Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumonia

BMC Genetics

Volumn 17, Issue 1, 2016, Pages

  Fingerlin, Tasha E ^a,b   Zhang, Weiming ^b   Yang, Ivana V ^c   Ainsworth, Hannah C ^d   Russell, Pamela H ^c   Blumhagen, Rachel Z ^a,b   Schwarz, Marvin I ^c   Brown, Kevin K ^a   Steele, Mark P ^e   Loyd, James E ^e   Cosgrove, Gregory P ^a   Lynch, David A ^a   Groshong, Steve ^a   Collard, Harold R ^f   Wolters, Paul J ^f   Bradford, Williamson Z ^g   Kossen, Karl ^g   Seiwert, Scott D ^g   Bois, Roland M ^h,i   Garcia, Christine Kim ^j   Devine, Megan S ^j   Gudmundsson, Gunnar ^k   Isaksson, Helgi J ^k   Kaminski, Naftali ^l   Zhang, Yingze ^l   Gibson, Kevin F ^l   Lancaster, Lisa H ^e   Maher, Toby M ^h,i   Molyneaux, Philip L ^h,i   Wells, Athol U ^h,i   Moffatt, Miriam F ^h,i   Selman, Moises ^m   Pardo, Annie ⁿ   Kim, Dong Soon ^o   Crapo, James D ^a   Make, Barry J ^a   Regan, Elizabeth A ^a   Walek, Dinesha S ^p   Daniel, Jerry J ^p   Kamatani, Yoichiro ^q   Zelenika, Diana ^r   Murphy, Elissa ^c   Smith, Keith ^c   McKean, David ^c   Pedersen, Brent S ^c   Talbert, Janet ^c   Powers, Julia ^c   Markin, Cheryl R ^e   Beckman, Kenneth B ^p   Lathrop, Mark ^q,r   Freed, Brian ^c   Langefeld, Carl D ^d   Schwartz, David A ^a,c   more..

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d WAKE FOREST SCHOOL OF MEDICINE   (United States)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g InterMune   (United States)

^h NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

ⁱ ROYAL BROMPTON HOSPITAL   (United Kingdom)

^j UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^k LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^l UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^m INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

ⁿ UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^o University of Ulsan College of Medicine   (South Korea)

^p UNIVERSITY OF MINNESOTA   (United States)

^q FONDATION JEAN DAUSSET CEPH   (France)

^r CENTRE NATIONAL DE GÉNOTYPAGE   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOIMMUNITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DQB1 GENE; FIBROTIC IDIOPATHIC INTERSTITIAL PNEUMONIA; GENE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE REPLICATION; GENETIC RECOMBINATION; GENETIC RISK; GENETIC VARIABILITY; HLA SYSTEM; HUMAN; HUMAN TISSUE; INTERSTITIAL PNEUMONIA; LUNG FIBROSIS; MAJOR CLINICAL STUDY; PROBABILITY; PROTEIN FOLDING; SINGLE NUCLEOTIDE POLYMORPHISM; VALIDATION PROCESS; ADULT; AGED; CHROMOSOME 6; FEMALE; FIBROSING ALVEOLITIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; MALE; MIDDLE AGED; PROCEDURES; SEQUENCE ANALYSIS;

HLA DQ ANTIGEN; HLA DRB1 ANTIGEN; HLA-DQB1 ANTIGEN;

ADULT; AGED; CHROMOSOMES, HUMAN, PAIR 6; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HLA-DQ BETA-CHAINS; HLA-DRB1 CHAINS; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; PULMONARY FIBROSIS; SEQUENCE ANALYSIS, RNA;

EID: 85008343470     PISSN: None     EISSN: 14712156     Source Type: Journal    
DOI: 10.1186/s12863-016-0377-2     Document Type: Article

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