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Volumn 10, Issue 12, 2016, Pages 10636-10651

Gold Nanoparticle Reprograms Pancreatic Tumor Microenvironment and Inhibits Tumor Growth

Author keywords

gold nanoparticles; pancreatic cancer; stellate cells; tumor microenvironment

Indexed keywords

CELLS; CROSSTALK; CYTOLOGY; DISEASES; ENZYME ACTIVITY; FIBER OPTIC SENSORS; GOLD; METAL NANOPARTICLES; NANOPARTICLES; PROTEINS; TUMORS;

EID: 85007559438     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.6b02231     Document Type: Article
Times cited : (137)

References (78)
  • 3
    • 34248141223 scopus 로고    scopus 로고
    • Tumor-Stroma Interactions in Pancreatic Ductal Adenocarcinoma
    • Mahadevan, D.; Von Hoff, D. D. Tumor-Stroma Interactions in Pancreatic Ductal Adenocarcinoma Mol. Cancer Ther. 2007, 6, 1186-1197 10.1158/1535-7163.MCT-06-0686
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 1186-1197
    • Mahadevan, D.1    Von Hoff, D.D.2
  • 4
    • 84863082623 scopus 로고    scopus 로고
    • Dangerous Liaisons: Pancreatic Stellate Cells and Pancreatic Cancer Cells
    • Apte, M. V.; Wilson, J. S. Dangerous Liaisons: Pancreatic Stellate Cells and Pancreatic Cancer Cells J. Gastroenterol. Hepatol. 2012, 27, 69-74 10.1111/j.1440-1746.2011.07000.x
    • (2012) J. Gastroenterol. Hepatol. , vol.27 , pp. 69-74
    • Apte, M.V.1    Wilson, J.S.2
  • 5
    • 33845998896 scopus 로고    scopus 로고
    • The Pancreatic Stellate Cell: A Star on the Rise in Pancreatic Diseases
    • Omary, M. B.; Lugea, A.; Lowe, A. W.; Pandol, S. J. The Pancreatic Stellate Cell: A Star on the Rise in Pancreatic Diseases J. Clin. Invest. 2007, 117, 50-59 10.1172/JCI30082
    • (2007) J. Clin. Invest. , vol.117 , pp. 50-59
    • Omary, M.B.1    Lugea, A.2    Lowe, A.W.3    Pandol, S.J.4
  • 7
    • 8144228952 scopus 로고    scopus 로고
    • Friends or Foes - Bipolar Effects of the Tumour Stroma in Cancer
    • Mueller, M. M.; Fusenig, N. E. Friends or Foes-Bipolar Effects of the Tumour Stroma in Cancer Nat. Rev. Cancer 2004, 4, 839-849 10.1038/nrc1477
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 839-849
    • Mueller, M.M.1    Fusenig, N.E.2
  • 9
    • 80054867856 scopus 로고    scopus 로고
    • Pancreatic Cancer: Fibroblast Co-conspirators
    • Seton-Rogers, S. Pancreatic Cancer: Fibroblast Co-conspirators Nat. Rev. Cancer 2011, 11, 758 10.1038/nrc3157
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 758
    • Seton-Rogers, S.1
  • 10
    • 84876786403 scopus 로고    scopus 로고
    • A Starring Role for Stellate Cells in the Pancreatic Cancer Microenvironment
    • Apte, M. V.; Wilson, J. S.; Lugea, A.; Pandol, S. J. A Starring Role for Stellate Cells in the Pancreatic Cancer Microenvironment Gastroenterology 2013, 144, 1210-1219 10.1053/j.gastro.2012.11.037
    • (2013) Gastroenterology , vol.144 , pp. 1210-1219
    • Apte, M.V.1    Wilson, J.S.2    Lugea, A.3    Pandol, S.J.4
  • 12
  • 13
    • 80655127773 scopus 로고    scopus 로고
    • Vitamin D Inhibits Proliferation and Profibrotic Marker Expression in Hepatic Stellate Cells and Decreases Thioacetamide-Induced Liver Fibrosis in Rats
