Rationale and design of a randomized trial to test the safety and non-inferiority of canagliflozin in patients with diabetes with chronic heart failure: The CANDLE trial

Cardiovascular Diabetology

Volumn 15, Issue 1, 2016, Pages

  Tanaka, Atsushi ^a   Inoue, Teruo ^b   Kitakaze, Masafumi ^c   Oyama, Jun ichi ^a   Sata, Masataka ^d   Taguchi, Isao ^b   Shimizu, Wataru ^e   Watada, Hirotaka ^f   Tomiyama, Hirofumi ^g   Ako, Junya ^h   Sakata, Yasushi ⁱ   Anzai, Toshihisa ^c   Uematsu, Masaaki ^j   Suzuki, Makoto ^k   Eguchi, Kazuo ^l   Yamashina, Akira ^g   Saito, Yoshihiko ^m   Sato, Yasunori ⁿ   Ueda, Shinichiro ^o   Murohara, Toyoaki ^p   Node, Koichi ^a   more..

^a SAGA UNIVERSITY   (Japan)

^b DOKKYO MEDICAL UNIVERSITY   (Japan)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^d UNIVERSITY OF TOKUSHIMA   (Japan)

^e NIPPON MEDICAL SCHOOL   (Japan)

^f JUNTENDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g TOKYO MEDICAL UNIVERSITY   (Japan)

^h KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

ⁱ OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^j KANSAI ROSAI HOSPITAL   (Japan)

^k KAMEDA MEDICAL CENTER   (Japan)

^l JICHI MEDICAL UNIVERSITY   (Japan)

^m NARA MEDICAL UNIVERSITY   (Japan)

ⁿ CHIBA UNIVERSITY   (Japan)

^o UNIVERSITY OF THE RYUKYUS SCHOOL OF MEDICINE   (Japan)

^p NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

more..

Author keywords

Canagliflozin; Chronic heart failure; Glimepiride; Non inferiority; NT proBNP; Safety; SGLT2 inhibitor; Type 2 diabetes mellitus

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; CANAGLIFLOZIN; GLIMEPIRIDE; HEMOGLOBIN A1C; ANTIDIABETIC AGENT; BENZHYDRYL DERIVATIVE; EMPAGLIFLOZIN; GLUCOSE BLOOD LEVEL; GLUCOSIDE; METFORMIN; SULFONYLUREA DERIVATIVE;

ADULT; AGE; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; CARDIOVASCULAR RISK; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; GLYCEMIC CONTROL; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; KIDNEY FUNCTION; LIPID ANALYSIS; MAJOR CLINICAL STUDY; MALE; NEW YORK HEART ASSOCIATION CLASS; NON INSULIN DEPENDENT DIABETES MELLITUS; QUALITY OF LIFE ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION; AGED; BLOOD; CHRONIC DISEASE; DIABETES MELLITUS, TYPE 2; DRUG EFFECTS; GLUCOSE BLOOD LEVEL; MIDDLE AGED; QUALITY OF LIFE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BENZHYDRYL COMPOUNDS; BLOOD GLUCOSE; BLOOD PRESSURE; CANAGLIFLOZIN; CHRONIC DISEASE; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCOSIDES; HEART FAILURE; HUMANS; HYPOGLYCEMIC AGENTS; MALE; METFORMIN; MIDDLE AGED; QUALITY OF LIFE; SULFONYLUREA COMPOUNDS;

EID: 85007418008     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/s12933-016-0381-x     Document Type: Article

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