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Volumn 130, Issue 2, 2017, Pages 173-187

Role of Niacin in Current Clinical Practice: A Systematic Review

Author keywords

Cardiovascular risk; High density lipoprotein cholesterol; Niacin

Indexed keywords

CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NICOTINIC ACID; ANTILIPEMIC AGENT;

EID: 85007406957     PISSN: 00029343     EISSN: 15557162     Source Type: Journal    
DOI: 10.1016/j.amjmed.2016.07.038     Document Type: Article
Times cited : (67)

References (55)
  • 1
    • 84922357714 scopus 로고    scopus 로고
    • Executive summary: heart disease and stroke statistics-2015 update: a report from the American Heart Association
    • 1 Executive summary: heart disease and stroke statistics-2015 update: a report from the American Heart Association. Circulation 131:4 (2015), 434–441.
    • (2015) Circulation , vol.131 , Issue.4 , pp. 434-441
  • 2
    • 0023710312 scopus 로고
    • Cholesterol and lipids in the risk of coronary artery disease—the Framingham Heart Study
    • 2 Castelli, W.P., Cholesterol and lipids in the risk of coronary artery disease—the Framingham Heart Study. Can J Cardiol 4:suppl (1988), 5A–10A.
    • (1988) Can J Cardiol , vol.4 , pp. 5A-10A
    • Castelli, W.P.1
  • 3
    • 0025376017 scopus 로고
    • Ten-year mortality from cardiovascular disease in relation to cholesterol level among men with and without preexisting cardiovascular disease
    • 3 Pekkanen, J., Linn, S., Heiss, G., et al. Ten-year mortality from cardiovascular disease in relation to cholesterol level among men with and without preexisting cardiovascular disease. N Engl J Med 322:24 (1990), 1700–1707.
    • (1990) N Engl J Med , vol.322 , Issue.24 , pp. 1700-1707
    • Pekkanen, J.1    Linn, S.2    Heiss, G.3
  • 4
    • 70450081001 scopus 로고    scopus 로고
    • Major lipids, apolipoproteins, and risk of vascular disease
    • 4 Di Angelantonio, E., Sarwar, N., Perry, P., Major lipids, apolipoproteins, and risk of vascular disease. JAMA 302 (2009), 1993–2000.
    • (2009) JAMA , vol.302 , pp. 1993-2000
    • Di Angelantonio, E.1    Sarwar, N.2    Perry, P.3
  • 5
    • 84912106277 scopus 로고    scopus 로고
    • Long-term risk of cardiovascular events across a spectrum of adverse major plasma lipid combinations in the Framingham Heart Study
    • 5 Andersson, C., Lyass, A., Vasan, R.S., Massaro, J.M., D'Agostino, R.B. Sr., Robins, S.J., Long-term risk of cardiovascular events across a spectrum of adverse major plasma lipid combinations in the Framingham Heart Study. Am Heart J 168:6 (2014), 878–883.
    • (2014) Am Heart J , vol.168 , Issue.6 , pp. 878-883
    • Andersson, C.1    Lyass, A.2    Vasan, R.S.3    Massaro, J.M.4    D'Agostino, R.B.5    Robins, S.J.6
  • 6
    • 0032572086 scopus 로고    scopus 로고
    • Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study
    • 6 Downs, J.R., Clearfield, M., Weis, S., et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study. JAMA 279:20 (1998), 1615–1622.
    • (1998) JAMA , vol.279 , Issue.20 , pp. 1615-1622
    • Downs, J.R.1    Clearfield, M.2    Weis, S.3
  • 7
    • 11144355354 scopus 로고    scopus 로고
    • Intensive versus moderate lipid lowering with statins after acute coronary syndromes
    • 7 Cannon, C.P., Braunwald, E., McCabe, C.H., et al. Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N Engl J Med 350:15 (2004), 1495–1504.
    • (2004) N Engl J Med , vol.350 , Issue.15 , pp. 1495-1504
    • Cannon, C.P.1    Braunwald, E.2    McCabe, C.H.3
  • 8
    • 78449281377 scopus 로고    scopus 로고
    • Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials
    • 8 Cholesterol Treatment Trialist (CTT) Collaboration. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet 376 (2010), 1670–1681.
