In vivo and in vitro evaluation of the effects of Urtica dioica and swimming activity on diabetic factors and pancreatic beta cells

BMC Complementary and Alternative Medicine

Volumn 16, Issue 1, 2016, Pages

  Ranjbari, Abbas ^a   Azarbayjani, Mohammad Ali ^b   Yusof, Ashril ^c   Mokhtar, Abdul Halim ^c   Akbarzadeh, Samad ^d   Ibrahim, Mohamed Yousif ^c   Tarverdizadeh, Bahman ^e   Farzadinia, Parviz ^d   Hajiaghaee, Reza ^f   Dehghan, Firouzeh ^c  

^a Farhangyan University   (Iran)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

^c UNIVERSITY OF MALAYA   (Malaysia)

^d BUSHEHR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e ISLAMIC AZAD UNIVERSITY   (Iran)

^f AVICENNA RESEARCH INSTITUTE   (Iran)

Author keywords

Cholesterol; Diabetes; Insulin resistance; Pancreatic islet beta cells; Swimming exercise; TG; Urtica dioica

Indexed keywords

CHOLESTEROL; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; METFORMIN; TRIACYLGLYCEROL; URTICA DIOICA EXTRACT; GLUCOSE; INSULIN; PLANT EXTRACT;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CELL DAMAGE; CELL REGENERATION; CELL VIABILITY ASSAY; CHEMICAL COMPOSITION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; MASS FRAGMENTOGRAPHY; METABOLIC PARAMETERS; MYOTUBE; NONHUMAN; PANCREAS ISLET BETA CELL; PLANT PARAMETERS; RANDOMIZED CONTROLLED TRIAL; RAT; SWIMMING; TRIACYLGLYCEROL BLOOD LEVEL; URTICA DIOICA; ANIMAL; CELL LINE; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; MULTIMODALITY CANCER THERAPY; PHYTOTHERAPY; WISTAR KYOTO RAT;

ANIMALS; CELL LINE; COMBINED MODALITY THERAPY; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE; INSULIN; INSULIN SECRETION; MALE; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, INBRED WKY; SWIMMING; URTICA DIOICA;

EID: 85008354827     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-016-1064-6     Document Type: Article

References (55)