    • Abramovitch, S.; Dahan-Bachar, L.; Sharvit, E.; Weisman, Y.; Ben Tov, A.; Brazowski, E.; Reif, S. Vitamin D Inhibits Proliferation and Profibrotic Marker Expression in Hepatic Stellate Cells and Decreases Thioacetamide-Induced Liver Fibrosis in Rats Gut 2011, 60, 1728-1737 10.1136/gut.2010.234666
    • (2011) Gut , vol.60 , pp. 1728-1737
    • Abramovitch, S.1    Dahan-Bachar, L.2    Sharvit, E.3    Weisman, Y.4    Ben Tov, A.5    Brazowski, E.6    Reif, S.7
  • 21
    • 34248583886 scopus 로고    scopus 로고
    • MAP Kinase Signalling Pathways in Cancer
    • Dhillon, A. S.; Hagan, S.; Rath, O.; Kolch, W. MAP Kinase Signalling Pathways in Cancer Oncogene 2007, 26, 3279-3290 10.1038/sj.onc.1210421
    • (2007) Oncogene , vol.26 , pp. 3279-3290
    • Dhillon, A.S.1    Hagan, S.2    Rath, O.3    Kolch, W.4
  • 23
    • 79955068416 scopus 로고    scopus 로고
    • Analysis of the Human Pancreatic Stellate Cell Secreted Proteome
    • Wehr, A. Y.; Furth, E. E.; Sangar, V.; Blair, I. A.; Yu, K. H. Analysis of the Human Pancreatic Stellate Cell Secreted Proteome Pancreas 2011, 40, 557-566 10.1097/MPA.0b013e318214efaf
    • (2011) Pancreas , vol.40 , pp. 557-566
    • Wehr, A.Y.1    Furth, E.E.2    Sangar, V.3    Blair, I.A.4    Yu, K.H.5
  • 25
    • 84928039023 scopus 로고    scopus 로고
    • Membrane-to-Nucleus Signals and Epigenetic Mechanisms for Myofibroblastic Activation and Desmoplastic Stroma: Potential Therapeutic Targets for Liver Metastasis?
    • Kang, N.; Shah, V. H.; Urrutia, R. Membrane-to-Nucleus Signals and Epigenetic Mechanisms for Myofibroblastic Activation and Desmoplastic Stroma: Potential Therapeutic Targets for Liver Metastasis? Mol. Cancer Res. 2015, 13, 604-612 10.1158/1541-7786.MCR-14-0542
    • (2015) Mol. Cancer Res. , vol.13 , pp. 604-612
    • Kang, N.1    Shah, V.H.2    Urrutia, R.3
  • 26
    • 84875199836 scopus 로고    scopus 로고
    • Mechanistic Insights into Self-Reinforcing Processes Driving Abnormal Histogenesis During the Development of Pancreatic Cancer
    • Iovanna, J. L.; Marks, D. L.; Fernandez-Zapico, M. E.; Urrutia, R. Mechanistic Insights into Self-Reinforcing Processes Driving Abnormal Histogenesis During the Development of Pancreatic Cancer Am. J. Pathol. 2013, 182, 1078-1086 10.1016/j.ajpath.2012.12.004
    • (2013) Am. J. Pathol. , vol.182 , pp. 1078-1086
    • Iovanna, J.L.1    Marks, D.L.2    Fernandez-Zapico, M.E.3    Urrutia, R.4
  • 29
    • 80053180372 scopus 로고    scopus 로고
    • Mechanism of Anti-Angiogenic Property of Gold Nanoparticles: Role of Nanoparticle Size and Surface Charge
    • Arvizo, R. R.; Rana, S.; Miranda, O. R.; Bhattacharya, R.; Rotello, V. M.; Mukherjee, P. Mechanism of Anti-Angiogenic Property of Gold Nanoparticles: Role of Nanoparticle Size and Surface Charge Nanomedicine 2011, 7, 580-587 10.1016/j.nano.2011.01.011
    • (2011) Nanomedicine , vol.7 , pp. 580-587
    • Arvizo, R.R.1    Rana, S.2    Miranda, O.R.3    Bhattacharya, R.4    Rotello, V.M.5    Mukherjee, P.6
  • 33
    • 84905472391 scopus 로고    scopus 로고
    • The IL-8/CXCR1 Axis Is Associated with Cancer Stem Cell-Like Properties and Correlates with Clinical Prognosis in Human Pancreatic Cancer Cases
