Transfusion of hemoglobin-based oxygen carriers in the carboxy state is beneficial during transient focal cerebral ischemia

Journal of Applied Physiology

Volumn 113, Issue 11, 2012, Pages 1709-1717

  Zhang, Jian ^a   Cao, Suyi ^a   Kwansa, Herman ^a   Crafa, Daina ^a   Kibler, Kathleen K ^a   Koehler, Raymond C ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Carbon monoxide; Cerebral blood flow; Pial artery; Rat; Stroke

Indexed keywords

BLOOD SUBSTITUTE; CARBON DIOXIDE; CARBOXYHEMOGLOBIN; DRUG DERIVATIVE; HEMOGLOBIN; MACROGOL DERIVATIVE; NEUROPROTECTIVE AGENT; PEG HEMOGLOBIN; PEG-HEMOGLOBIN;

ANIMAL; ARTICLE; BLOOD; BRAIN; BRAIN ARTERY; BRAIN CIRCULATION; CEREBRAL ARTERY DISEASE; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECT; INTRAVENOUS DRUG ADMINISTRATION; MALE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; RAT; TIME; TRANSIENT ISCHEMIC ATTACK; VASCULARIZATION; VASODILATATION; WISTAR RAT;

ANIMALS; BLOOD SUBSTITUTES; BRAIN; CARBON DIOXIDE; CARBOXYHEMOGLOBIN; CEREBRAL ARTERIES; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; HEMOGLOBINS; INFARCTION, MIDDLE CEREBRAL ARTERY; INFUSIONS, INTRAVENOUS; ISCHEMIC ATTACK, TRANSIENT; MALE; NEUROPROTECTIVE AGENTS; POLYETHYLENE GLYCOLS; RATS; RATS, WISTAR; TIME FACTORS; VASODILATION;

EID: 84870406409     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01079.2012     Document Type: Article

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