Genetic variants related to height and risk of atrial fibrillation

American Journal of Epidemiology

Volumn 180, Issue 2, 2014, Pages 215-222

  Rosenberg, Michael A ^a   Kaplan, Robert C ^a   Siscovick, David S ^a   Psaty, Bruce M ^a   Heckbert, Susan R ^a   Newton Cheh, Christopher ^a   Mukamal, Kenneth J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

atrial fibrillation; cardiovascular disease; genetics; risk factors; risk prediction

Indexed keywords

CARDIOVASCULAR DISEASE; GENETIC VARIATION; HEIGHT; NUMERICAL MODEL; PHENOTYPE; POLYMORPHISM; PREDICTION; RISK FACTOR;

AGED; ALLELE; ARTICLE; CARDIOVASCULAR RISK; FEMALE; FOLLOW UP; GENETIC VARIABILITY; HEART ATRIUM FIBRILLATION; HEIGHT; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM;

ATRIAL FIBRILLATION; CARDIOVASCULAR DISEASE; GENETICS; RISK FACTORS; RISK PREDICTION;

AFRICAN AMERICANS; AGED; ATRIAL FIBRILLATION; BODY HEIGHT; ENDONUCLEASES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LONGITUDINAL STUDIES; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROPORTIONAL HAZARDS MODELS; RISK FACTORS;

EID: 84903989963     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kwu126     Document Type: Article

References (48)