    • Chen, L. Y.; Fan, J.; Chen, H.; Meng, Z. Q.; Chen, Z.; Wang, P.; Liu, L. M. The IL-8/CXCR1 Axis Is Associated with Cancer Stem Cell-Like Properties and Correlates with Clinical Prognosis in Human Pancreatic Cancer Cases Sci. Rep. 2014, 4, 5911 10.1038/srep05911
    • (2014) Sci. Rep. , vol.4 , pp. 5911
    • Chen, L.Y.1    Fan, J.2    Chen, H.3    Meng, Z.Q.4    Chen, Z.5    Wang, P.6    Liu, L.M.7
  • 34
    • 84862150896 scopus 로고    scopus 로고
    • Tumor-Derived Granulocyte-Macrophage Colony-Stimulating Factor Regulates Myeloid Inflammation and T Cell Immunity in Pancreatic Cancer
    • Bayne, L. J.; Beatty, G. L.; Jhala, N.; Clark, C. E.; Rhim, A. D.; Stanger, B. Z.; Vonderheide, R. H. Tumor-Derived Granulocyte-Macrophage Colony-Stimulating Factor Regulates Myeloid Inflammation and T Cell Immunity in Pancreatic Cancer Cancer Cell 2012, 21, 822-835 10.1016/j.ccr.2012.04.025
    • (2012) Cancer Cell , vol.21 , pp. 822-835
    • Bayne, L.J.1    Beatty, G.L.2    Jhala, N.3    Clark, C.E.4    Rhim, A.D.5    Stanger, B.Z.6    Vonderheide, R.H.7
  • 35
    • 84906938439 scopus 로고    scopus 로고
    • Oncogenic KRAS Signalling in Pancreatic Cancer
    • Eser, S.; Schnieke, A.; Schneider, G.; Saur, D. Oncogenic KRAS Signalling in Pancreatic Cancer Br. J. Cancer 2014, 111, 817-822 10.1038/bjc.2014.215
    • (2014) Br. J. Cancer , vol.111 , pp. 817-822
    • Eser, S.1    Schnieke, A.2    Schneider, G.3    Saur, D.4
  • 36
    • 4043074287 scopus 로고    scopus 로고
    • TGF-Beta1-Promoted Epithelial-to-Mesenchymal Transformation and Cell Adhesion Contribute to TGF-Beta1-Enhanced Cell Migration in SMMC-7721 Cells
    • Xu, Z.; Shen, M. X.; Ma, D. Z.; Wang, L. Y.; Zha, X. L. TGF-Beta1-Promoted Epithelial-to-Mesenchymal Transformation and Cell Adhesion Contribute to TGF-Beta1-Enhanced Cell Migration in SMMC-7721 Cells Cell Res. 2003, 13, 343-350 10.1038/sj.cr.7290179
    • (2003) Cell Res. , vol.13 , pp. 343-350
    • Xu, Z.1    Shen, M.X.2    Ma, D.Z.3    Wang, L.Y.4    Zha, X.L.5
  • 37
    • 44949144789 scopus 로고    scopus 로고
    • Activin A Increases Invasiveness of Endometrial Cells in an in vitro Model of Human Peritoneum
    • Ferreira, M. C.; Witz, C. A.; Hammes, L. S.; Kirma, N.; Petraglia, F.; Schenken, R. S.; Reis, F. M. Activin A Increases Invasiveness of Endometrial Cells in an in vitro Model of Human Peritoneum Mol. Hum. Reprod. 2008, 14, 301-307 10.1093/molehr/gan016
    • (2008) Mol. Hum. Reprod. , vol.14 , pp. 301-307
    • Ferreira, M.C.1    Witz, C.A.2    Hammes, L.S.3    Kirma, N.4    Petraglia, F.5    Schenken, R.S.6    Reis, F.M.7
  • 38
    • 75749088054 scopus 로고    scopus 로고
    • Epidermal Growth Factor and Hepatocyte Growth Factor Cooperate to Enhance Cell Proliferation, Scatter, and Invasion in Murine Mammary Epithelial Cells
    • Accornero, P.; Miretti, S.; Starvaggi Cucuzza, L.; Martignani, E.; Baratta, M. Epidermal Growth Factor and Hepatocyte Growth Factor Cooperate to Enhance Cell Proliferation, Scatter, and Invasion in Murine Mammary Epithelial Cells J. Mol. Endocrinol. 2010, 44, 115-125 10.1677/JME-09-0035
    • (2010) J. Mol. Endocrinol. , vol.44 , pp. 115-125