    • (2010) Lancet , vol.376 , pp. 1670-1681
  • 9
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
    • 9 Baigent, C., Keech, A., Kearney, P.M., et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet 366:9493 (2005), 1267–1278.
    • (2005) Lancet , vol.366 , Issue.9493 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3
  • 10
    • 84897970506 scopus 로고    scopus 로고
    • 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
    • 10 American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 129:25 suppl 2 (2014), S1–S45.
    • (2014) Circulation , vol.129 , Issue.25 , pp. S1-S45
  • 11
    • 84908397421 scopus 로고    scopus 로고
    • National Lipid Association recommendations for patient-centered management of dyslipidemia: part 1—executive summary
    • 11 Jacobson, T.A., Ito, M.K., Maki, K.C., et al. National Lipid Association recommendations for patient-centered management of dyslipidemia: part 1—executive summary. J Clin Lipidol 8:5 (2014), 473–488.
    • (2014) J Clin Lipidol , vol.8 , Issue.5 , pp. 473-488
    • Jacobson, T.A.1    Ito, M.K.2    Maki, K.C.3
  • 12
    • 84905189482 scopus 로고    scopus 로고
    • Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: a meta-analysis of statin trials
    • 12 Boekholdt, S.M., Hovingh, G.K., Mora, S., et al. Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: a meta-analysis of statin trials. J Am Coll Cardiol 64:5 (2014), 485–494.
    • (2014) J Am Coll Cardiol , vol.64 , Issue.5 , pp. 485-494
    • Boekholdt, S.M.1    Hovingh, G.K.2    Mora, S.3
  • 13
    • 4544243333 scopus 로고    scopus 로고
    • Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes: phase Z of the A to Z trial
    • 13 de Lemos, J.A., Blazing, M.A., Wiviott, S.D., et al. Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes: phase Z of the A to Z trial. JAMA 292 (2004), 1307–1316.
    • (2004) JAMA , vol.292 , pp. 1307-1316
    • de Lemos, J.A.1    Blazing, M.A.2    Wiviott, S.D.3
  • 14
    • 34748887666 scopus 로고    scopus 로고
    • HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events
    • 14 Barter, P., Gotto, A.M., LaRosa, J.C., et al. HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events. N Engl J Med 357:13 (2007), 1301–1310.
    • (2007) N Engl J Med , vol.357 , Issue.13 , pp. 1301-1310
    • Barter, P.1    Gotto, A.M.2    LaRosa, J.C.3
  • 15
    • 78751640788 scopus 로고    scopus 로고
    • Meta-analysis: statin therapy does not alter the association between low levels of high-density lipoprotein cholesterol and increased cardiovascular risk
    • 15 Jafri, H., Alsheikh-Ali, A.A., Karas, R.H., Meta-analysis: statin therapy does not alter the association between low levels of high-density lipoprotein cholesterol and increased cardiovascular risk. Ann Intern Med 153:12 (2010), 800–808.
    • (2010) Ann Intern Med , vol.153 , Issue.12 , pp. 800-808
    • Jafri, H.1    Alsheikh-Ali, A.A.2    Karas, R.H.3
  • 16
    • 84887150818 scopus 로고    scopus 로고
    • Low levels of high-density lipoprotein cholesterol and increased risk of cardiovascular events in stable ischemic heart disease patients: a post-hoc analysis from the COURAGE trial (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation)
    • 16 Acharjee, S., Boden, W.E., Hartigan, P.M., et al. Low levels of high-density lipoprotein cholesterol and increased risk of cardiovascular events in stable ischemic heart disease patients: a post-hoc analysis from the COURAGE trial (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation). J Am Coll Cardiol 62:20 (2013), 1826–1833.
