Identification, characterization and molecular adaptation of class I redox systems for the production of hydroxylated diterpenoids

Microbial Cell Factories

Volumn 15, Issue 1, 2016, Pages

  Görner, Christian ^a   Schrepfer, Patrick ^a   Redai, Veronika ^a   Wallrapp, Frank ^a   Loll, Bernhard ^b   Eisenreich, Wolfgang ^a   Haslbeck, Martin ^a   Brück, Thomas ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Cyclooctatin; Diterpene biosynthesis; Redox system; Sinularcasbane D; Streptomyces afghaniensis

Indexed keywords

CYCLOOCTATIN; CYTOCHROME P450; CYTOCHROME P450 COTB3; CYTOCHROME P450 COTB4; DITERPENOID; FERREDOXIN; FERREDOXIN NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCTASE; OXIDOREDUCTASE; SINULARCASBANE D; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; DITERPENE;

ADAPTATION; ARTICLE; BATCH FERMENTATION; BIOINFORMATICS; BIOSYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME RECONSTITUTION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; GENETIC ENGINEERING AND GENE TECHNOLOGY; HYDROGEN BOND; HYDROXYLATION; NONHUMAN; OXIDATION REDUCTION REACTION; PSEUDOMONAS PUTIDA; STREPTOMYCES; STREPTOMYCES AFGHANIENSIS; BINDING SITE; CHEMISTRY; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR DOCKING; PLASMID; PROTEIN TERTIARY STRUCTURE;

BACTERIAL PROTEINS; BINDING SITES; DITERPENES; ESCHERICHIA COLI; FERREDOXINS; HYDROGEN BONDING; HYDROXYLATION; MOLECULAR DOCKING SIMULATION; OXIDATION-REDUCTION; OXIDOREDUCTASES; PLASMIDS; PROTEIN STRUCTURE, TERTIARY; STREPTOMYCES; SUBSTRATE SPECIFICITY;

EID: 85007425772     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-016-0487-6     Document Type: Article

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