Efficacy of early sivelestat administration on acute lung injury and acute respiratory distress syndrome

Respirology

Volumn 22, Issue 4, 2017, Pages 708-713

  Kido, Takashi ^a   Muramatsu, Keiji ^a   Yatera, Kazuhiro ^a   Asakawa, Takeshi ^a   Otsubo, Hiroki ^a   Kubo, Tatsuhiko ^a   Fujino, Yoshihisa ^a   Matsuda, Shinya ^a   Mayumi, Toshihiko ^a   Mukae, Hiroshi ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

acute lung injury; acute respiratory distress syndrome; inverse probability of treatment weighting; nationwide administrative database; sivelestat

Indexed keywords

METHYLPREDNISOLONE; SIVELESTAT; GLYCINE; SERINE PROTEINASE INHIBITOR; SULFONAMIDE;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; AGE; AGED; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MEGADOSE; FEMALE; HEMODIALYSIS; HUMAN; JAPANESE (PEOPLE); MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASM; OBSERVATIONAL STUDY; PROGNOSIS; RETROSPECTIVE STUDY; SURVIVAL RATE; ANALOGS AND DERIVATIVES; CLINICAL TRIAL; DOSE RESPONSE; DRUG ADMINISTRATION; FOLLOW UP; MULTICENTER STUDY; TIME FACTOR; TREATMENT OUTCOME;

ACUTE LUNG INJURY; AGED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; GLYCINE; HUMANS; MALE; PROGNOSIS; RESPIRATORY DISTRESS SYNDROME, ADULT; RETROSPECTIVE STUDIES; SERINE PROTEINASE INHIBITORS; SULFONAMIDES; TIME FACTORS; TREATMENT OUTCOME;

EID: 85007236253     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/resp.12969     Document Type: Article

References (30)

