Neuroanatomical features in soldiers with post-traumatic stress disorder

BMC Neuroscience

Volumn 17, Issue 1, 2016, Pages

  Sussman, D ^a   Pang, E W ^a   Jetly, R ^b   Dunkley, B T ^a   Taylor, M J ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b Institute of Mental Health Research   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANALYSIS OF VARIANCE; ARTICLE; BRAIN MAPPING; CAUDATE NUCLEUS; CEREBELLUM; CLINICAL ARTICLE; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; CORTICAL THICKNESS (BRAIN); GLOBUS PALLIDUS; GRAY MATTER; HIPPOCAMPUS; HUMAN; IMAGE ANALYSIS; IMAGE PROCESSING; IMAGE SEGMENTATION; MALE; NEUROANATOMY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; POSTTRAUMATIC STRESS DISORDER; PSYCHOMETRY; PUTAMEN; SOLDIER; THALAMUS; WHITE MATTER; BRAIN; INTELLIGENCE; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; PATHOLOGY; PSYCHOLOGY;

ADULT; BRAIN; HUMANS; INTELLIGENCE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MILITARY PERSONNEL; NEUROPSYCHOLOGICAL TESTS; STRESS DISORDERS, POST-TRAUMATIC;

EID: 85008325033     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/s12868-016-0247-x     Document Type: Article

References (62)