    • (2013) J Am Coll Cardiol , vol.62 , Issue.20 , pp. 1826-1833
    • Acharjee, S.1    Boden, W.E.2    Hartigan, P.M.3
  • 17
    • 0031029838 scopus 로고    scopus 로고
    • Isolated low HDL cholesterol as a risk factor for coronary heart disease mortality: a 21-year follow-up of 8000 men
    • 17 Goldbourt, U., Yaari, S., Medalie, J.H., Isolated low HDL cholesterol as a risk factor for coronary heart disease mortality: a 21-year follow-up of 8000 men. Arterioscler Thromb Vasc Biol 17 (1997), 107–113.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 107-113
    • Goldbourt, U.1    Yaari, S.2    Medalie, J.H.3
  • 18
    • 0026091744 scopus 로고
    • A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction
    • 18 Stampfer, M.J., Sacks, F.M., Salvini, S., Willett, W.C., Hennekens, C.H., A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction. N Engl J Med 325:6 (1991), 373–381.
    • (1991) N Engl J Med , vol.325 , Issue.6 , pp. 373-381
    • Stampfer, M.J.1    Sacks, F.M.2    Salvini, S.3    Willett, W.C.4    Hennekens, C.H.5
  • 19
    • 0033527030 scopus 로고    scopus 로고
    • Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol
    • 19 Rubins, H.B., Robins, S.J., Collins, D., et al. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. N Engl J Med 341 (1999), 410–418.
    • (1999) N Engl J Med , vol.341 , pp. 410-418
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3
  • 20
    • 41149175907 scopus 로고    scopus 로고
    • Mechanism of action of niacin
    • 20 Kamanna, V.S., Kashyap, M.L., Mechanism of action of niacin. Am J Cardiol 101 (2008), 20B–26B.
    • (2008) Am J Cardiol , vol.101 , pp. 20B-26B
    • Kamanna, V.S.1    Kashyap, M.L.2
  • 21
    • 0016630250 scopus 로고
    • Clofibrate and niacin in coronary heart disease
    • 21 The Coronary Drug Project Research Group. Clofibrate and niacin in coronary heart disease. JAMA 231 (1975), 360–381.
    • (1975) JAMA , vol.231 , pp. 360-381
  • 22
    • 10044281651 scopus 로고    scopus 로고
    • Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins
    • 22 Taylor, A.J., Sullenberger, L.E., Lee, H.J., Lee, J.K., Grace, K.A., Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins. Circulation 110 (2004), 3512–3517.
    • (2004) Circulation , vol.110 , pp. 3512-3517
    • Taylor, A.J.1    Sullenberger, L.E.2    Lee, H.J.3    Lee, J.K.4    Grace, K.A.5
  • 23
    • 84855171302 scopus 로고    scopus 로고
    • Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy
    • 23 A.I.M.-H.I.G.H. Investigators, Boden, W.E., Probstfield, J.L., et al. Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. N Engl J Med 365:24 (2011), 2255–2267.
    • (2011) N Engl J Med , vol.365 , Issue.24 , pp. 2255-2267
    • Boden, W.E.1    Probstfield, J.L.2
  • 24
    • 84904252744 scopus 로고    scopus 로고
    • Effects of extended-release niacin with laropiprant in high-risk patients
    • 24 HPS2-THRIVE Collaborative Group, Landray, M.J., Haynes, R., Hopewell, J.C., et al. Effects of extended-release niacin with laropiprant in high-risk patients. N Engl J Med 371:3 (2014), 203–212.
    • (2014) N Engl J Med , vol.371 , Issue.3 , pp. 203-212
    • Landray, M.J.1    Haynes, R.2    Hopewell, J.C.3
  • 25
    • 68049122102 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
    • 25 Moher, D., Liberati, A., Tetzlaff, J., Altman, D.G., The PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med, 6(6), 2009, e1000097.
    • (2009) PLoS Med , vol.6 , Issue.6 , pp. e1000097
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 26
    • 0025685469 scopus 로고
    • Regression of coronary atherosclerosis during treatment of familial hypercholesterolemia with combined drug regimens
    • 26 Kane, J.P., Malloy, M.J., Ports, T.A., Phillips, N.R., Diehl, J.C., Havel, R.J., Regression of coronary atherosclerosis during treatment of familial hypercholesterolemia with combined drug regimens. JAMA 264 (1990), 3007–3012.
