Association of Human Leukocyte Antigen with Interstitial Lung Disease in Rheumatoid Arthritis: A protective role for shared epitope

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Furukawa, Hiroshi ^a   Oka, Shomi ^a   Shimada, Kota ^a,b   Sugii, Shoji ^a,b   Ohashi, Jun ^c   Matsui, Toshihiro ^a   Ikenaka, Tatsuoh ^a   Nakayama, Hisanori ^a   Hashimoto, Atsushi ^a   Takaoka, Hirokazu ^a   Arinuma, Yoshiyuki ^a   Okazaki, Yuko ^a   Futami, Hidekazu ^a   Komiya, Akiko ^a   Fukui, Naoshi ^a   Nakamura, Tadashi ^d   Migita, Kiyoshi ^e   Suda, Akiko ^f   Nagaoka, Shouhei ^f   Tsuchiya, Naoyuki ^c   Tohma, Shigeto ^a   more..

^a NATIONAL HOSPITAL ORGANIZATION   (Japan)

^b TOKYO METROPOLITAN TAMA MEDICAL CENTER   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d Kumamoto Center for Arthritis and Rheumatology   (Japan)

^e NATIONAL HOSPITAL ORGANIZATION NAGASAKI MEDICAL CENTER   (Japan)

^f Yokohama Minami Kyosai Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DPB1 ANTIGEN; HLA DQB1 ANTIGEN; HLA DR2 ANTIGEN; HLA DRB1 ANTIGEN; EPITOPE; HLA DP ANTIGEN; HLA DQ ANTIGEN; HLA-DPB1 ANTIGEN; HLA-DQB1 ANTIGEN; RHEUMATOID FACTOR;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC RISK; HLA DPB1 GENE; HLA DQB1 GENE; HLA DRB1 GENE; HUMAN; INTERSTITIAL LUNG DISEASE; JAPANESE; MAJOR CLINICAL STUDY; MALE; RHEUMATOID ARTHRITIS; RISK ASSESSMENT; SEROLOGY; BLOOD; GENE FREQUENCY; GENETICS; GENOTYPE; IMMUNOLOGY; JAPAN; MIDDLE AGED; RISK FACTOR;

AGED; ARTHRITIS, RHEUMATOID; EPITOPES; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENOTYPE; HLA-DP BETA-CHAINS; HLA-DQ BETA-CHAINS; HLA-DRB1 CHAINS; HUMANS; JAPAN; LUNG DISEASES, INTERSTITIAL; MALE; MIDDLE AGED; RHEUMATOID FACTOR; RISK FACTORS;

EID: 84860649671     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033133     Document Type: Article

References (26)