1. Adamaszek M, D'Agata F, Kirkby K, Trennert M, Sehm B, Steele C, Berneiser J, Strecker K. Impairment of emotional facial expression and prosody discrimination due to ischemic cerebellar lesions. Cerebellum. 2014;13:338-45.
2. Benjamini Y, Yekutieli D. The control of the false discovery rate in multiple testing under dependency. Ann Stat. 2001;29(4):1165-88
3. Bonne O, Brandes D, Gilboa A, Gomori JM, Shenton ME, Pitman RK, Shalev AY. Longitudinal MRI study of hippocampal volume in trauma survivors with PTSD. Am J Psychiatry. 2001;158(8):1248-51.
4. Braun AR, Guillemin A, Hosey L, Varga M. The neural organization of discourse. Brain. 2001;124(10):2028-44.
5. Bremner JD. Hypotheses and controversies related to effects of stress on the hippocampus: an argument for stress-induced damage to the hippocampus in patients with posttraumatic stress disorder. Hippocampus. 2001;11(2):75-81. doi:10.1002/hipo.1023
6. Breslau N, Lucia VC, Alvarado GF. Intelligence and other predisposing factors in exposure to trauma and posttraumatic stress disorder: a follow-up study at age 17 years. Arch Gen Psychiatry. 2006;63:1238-45.
7. Chakravarty MM, Steadman P, van Eede MC, Calcott RD, Gu V, Shaw P, Raznahan A, Collins DL, Lerch JP. Performing label-fusion-based segmentation using multiple automatically generated templates. Hum Brain Mapp. 2013;34(10):2635-54.
8. Chen S, Xia W, Li L, Liu J, He Z, Zhang Z, Yan L, Zhang J, Hu D. Gray matter density reduction in the insula in fire survivors with posttraumatic stress disorder: a voxel-based morphometric study. Psychiatry Res. 2006;146(1):65-72.
9. Chenn A, Walsh CA. Regulation of cerebral cortical size by control of cell cycle exit in neural precursors. Science (New York, N.Y.). 2002;297(5580):365-9.
10. Chung YA, Kim SH, Chung SK, Chae J-H, Yang DW, Sohn HS, Jeong J. Alterations in cerebral perfusion in posttraumatic stress disorder patients without re-exposure to accident-related stimuli. Clin Neurophysiol. 2006;117(3):637-42.
11. Clark CR, McFarlane AC, Morris P, Weber DL, Sonkkilla C, Shaw M, Marcina J, Tochon-Danguy HJ, Egan GF. Cerebral function in posttraumatic stress disorder during verbal working memory updating: a positron emission tomography study. Biol Psychiatry. 2003;53(6):474-81.
12. Collins DL, Holmes CJ, Peters TM, Evans AC. Automatic 3-D model-based neuroanatomical segmentation. Hum Brain Mapp. 1995;3(3):190-208.
13. Collins DL, Pruessner JC. Towards accurate, automatic segmentation of the hippocampus and amygdala from MRI by augmenting animal with a template library and label fusion. NeuroImage. 2010;52(4):1355-66.
14. Corbetta M, Patel G, Shulman GL. The reorienting system of the human brain: from environment to theory of mind. Neuron. 2008;58(3):306-24.
15. Critchley HD, Corfield DR, Chandler MP, Mathias CJ, Dolan RJ. Cerebral correlates of autonomic cardiovascular arousal: a functional neuroimaging investigation in humans. J Physiol. 2000;523(Pt 1):259-70.
16. De Bellis MD, Kuchibhatla M. Cerebellar volumes in pediatric maltreatment-related posttraumatic stress disorder. Biol Psychiatry. 2006;60(7):697-703.
17. Driessen M, Beblo T, Mertens M, Piefke M, Rullkoetter N, Silva-Saavedra A, Reddemann L, Rau H, Markowitsch HJ, Wulff H, Lange W, Woermann FG. Posttraumatic stress disorder and fMRI activation patterns of traumatic memory in patients with borderline personality disorder. Biol Psychiatry. 2004;55(6):603-11.
18. Elman I, Lowen S, Frederick BB, Chi W, Becerra L, Pitman RK. Functional neuroimaging of reward circuitry responsivity to monetary gains and losses in posttraumatic stress disorder. Biol Psychiatry. 2009;66(12):1083-90.
19. Fennema-Notestine C, Stein MB, Kennedy CM, Archibald SL, Jernigan TL. Brain morphometry in female victims of intimate partner violence with and without posttraumatic stress disorder. Biol Psychiatry. 2002;52(11):1089-101.
20. Fernandez M, Pissiota A, Frans O, von Knorring L, Fischer H, Fredrikson M. Brain function in a patient with torture related post-traumatic stress disorder before and after fluoxetine treatment: a positron emission tomography provocation study. Neurosci Lett. 2001;297(2):101-4.
