The Toxin-Antitoxin System DarTG Catalyzes Reversible ADP-Ribosylation of DNA

Molecular Cell

Volumn 64, Issue 6, 2016, Pages 1109-1116

  Jankevicius, Gytis ^a   Ariza, Antonio ^a   Ahel, Marijan ^b   Ahel, Ivan ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b RUDER BO KOVI INSTITUTE   (Croatia)

Author keywords

ADP ribosylation; antitoxin; DarTG; DNA damage; DUF; macrodomain; NAD; PARP; persistence; toxin

Indexed keywords

ANTITOXIN; DNA; SINGLE STRANDED DNA; THYMIDINE; TOXIN; ADENOSINE DIPHOSPHATE; BACTERIAL TOXIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BINDING; RECOMBINANT PROTEIN;

ADENOSINE DIPHOSPHATE RIBOSYLATION; APOPTOSIS; ARTICLE; BACTERIAL GROWTH; BACTERIOPHAGE; BACTERIUM CULTURE; BIOFILM; DNA REPAIR; ESCHERICHIA COLI; GROWTH REGULATION; IN VITRO STUDY; LIGAND BINDING; MOLECULAR CLONING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROKARYOTE; PROTEIN DOMAIN; ANTAGONISTS AND INHIBITORS; BINDING SITE; CHEMISTRY; ENZYME SPECIFICITY; GENE EXPRESSION; GENETICS; METABOLISM; MOLECULAR MODEL; PATHOGENICITY; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ADENOSINE DIPHOSPHATE; ADP RIBOSE TRANSFERASES; AMINO ACID MOTIFS; ANTITOXINS; BACTERIAL TOXINS; BINDING SITES; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; DNA, SINGLE-STRANDED; ESCHERICHIA COLI; GENE EXPRESSION; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; THYMIDINE;

EID: 85008226645     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.11.014     Document Type: Article

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