1. Majeed A, Moser K, Carroll K. Trends in the prevalence and management of atrial fibrillation in general practice in England and Wales, 1994-1998: analysis of data from the General Practice Research Database. Heart. 2001;86(3): 284-288.
2. Go AS, Hylek EM, Phillips KA, et al. Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) study. JAMA. 2001; 285(18):2370-2375.
3. Darbar D, Herron KJ, Ballew JD, et al. Familial atrial fibrillation is a genetically heterogeneous disorder. J Am Coll Cardiol. 2003;41(12):2185-2192.
4. Fox CS, Parise H, D'Agostino RB Sr, et al. Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring. JAMA. 2004;291(23):2851-2855.
5. Ellinor PT, Yoerger DM, Ruskin JN, et al. Familial aggregation in lone atrial fibrillation. Hum Genet. 2005;118(2): 179-184.
6. Patton KK, Zacks ES, Chang JY, et al. Clinical subtypes of lone atrial fibrillation. Pacing Clin Electrophysiol. 2005;28(7): 630-638.
7. Hong K, Bjerregaard P, Gussak I, et al. Short QT syndrome and atrial fibrillation caused by mutation in KCNH2. J Cardiovasc Electrophysiol. 2005;16(4):394-396.
8. Xia M, Jin Q, Bendahhou S, et al. A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation. Biochem Biophys Res Commun. 2005;332(4):1012-1019.
9. Olson TM, Alekseev AE, Liu XK, et al. Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillation. Hum Mol Genet. 2006;15(14):2185-2191.
10. Fatini C, Sticchi E, Genuardi M, et al. Analysis of minK and eNOS genes as candidate loci for predisposition to non-valvular atrial fibrillation. Eur Heart J. 2006;27(14):1712-1718.
11. Fatini C, Sticchi E, Gensini F, et al. Lone and secondary nonvalvular atrial fibrillation: role of a genetic susceptibility. Int J Cardiol. 2007;120(1):59-65.
12. Kato K, Oguri M, Hibino T, et al. Genetic factors for lone atrial fibrillation. Int J Mol Med. 2007;19(6):933-939.
13. Nattel S, Shiroshita-Takeshita A, Cardin S, et al. Mechanisms of atrial remodeling and clinical relevance. Curr Opin Cardiol. 2005;20(1):21-25.
14. Ellinor PT, Lunetta KL, Albert CM, et al. Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet. 2012;44(6):670-675.
15. Teslovich TM, Musunuru K, Smith AV, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010;466(7307):707- 713.
16. Rosenberg MA, Patton KK, Sotoodehnia N, et al. The impact of height on the risk of atrial fibrillation: the Cardiovascular Health Study. Eur Heart J. 2012;33(21):2709-2717.
17. Chamberlain AM, Agarwal SK, Folsom AR, et al. A clinical risk score for atrial fibrillation in a biracial prospective cohort (from the Atherosclerosis Risk in Communities [ARIC] study). Am J Cardiol. 2011;107(1):85-91.
18. Schnabel RB, Sullivan LM, Levy D, et al. Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study. Lancet. 2009;373(9665): 739-745.
19. Suzuki S, Yamashita T, Ohtsuka T, et al. Body size and atrial fibrillation in Japanese outpatients. Circ J. 2010;74(1): 66-70.
20. Hanna IR, Heeke B, Bush H, et al. The relationship between stature and the prevalence of atrial fibrillation in patients with left ventricular dysfunction. J Am Coll Cardiol. 2006;47(8): 1683-1688.
21. Rosengren A, Hauptman PJ, Lappas G, et al. Big men and atrial fibrillation: effects of body size and weight gain on risk of atrial fibrillation in men. Eur Heart J. 2009;30(9): 1113-1120.
22. Mont L, Tamborero D, Elosua R, et al. Physical activity, height, and left atrial size are independent risk factors for lone atrial fibrillation in middle-aged healthy individuals. Europace. 2008;10(1):15-20.
23. Long MJ, Jiang CQ, Lam TH, et al. Atrial fibrillation and obesity among older Chinese: the Guangzhou Biobank Cohort Study. Int J Cardiol. 2011;148(1):48-52.
24. Psaty BM, Manolio TA, Kuller LH, et al. Incidence of and risk factors for atrial fibrillation in older adults. Circulation. 1997; 96(7):2455-2461.
25. Gudbjartsson DF, Arnar DO, Helgadottir A, et al. Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature. 2007;448(7151):353-357.
26. Benjamin EJ, Rice KM, Arking DE, et al. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet. 2009;41(8):879-881.
27. Conen D, Tedrow UB, Cook NR, et al. Birth weight is a significant risk factor for incident atrial fibrillation. Circulation. 2010;122(8):764-770.
28. Weedon MN, Lettre G, Freathy RM, et al. A common variant of HMGA2 is associated with adult and childhood height in the general population. Nat Genet. 2007;39(10): 1245-1250.
29. Lettre G, Jackson AU, Gieger C, et al. Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet. 2008;40(5):584-591.
30. Weedon MN, Lango H, Lindgren CM, et al. Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet. 2008;40(5):575-583.
31. Johansson A, Marroni F, Hayward C, et al. Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis. Hum Mol Genet. 2009; 18(2):373-380.
32. Lei SF, Tan LJ, Liu XG, et al. Genome-wide association study identifies two novel loci containing FLNB and SBF2 genes underlying stature variation. Hum Mol Genet. 2009;18(9): 1661-1669.
33. Soranzo N, Rivadeneira F, Chinappen-Horsley U, et al. Meta-analysis of genome-wide scans for human adult stature identifies novel loci and associations with measures of skeletal frame size. PLoS Genet. 2009;5(4):e1000445.
34. Lango Allen H, Estrada K, Lettre G, et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 2010;467(7317):832-838.
35. Fried LP, Borhani NO, Enright P, et al. The Cardiovascular Health Study: design and rationale. Ann Epidemiol. 1991;1(3): 263-276.
36. Psaty BM, Kuller LH, Bild D, et al. Methods of assessing prevalent cardiovascular disease in the Cardiovascular Health Study. Ann Epidemiol. 1995;5(4):270-277.
37. Cushman M, Cornell ES, Howard PR, et al. Laboratory methods and quality assurance in the Cardiovascular Health Study. Clin Chem. 1995;41(2):264-270.
38. Mozaffarian D, Psaty BM, Rimm EB, et al. Fish intake and risk of incident atrial fibrillation. Circulation. 2004;110(4): 368-373.
39. Suchy-Dicey AM, Enquobahrie DA, Heckbert SR, et al. Hemodynamic fluid shear stress response genes and carotid intima-media thickness: a candidate gene association analysis in the Cardiovascular Health Study. Int J Mol Epidemiol Genet. 2012;3(2):174-178.
40. Estrada K, Krawczak M, Schreiber S, et al. A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation. Hum Mol Genet. 2009;18(18): 3516-3524.
41. Lanktree MB, Guo Y, Murtaza M, et al. Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height. Am J Hum Genet. 2011;88(1):6-18.
42. Arnold AM, Kronmal RA. Multiple imputation of baseline data in the Cardiovascular Health Study. Am J Epidemiol. 2003; 157(1):74-84.
43. Psaty BM, O'Donnell CJ, Gudnason V, et al. Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: design of prospective meta-analyses of genome-wide association studies from 5 cohorts. Circ Cardiovasc Genet. 2009;2(1):73-80.
44. Johnson AD, Handsaker RE, Pulit SL, et al. SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics. 2008;24(24): 2938-2939.
45. National Center for Biotechnology Information, National Library of Medicine. Reference SNP (refSNP) Cluster Report: rs1046934. Bethesda, MD: National Library of Medicine; 2013. (http://www.ncbi.nlm.nih.gov/projects/SNP/ snp-ref.cgi? rs=1046934). (Accessed March 13, 2013).
46. Corradi D. Atrial fibrillation from the pathologist's perspective. Cardiovasc Pathol. 2014;23(2):71-84.
47. Cassandrini D, Biancheri R, Tessa A, et al. Pontocerebellar hypoplasia: clinical, pathologic, and genetic studies. Neurology. 2010;75(16):1459-1464.
48. Yang J, Benyamin B, McEvoy BP, et al. Common SNPs explain a large proportion of the heritability for human height. Nat Genet. 2010;42(7):565-569.