    • Accornero, P.1    Miretti, S.2    Starvaggi Cucuzza, L.3    Martignani, E.4    Baratta, M.5
  • 39
    • 84873248664 scopus 로고    scopus 로고
    • PDGF is Required for Remyelination-Promoting IgM Stimulation of Oligodendrocyte Progenitor Cell Proliferation
    • Watzlawik, J. O.; Warrington, A. E.; Rodriguez, M. PDGF is Required for Remyelination-Promoting IgM Stimulation of Oligodendrocyte Progenitor Cell Proliferation PLoS One 2013, 8, e55149 10.1371/journal.pone.0055149
    • (2013) PLoS One , vol.8 , pp. e55149
    • Watzlawik, J.O.1    Warrington, A.E.2    Rodriguez, M.3
  • 40
    • 84899937866 scopus 로고    scopus 로고
    • Getting RIDD of RNA: IRE1 in Cell Fate Regulation
    • Maurel, M.; Chevet, E.; Tavernier, J.; Gerlo, S. Getting RIDD of RNA: IRE1 in Cell Fate Regulation Trends Biochem. Sci. 2014, 39, 245-254 10.1016/j.tibs.2014.02.008
    • (2014) Trends Biochem. Sci. , vol.39 , pp. 245-254
    • Maurel, M.1    Chevet, E.2    Tavernier, J.3    Gerlo, S.4
  • 41
    • 68549092781 scopus 로고    scopus 로고
    • Regulated Ire1-Dependent decay of Messenger RNAs in Mammalian Cells
    • Hollien, J.; Lin, J. H.; Li, H.; Stevens, N.; Walter, P.; Weissman, J. S. Regulated Ire1-Dependent decay of Messenger RNAs in Mammalian Cells J. Cell Biol. 2009, 186, 323-331 10.1083/jcb.200903014
    • (2009) J. Cell Biol. , vol.186 , pp. 323-331
    • Hollien, J.1    Lin, J.H.2    Li, H.3    Stevens, N.4    Walter, P.5    Weissman, J.S.6
  • 42
    • 45749114525 scopus 로고    scopus 로고
    • The Role of Ire1Alpha in the Degradation of Insulin mRNA in Pancreatic Beta-Cells
    • Lipson, K. L.; Ghosh, R.; Urano, F. The Role of Ire1Alpha in the Degradation of Insulin mRNA in Pancreatic Beta-Cells PLoS One 2008, 3, e1648 10.1371/journal.pone.0001648
    • (2008) PLoS One , vol.3 , pp. e1648
    • Lipson, K.L.1    Ghosh, R.2    Urano, F.3
  • 43
    • 84874635907 scopus 로고    scopus 로고
    • Inhibiting the Growth of Pancreatic Adenocarcinoma in vitro and in vivo Through Targeted Treatment with Designer Gold Nanotherapeutics
    • Kudgus, R. A.; Szabolcs, A.; Khan, J. A.; Walden, C. A.; Reid, J. M.; Robertson, J. D.; Bhattacharya, R.; Mukherjee, P. Inhibiting the Growth of Pancreatic Adenocarcinoma in vitro and in vivo Through Targeted Treatment with Designer Gold Nanotherapeutics PLoS One 2013, 8, e57522 10.1371/journal.pone.0057522
    • (2013) PLoS One , vol.8 , pp. e57522
    • Kudgus, R.A.1    Szabolcs, A.2    Khan, J.A.3    Walden, C.A.4    Reid, J.M.5    Robertson, J.D.6    Bhattacharya, R.7    Mukherjee, P.8
  • 45
    • 79956075585 scopus 로고    scopus 로고
    • Pancreatic Stellate Cells Radioprotect Pancreatic Cancer Cells Through Beta1-Integrin Signaling
    • Mantoni, T. S.; Lunardi, S.; Al-Assar, O.; Masamune, A.; Brunner, T. B. Pancreatic Stellate Cells Radioprotect Pancreatic Cancer Cells Through Beta1-Integrin Signaling Cancer Res. 2011, 71, 3453-3458 10.1158/0008-5472.CAN-10-1633
    • (2011) Cancer Res. , vol.71 , pp. 3453-3458
    • Mantoni, T.S.1    Lunardi, S.2    Al-Assar, O.3    Masamune, A.4    Brunner, T.B.5
  • 49
    • 33746858503 scopus 로고    scopus 로고
    • Pancreatic Cancer: From Bench to 5-Year Survival