    • (1990) JAMA , vol.264 , pp. 3007-3012
    • Kane, J.P.1    Malloy, M.J.2    Ports, T.A.3    Phillips, N.R.4    Diehl, J.C.5    Havel, R.J.6
  • 27
    • 84948007950 scopus 로고
    • Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts
    • 27 Blankenhorn, D.H., Nessim, S.A., Johnson, R.L., Sanmarco, M.E., Azen, S.P., Cashin-Hemphill, L., Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts. JAMA 257 (1987), 3233–3240.
    • (1987) JAMA , vol.257 , pp. 3233-3240
    • Blankenhorn, D.H.1    Nessim, S.A.2    Johnson, R.L.3    Sanmarco, M.E.4    Azen, S.P.5    Cashin-Hemphill, L.6
  • 28
    • 0025183769 scopus 로고
    • Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B
    • 28 Brown, G., Albers, J.J., Fisher, L.D., et al. Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B. N Engl J Med 323:19 (1990), 1289–1298.
    • (1990) N Engl J Med , vol.323 , Issue.19 , pp. 1289-1298
    • Brown, G.1    Albers, J.J.2    Fisher, L.D.3
  • 29
    • 19944426989 scopus 로고    scopus 로고
    • A randomized trial of a strategy for increasing high-density lipoprotein cholesterol levels: effects on progression of coronary heart disease and clinical events
    • 29 Whitney, E.J., Krasuski, R.A., Personius, B.E., et al. A randomized trial of a strategy for increasing high-density lipoprotein cholesterol levels: effects on progression of coronary heart disease and clinical events. Ann Intern Med 142 (2005), 95–104.
    • (2005) Ann Intern Med , vol.142 , pp. 95-104
    • Whitney, E.J.1    Krasuski, R.A.2    Personius, B.E.3
  • 30
    • 0023910325 scopus 로고
    • Reduction of mortality in the Stockholm Ischaemic Heart Disease Secondary Prevention Study by combined treatment with clofibrate and nicotinic acid
    • 30 Carlson, L.A., Rosenhamer, G., Reduction of mortality in the Stockholm Ischaemic Heart Disease Secondary Prevention Study by combined treatment with clofibrate and nicotinic acid. Acta Med Scand 223 (1988), 405–418.
    • (1988) Acta Med Scand , vol.223 , pp. 405-418
    • Carlson, L.A.1    Rosenhamer, G.2
  • 31
    • 0035969564 scopus 로고    scopus 로고
    • Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease
    • 31 Brown, B.G., Xue-Qiao, Z., Chait, A., et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 345 (2001), 1583–1592.
    • (2001) N Engl J Med , vol.345 , pp. 1583-1592
    • Brown, B.G.1    Xue-Qiao, Z.2    Chait, A.3
  • 32
    • 72049129430 scopus 로고    scopus 로고
    • Extended-release niacin or ezetimibe and carotid intima-media thickness
    • 32 Taylor, A.J., Villines, T.C., Stanek, E.J., et al. Extended-release niacin or ezetimibe and carotid intima-media thickness. N Engl J Med 361:22 (2009), 2113–2122.
    • (2009) N Engl J Med , vol.361 , Issue.22 , pp. 2113-2122
    • Taylor, A.J.1    Villines, T.C.2    Stanek, E.J.3
  • 33
    • 41949131921 scopus 로고    scopus 로고
    • Lipid-altering efficacy and safety of ezetimibe/simvastatin coadministered with extended-release niacin in patients with type IIa or type IIb hyperlipidemia
    • 33 Guyton, J.R., Brown, B.G., Fazio, S., Polis, A., Tomassini, J.E., Tershakovec, A.M., Lipid-altering efficacy and safety of ezetimibe/simvastatin coadministered with extended-release niacin in patients with type IIa or type IIb hyperlipidemia. J Am Coll Cardiol, 51, 2008, 1564e72.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1564e72
    • Guyton, J.R.1    Brown, B.G.2    Fazio, S.3    Polis, A.4    Tomassini, J.E.5    Tershakovec, A.M.6
  • 34
    • 70349554061 scopus 로고    scopus 로고
    • Combined use of extended-release niacin and atorvastatin: safety and effects on lipid modification
    • 34 Sang, Z.C., Wang, F., Zhou, Q., et al. Combined use of extended-release niacin and atorvastatin: safety and effects on lipid modification. Chin Med J (Engl) 122 (2009), 1615–1620.
