Model-based optimization and scale-up of multi-feed simultaneous saccharification and co-fermentation of steam pre-treated lignocellulose enables high gravity ethanol production

Biotechnology for Biofuels

Volumn 9, Issue 1, 2016, Pages

  Wang, Ruifei ^a   Unrean, Pornkamol ^a,b   Franzén, Carl Johan ^a  

^a CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^b NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

Author keywords

Agricultural residues; Biofuels; Bioprocessing; Demo scale simultaneous saccharification and fermentation; Enzymatic hydrolysis; Fed batch SSF; Fermentation technology; High gravity; Mathematical modelling

Indexed keywords

AGRICULTURAL WASTES; BATCH DATA PROCESSING; BIOFUELS; BIOLOGICAL WATER TREATMENT; CELLULOSE; ENZYMATIC HYDROLYSIS; ENZYMES; ETHANOL; FEEDING; FERMENTATION; HYDROLYSIS; LIGNIN; MASS TRANSFER; MATHEMATICAL MODELS; STRAW; SULFUR DIOXIDE; YEAST;

BIOPROCESSING; FED BATCHES; FERMENTATION TECHNOLOGIES; HIGH GRAVITY; SIMULTANEOUS SACCHARIFICATION AND FERMENTATION;

SACCHARIFICATION;

BIOFUEL; CELLULOSE; ENZYME ACTIVITY; ETHANOL; FERMENTATION; HYDROLYSIS; LIGNIN; OPTIMIZATION; PLANT RESIDUE; PROCESSING;

ENZYMOLYSIS; FERMENTATION; FUELS; MATHEMATICAL MODELS; PLANT RESIDUES; SACCHARIFICATION;

TRITICUM AESTIVUM;

EID: 85007560207     PISSN: 17546834     EISSN: None     Source Type: Journal    
DOI: 10.1186/s13068-016-0500-7     Document Type: Article

References (29)

