High-Throughput Parallel Sequencing to Measure Fitness of Leptospira interrogans Transposon Insertion Mutants during Acute Infection

PLoS Neglected Tropical Diseases

Volumn 10, Issue 11, 2016, Pages

  Lourdault, Kristel ^a,b   Matsunaga, James ^a,b   Haake, David A ^a,b,c  

^a VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; GUANYLATE CYCLASE; SPACER DNA; TRANSPOSON; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL LOAD; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CELL MOTILITY; CONTROLLED STUDY; DNA EXTRACTION; FEMALE; GENE EXPRESSION; GENE LIBRARY; GROWTH CURVE; HAMSTER; HIGH THROUGHPUT SEQUENCING; LEPTOSPIRA INTERROGANS; LEPTOSPIROSIS; MUTAGENESIS; NONHUMAN; POLYMERASE CHAIN REACTION; REPRODUCTIVE FITNESS; RNA EXTRACTION; SIGNAL TRANSDUCTION; TRANSPOSON; WESTERN BLOTTING; ACUTE DISEASE; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; KIDNEY; LIVER; PARASITOLOGY; PATHOGENICITY; VIRULENCE; ZOONOSIS;

ACUTE DISEASE; ANIMALS; CRICETINAE; DNA TRANSPOSABLE ELEMENTS; GENETIC FITNESS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; KIDNEY; LEPTOSPIRA INTERROGANS; LEPTOSPIROSIS; LIVER; MUTAGENESIS, INSERTIONAL; VIRULENCE; VIRULENCE FACTORS; ZOONOSES;

EID: 85007319258     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0005117     Document Type: Article

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