    • (2009) Chin Med J (Engl) , vol.122 , pp. 1615-1620
    • Sang, Z.C.1    Wang, F.2    Zhou, Q.3
  • 35
    • 15944410609 scopus 로고    scopus 로고
    • Intensive lipid lowering with atorvastatin in patients with stable coronary disease
    • 35 LaRosa, J.C., Grundy, S.M., Waters, D.D., et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med 352:14 (2005), 1425–1435.
    • (2005) N Engl J Med , vol.352 , Issue.14 , pp. 1425-1435
    • LaRosa, J.C.1    Grundy, S.M.2    Waters, D.D.3
  • 36
    • 0017384270 scopus 로고
    • High-density lipoprotein as a protective factor against coronary heart disease: the Framingham Study
    • 36 Gordon, T., Castelli, W.P., Hjortland, M.C., Kannel, W.B., Dawber, T.R., High-density lipoprotein as a protective factor against coronary heart disease: the Framingham Study. Am J Med 62 (1977), 707–714.
    • (1977) Am J Med , vol.62 , pp. 707-714
    • Gordon, T.1    Castelli, W.P.2    Hjortland, M.C.3    Kannel, W.B.4    Dawber, T.R.5
  • 37
    • 61549120401 scopus 로고    scopus 로고
    • Prognostic utility of apoB/AI, total cholesterol/HDL, non-HDL cholesterol, or hs-CRP as predictors of clinical risk in patients receiving statin therapy after acute coronary syndromes: results from PROVE IT-TIMI 22
    • 37 Ray, K.K., Cannon, C.P., Cairns, R., Morrow, D.A., Ridker, P.M., Braunwald, E., Prognostic utility of apoB/AI, total cholesterol/HDL, non-HDL cholesterol, or hs-CRP as predictors of clinical risk in patients receiving statin therapy after acute coronary syndromes: results from PROVE IT-TIMI 22. Arterioscler Thromb Vasc Biol 29:3 (2009), 424–430.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , Issue.3 , pp. 424-430
    • Ray, K.K.1    Cannon, C.P.2    Cairns, R.3    Morrow, D.A.4    Ridker, P.M.5    Braunwald, E.6
  • 38
    • 77955712458 scopus 로고    scopus 로고
    • HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial
    • 38 Ridker, P.M., Genest, J., Boekholdt, S.M., et al. HDL cholesterol and residual risk of first cardiovascular events after treatment with potent statin therapy: an analysis from the JUPITER trial. Lancet 376:9738 (2010), 333–339.
    • (2010) Lancet , vol.376 , Issue.9738 , pp. 333-339
    • Ridker, P.M.1    Genest, J.2    Boekholdt, S.M.3
  • 39
    • 0023001772 scopus 로고
    • Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin
    • 39 Canner, P.L., Berge, K.G., Wenger, N.K., et al. Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin. J Am Coll Cardiol 8 (1986), 1245–1255.
    • (1986) J Am Coll Cardiol , vol.8 , pp. 1245-1255
    • Canner, P.L.1    Berge, K.G.2    Wenger, N.K.3
  • 40
    • 77951928738 scopus 로고    scopus 로고
    • Effect of niacin therapy on cardiovascular outcomes in patients with coronary artery disease
    • 40 Duggal, J.K., Singh, M., Attri, N., et al. Effect of niacin therapy on cardiovascular outcomes in patients with coronary artery disease. J Cardiovasc Pharmacol Ther 15 (2010), 158–166.
    • (2010) J Cardiovasc Pharmacol Ther , vol.15 , pp. 158-166
    • Duggal, J.K.1    Singh, M.2    Attri, N.3
  • 41
    • 77952397461 scopus 로고    scopus 로고
    • Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis
    • 41 Bruckert, E., Labreuche, J., Amarenco, P., Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis. Atherosclerosis 210:2 (2010), 353–361.