1. Wingren A, Galbe M, Zacchi G. Techno-economic evaluation of producing ethanol from softwood: comparison of SSF and SHF and identification of bottlenecks. Biotechnol Progr. 2003;19:1109-17.
2. Olofsson K, Wiman M, Lidén G. Controlled feeding of cellulases improves conversion of xylose in simultaneous saccharification and co-fermentation for bioethanol production. J Biotechnol. 2010;145:168-75.
3. Sassner P, Galbe M, Zacchi G. Techno-economic evaluation of bioethanol production from three different lignocellulosic materials. Biomass Bioenergy. 2008;32:422-30.
4. Sassner P, Galbe M, Zacchi G. Bioethanol production based on simultaneous saccharification and fermentation of steam-pretreated Salix at high dry-matter content. Enzyme Microb Technol. 2006;39:756-62.
5. Georgieva TI, Hou XR, Hilstrom T, Ahring BK. Enzymatic hydrolysis and ethanol fermentation of high dry matter wet-exploded wheat straw at low enzyme loading. Appl Biochem Biotechnol. 2008;148:35-44.
6. Bertilsson M, Olofsson K, Liden G. Prefermentation improves xylose utilization in simultaneous saccharification and co-fermentation of pretreated spruce. Biotechnol Biofuels. 2009;2:8.
7. Hoyer K, Galbe M, Zacchi G. Production of fuel ethanol from softwood by simultaneous saccharification and fermentation at high dry matter content. J Chem Technol Biotechnol. 2009;84:570-7.
8. Janssen M, Tillman A-M, Cannella D, Jørgensen H. Influence of high gravity process conditions on the environmental impact of ethanol production from wheat straw. Bioresour Technol. 2014;173:148-58.
9. Wang R, Koppram R, Olsson L, Franzén CJ. Kinetic modeling of multi-feed simultaneous saccharification and co-fermentation of pretreated birch to ethanol. Bioresour Technol. 2014;172:303-11.
10. Koppram R, Olsson L. Combined substrate, enzyme and yeast feed in simultaneous saccharification and fermentation allow bioethanol production from pretreated spruce biomass at high solids loadings. Biotechnol Biofuels. 2014;7:54.
11. Koppram R, Nielsen F, Albers E, Lambert A, Wannstrom S, Welin L, Zacchi G, Olsson L. Simultaneous saccharification and co-fermentation for bioethanol production using corncobs at lab PDU and demo scales. Biotechnol Biofuels. 2013;6:2.
12. Hoyer K, Galbe M, Zacchi G. Effects of enzyme feeding strategy on ethanol yield in fed-batch simultaneous saccharification and fermentation of spruce at high dry matter. Biotechnol Biofuels. 2010;3:14.
13. Hodge DB, Karim MN, Schell DJ, McMillan JD. Model-based fed-batch for high-solids enzymatic cellulose hydrolysis. Appl Biochem Biotechnol. 2009;152:88-107.
14. Liu ZL. Molecular mechanisms of yeast tolerance and in situ detoxification of lignocellulose hydrolysates. Appl Microbiol Biotechnol. 2011;90:809-25.
15. Tomás-Pejó E, Olsson L. Influence of the propagation strategy for obtaining robust Saccharomyces cerevisiae cells that efficiently co-ferment xylose and glucose in lignocellulosic hydrolysates. Microb Biotechnol. 2015;8:999-1005.
16. Alkasrawi M, Rudolf A, Lidén G, Zacchi G. Influence of strain and cultivation procedure on the performance of simultaneous saccharification and fermentation of steam pretreated spruce. Enzyme Microb Technol. 2006;38:279-86.
17. Almeida JRM, Modig T, Petersson A, Hahn-Hägerdal B, Lidén G, Gorwa-Grauslund MF. Increased tolerance and conversion of inhibitors in lignocellulosic hydrolysates by Saccharomyces cerevisiae. J Chem Technol Biotechnol. 2007;82:340-9.
18. Van Hoek P, Van Dijken JP, Pronk JT. Effect of specific growth rate on fermentative capacity of baker's yeast. Appl Environ Microbiol. 1998;64:4226-33.
19. Yarbrough JM, Mittal A, Mansfield E, Taylor LE, Hobdey SE, Sammond DW, Bomble YJ, Crowley MF, Decker SR, Himmel ME, Vinzant TB. New perspective on glycoside hydrolase binding to lignin from pretreated corn stover. Biotechnol Biofuels. 2015;8:214.
20. Unrean P, Khajeeram S, Laoteng K. Systematic optimization of fed-batch simultaneous saccharification and fermentation at high-solid loading based on enzymatic hydrolysis and dynamic metabolic modeling of Saccharomyces cerevisiae. Appl Microbiol Biotechnol. 2015;100:2459-70.
21. Xiros C, Olsson L. Comparison of strategies to overcome the inhibitory effects in high-gravity fermentation of lignocellulosic hydrolysates. Biomass Bioenergy. 2014;65:79-90.
22. Beckner M, Ivey ML, Phister TG. Microbial contamination of fuel ethanol fermentations. Lett Appl Microbiol. 2011;53:387-94.
23. Westman JO, Mapelli V, Taherzadeh MJ, Franzen CJ. Flocculation causes inhibitor tolerance in Saccharomyces cerevisiae for second-generation bioethanol production. Appl Environ Microbiol. 2014;80:6908-18.
24. Sluiter A, Hames B, Ruiz R, Scarlata C, Sluiter J, Templeton D, Crocker D. Determination of structural carbohydrates and lignin in biomass: Laboratory Analytical Procedure (LAP) (Revised August 2012). Issue Date: 4/25/2008. NREL/TP-510-42618. http://www.nrel.gov/docs/gen/fy13/42618.pdf.
25. Adney B, Baker J. Measurement of cellulase activities: Laboratory Analytical Procedure (LAP). Issue Date 08/12/1996, NREL/TP-510-42628. http://www.nrel.gov/docs/gen/fy08/42628.pdf.
26. Xiao Z, Storms R, Tsang A. Microplate-based filter paper assay to measure total cellulase activity. Biotechnol Bioeng. 2004;88:832-7.
27. Tomás-Pejó E, Bonander N, Olsson L. Industrial yeasts strains for biorefinery solutions: constructing and selecting efficient barcoded xylose fermenting strains for ethanol. Biofuels Bioprod Bioref. 2014;8:626-34.
28. Verduyn C, Postma E, Scheffers WA, Van Dijken JP. Effect of benzoic acid on metabolic fluxes in yeasts: a continuous-culture study on the regulation of respiration and alcoholic fermentation. Yeast. 1992;8:501-17.
29. Zhang JY, Shao XJ, Townsend OV, Lynd LR. Simultaneous saccharification and co-fermentation of paper sludge to ethanol by Saccharomyces cerevisiae RWB222-Part I: kinetic modeling and parameters. Biotechnol Bioeng. 2009;104:920-31.