1. Educators AAoD. Intensive diabetes management: implications of the DCCT and UKPDS. Diabetes Educ. 2002;28(5):735.
2. Erkelens DW. Insulin resistance syndrome and type 2 diabetes mellitus. Am J Cardiol. 2001;88(7):38-42.
3. Bloem CJ, Chang AM. Short-term exercise improves ß-cell function and insulin resistance in older people with impaired glucose tolerance. J Clin Endocrinol Metab. 2008;93(2):387-92.
4. Basciano H, Federico L, Adeli K. Fructose, insulin resistance, and metabolic dyslipidemia. Nutr Metab. 2005;2(1):5.
5. Poirier P, Tremblay A, Broderick TL, Catellier C, Tancrede G, Nadeau A. Impact of moderate aerobic exercise training on insulin sensitivity in type 2 diabetic men treated with oral hypoglycemic agents: is insulin sensitivity enhanced only in nonobese subjects? Signature. 2002;8(2):65.
6. Edwin E, Sheeja E, Gupta V, Jain D. Fight diabetes the herbal way. Express Pharma Rev. 2006;1:41-2.
7. Jarald E, Joshi SB, Jain DC. Diabetes and herbal medicines. Iran J Pharmacol Ther. 2008;7(1):97-106.
8. Anderson JW, Kendall CW, Jenkins DJ. Importance of weight management in type 2 diabetes: review with meta-analysis of clinical studies. J Am Coll Nutr. 2003;22(5):331-9.
9. Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract. 2010;87(1):4-14.
10. Roglic G, Unwin N. Mortality attributable to diabetes: estimates for the year Diabetes Res Clin Pract. 2010;87(1):15-9.
11. Zhaolan L, Chaowei F, Weibing W, Biao X. Prevalence of chronic complications of type 2 diabetes mellitus in outpatients-a correstional hospital based survey in urban China. HQLO. 2010;8:62-71.
12. Joshi SR, Das A, Vijay V, Mohan V. Challenges in diabetes care in India: sheer numbers, lack of awareness and inadequate control. J Assoc Physicians India. 2008;56:443-50.
13. Itokawa H, Morris-Natschke SL, Akiyama T, Lee K-H. Plant-derived natural product research aimed at new drug discovery. J Nat Med. 2008;62(3):263-80.
14. Sharma R. Effect of fenugreek seeds and leaves on blood glucose and serum insulin responses in human subjects. Nutr Res. 1986;6(12):1353-64.
15. Bnouham M, Merhfour F-Z, Ziyyat A, Mekhfi H, Aziz M, Legssyer A. Antihyperglycemic activity of the aqueous extract of Urtica dioica. Fitoterapia. 2003;74(7):677-81.
16. Mathieu C. Can we reduce hypoglycaemia with insulin detemir? Int J Obes. 2004;28:S35-40.
17. Hunt LM, Arar NH, Akana LL. Herbs, prayer, and insulin. Use of medical and alternative treatments by a group of Mexican American diabetes patients. J Fam Pract. 2000;49(3):216-23.
18. Arshadi S, Azarbayjani MA, Hajaghaalipor F, Yusof A, Peeri M, Bakhtiyari S, et al. Evaluation of Trigonella foenum-graecum extract in combination with swimming exercise compared to glibenclamide consumption on type 2 Diabetic rodents. Food Nutr Res. 2015;59.
19. Swanston-Flatt SK, Day C, Flatt PR, Gould B, Bailey C. Glycaemic effects of traditional European plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetes Res. 1989;10(2):69-73.
20. Roman RR, Alarcon-Aguilar F, Lara-Lemus A, Flores-Saenz J. Hypoglycemic effect of plants used in Mexico as antidiabetics. Arch Med Res. 1991;23(1):59-64.
21. Vavilova N. Homeopathic pharmacodynamics [in Russian], in 2 parts. Homeopathic Center, Smolensk, Everest, Moscow. 1994;2:208-11.
22. Durak I, Biri H, Devrim E, Sözen S, Avci A. Aqueous extract of Urtica dioica makes significant inhibition on adenosine deaminase activity in prostate tissue from patients with prostate cancer. Cancer Biol Ther. 2004;3(9):855-7.
23. Abdullin I, Turova E, Gaisina GK, Budnikov G. Use of electrogenerated bromine for estimating the total antioxidant capacity of plant raw materials and plant-based medicinal preparations. J Anal Chem. 2002;57(6):557-60.
24. Hadizadeh I, Peivastegan B, Kolahi M. Antifungal activity of nettle (Urtica dioica L.), colocynth (Citrullus colocynthis L. Schrad), oleander (Nerium oleander L.) and konar (Ziziphus spina-christi L.) extracts on plants pathogenic fungi. Pak J Biol Sci. 2009;12(1):58-63.
25. Dar SA, Yousuf A, Ganai FA, Sharma P, Kumar N, Singh R. Bioassay guided isolation and identification of anti-inflammatory and anti-microbial compounds from Urtica dioica L. (Urticaceae) leaves. Afr J Biotechnol. 2012;11(65):12910-20.
26. Kadan S, Saad B, Sasson Y, Zaid H. In vitro evaluations of cytotoxicity of eight antidiabetic medicinal plants and their effect on GLUT4 translocation. Evid Based Complement Alternat Med. 2013;549345(10):28.
27. Mehri A, Hasani-Ranjbar S, Larijani B, Abdollahi M. A systematic review of efficacy and safety of Urtica dioica in the treatment of diabetes. Int J Pharmacol. 2011;7(2):161-70.
28. Wagner H, Willer F, Samtleben R, Boos G. Search for the antiprostatic principle of stinging nettle (Urtica dioica) roots. Phytomedicine. 1994;1(3):213-24.
29. Otles S, Yalcin B. Phenolic compounds analysis of root, stalk, and leaves of nettle. Sci World J. 2012;2012.
30. Kavalali G, Tuncel H, Göksel S, Hatemi H. Hypoglycemic activity of Urtica pilulifera in streptozotocin-diabetic rats. J Ethnopharmacol. 2003;84(2):241-5.
