A Phase Ib open label, randomized, safety study of SANGUINATE™ in patients with sickle cell anemia

Revista Brasileira de Hematologia e Hemoterapia

Volumn 39, Issue 1, 2017, Pages 20-27

  Misra, Hemant ^a   Bainbridge, James ^a   Berryman, John ^a   Abuchowski, Abraham ^a   Galvez, Kenneth Mauricio ^b   Uribe, Luis Fernando ^c   Hernandez, Angel Luis ^d   Sosa, Nestor Rodolfo ^e  

^a Prolong Pharmaceuticals   (United States)

^b HOSPITAL PABLO TOBÓN URIBE   (Colombia)

^c Fundación Reina Isabel   (Colombia)

^d Fundación BIOS   (Colombia)

^e Pan American Medical Research Institute   (Panama)

Author keywords

Clinical trial; Safety; SANGUINATE; Sickle cell disease

Indexed keywords

ANTISICKLING AGENT; HYDROXYUREA; SANGUINATE; TROPONIN I; UNCLASSIFIED DRUG;

ABDOMINAL PAIN; ADULT; APPLICATION SITE ERYTHEMA; APPLICATION SITE REACTION; ARTHRALGIA; ARTICLE; BACKACHE; BONE PAIN; CHILL; CLINICAL ARTICLE; COMPARATIVE STUDY; CONNECTIVE TISSUE DISEASE; CONTROLLED STUDY; CONTUSION; DIZZINESS; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG SAFETY; EAR DISEASE; ENDOTHELIAL DYSFUNCTION; ERYTHEMA; GASTROINTESTINAL DISEASE; HEADACHE; HEART DISEASE; HEMATOLOGICAL PARAMETERS; HUMAN; INFECTION; INFLUENZA; INJURY; LIMB PAIN; MUSCULOSKELETAL CHEST PAIN; MUSCULOSKELETAL PAIN; NECK PAIN; OPEN STUDY; ORTHOSTATIC HYPOTENSION; OTALGIA; OXYGEN SATURATION DECREASED; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; PRURITUS; PULMONARY HYPERTENSION; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT DISEASE; SICKLE CELL ANEMIA; SIDE EFFECT; TACHYPNEA; THORAX PAIN; TREATMENT OUTCOME; TRICUSPID VALVE DISEASE; UPPER ABDOMINAL PAIN; UPPER RESPIRATORY TRACT INFECTION; VASCULAR DISEASE; VIRUS INFECTION;

EID: 85007557280     PISSN: 15168484     EISSN: 18060870     Source Type: Journal    
DOI: 10.1016/j.bjhh.2016.08.004     Document Type: Article

References (15)

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