    • (2010) Atherosclerosis , vol.210 , Issue.2 , pp. 353-361
    • Bruckert, E.1    Labreuche, J.2    Amarenco, P.3
  • 42
    • 84904490497 scopus 로고    scopus 로고
    • Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
    • 42 Keene, D., Price, C., Shun-Shin, M.J., Francis, D.P., Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients. BMJ, 349, 2014, g4379.
    • (2014) BMJ , vol.349 , pp. g4379
    • Keene, D.1    Price, C.2    Shun-Shin, M.J.3    Francis, D.P.4
  • 43
    • 84872679028 scopus 로고    scopus 로고
    • The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression
    • 43 Lavigne, P.M., Karas, R.H., The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression. J Am Coll Cardiol 61:4 (2013), 440–446.
    • (2013) J Am Coll Cardiol , vol.61 , Issue.4 , pp. 440-446
    • Lavigne, P.M.1    Karas, R.H.2
  • 44
    • 84958719174 scopus 로고    scopus 로고
    • The beneficial effects of raising high-density lipoprotein cholesterol depends upon achieved levels of low-density lipoprotein cholesterol during statin therapy: implications for coronary atheroma progression and cardiovascular events
    • 44 Puri, R., Nissen, S.E., Shao, M., et al. The beneficial effects of raising high-density lipoprotein cholesterol depends upon achieved levels of low-density lipoprotein cholesterol during statin therapy: implications for coronary atheroma progression and cardiovascular events. Eur J Prev Cardiol 23:5 (2016), 474–485.
    • (2016) Eur J Prev Cardiol , vol.23 , Issue.5 , pp. 474-485
    • Puri, R.1    Nissen, S.E.2    Shao, M.3
  • 45
    • 84884322622 scopus 로고    scopus 로고
    • High-density lipoprotein cholesterol, size, particle number, and residual vascular risk after potent statin therapy
    • 45 Mora, S., Glynn, R.J., Ridker, P.M., High-density lipoprotein cholesterol, size, particle number, and residual vascular risk after potent statin therapy. Circulation 128 (2013), 1189–1197.
    • (2013) Circulation , vol.128 , pp. 1189-1197
    • Mora, S.1    Glynn, R.J.2    Ridker, P.M.3
  • 46
    • 33645741889 scopus 로고    scopus 로고
    • Low-density lipoprotein and high-density lipoprotein particle subclasses predict coronary events and are favorably changed by gemfibrozil therapy in the Veterans Affairs High-Density Lipoprotein Intervention Trial
    • 46 Otvos, J.D., Collins, D., Freedman, D.S., et al. Low-density lipoprotein and high-density lipoprotein particle subclasses predict coronary events and are favorably changed by gemfibrozil therapy in the Veterans Affairs High-Density Lipoprotein Intervention Trial. Circulation 113 (2006), 1556–1563.
    • (2006) Circulation , vol.113 , pp. 1556-1563
    • Otvos, J.D.1    Collins, D.2    Freedman, D.S.3
  • 47
    • 84885844867 scopus 로고    scopus 로고
    • The addition of niacin to statin therapy improves high-density lipoprotein cholesterol levels but not metrics of functionality
    • 47 Khera, A.V., Patel, P.J., Reilly, M.P., Rader, D.J., The addition of niacin to statin therapy improves high-density lipoprotein cholesterol levels but not metrics of functionality. J Am Coll Cardiol 62:20 (2013), 1909–1910.
    • (2013) J Am Coll Cardiol , vol.62 , Issue.20 , pp. 1909-1910
    • Khera, A.V.1    Patel, P.J.2    Reilly, M.P.3    Rader, D.J.4
  • 48
    • 84919343998 scopus 로고    scopus 로고
    • HDL cholesterol efflux capacity and incident cardiovascular events
    • 48 Rohatgi, A., Khera, A., Berry, J.D., et al. HDL cholesterol efflux capacity and incident cardiovascular events. N Engl J Med 371:25 (2014), 2383–2393.
    • (2014) N Engl J Med , vol.371 , Issue.25 , pp. 2383-2393
    • Rohatgi, A.1    Khera, A.2    Berry, J.D.3
  • 49
    • 84955662453 scopus 로고    scopus 로고
    • Extended-release niacin/laropiprant improves overall efficacy of postprandial reverse cholesterol transport
    • 49 El Khoury, P., Waldmann, E., Huby, T., et al. Extended-release niacin/laropiprant improves overall efficacy of postprandial reverse cholesterol transport. Arterioscler Thromb Vasc Biol 36:2 (2016), 285–294.