31. Lopatkin N, Sivkov A, Schläfke S, Funk P, Medvedev A, Engelmann U. Efficacy and safety of a combination of Sabal and Urtica extract in lower urinary tract symptoms-long-term follow-up of a placebo-controlled, double-blind, multicenter trial. Int Urol Nephrol. 2007;39(4):1137-46.
32. Kayser K, Bubenzer J, Kayser G, Eichhorn S, Zemlyanukhina TV, Bovin NV, Andre S, Koopmann J, Gabius H-J. Expression of lectin, interleukin-2 and histopathologic blood group binding sites in prostate cancer and its correlation with integrated optical density and syntactic structure analysis. Anal Quant Cytol Histol. 1995;17(2):135-42.
33. Toldy A, Stadler K, Sasvári M, Jakus J, Jung KJ, Chung HY, Berkes I, Nyakas C, Radák Z. The effect of exercise and nettle supplementation on oxidative stress markers in the rat brain. Brain Res Bull. 2005;65(6):487-93.
34. Sigal RJ, Kenny GP, Wasserman DH, Castaneda-Sceppa C, White RD. Physical activity/exercise and type 2 diabetes a consensus statement from the American diabetes Association. Diabetes Care. 2006;29(6):1433-8.
35. Blair SN, Kohl HW, Paffenbarger RS, Clark DG, Cooper KH, Gibbons LW. Physical fitness and all-cause mortality: a prospective study of healthy men and women. Jama. 1989;262(17):2395-401.
36. Glaser NS, Kuppermann N, Yee CK, Schwartz DL, Styne DM. Variation in the management of pediatric diabetic ketoacidosis by specialty training. Arch Pediatr Adolesc Med. 1997;151(11):1125-32.
37. Ivy JL. The insulin-like effect of muscle contraction. Exerc Sport Sci Rev. 1986;15:29-51.
38. Rose AJ, Richter EA. Skeletal muscle glucose uptake during exercise: how is it regulated? Physiology. 2005;20(4):260-70.
39. Salmani M, Aalizadeh A, Moghimi S, Tarverdizadeh B, Akbarzadeh S, Ashtiyani SC, Azarbayjani MA: Studying the effects aqueous extract of Urtica dioica and swimming training on the histochemical properties of liver in diabetic rats. J Chem Pharma Res 2015;7(1)645-660.
40. Subash-Babu P, Ignacimuthu S, Alshatwi A. Nymphayol increases glucosestimulated insulin secretion by RIN-5 F cells and GLUT4-mediated insulin sensitization in type 2 diabetic rat liver. Chem Biol Interact. 2015;226:72-81.
41. Garber JC, Barbee R, Bielitzki JT, Clayton L, Donovan J, Hendriksen C, Kohn D, Lipman N, Locke P, Melcher J. Guide for the Care and use of Laboratory Animals, vol. 8. 2010.
42. Zamami Y, Takatori S, Goda M, Koyama T, Iwatani Y, Jin X, Takai-Doi S, Kawasaki H. Royal jelly ameliorates insulin resistance in fructose-drinking rats. Biol Pharm Bull. 2008;31(11):2103-7.
43. Dai C-Y, Huang J-F, Hsieh M-Y, Hou N-J, Lin Z-Y, Chen S-C, Hsieh M-Y, Wang L-Y, Chang W-Y, Chuang W-L. Insulin resistance predicts response to peginterferon-alpha/ribavirin combination therapy in chronic hepatitis C patients. J Hepatol. 2009;50(4):712-8.
44. Katz A, Nambi SS, Mather K, Baron AD, Follmann DA, Sullivan G, Quon MJ. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab. 2000;85(7):2402-10.
45. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18(6):499-502.
46. Das M, Sarma B, Rokeya B, Parial R, Nahar N, Mosihuzzaman M, Khan A, Ali L. Antihyperglycemic and antihyperlipidemic activity of Urtica dioica on type 2 diabetic model rats. J Diabetol. 2011;2(2):1-6.
47. Ziyyat A, Legssyer A, Mekhfi H, Dassouli A, Serhrouchni M, Benjelloun W. Phytotherapy of hypertension and diabetes in oriental Morocco. J Ethnopharmacol. 1997;58(1):45-54.
48. Golalipour M, Khori V, Ghafari S, GharraviAnneh M. Chronic effect of the hydroalcoholic extract of Urtica dioica on regeneration of ß-cells of hyperglycemic rats. Pak J Biol Sci. 2006;9(8):1482-5.
49. FATHI AF, Garjani A, Maleki N, RANJ DS. Study of the hypoglycemic activity of the hydroalcoholic extract of urtica dioica in normal and diabetic ratss. Pharm Sci. 2005;2(65):6.
50. Domola MS, Vu V, Robson-Doucette CA, Sweeney G, Wheeler MB. Insulin mimetics in Urtica dioica: structural and computational analyses of Urtica dioica extracts. Phytother Res. 2010;24(S2):S175-82.
51. Silveira RF, de Almeida Leme JAC, de Almeida CC, Junior RJG, Sibuya CY, de Mello MAR, Luciano E. Comparative effects of physical training and metformin in diabetic rats. Open Clin Chem J. 2008;1:13-6.
52. Association AD. Physical activity/exercise and diabetes. Diabetes Care. 2004;27:S58.
53. Tjønna AE, Lee SJ, Rognmo Ø, Stølen TO, Bye A, Haram PM, Loennechen JP, Al-Share QY, Skogvoll E, Slørdahl SA. Aerobic interval training versus continuous moderate exercise as a treatment for the metabolic syndrome a pilot study. Circulation. 2008;118(4):346-54.
54. Earnest CP. Exercise interval training: an improved stimulus for improving the physiology of pre-diabetes. Med Hypotheses. 2008;71(5):752-61.
55. Avci G, Kupeli E, Eryavuz A, Yesilada E, Kucukkurt I. Antihypercholesterolaemic and antioxidant activity assessment of some plants used as remedy in Turkish folk medicine. J Ethnopharmacol. 2006;107(3):418-23.