1. The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N. Engl. J. Med. 2000; 342: 1301–8.
2. Zambon M, Vincent JL. Mortality rates for patients with acute lung injury/ARDS have decreased over time. Chest 2008; 133: 1120–7.
3. Briel M, Meade M, Mercat A, Brower RG, Talmor D, Walter SD, Slutsky AS, Pullenayegum E, Zhou Q, Cook D et al. Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis. JAMA 2010; 303: 865–73.
4. Guerin C, Reignier J, Richard JC, Beuret P, Gacouin A, Boulain T, Mercier E, Badet M, Mercat A, Baudin O et al. Prone positioning in severe acute respiratory distress syndrome. N. Engl. J. Med. 2013; 368: 2159–68.
5. Phua J, Badia JR, Adhikari NK, Friedrich JO, Fowler RA, Singh JM, Scales DC, Stather DR, Li A, Jones A et al. Has mortality from acute respiratory distress syndrome decreased over time?: A systematic review. Am. J. Respir. Crit. Care Med. 2009; 179: 220–7.
6. Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, Lamy M, Legall JR, Morris A, Spragg R. The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am. J. Respir. Crit. Care Med. 1994; 149: 818–24.
7. Zeiher BG, Artigas A, Vincent J-L, Dmitrienko A, Jackson K, Thompson BT, Bernard G. Neutrophil elastase inhibition in acute lung injury: results of the STRIVE study. Crit. Care Med. 2004; 32: 1695–702.
8. Kawabata K, Suzuki M, Sugitani M, Imaki K, Toda M, Miyamoto T. ONO-5046, a novel inhibitor of human neutrophil elastase. Biochem. Biophys. Res. Commun. 1991; 177: 814–20.
9. Iba T, Kidokoro A, Fukunaga M, Takuhiro K, Yoshikawa S, Sugimotoa K. Pretreatment of sivelestat sodium hydrate improves the lung microcirculation and alveolar damage in lipopolysaccharide-induced acute lung inflammation in hamsters. Shock 2006; 26: 95–8.
10. Tagami T, Tosa R, Omura M, Fukushima H, Kaneko T, Endo T, Rinka H, Murai A, Yamaguchi J, Yoshikawa K et al. Effect of a selective neutrophil elastase inhibitor on mortality and ventilator-free days in patients with increased extravascular lung water: a post hoc analysis of the PiCCO Pulmonary Edema Study. J. Intensive Care 2014; 2: 67.
11. Matsuda S, Ishikawa KB, Kuwabara K, Fujimori K, Fushimi K, Hashimoto H. Development and use of the Japanese case-mix system. Eurohealth. 2008; 14: 25–30.
12. Yasunaga H, Hashimoto H, Horiguchi H, Miyata H, Matsuda S. Variation in cancer surgical outcomes associated with physician and nurse staffing: a retrospective observational study using the Japanese Diagnosis Procedure Combination Database. BMC Health Serv. Res. 2012; 12: 129.
13. Hamada T, Yasunaga H, Nakai Y, Isayama H, Horiguchi H, Matsuda S, Fushimi K, Koike K. Continuous regional arterial infusion for acute pancreatitis: a propensity score analysis using a nationwide administrative database. Crit. Care 2013; 17: R214.
14. Chikuda H, Yasunaga H, Takeshita K, Horiguchi H, Kawaguchi H, Ohe K, Fushimi K, Tanaka S. Mortality and morbidity after high-dose methylprednisolone treatment in patients with acute cervical spinal cord injury: a propensity-matched analysis using a nationwide administrative database. Emerg. Med. J. 2014; 31: 201–6.
15. Iwagami M, Yasunaga H, Doi K, Horiguchi H, Fushimi K, Matsubara T, Yahagi N, Noiri E. Postoperative polymyxin B hemoperfusion and mortality in patients with abdominal septic shock: a propensity-matched analysis. Crit. Care Med. 2014; 42: 1187–93.
16. Kurita T, Yasuda S, Oba K, Odani T, Kono M, Otomo K, Fujieda Y, Oku K, Bohgaki T, Amengual O et al. The efficacy of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis. Rheumatology (Oxford) 2015; 54: 39–44.
17. Cole SR, Hernan MA. Adjusted survival curves with inverse probability weights. Comput. Methods Programs Biomed. 2004; 75: 45–9.
18. Guo S, Fraser MW. Propensity Score Analysis: Statistical Methods and Applications, 2nd edn. Thousand Oaks, CA, Sage, 2015.
19. Horita N, Hashimoto S, Miyazawa N, Fujita H, Kojima R, Inoue M, Ueda A, Ishigatsubo Y, Kaneko T. Impact of corticosteroids on mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis. Intern. Med. 2015; 54: 1473–9.
20. Tamakuma S, Ogawa M, Aikawa N, Kubota T, Hirasawa H, Ishizaka A, Taenaka N, Hamada C, Matsuoka S, Abiru T. Relationship between neutrophil elastase and acute lung injury in humans. Pulm. Pharmacol. Ther. 2004; 17: 271–9.
21. Aikawa N, Ishizaka A, Hirasawa H, Shimazaki S, Yamamoto Y, Sugimoto H, Shinozaki M, Taenaka N, Endo S, Ikeda T et al. Reevaluation of the efficacy and safety of the neutrophil elastase inhibitor, sivelestat, for the treatment of acute lung injury associated with systemic inflammatory response syndrome; a phase IV study. Pulm. Pharmacol. Ther. 2011; 24: 549–54.
22. Tsuboko Y, Takeda S, Mii S, Nakazato K, Tanaka K, Uchida E, Sakamoto A. Clinical evaluation of sivelestat for acute lung injury/acute respiratory distress syndrome following surgery for abdominal sepsis. Drug Des. Devel. Ther. 2012; 6: 273–8.
23. Miyoshi S, Hamada H, Ito R, Katayama H, Irifune K, Suwaki T, Nakanishi N, Kanematsu T, Dote K, Aibiki M et al. Usefulness of a selective neutrophil elastase inhibitor, sivelestat, in acute lung injury patients with sepsis. Drug Des. Devel. Ther. 2013; 7: 305–16.
24. Tsushima K, Yokoyama T, Matsumura T, Koizumi T, Kubo K, Tatsumi K. The potential efficacy of noninvasive ventilation with administration of a neutrophil elastase inhibitor for acute respiratory distress syndrome. J. Crit. Care 2014; 29: 420–5.
25. Aikawa N, Kawasaki Y. Clinical utility of the neutrophil elastase inhibitor sivelestat for the treatment of acute respiratory distress syndrome. Ther. Clin. Risk Manag. 2014; 10: 621–9.
26. Kikuchi T, Kugimiya T, Katashima S. Usefulness of sivelestat sodium administration in patients with aspiration pneumonia. J. Anesth. 2006; 20: 355.
27. Shime N, Hashimoto S. Sivelestat sodium for aspiration-related acute lung injury: a review and analysis of published case reports. Masui 2006; 55: 735–41.
28. Hayashida K, Fujishima S, Sasao K, Orita T, Toyoda Y, Kitano M, Hori S. Early administration of sivelestat, the neutrophil elastase inhibitor, in adults for acute lung injury following gastric aspiration. Shock 2011; 36: 223–7.
29. Agarwal R, Nath A, Aggarwal AN, Gupta D. Do glucocorticoids decrease mortality in acute respiratory distress syndrome? A meta-analysis. Respirology 2007; 12: 585–90.
30. Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, Fan E, Camporota L, Slutsky AS. Acute respiratory distress syndrome: the Berlin definition. JAMA 2012; 307: 2526–33.