    • (2016) Arterioscler Thromb Vasc Biol , vol.36 , Issue.2 , pp. 285-294
    • El Khoury, P.1    Waldmann, E.2    Huby, T.3
  • 50
    • 84955635473 scopus 로고    scopus 로고
    • Niacin therapy increases high-density lipoprotein particles and total cholesterol efflux capacity but not ABCA1-specific cholesterol efflux in statin-treated subjects
    • 50 Ronsein, G.E., Hutchins, P.M., Isquith, D., et al. Niacin therapy increases high-density lipoprotein particles and total cholesterol efflux capacity but not ABCA1-specific cholesterol efflux in statin-treated subjects. Arterioscler Thromb Vasc Biol 36:2 (2016), 404–411.
    • (2016) Arterioscler Thromb Vasc Biol , vol.36 , Issue.2 , pp. 404-411
    • Ronsein, G.E.1    Hutchins, P.M.2    Isquith, D.3
  • 51
    • 84885022632 scopus 로고    scopus 로고
    • Levels and changes of HDL cholesterol and apolipoprotein A-I in relation to risk of cardiovascular events among statin-treated patients: a meta-analysis
    • 51 Boekholdt, S.M., Arsenault, B.J., Hovingh, G.K., et al. Levels and changes of HDL cholesterol and apolipoprotein A-I in relation to risk of cardiovascular events among statin-treated patients: a meta-analysis. Circulation 128:14 (2013), 1504–1512.
    • (2013) Circulation , vol.128 , Issue.14 , pp. 1504-1512
    • Boekholdt, S.M.1    Arsenault, B.J.2    Hovingh, G.K.3
  • 52
    • 77049084050 scopus 로고    scopus 로고
    • Anti-inflammatory effects of nicotinic acid in adipocytes demonstrated by suppression of fractalkine, RANTES, and MCP-1 and upregulation of adiponectin
    • 52 Digby, J.E., McNeill, E., Dyar, O.J., Lam, V., Greaves, D.R., Choudhury, R.P., Anti-inflammatory effects of nicotinic acid in adipocytes demonstrated by suppression of fractalkine, RANTES, and MCP-1 and upregulation of adiponectin. Atherosclerosis 209 (2010), 89–95.
    • (2010) Atherosclerosis , vol.209 , pp. 89-95
    • Digby, J.E.1    McNeill, E.2    Dyar, O.J.3    Lam, V.4    Greaves, D.R.5    Choudhury, R.P.6
  • 53
    • 34447265547 scopus 로고    scopus 로고
    • Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomised, double-blind trial
    • 53 Bots, M.L., Visseren, F.L., Evans, G.W., et al. Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomised, double-blind trial. Lancet 370 (2007), 153–160.
    • (2007) Lancet , vol.370 , pp. 153-160
    • Bots, M.L.1    Visseren, F.L.2    Evans, G.W.3
  • 54
    • 77951704587 scopus 로고    scopus 로고
    • Effects of combination lipid therapy in type 2 diabetes mellitus
    • 54 ACCORD Study Group, Ginsberg, H.N., Elam, M.B., Lovato, L.C., et al. Effects of combination lipid therapy in type 2 diabetes mellitus. N Engl J Med 362:17 (2010), 1563–1574.
    • (2010) N Engl J Med , vol.362 , Issue.17 , pp. 1563-1574
    • Ginsberg, H.N.1    Elam, M.B.2    Lovato, L.C.3
  • 55
    • 84870045994 scopus 로고    scopus 로고
    • Effects of dalcetrapib in patients with a recent acute coronary syndrome
    • 55 Schwartz, G.G., Olsson, A.G., Abt, M., et al. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med 367:22 (2012), 2089–2099.
    • (2012) N Engl J Med , vol.367 , Issue.22 , pp. 2089-2099
    • Schwartz, G.G.1    Olsson, A.G.2    Abt, M.3


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