21. Filipovic BR, Djurovic B, Marinkovic S, Stijak L, Aksic M, Nikolic V, et al. Volume changes of corpus striatum, thalamus, hippocampus and lateral ventricles in posttraumatic stress disorder (PTSD) patients suffering from headaches and without therapy. Cent Eur Neurosurg. 2011;72:133-7.
22. Geuze E, Westenberg HGM, Heinecke A, de Kloet CS, Goebel R, Vermetten E. Thinner prefrontal cortex in veterans with posttraumatic stress disorder. NeuroImage. 2008;41(3):675-81.
23. Gilbertson MW, Shenton ME, Ciszewski A, Kasai K, Lasko NB, Orr SP, Pitman RK. Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma. Nat Neurosci. 2002;5(11):1242-7.
24. Gurvits TV, Shenton ME, Hokama H, Ohta H, Lasko NB, Gilbertson MW, Orr SP, Kikinis R, Jolesz FA, McCarley RW, Pitman RK. Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder. Biol Psychiatry. 1996;40(11):1091-9.
25. Herringa R, Phillips M, Almeida J, Insana S, Germain A. Post-traumatic stress symptoms correlate with smaller subgenual cingulate, caudate, and insula volumes in unmedicated combat veterans. Psychiatry Res. 2012;203(2-3):139-45.
26. Jatzko A, Rothenhofer S, Schmitt A, Gaser C, Demirakca T, Weber-Fahr W, Wessa M, Magnotta V, Braus DF. Hippocampal volume in chronic posttraumatic stress disorder (PTSD): MRI study using two different evaluation methods. J Affect Disord. 2006;94(1-3):121-6.
27. Johansen-Berg H, Behrens TEJ. Diffusion MRI: from quantitative measurement to in vivo neuroanatomy. New York: Academic Press; 2009.
28. Kabani N, Le Goualher G, MacDonald D, Evans AC. Measurement of cortical thickness using an automated 3-D algorithm: a validation study. NeuroImage. 2001;13(2):375-80.
29. Karl A, Schaefer M, Malta LS, Dorfel D, Rohleder N, Werner A. A metaanalysis of structural brain abnormalities in PTSD. Neurosci Biobehav Rev. 2006;30(7):1004-31.
30. Kasai K, et al. Evidence for acquired pregenual anterior cingulate gray matter loss from a twin study of combat-related posttraumatic stress disorder. Biol Psychiatry. 2008;63:550-6.
31. Kim JS, Singh V, Lee JK, Lerch J, Ad-Dab'bagh Y, MacDonald D, Lee JM, Kim SI, Evans AC. Automated 3-d extraction and evaluation of the inner and outer cortical surfaces using a Laplacian map and partial volume effect classification. NeuroImage. 2005;27(1):210-21.
32. Kitayama N, Vaccarino V, Kutner M, Weiss P, Bremner JD. Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: a meta-analysis. J Affect Disord. 2005;88(1):79-86.
33. Kroes MCW, Rugg MD, Whalley MG, Brewin CR. Structural brain abnormalities common to posttraumatic stress disorder and depression. J Psychiatry Neurosci. 2011;36(4):256-65.
34. Lerch JP, Evans AC. Cortical thickness analysis examined through power analysis and a population simulation. NeuroImage. 2005;24(1):163-73.
35. Levy-Gigi E, Szabo C, Richter-Levin G, Kéri S. Reduced hippocampal volume is associated with overgeneralization of negative context in individuals with PTSD. Neuropsychology. 2014;29(1):151-61. doi:10.1037/ neu0000131.
36. Liberzon I, Sripada CS. Stress hormones and post traumatic stress disorder basic studies and clinical perspectives. In: Progress in brain research, vol. 167. Elsevier; 2007. doi:10.1016/S0079-6123(07)67011-3.
37. Margolis A, Bansal R, Hao X, Algermissen M, Erickson C, Klahr KW, Naglieri JA, Peterson BS. Using IQ discrepancy scores to examine the neural correlates of specific cognitive abilities. J Neurosci. 2013;33(35):14135-45.
38. Mueller-Pfeiffer C, Schick M, Schulte-Vels T, O'Gorman R, Michels L, Martin-Soelch C, Blair JR, Rufer M, Schnyder U, Zeffiro T, Hasler G. Atypical visual processing in posttraumatic stress disorder. NeuroImage Clin. 2013;3:531-8.
39. Pederson CL, Maurer SH, Kaminski PL, Zander KA, Peters CM, Stokes- Crowe LA, Osborn RE. Hippocampal volume and memory performance in a community-based sample of women with posttraumatic stress disorder secondary to child abuse. J Trauma Stress. 2004;17(1):37-40.
40. Pitman R, Rasmusson A, Koenen K, Shin L, Orr S, Gilbertson M, Milad M, Liberzon I. Biological studies of post-traumatic stress disorder. Nat Rev Neurosci. 2012;13:769-87.
41. Pizzagalli DA, Holmes AJ, Dillon DG, Goetz EL, Birk JL, Bogdan R, Dougherty DD, Iosifescu DV, Rauch SL, Fava M. Reduced caudate and nucleus accumbens response to rewards in unmedicated individuals with major depressive disorder. Am J Psychiatry. 2009;166(6):702-10.
