MG53-IRS-1 (mitsugumin 53-insulin receptor substrate-1) interaction disruptor sensitizes insulin signaling in skeletal muscle

Journal of Biological Chemistry

Volumn 291, Issue 52, 2016, Pages 26627-26635

  Lee, Hyun ^a   Park, Jung Jin ^a   Nguyen, Nga ^a   Park, Jun Sub ^a   Hong, Jin ^a   Kim, Seung Hyeob ^a   Song, Woon Young ^a   Kim, Hak Joong ^a   Choi, Kwangman ^b   Cho, Sungchan ^b   Lee, Jae Seon ^c   Kim, Bong Woo ^a   Ko, Young Gyu ^a  

^a Korea University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Inha University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; LUMINESCENCE; MUSCLE;

COMPLEMENTATION; DRUG CANDIDATES; INSULIN RECEPTOR SUBSTRATE-1; INSULIN RESISTANCE; INSULIN SIGNALING; MOLECULAR ASSOCIATIONS; RECEPTOR SUBSTRATES; SKELETAL MUSCLE;

INSULIN;

CAVEOLIN 3; DYSFERLIN; INSULIN RECEPTOR SUBSTRATE 1; MEMBRANE PROTEIN; MITSUGUMIN 53 INSULIN RECEPTOR SUBSTRATE 1 INTERACTION DISRUPTOR; MITSUGUMIN 53 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CARRIER PROTEIN; INSULIN; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, HUMAN; MICROTUBULE PROTEIN; MID1 PROTEIN, HUMAN; MITSUGUMIN 53, HUMAN; MOLECULAR LIBRARY; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; GLUCOSE TRANSPORT; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMMUNOASSAY; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MEMBRANE DAMAGE; MYOTUBE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; UBIQUITINATION; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; INSULIN RESISTANCE; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY; PHOSPHORYLATION; SKELETAL MUSCLE CELL;

CARRIER PROTEINS; CELLS, CULTURED; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MICROTUBULE PROTEINS; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN INTERACTION MAPS; PROTEOLYSIS; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES; TRANSCRIPTION FACTORS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 85007310688     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.754424     Document Type: Article

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