Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations

Journal of Allergy and Clinical Immunology

Volumn 140, Issue 1, 2017, Pages 223-231

  Hoshino, Akihiro ^a,b   Okada, Satoshi ^c   Yoshida, Kenichi ^d   Nishida, Naonori ^a   Okuno, Yusuke ^e   Ueno, Hiroo ^d   Yamashita, Motoi ^b   Okano, Tsubasa ^b   Tsumura, Miyuki ^c   Nishimura, Shiho ^c   Sakata, Sonoko ^c   Kobayashi, Masao ^c   Nakamura, Haruna ^f   Kamizono, Junji ^g   Mitsui Sekinaka, Kanako ^h   Ichimura, Takuya ⁱ   Ohga, Shouichi ⁱ   Nakazawa, Yozo ^j   Takagi, Masatoshi ^b   Imai, Kohsuke ^b   Shiraishi, Yuichi ^k   Chiba, Kenichi ^k   Tanaka, Hiroko ^k   Miyano, Satoru ^k   Ogawa, Seishi ^d   Kojima, Seiji ^e   Nonoyama, Shigeaki ^h   Morio, Tomohiro ^b   Kanegane, Hirokazu ^b   more..

^a UNIVERSITY OF TOYAMA   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f MIE NATIONAL HOSPITAL   (Japan)

^g KITAKYUSHU CITY YAHATA HOSPITAL   (Japan)

^h NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

ⁱ YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^j SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^k UNIVERSITY OF TOKYO   (Japan)

more..

Author keywords

Acute lymphoblastic leukemia; autoimmune disease; B cell deficiency; common lymphoid progenitor; DNA binding; dysgammaglobulinemia; germline mutation; Ikaros; IKZF1; nuclear localization

Indexed keywords

IKAROS TRANSCRIPTION FACTOR; MUTANT PROTEIN; IKZF1 PROTEIN, HUMAN;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOIMMUNITY; B CELL DEFICIENCY; BONE MARROW; CHILD; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DYSGAMMAGLOBULINEMIA; FEMALE; FLOW CYTOMETRY; GENE; GERMLINE MUTATION; HEMATOPOIESIS; HETEROZYGOSITY; HUMAN; HUMAN CELL; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IGA VASCULITIS; IKZF1 GENE; IMMUNE DEFICIENCY; INFANT; JAPANESE (PEOPLE); LYMPHOID PROGENITOR CELL; LYMPHOPOIESIS; MALE; NUCLEAR LOCALIZATION SIGNAL; ONSET AGE; PANCYTOPENIA; PHENOTYPE; PRE B LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN DNA BINDING; SCHOOL CHILD; SYSTEMIC LUPUS ERYTHEMATOSUS; WHOLE EXOME SEQUENCING; YOUNG ADULT; AUTOIMMUNE DISEASE; B LYMPHOCYTE; GENETICS; HEMATOLOGIC DISEASE; IMMUNOLOGY; LYMPHOCYTE COUNT; T LYMPHOCYTE;

ADOLESCENT; ADULT; AUTOIMMUNE DISEASES; AUTOIMMUNITY; B-LYMPHOCYTES; CHILD; FEMALE; GERM-LINE MUTATION; HEMATOLOGIC DISEASES; HEMATOPOIESIS; HUMANS; IKAROS TRANSCRIPTION FACTOR; LYMPHOCYTE COUNT; MALE; T-LYMPHOCYTES; YOUNG ADULT;

EID: 85007560223     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2016.09.029     Document Type: Article

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