    
DOI: 10.1016/j.lssr.2016.12.002     Document Type: Article

References (26)

1. Brieger, K., Schiavone, S., Miller, F.J. Jr., Krause, K.H., Reactive oxygen species: from health to disease. Swiss Med. Wkly., 142, 2012, w13659.
2. Britten, R.A., Davis, L.K., Johnson, A.M., Keeney, S., Siegel, A., Sanford, L.D., Singletary, S.J., Lonart, G., Low (20 cGy) doses of 1 GeV/u (56)Fe–particle radiation lead to a persistent reduction in the spatial learning ability of rats. Radiat. Res. 177 (2012), 146–151.
3. Cannizzo, E.S., Clement, C.C., Sahu, R., Follo, C., Santambrogio, L., Oxidative stress, inflamm-aging and immunosenescence. J. Proteom. 74 (2011), 2313–2323.
4. Choi, D.H., Kim, J.H., Lee, K.H., Kim, H.Y., Kim, Y.S., Choi, W.S., Lee, J., Role of neuronal NADPH oxidase 1 in the peri-infarct regions after stroke. PLoS One, 10, 2015, e0116814.
5. Coyoy, A., Olguin-Albuerne, M., Martinez-Briseno, P., Moran, J., Role of reactive oxygen species and NADPH-oxidase in the development of rat cerebellum. Neurochem. Int. 62 (2013), 998–1011.
6. Elks, C.M., Reed, S.D., Mariappan, N., Shukitt-Hale, B., Joseph, J.A., Ingram, D.K., Francis, J., A blueberry-enriched diet attenuates nephropathy in a rat model of hypertension via reduction in oxidative stress. PLoS One, 6, 2011, e24028.
7. Esteras, N., Dinkova-Kostova, A.T., Abramov, A.Y., Nrf2 activation in the treatment of neurodegenerative diseases: a focus on its role in mitochondrial bioenergetics and function. Biol. Chem. 397 (2016), 383–400.
8. Gkikas, I., Petratou, D., Tavernarakis, N., Longevity pathways and memory aging. Front. Genet., 5, 2014, 155, 10.3389/fgene.
9. Hellweg, C.E., Baumstark-Khan, C., Getting ready for the manned mission to Mars: the astronauts' risk from space radiation. Naturwissenschaften 94 (2007), 517–526.
10. Joseph, J.A., Shukitt-Hale, B., Willis, L.M., Grape juice, berries, and walnuts affect brain aging and behavior. J. Nutr. 139 (2009), 1813S–1817S.
11. Lau, F.C., Joseph, J.A., McDonald, J.E., Kalt, W., Attenuation of iNOS and COX2 by blueberry polyphenols is mediated through the suppression of NF-[kappa]B activation. J. Funct. Foods 1 (2009), 274–283.
12. Miller, M.G., Shukitt-Hale, B., Berry fruit enhances beneficial signaling in the brain. J. Agric. Food Chem. 60 (2012), 5709–5715.
13. Miller, S.L., Celone, K., DePeau, K., Diamond, E., Dickerson, B.C., Rentz, D., Pihlajamaki, M., Sperling, R.A., Age-related memory impairment associated with loss of parietal deactivation but preserved hippocampal activation. Proc. Natl. Acad. Sci. USA 105 (2008), 2181–2186.
14. Pedersen, J.T., Heegaard, N.H., Analysis of protein aggregation in neurodegenerative disease. Anal. Chem. 85 (2013), 4215–4227.
15. Poulose, S.M., Carey, A.N., Shukitt-Hale, B., 2012. Improving brain signaling in aging: could berries be the answer? Expert Rev. Neurother. 12, 887–9.
16. Poulose, S.M., Bielinski, D.F., Carrihill-Knoll, K.L., Rabin, B.M., Shukitt-Hale, B., Protective effects of blueberry-and strawberry diets on neuronal stress following exposure to 56 Fe particles. Brain Res. 1593 (2014), 9–18.
17. Poulose, S.M., Bielinski, D.F., Carey, A., Schauss, A.G., Shukitt-Hale, B., Modulation of oxidative stress, inflammation, autophagy and expression of Nrf2 in hippocampus and frontal cortex of rats fed with acai-enriched diets. Nutr. Neurosci., 2016, 10.1080/1028415X.2015.1125654.
18. Rabin, B.M., Poulose, S.M., Carrihill-Knoll, K.L., Ramirez, F., Bielinski, D.F., Heroux, N., Shukitt-Hale, B., Acute effects of exposure to (56)Fe and (16)O particles on learning and memory. Radiat. Res. 184 (2015), 143–150.
19. Rola, R., Otsuka, S., Obenaus, A., Nelson, G.A., Limoli, C.L., VandenBerg, S.R., Fike, J.R., Indicators of hippocampal neurogenesis are altered by 56Fe-particle irradiation in a dose-dependent manner. Radiat. Res. 162 (2004), 442–446.
20. Ross, C.A., Poirier, M.A., Protein aggregation and neurodegenerative disease. Nat. Med. 10 (2004), S10–S17 10 Suppl.
21. Shukitt-Hale, B., Carey, A.N., Jenkins, D., Rabin, B.M., Joseph, J.A., Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging. Neurobiol. Aging 28 (2007), 1187–1194.
22. Shukitt-Hale, B., Lau, F.C., Cheng, V., Luskin, K., Carey, A.N., Carrihill-Knoll, K., Rabin, B.M., Joseph, J.A., Changes in gene expression in the rat hippocampus following exposure to 56Fe particles and protection by berry diets. Cent. Nerv. Syst. Agents Med. Chem. 13 (2013), 36–42.
23. Tanase, M., Urbanska, A.M., Zolla, V., Clement, C.C., Huang, L., Morozova, K., Follo, C., Goldberg, M., Roda, B., Reschiglian, P., Santambrogio, L., Role of carbonyl modifications on aging-associated protein aggregation. Sci. Rep., 6, 2016, 19311.
24. Ungvari, Z., Kaley, G., de Cabo, R., Sonntag, W.E., Csiszar, A., Mechanisms of vascular aging: new perspectives. J. Gerontol. Ser. A, Biol. Sci. Med. Sci. 65 (2010), 1028–1041.
25. Wang, Y., Kan, H., Yin, Y., Wu, W., Hu, W., Wang, M., Li, W., Protective effects of ginsenoside Rg1 on chronic restraint stress induced learning and memory impairments in male mice. Pharmacol. Biochem. Behav. 120 (2014), 73–81.
26. Yasojima, K., Schwab, C., McGeer, E.G., McGeer, P.L., Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs. Brain. Res. 830 (1999), 226–236.