1. Perricone C, Ceccarelli F, Valesini G, (2011) An overview on the genetic of rheumatoid arthritis: a never-ending story. Autoimmun Rev 10 599-608. Epub 2011 Apr 2022.
2. Scott IC, Steer S, Lewis CM, Cope AP, (2011) Precipitating and perpetuating factors of rheumatoid arthritis immunopathology: linking the triad of genetic predisposition, environmental risk factors and autoimmunity to disease pathogenesis. Best Pract Res Clin Rheumatol 25: 447-468.
3. Lewis SN, Nsoesie E, Weeks C, Qiao D, Zhang L, (2011) Prediction of disease and phenotype associations from genome-wide association studies. PLoS ONE 6: e27175. Epub 22011 Nov 27174.
4. Reveille JD, (1998) The genetic contribution to the pathogenesis of rheumatoid arthritis. Curr Opin Rheumatol 10: 187-200.
5. Turesson C, Weyand CM, Matteson EL, (2004) Genetics of rheumatoid arthritis: Is there a pattern predicting extraarticular manifestations? Arthritis Rheum 51: 853-863.
6. Lanchbury JS, Jaeger EE, Sansom DM, Hall MA, Wordsworth P, et al. (1991) Strong primary selection for the Dw4 subtype of DR4 accounts for the HLA-DQw7 association with Felty's syndrome. Hum Immunol 32: 56-64.
7. Kim HY, Min JK, Yang HI, Park SH, Hong YS, et al. (1997) The impact of HLA-DRB1*0405 on disease severity in Korean patients with seropositive rheumatoid arthritis. Br J Rheumatol 36: 440-443.
8. Weyand CM, Xie C, Goronzy JJ, (1992) Homozygosity for the HLA-DRB1 allele selects for extraarticular manifestations in rheumatoid arthritis. J Clin Invest 89: 2033-2039.
9. Turesson C, Jacobsson LT, (2004) Epidemiology of extra-articular manifestations in rheumatoid arthritis. Scand J Rheumatol 33: 65-72.
10. Koduri G, Norton S, Young A, Cox N, Davies P, et al. (2010) Interstitial lung disease has a poor prognosis in rheumatoid arthritis: results from an inception cohort. Rheumatology 49: 1483-1489.
11. Migita K, Nakamura T, Koga T, Eguchi K, (2010) HLA-DRB1 alleles and rheumatoid arthritis-related pulmonary fibrosis. J Rheumatol 37: 205-207.
12. Shibue T, Tsuchiya N, Komata T, Matsushita M, Shiota M, et al. (2000) Tumor necrosis factor alpha 5′-flanking region, tumor necrosis factor receptor II, and HLA-DRB1 polymorphisms in Japanese patients with rheumatoid arthritis. Arthritis Rheum 43: 753-757.
13. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, et al. (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31: 315-324.
14. Webb WR, (2006) Thin-section CT of the secondary pulmonary lobule: anatomy and the image-the 2004 Fleischner lecture. Radiology 239: 322-338.
15. Stephens M, Donnelly P, (2003) A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet 73: 1162-1169. Epub 2003 Oct 1120.
16. Stephens M, Smith NJ, Donnelly P, (2001) A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 68: 978-989.
17. Ohashi J, Yamamoto S, Tsuchiya N, Hatta Y, Komata T, et al. (2001) Comparison of statistical power between 2 * 2 allele frequency and allele positivity tables in case-control studies of complex disease genes. Ann Hum Genet 65: 197-206.
18. DerSimonian R, Laird N, (1986) Meta-analysis in clinical trials. Control Clin Trials 7: 177-188.
19. Turesson C, Schaid DJ, Weyand CM, Jacobsson LT, Goronzy JJ, et al. (2005) The impact of HLA-DRB1 genes on extra-articular disease manifestations in rheumatoid arthritis. Arthritis Res Ther 7: R1386-1393.
20. Xue J, Gochuico BR, Alawad AS, Feghali-Bostwick CA, Noth I, et al. (2011) The HLA class II Allele DRB1*1501 is over-represented in patients with idiopathic pulmonary fibrosis. PLoS ONE 6: e14715.
21. Falfan-Valencia R, Camarena A, Juarez A, Becerril C, Montano M, et al. (2005) Major histocompatibility complex and alveolar epithelial apoptosis in idiopathic pulmonary fibrosis. Hum Genet 118: 235-244.
22. Sirikong M, Tsuchiya N, Chandanayingyong D, Bejrachandra S, Suthipinittharm P, et al. (2002) Association of HLA-DRB1*1502-DQB1*0501 haplotype with susceptibility to systemic lupus erythematosus in Thais. Tissue Antigens 59: 113-117.
23. Mattey DL, Gonzalez-Gay MA, Hajeer AH, Dababneh A, Thomson W, et al. (2000) Association between HLA-DRB1*15 and secondary Sjogren's syndrome in patients with rheumatoid arthritis. J Rheumatol 27: 2611-2616.
24. Tokunaga NK, Noda R, Kaneoka H, Ogahara S, Murata T, et al. (1999) Association between HLA-DRB1*15 and Japanese patients with rheumatoid arthritis complicated by renal involvement. Nephron 81: 165-171.
25. Wucherpfennig KW, Sette A, Southwood S, Oseroff C, Matsui M, et al. (1994) Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones. J Exp Med 179: 279-290.
26. Simeon CP, Fonollosa V, Tolosa C, Palou E, Selva A, et al. (2009) Association of HLA class II genes with systemic sclerosis in Spanish patients. J Rheumatol 36: 2733-2736.