Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease

EMBO Journal

Volumn 32, Issue 9, 2013, Pages 1225-1237

  Sharifi, Reza ^a   Morra, Rosa ^b   Denise Appel, C ^c   Tallis, Michael ^b   Chioza, Barry ^a   Jankevicius, Gytis ^d   Simpson, Michael A ^e   Matic, Ivan ^f   Ozkan, Ege ^a   Golia, Barbara ^d   Schellenberg, Matthew J ^c   Weston, Ria ^b   Williams, Jason G ^c   Rossi, Marianna N ^b   Galehdari, Hamid ^g   Krahn, Juno ^c   Wan, Alexander ^a   Trembath, Richard C ^e   Crosby, Andrew H ^a   Ahel, Dragana ^b   Hay, Ron ^f   Ladurner, Andreas G ^d,h,i   Timinszky, Gyula ^d   Scott Williams, R ^c   Ahel, Ivan ^b   more..

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^d UNIVERSITY OF MUNICH   (Germany)

^e KING'S COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF DUNDEE   (United Kingdom)

^g SHAHID CHAMRAN UNIVERSITY OF AHVAZ   (Iran)

^h Munich Center for Integrated Protein Science   (Germany)

ⁱ Munich Cluster for Systems Neurology ^*  (Germany)

Author keywords

ADP ribose; DNA damage; macrodomain; neurodegeneration; PARP

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; C6ORF130 PROTEIN; GLUTAMIC ACID; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ARTICLE; CATALYSIS; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; GENE MUTATION; HOMOZYGOSITY; HUMAN; NERVE DEGENERATION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN STRUCTURE; X RAY ANALYSIS;

AMINO ACID SEQUENCE; BASE SEQUENCE; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; FAMILY; FEMALE; GLYCOSIDE HYDROLASES; HEK293 CELLS; HELA CELLS; HUMANS; MALE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEURODEGENERATIVE DISEASES; PEDIGREE; POLY ADENOSINE DIPHOSPHATE RIBOSE; PROTEIN PROCESSING, POST-TRANSLATIONAL; SEQUENCE HOMOLOGY, AMINO ACID; THIOLESTER HYDROLASES;

MAMMALIA;

EID: 84877634923     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2013.51     Document Type: Article

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