The role of heparan sulfate deficiency in autistic phenotype: Potential involvement of Slit/Robo/srGAPs-mediated dendritic spine formation

Neural Development

Volumn 11, Issue 1, 2016, Pages

  P�rez, Christine ^a   Sawmiller, Darrell ^a   Tan, Jun ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Autism spectrum disorders; Axonal guidance; Dendritic spines; Glycosoaminoglycans; Heparan sulfate; Neurogenesis; Robo; Slit; SrGAPs; Sulfotranferases

Indexed keywords

AGRIN; ARYL SULFOTRANSFERASE; EPHRIN RECEPTOR A3; GLUTATHIONE; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; HEPARAN SULFATE; PERLECAN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; ROUNDABOUT RECEPTOR; SEMAPHORIN; SLIT PROTEIN; SLIT ROBO GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; UNCLASSIFIED DRUG; IMMUNOGLOBULIN RECEPTOR; NERVE PROTEIN; SLIT1 PROTEIN, HUMAN; SRGAP1 PROTEIN, HUMAN; SRGAP2 PROTEIN, HUMAN;

ACTIN FILAMENT; AUTISM; CELL DAMAGE; DENDRITIC SPINE; DEPOLYMERIZATION; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; NERVOUS SYSTEM DEVELOPMENT; PHENOTYPE; PRIORITY JOURNAL; REVIEW; ABNORMALITIES; ANIMAL; BRAIN; DEFICIENCY; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; AUTISM SPECTRUM DISORDER; BRAIN; DENDRITIC SPINES; GTPASE-ACTIVATING PROTEINS; HEPARITIN SULFATE; HUMANS; NERVE TISSUE PROTEINS; PHENOTYPE; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION;

EID: 85007499604     PISSN: None     EISSN: 17498104     Source Type: Journal    
DOI: 10.1186/S13064-016-0066-X     Document Type: Review

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