메뉴 건너뛰기




Volumn 28, Issue 1, 2017, Pages 41-53

Reconstituting regulation of the canonical Wnt pathway by engineering a minimal β-catenin destruction machine

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; APC1 PROTEIN; APC2 PROTEIN; AXIN; BETA CATENIN; CHIMERIC PROTEIN; PROTEIN KINASE C GAMMA; UNCLASSIFIED DRUG; WNT PROTEIN; REPRESSOR PROTEIN;

EID: 85008187240     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E16-07-0557     Document Type: Article
Times cited : (20)

References (39)
  • 1
    • 0036339813 scopus 로고    scopus 로고
    • Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development
    • Ahmed Y, Nouri A, Wieschaus E (2002). Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development. Development 129, 1751-1762.
    • (2002) Development , vol.129 , pp. 1751-1762
    • Ahmed, Y.1    Nouri, A.2    Wieschaus, E.3
  • 2
    • 0036389796 scopus 로고    scopus 로고
    • Drosophila APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs
    • Akong K, Grevengoed E, Price M, McCartney B, Hayden M, DeNofrio J, Peifer M (2002). Drosophila APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs. Dev Biol 250, 91-100.
    • (2002) Dev Biol , vol.250 , pp. 91-100
    • Akong, K.1    Grevengoed, E.2    Price, M.3    McCartney, B.4    Hayden, M.5    DeNofrio, J.6    Peifer, M.7
  • 4
    • 77149174855 scopus 로고    scopus 로고
    • Wnt signaling from development to disease: Insights from model systems
    • Cadigan KM, Peifer M (2009). Wnt signaling from development to disease: insights from model systems. Cold Spring Harb Perspect Biol 1, a002881.
    • (2009) Cold Spring Harb Perspect Biol , vol.1 , pp. a002881
    • Cadigan, K.M.1    Peifer, M.2
  • 5
    • 84887599280 scopus 로고    scopus 로고
    • Α-Catenin interacts with APC to regulate β-catenin proteolysis and transcriptional repression of Wnt target genes
    • Choi SH, Estarás C, Moresco JJ, Yates JR, Jones KA (2013). α-Catenin interacts with APC to regulate β-catenin proteolysis and transcriptional repression of Wnt target genes. Genes Dev 27, 2473-2488.
    • (2013) Genes Dev , vol.27 , pp. 2473-2488
    • Choi, S.H.1    Estarás, C.2    Moresco, J.J.3    Yates, J.R.4    Jones, K.A.5
  • 6
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling and disease
    • Clevers H, Nusse R (2012). Wnt/beta-catenin signaling and disease. Cell 149, 1192-1205.
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 7
    • 1542297761 scopus 로고    scopus 로고
    • Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin
    • Cong F, Varmus H (2004). Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin. Proc Natl Acad Sci USA 101, 2882-2887.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 2882-2887
    • Cong, F.1    Varmus, H.2
  • 9
    • 0033011602 scopus 로고    scopus 로고
    • DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability
    • Kishida S, Yamamoto H, Hino SI, Ikeda S, Kishida M, Kikuchi A (1999). DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability. Mol Cell Biol 19, 4414-4422.
    • (1999) Mol Cell Biol , vol.19 , pp. 4414-4422
    • Kishida, S.1    Yamamoto, H.2    Hino, S.I.3    Ikeda, S.4    Kishida, M.5    Kikuchi, A.6
  • 10
    • 58049196841 scopus 로고    scopus 로고
    • Beta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours
    • Kohler EM, Chandra SH, Behrens J, Schneikert J (2009). Beta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours. Hum Mol Genet 18, 213-226.
    • (2009) Hum Mol Genet , vol.18 , pp. 213-226
    • Kohler, E.M.1    Chandra, S.H.2    Behrens, J.3    Schneikert, J.4
  • 11
    • 84908635494 scopus 로고    scopus 로고
    • Self-association of the APC tumor suppressor is required for the assembly, stability, and activity of the Wnt signaling destruction complex
    • Kunttas-Tatli E, Roberts DM, McCartney BM (2014). Self-association of the APC tumor suppressor is required for the assembly, stability, and activity of the Wnt signaling destruction complex. Mol Biol Cell 25, 3424-3436.
    • (2014) Mol Biol Cell , vol.25 , pp. 3424-3436
    • Kunttas-Tatli, E.1    Roberts, D.M.2    McCartney, B.M.3
  • 12
    • 84858266348 scopus 로고    scopus 로고
    • Destruction complex function in the Wnt signaling pathway of Drosophila requires multiple interactions between Adenomatous polyposis coli 2 and Armadillo