42. Pontious A, Kowalczyk T, Englund C, Hevner RF. Role of intermediate progenitor cells in cerebral cortex development. Dev Neurosci. 2008;30(1-3):24-32.
43. Sailer U, Robinson S, Fischmeister FPS, König D, Oppenauer C, Lueger- Schuster B, Moser E, Kryspin-Exner I, Bauer H. Altered reward processing in the nucleus accumbens and mesial prefrontal cortex of patients with posttraumatic stress disorder. Neuropsychologia. 2008;46(11):2836-44.
44. Saltzman KM, Weems CF, Carrion VG. IQ and posttraumatic stress symptoms in children exposed to interpersonal violence. Child Psychiatry Hum Dev. 2006;36(3):261-72.
45. Schmidt U, Kaltwasser SF, Wotjak CT. Biomarkers in posttraumatic stress disorder: overview and implications for future research. Dis Markers. 2013;35(1):43-54.
46. Schuff N, Zhang Y, Zhan W, Lenoci M, Ching C, Boreta L, Mueller SG, Wang Z, Marmar CR, Weiner MW, Neylan TC. Patterns of altered cortical perfusion and diminished subcortical integrity in posttraumatic stress disorder: an MRI study. NeuroImage. 2011;54(Suppl 1):S62-8.
47. Shaw P, Greenstein D, Lerch J, Clasen L, Lenroot R, Gogtay N, Evans A, Rapoport J, Giedd J. Intellectual ability and cortical development in children and adolescents. Nature. 2006;440(7084):676-9.
48. Sherin JE, Nemeroff CB. Post-traumatic stress disorder: the neurobiological impact of psychological trauma. Dialogues Clin Neurosci. 2011;13(3):263-78.
49. Shin LM, Liberzon I. The neurocircuitry of fear, stress, and anxiety disorders. Neuropsychopharmacology. 2010;35(1):169-91.
50. Sled JG, Zijdenbos AP, Evans AC. A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Trans Med Imaging. 1998;17(1):87-97.
51. Sui SG, Zhang Y, Wu MX, Xu JM, Duan L, Weng XC, Shan BC, Li LJ. Abnormal cerebellum density in victims of rape with post-traumatic stress disorder: voxel-based analysis of magnetic resonance imaging investigation. Asia-Pac Psychiatry. 2010;2:129-35.
52. Tanielian T, Jaycox LH, Adamson DM, Burnam MA, Burns RM, Caldarone LB, Cox RA, D'Amico EJ, Diaz C, Eibner C, Fisher G, Helmus TC, Karney BR, Kilmer B, Marshall GN, Martin LT, Meredith LS, Metscher KN, Osilla KC, Pacula RL, Ramchand R, Ringel JS, Schell TL, Sollinger JM, Vaiana ME, Williams KM, Yochelson MR. Invisible wounds of war: psychological and cognitive injuries, their consequences, and services to assist recovery. Santa Monica: RAND Corporation; 2008. http://www.rand.org/pubs/ monographs/MG720.html.
53. Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, Mazoyer B, Joliot M. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. NeuroImage. 2002;15(1):273-89.
54. Vythilingam M, Nelson EE, Scaramozza M, Waldeck T, Hazlett G, Southwick SM, Pine DS, Drevets W, Charney DS, Ernst M. Reward circuitry in resilience to severe trauma: an fMRI investigation of resilient special forces soldiers. Psychiatry Res. 2009;172(1):75-7.
55. Weber DL, Clark CR, McFarlane AC, Moores KA, Morris P, Egan GF. Abnormal frontal and parietal activity during working memory updating in post-traumatic stress disorder. Psychiatry Res. 2005;140(1):27-44.
56. Winter H, Irle E. Hippocampal volume in adult burn patients with and without posttraumatic stress disorder. Am J Psychiatry. 2004;161(12):2194-200.
57. Yamasue H, Kasai K, Iwanami A, Ohtani T, Yamada H, Abe O, Kuroki N, Fukuda R, Tochigi M, Furukawa S, Sadamatsu M, Sasaki T, Aoki S, Ohtomo K, Asukai N, Kato N. Voxel-based analysis of MRI reveals anterior cingulate gray-matter volume reduction in posttraumatic stress disorder due to terrorism. Proc Natl Acad Sci USA. 2003;100(15):9039-43.
58. Yehuda R. Are glucocortoids responsible for putative hippocampal damage in PTSD How and when to decide. Hippocampus. 2001;11(2):85-9. doi:10.1002/hipo.1025
59. Yehuda R. Post-traumatic stress disorder. N Engl J Med. 2002;346(2):108-14.
60. Yehuda R, Golier JA, Tischler L, Stavitsky K, Harvey PD. Learning and memory in aging combat veterans with PTSD. J Clin Exp Neuropsychol. 2005;27(4):504-15.
61. Yehuda R, Hoge CW, McFarlane AC, Vermetten E, Lanius RA, Nievergelt CM, et al. Post-traumatic stress disorder. Nat Rev Dis Primers. 2015. doi:10.1038/nrdp.2015.57.
62. Zijdenbos AP, Forghani R, Evans AC. Automatic "pipeline" analysis of 3-D MRI data for clinical trials: application to multiple sclerosis. IEEE Trans Med Imaging. 2002;21(10):1280-91.