Genetic Obesity and the Risk of Atrial Fibrillation: Causal Estimates from Mendelian Randomization

Circulation

Volumn 135, Issue 8, 2017, Pages 741-754

  Chatterjee, Neal A ^a   Giulianini, Franco ^a   Geelhoed, Bastiaan ^b   Lunetta, Kathryn L ^c,d   Misialek, Jeffrey R ^e   Niemeijer, Maartje N ^f   Rienstra, Michiel ^m   Rose, Lynda M ^a   Smith, Albert V ^g   Arking, Dan E ^h   Ellinor, Patrick T ^i,j   Heeringa, Jan ^f   Lin, Honghuang ^c,d   Lubitz, Steven A ^i,j   Soliman, Elsayed Z ^k   Verweij, Niek ^b   Alonso, Alvaro ^l   Benjamin, Emelia J ^c,d   Gudnason, Vilmundur ^g   Stricker, Bruno H C ^f   Van Der Harst, Pim ^b   Chasman, Daniel I ^m   Albert, Christine M ^a   more..

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c FRAMINGHAM HEART STUDY   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF MINNESOTA   (United States)

^f ERASMUS MEDICAL CENTER   (Netherlands)

^g UNIVERSITY OF ICELAND   (Iceland)

^h JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ MASSACHUSETTS GENERAL HOSPITAL   (United States)

^j BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^k WAKE FOREST SCHOOL OF MEDICINE   (United States)

^l EMORY UNIVERSITY   (United States)

^m Emory University ^*

more..

Author keywords

atrial fibrillation; epidemiology; genetics; obesity; prevention control

Indexed keywords

ADULT; AGED; ARTICLE; ATRIAL FIBRILLATION; BODY MASS; BODY MASS INDEX GENE SCORE; CARDIOVASCULAR RISK; COHORT ANALYSIS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; ELECTROCARDIOGRAPHY; EUROPEAN; FEMALE; FTO GENE; GENE; GENE FREQUENCY; GENETIC CODE; GENETIC HETEROGENEITY; GENETIC VARIABILITY; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HEART FAILURE; HUMAN; HYPERTENSION; ICD-10; ICD-9-CM; ICELAND; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MENDELIAN RANDOMIZATION ANALYSIS; MULTICENTER STUDY; NETHERLANDS; OBESITY; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED STATES; ALLELE; GENETICS; META ANALYSIS; MIDDLE AGED; PATHOLOGY; PROPORTIONAL HAZARDS MODEL; RANDOMIZATION; RISK FACTOR;

ALPHA KETOGLUTARATE DEPENDENT DIOXYGENASE FTO; FTO PROTEIN, HUMAN;

AGED; ALLELES; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO; ATRIAL FIBRILLATION; BODY MASS INDEX; COHORT STUDIES; FEMALE; GENOTYPE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RANDOM ALLOCATION; RISK FACTORS;

EID: 85008313658     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.116.024921     Document Type: Article

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