    • Kunttas-Tatli E, Zhou MN, Zimmerman S, Molinar O, Zhouzheng F, Carter K, Kapur M, Cheatle A, Decal R, McCartney BM (2012). Destruction complex function in the Wnt signaling pathway of Drosophila requires multiple interactions between Adenomatous polyposis coli 2 and Armadillo. Genetics 190, 1059-1075.
    • (2012) Genetics , vol.190 , pp. 1059-1075
    • Kunttas-Tatli, E.1    Zhou, M.N.2    Zimmerman, S.3    Molinar, O.4    Zhouzheng, F.5    Carter, K.6    Kapur, M.7    Cheatle, A.8    Decal, R.9    McCartney, B.M.10
  • 13
    • 4243067196 scopus 로고    scopus 로고
    • The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway
    • Lee E, Salic A, Kruger R, Heinrich R, Kirschner MW (2003). The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. PLoS Biol 1, E10.
    • (2003) PLoS Biol , vol.1 , pp. E10
    • Lee, E.1    Salic, A.2    Kruger, R.3    Heinrich, R.4    Kirschner, M.W.5
  • 16
    • 33745276261 scopus 로고    scopus 로고
    • The third 20 amino acid repeat is the tightest binding site of APC for beta-catenin
    • Liu J, Xing Y, Hinds TR, Zheng J, Xu W (2006). The third 20 amino acid repeat is the tightest binding site of APC for beta-catenin. J Mol Biol 360, 133-144.
    • (2006) J Mol Biol , vol.360 , pp. 133-144
    • Liu, J.1    Xing, Y.2    Hinds, T.R.3    Zheng, J.4    Xu, W.5
  • 17
    • 84867071759 scopus 로고    scopus 로고
    • A finger on the pulse of Wnt receptor signaling
    • MacDonald BT, He X (2012). A finger on the pulse of Wnt receptor signaling. Cell Res 22, 1410-1412.
    • (2012) Cell Res , vol.22 , pp. 1410-1412
    • MacDonald, B.T.1    He, X.2
  • 19
    • 84861699364 scopus 로고    scopus 로고
    • The APC tumour suppressor is essential for Axin complex assembly and function, and opposes Axin's interaction with Dishevelled
    • Mendoza-Topaz C, Mieszczanek J, Bienz M (2011). The APC tumour suppressor is essential for Axin complex assembly and function, and opposes Axin's interaction with Dishevelled. Open Biol 1, 110013.
    • (2011) Open Biol , vol.1 , pp. 110013
    • Mendoza-Topaz, C.1    Mieszczanek, J.2    Bienz, M.3
  • 20
    • 0031813650 scopus 로고    scopus 로고
    • Axin, an inhibitor of the Wnt signalling pathway, interacts with beta- catenin, GSK-3beta and APC and reduces the beta-catenin level
    • Nakamura T, Hamada F, Ishidate T, Anai K, Kawahara K, Toyoshima K, Akiyama T (1998). Axin, an inhibitor of the Wnt signalling pathway, interacts with beta- catenin, GSK-3beta and APC and reduces the beta-catenin level. Genes Cells 3, 395-403.
    • (1998) Genes Cells , vol.3 , pp. 395-403
    • Nakamura, T.1    Hamada, F.2    Ishidate, T.3    Anai, K.4    Kawahara, K.5    Toyoshima, K.6    Akiyama, T.7
  • 21
    • 33845234807 scopus 로고    scopus 로고
    • Cytoskeleton out of the cupboard: Colon cancer and cytoskeletal changes induced by loss of APC
    • Näthke I (2006). Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC. Nat Rev Cancer 6, 967-974.
    • (2006) Nat Rev Cancer , vol.6 , pp. 967-974
    • Näthke, I.1
  • 22
    • 0034710914 scopus 로고    scopus 로고
    • Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm
    • Neufeld KL, Nix DA, Bogerd H, Kang Y, Beckerle MC, Cullen BR, White RL (2000). Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm. Proc Natl Acad Sci USA 97, 12085-12090.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12085-12090
    • Neufeld, K.L.1    Nix, D.A.2    Bogerd, H.3    Kang, Y.4    Beckerle, M.C.5    Cullen, B.R.6    White, R.L.7
  • 23
    • 48949115368 scopus 로고    scopus 로고
    • Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo
    • Peterson-Nedry W, Erdeniz N, Kremer S, Yu J, Baig-Lewis S, Wehrli M (2008). Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo. Dev Biol 320, 226-241.
    • (2008) Dev Biol , vol.320 , pp. 226-241
    • Peterson-Nedry, W.1    Erdeniz, N.2    Kremer, S.3    Yu, J.4    Baig-Lewis, S.5    Wehrli, M.6
  • 24
    • 84982112046 scopus 로고    scopus 로고
    • The Miraprep: A protocol that uses a Miniprep kit and provides Maxiprep yields
    • Pronobis MI, Deuitch N, Peifer M (2016). The Miraprep: a protocol that uses a Miniprep kit and provides Maxiprep yields. PLoS One 11, e0160509.
    • (2016) PLoS One , vol.11 , pp. e0160509
    • Pronobis, M.I.1    Deuitch, N.2    Peifer, M.3
  • 25
    • 84943781425 scopus 로고    scopus 로고
