Antihypercholesterolaemic and antioxidant activity assessment of some plants used as remedy in Turkish folk medicine

Journal of Ethnopharmacology

Volumn 107, Issue 3, 2006, Pages 418-423

  Avci, Gulcan ^a   Kupeli, Esra ^b   Eryavuz, Abdullah ^a   Yesilada, Erdem ^c   Kucukkurt, Ismail ^a  

^a AFYON KOCATEPE UNIVERSITY   (Turkey)

^b GAZI UNIVERSITY   (Turkey)

^c YEDITEPE UNIVERSITY   (Turkey)

Author keywords

Agrostemma githago; Antihypercholesterolaemic effect; Antioxidant activity; Hypercholesterolaemia; Potentilla reptans; Thymbra spicata; Urtica dioica; Viscum album

Indexed keywords

AGROSTEMMA GITHAGO EXTRACT; ALANINE AMINOTRANSFERASE; ALCOHOL; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; NITRIC OXIDE; PLANT EXTRACT; POTENTILLA REPTANS EXTRACT; THYMBRA SPICATA EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; URTICA DIOICA EXTRACT; VISCUM ALBUM EXTRACT;

AGROSTEMMA GITHAGO; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AQUEOUS SOLUTION; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; DRUG ISOLATION; GLUCOSE BLOOD LEVEL; HYPERCHOLESTEROLEMIA; MALE; MOUSE; NONHUMAN; POTENTILLA REPTANS; STOMACH INJURY; THYMBRA SPICATA; TRADITIONAL MEDICINE; TRIACYLGLYCEROL BLOOD LEVEL; TURKEY (REPUBLIC); URTICA DIOICA; VISCUM ALBUM;

AGROSTEMMA; ALANINE TRANSAMINASE; ANIMALS; ANTICHOLESTEREMIC AGENTS; ANTIOXIDANTS; ASPARTATE AMINOTRANSFERASES; BLOOD GLUCOSE; CHOLESTEROL, DIETARY; HYPERCHOLESTEROLEMIA; LIPID PEROXIDATION; LIPIDS; MALE; MEDICINE, TRADITIONAL; MICE; NITRIC OXIDE; PLANT EXTRACTS; POTENTILLA; THYMUS PLANT; TURKEY; URTICA DIOICA; VISCUM ALBUM;

AGROSTEMMA GITHAGO; ANIMALIA; POTENTILLA REPTANS; THYMBRA SPICATA; URTICA DIOICA; VISCUM ALBUM;

EID: 33748419329     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2006.03.032     Document Type: Article

References (25)