    • Kleeff, J.; C, M.; Friess, H.; Buchler, M. W. Pancreatic Cancer: From Bench to 5-Year Survival Pancreas 2006, 33, 111-118 10.1097/01.mpa.0000229010.62538.f2
    • (2006) Pancreas , vol.33 , pp. 111-118
    • Kleeff, J.C.M.1    Friess, H.2    Buchler, M.W.3
  • 50
    • 77955635233 scopus 로고    scopus 로고
    • Cancer Statistics, 2010
    • Jemal, A.; R, S.; Xu, J.; Ward, E. Cancer Statistics, 2010 Ca-Cancer J. Clin. 2010, 60, 277-300 10.3322/caac.20073
    • (2010) Ca-Cancer J. Clin. , vol.60 , pp. 277-300
    • Jemal, A.R.S.1    Xu, J.2    Ward, E.3
  • 51
    • 84858602107 scopus 로고    scopus 로고
    • Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
    • Provenzano, P. P.; Cuevas, C.; Chang, A. E.; Goel, V. K.; Von Hoff, D. D.; Hingorani, S. R. Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma Cancer Cell 2012, 21, 418-429 10.1016/j.ccr.2012.01.007
    • (2012) Cancer Cell , vol.21 , pp. 418-429
    • Provenzano, P.P.1    Cuevas, C.2    Chang, A.E.3    Goel, V.K.4    Von Hoff, D.D.5    Hingorani, S.R.6
  • 53
    • 2142646426 scopus 로고    scopus 로고
    • TGF-Beta Signaling and the Fibrotic Response
    • Leask, A.; Abraham, D. J. TGF-Beta Signaling and the Fibrotic Response FASEB J. 2004, 18, 816-827 10.1096/fj.03-1273rev
    • (2004) FASEB J. , vol.18 , pp. 816-827
    • Leask, A.1    Abraham, D.J.2
  • 54
    • 0031225015 scopus 로고    scopus 로고
    • Connective Tissue Growth Factor: A Mediator of TGF-Beta Action on Fibroblasts
    • Grotendorst, G. R. Connective Tissue Growth Factor: A Mediator of TGF-Beta Action on Fibroblasts Cytokine Growth Factor Rev. 1997, 8, 171-179 10.1016/S1359-6101(97)00010-5
    • (1997) Cytokine Growth Factor Rev. , vol.8 , pp. 171-179
    • Grotendorst, G.R.1
  • 55
    • 43049107543 scopus 로고    scopus 로고
    • Expression Pattern and Circulating Levels of Endostatin in Patients with Pancreas Cancer
    • Ohlund, D.; Ardnor, B.; Oman, M.; Naredi, P.; Sund, M. Expression Pattern and Circulating Levels of Endostatin in Patients with Pancreas Cancer Int. J. Cancer 2008, 122, 2805-2810 10.1002/ijc.23468
    • (2008) Int. J. Cancer , vol.122 , pp. 2805-2810
    • Ohlund, D.1    Ardnor, B.2    Oman, M.3    Naredi, P.4    Sund, M.5
  • 58
    • 0742305866 scopus 로고    scopus 로고
    • Network Biology: Understanding the Cell’s Functional Organization
    • Barabasi, A. L.; Oltvai, Z. N. Network Biology: Understanding the Cell’s Functional Organization Nat. Rev. Genet. 2004, 5, 101-113 10.1038/nrg1272
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 101-113
    • Barabasi, A.L.1    Oltvai, Z.N.2
  • 59
    • 70349330786 scopus 로고    scopus 로고
    • Disease Signatures Are Robust Across Tissues and Experiments
    • Dudley, J. T.; Tibshirani, R.; Deshpande, T.; Butte, A. J. Disease Signatures Are Robust Across Tissues and Experiments Mol. Syst. Biol. 2009, 5, 307 10.1038/msb.2009.66
    • (2009) Mol. Syst. Biol. , vol.5 , pp. 307
    • Dudley, J.T.1    Tibshirani, R.2    Deshpande, T.3    Butte, A.J.4
  • 61
    • 84866445523 scopus 로고    scopus 로고
    • Pancreatic Stellate Cells: A Starring Role in Normal and Diseased Pancreas