    • A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient betacatenin destruction
    • Pronobis MI, Rusan NM, Peifer M (2015). A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient betacatenin destruction. Elife 4, e08022.
    • (2015) Elife , vol.4 , pp. e08022
    • Pronobis, M.I.1    Rusan, N.M.2    Peifer, M.3
  • 26
    • 84861698254 scopus 로고    scopus 로고
    • Regulation of Wnt signaling by the tumor suppressor APC does not require ability to enter the nucleus nor a particular cytoplasmic localization
    • Roberts DM, Pronobis MI, Poulton JS, Kane EG, Peifer M (2012). Regulation of Wnt signaling by the tumor suppressor APC does not require ability to enter the nucleus nor a particular cytoplasmic localization. Mol Biol Cell 23, 2041-2056.
    • (2012) Mol Biol Cell , vol.23 , pp. 2041-2056
    • Roberts, D.M.1    Pronobis, M.I.2    Poulton, J.S.3    Kane, E.G.4    Peifer, M.5
  • 27
    • 79957597124 scopus 로고    scopus 로고
    • Deconstructing the beta-catenin destruction complex: Mechanistic roles for the tumor suppressor APC in regulating Wnt signaling
    • Roberts DM, Pronobis MI, Poulton JS, Waldmann JD, Stephenson EM, Hanna S, Peifer M (2011). Deconstructing the beta-catenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling. Mol Biol Cell 22, 1845-1863.
    • (2011) Mol Biol Cell , vol.22 , pp. 1845-1863
    • Roberts, D.M.1    Pronobis, M.I.2    Poulton, J.S.3    Waldmann, J.D.4    Stephenson, E.M.5    Hanna, S.6    Peifer, M.7
  • 28
    • 0030871048 scopus 로고    scopus 로고
    • Loss of ß-catenin regulation by the apc tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene
    • Rubinfeld B, Albert I, Porfiri E, Munemitsu S, Polakis P (1997). Loss of ß-catenin regulation by the apc tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene. Cancer Res 57, 4624-4630.
    • (1997) Cancer Res , vol.57 , pp. 4624-4630
    • Rubinfeld, B.1    Albert, I.2    Porfiri, E.3    Munemitsu, S.4    Polakis, P.5
  • 30
    • 15044348490 scopus 로고    scopus 로고
    • The links between axin and carcinogenesis
    • Salahshor S, Woodgett JR (2005). The links between axin and carcinogenesis. J Clin Pathol 58, 225-236.
    • (2005) J Clin Pathol , vol.58 , pp. 225-236
    • Salahshor, S.1    Woodgett, J.R.2
  • 31
    • 0033714885 scopus 로고    scopus 로고
    • Control of beta-catenin stability: Reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts
    • Salic A, Lee E, Mayer L, Kirschner MW (2000). Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts. Mol Cell 5, 523-532.
    • (2000) Mol Cell , vol.5 , pp. 523-532
    • Salic, A.1    Lee, E.2    Mayer, L.3    Kirschner, M.W.4
  • 34
    • 0034657187 scopus 로고    scopus 로고
    • Structural basis of the Axin-adenomatous polyposis coli interaction
    • Spink KE, Polakis P, Weis WI (2000). Structural basis of the Axin-adenomatous polyposis coli interaction. EMBO J 19, 2270-2279.
    • (2000) EMBO J , vol.19 , pp. 2270-2279
    • Spink, K.E.1    Polakis, P.2    Weis, W.I.3
  • 37
    • 84906877425 scopus 로고    scopus 로고
    • Assemblages: Functional units formed by cellular phase separation
    • Toretsky JA, Wright PE (2014). Assemblages: functional units formed by cellular phase separation. J Cell Biol 206, 579-588.
    • (2014) J Cell Biol , vol.206 , pp. 579-588
    • Toretsky, J.A.1    Wright, P.E.2
  • 38
    • 0032841989 scopus 로고    scopus 로고
    • A Drosophila Axin homolog, Daxin, inhibits Wnt signaling
    • Willert K, Logan CY, Arora A, Fish M, Nusse R (1999). A Drosophila Axin homolog, Daxin, inhibits Wnt signaling. Development 126, 4165-4173.
    • (1999) Development , vol.126 , pp. 4165-4173
    • Willert, K.1    Logan, C.Y.2    Arora, A.3    Fish, M.4    Nusse, R.5
  • 39
    • 84905666093 scopus 로고    scopus 로고
    • Testing models of the APC tumor suppressor/beta-catenin interaction reshapes our view of the destruction complex in Wnt signaling
    • Yamulla RJ, Kane EG, Moody AE, Politi KA, Lock NE, Foley AV, Roberts DM (2014). Testing models of the APC tumor suppressor/beta-catenin interaction reshapes our view of the destruction complex in Wnt signaling. Genetics 197, 1285-1302.
    • (2014) Genetics , vol.197 , pp. 1285-1302
    • Yamulla, R.J.1    Kane, E.G.2    Moody, A.E.3    Politi, K.A.4    Lock, N.E.5    Foley, A.V.6    Roberts, D.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.