1. Baser K.H.C., Honda G., and Mi{dotless}ki{dotless} W. Herb Drugs and Herbalists in Turkey (1986), Tokyo Publishing & Printing Co., Ltd., Tokyo
2. Case G.L., He L., Mo H., and Elson C.E. Induction of geranyl pyrophosphate pyrophosphatase activity by cholesterol-suppressive isoprenoids. Lipids 30 (1995) 357-359
3. Chang J.J., Chen T.H., Chan P., Chen Y.J., Hsu F.L., Lo M.Y., and Lin J.Y. The in vitro inhibitory effect of tannin derivatives on 3-hydroxy-3-methylglutaryl-coenzyme A reductase on vero cells. Pharmacology 62 (2001) 224-228
4. Child P., and Kuksis A. Critical role of ring rtructure in the differential uptake of cholesterol and plant sterols by membrane preparations in vitro. Journal of Lipid Research 24 (1983) 1196-1209
5. Child P., and Kuksis A. Investigation of the role of micellar phospholipid in the preferential uptake of cholesterol over sitosterol by dispersed rat jejunal villus cells. Biochemistry and Cell Biololgy 64 (1986) 847-853
6. Choe S., Kim H., Jeong T., Bok S., and Park Y. Naringin has an antiatherogenic effect with the inhibition of intercellular adhesion molecule-1 in hypercholesterolaemic rabbits. Cardiovascular Pharmacology 38 (2001) 947-955
7. Das S., Vasisht S., Das S.N., and Srivastava L.M. Correlation between total antioxidant status and lipid peroxidation in hypercholesterolaemia. Current Science 78 (2000) 486-487
8. Draper H.H., and Hardley M. Malondialdehyde determination as index of lipid peroxidation. Methods in Enzymology 186 (1990) 421-431
9. Hanci S., Sahin S., and Yilmaz L. Isolation of volatile oil from thyme (Thymbra spicata) by steam distillation. Nahrung 47 (2003) 252-255
10. Kang B.P.S., Mehta U., and Bansal M.P. Effect of diet induced hypercholesterolaemia and selenium supplementation on nitric oxide synthase activity. Archives of Physiology and Biochemistry 105 (1997) 603-606
11. 4-treated rats. Journal of Veterinary Medicine A 50 (2003) 264-268
12. Koracevic F., Koracevic G., Djordjevic V., Andrejevic S., and Cosic V. Method for the measurement of antioxidant activity in human fluids. Journal of Clinical Pathology 54 (2001) 356-361
13. Meguro S., Higashi K., Hase T., Honda Y., Otsuka A., Tokimitsu I., and Itakura H. Solubilization of phytosterols in diacylglycerol versus triacylglycerol improves the serum cholesterol-lowering effect. European Journal of Clinical Nutrition 55 (2001) 513-517
14. Miranda K.M., Espey M.G., and Wink D.A. A rapid simple spectrophotometric method for detection of nitrate and nitrite. Nitric Oxide 5 (2001) 62-71
15. Newall C.A., Anderson L.A., and Phillipson J.D. Herbal Medicines: A Guide for Health-Care Professionals (1996), The Pharmaceutical Press, London 263
16. Nofer J.R., Kehrel B., Fobker M., Levkau B., Assmann G., and von Eckardstein A. HDL and arteriosclerosis: beyond reverse cholesterol transport. Atherosclerosis 161 (2002) 1-16
17. Noyan, A. 1996. Lipid Metabolizmasi{dotless}. Yaşam ve Hekimlikte Fizyoloji. 8.baski{dotless}, Meteksan yayi{dotless}nlari{dotless}.
18. Orhan D.D., Aslan M., Sendogdu N., Ergun F., and Yesilada E. Evaluation of the hypoglycaemic effect and antioxidant activity of three Viscum album subspecies (European mistletoe) in streptozocin-diabetic rats. Journal of Ethnopharmacology 98 (2005) 95-102
19. Prasad K., and Kalra J. Oxygen free radicals and hypercholesterolaemic atherosclerosis: effect of Vitamin E. American Heart Journal 125 (1993) 958-973
20. Sidhu G.S., and Oakenfull D.G. A mechanism for the hypocholesterolaemic activity of saponins. British Journal of Nutrition 55 (1986) 643-649
21. Siepmann C., Bader G., Hiller K., Wray V., Domke T., and Nimtz M. New saponins from the seeds of Agrostemma githago var. githago. Planta Medica 64 (1998) 159-164
22. Southon S., Johnson I.T., Gee J.M., and Price K.R. The effect of Gypsophila saponins in the diet on mineral status and plasma cholesterol concentration in the rat. British Journal of Nutrition 59 (1988) 49-55
23. Szczeklik A., Gryglewski R.J., Domagala B., Dworski R., and Basista M. Dietary supplementation with Vitamin E in hyperlipoproteinemias: effects on plasma lipid peroxides, antioxidant activity, prostacyclin generation and platelet aggregability. Thrombosis and Haemostasis 54 (1985) 425-430
24. Turkdogan M.K., Ozbek H., Yener Z., Tuncer I., Uygan I., and Ceylan E. The role of Urtica dioica and Nigella sativa in the prevention of carbon tetrachloride-induced hepatotoxicity in rats. Phytotherapy Research 17 (2003) 942-946
25. Wagner H., Feil B., Seligmann O., Petricic J., and Kalogjera Z. Phenylpropanes and lignans of Viscum album cardioactive drugs V. Planta Medica 2 (1986) 102-104