    • Apte, M. V.; Pirola, R. C.; Wilson, J. S. Pancreatic Stellate Cells: A Starring Role in Normal and Diseased Pancreas Front. Physiol. 2012, 3, 344 10.3389/fphys.2012.00344
    • (2012) Front. Physiol. , vol.3 , pp. 344
    • Apte, M.V.1    Pirola, R.C.2    Wilson, J.S.3
  • 62
    • 84855966721 scopus 로고    scopus 로고
    • Role of Endoplasmic Reticulum Stress in Metabolic Disease and Other Sisorders
    • Ozcan, L.; Tabas, I. Role of Endoplasmic Reticulum Stress in Metabolic Disease and Other Sisorders Annu. Rev. Med. 2012, 63, 317-328 10.1146/annurev-med-043010-144749
    • (2012) Annu. Rev. Med. , vol.63 , pp. 317-328
    • Ozcan, L.1    Tabas, I.2
  • 64
    • 80053180372 scopus 로고    scopus 로고
    • Mechanism of Anti-Angiogenic Property of Gold Nanoparticles: Role of Nanoparticle Size and Surface Charge
    • Arvizo, R. R.; Rana, S.; Miranda, O. R.; Bhattacharya, R.; Rotello, V. M.; Mukherjee, P. Mechanism of Anti-Angiogenic Property of Gold Nanoparticles: Role of Nanoparticle Size and Surface Charge Nanomedicine 2011, 7, 580-587 10.1016/j.nano.2011.01.011
    • (2011) Nanomedicine , vol.7 , pp. 580-587
    • Arvizo, R.R.1    Rana, S.2    Miranda, O.R.3    Bhattacharya, R.4    Rotello, V.M.5    Mukherjee, P.6
  • 67
    • 13944252976 scopus 로고    scopus 로고
    • A measure of betweenness centrality based on random walks
    • Newman, M. E. J. A measure of betweenness centrality based on random walks Social Networks 2005, 27, 39-54 10.1016/j.socnet.2004.11.009
    • (2005) Social Networks , vol.27 , pp. 39-54
    • Newman, M.E.J.1
  • 68
    • 0035648637 scopus 로고    scopus 로고
    • A Faster Algorithm for Betweenness Centrality
    • Brandes, U. A Faster Algorithm for Betweenness Centrality J. Math. Sociol. 2001, 25, 163-177 10.1080/0022250X.2001.9990249
    • (2001) J. Math. Sociol. , vol.25 , pp. 163-177
    • Brandes, U.1
  • 69
    • 0035799707 scopus 로고    scopus 로고
    • Lethality and Centrality in Protein Networks
    • Jeong, H.; Mason, S. P.; Barabasi, A. L.; Oltvai, Z. N. Lethality and Centrality in Protein Networks Nature 2001, 411, 41-42 10.1038/35075138
    • (2001) Nature , vol.411 , pp. 41-42
    • Jeong, H.1    Mason, S.P.2    Barabasi, A.L.3    Oltvai, Z.N.4
  • 70
    • 33845357608 scopus 로고    scopus 로고
    • An Algorithm for Modularity Analysis of Directed and Weighted Biological Networks Based on Edge-Betweenness Centrality
    • Yoon, J.; Blumer, A.; Lee, K. An Algorithm for Modularity Analysis of Directed and Weighted Biological Networks Based on Edge-Betweenness Centrality Bioinformatics 2006, 22, 3106-3108 10.1093/bioinformatics/btl533
    • (2006) Bioinformatics , vol.22 , pp. 3106-3108
    • Yoon, J.1    Blumer, A.2    Lee, K.3
  • 71
    • 84861779036 scopus 로고    scopus 로고
    • Topological Analysis and Interactive Visualization of Biological Networks and Protein Structures
    • Doncheva, N. T.; Assenov, Y.; Domingues, F. S.; Albrecht, M. Topological Analysis and Interactive Visualization of Biological Networks and Protein Structures Nat. Protoc. 2012, 7, 670-685 10.1038/nprot.2012.004
    • (2012) Nat. Protoc. , vol.7 , pp. 670-685
    • Doncheva, N.T.1    Assenov, Y.2    Domingues, F.S.3    Albrecht, M.4


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