Reevaluation of the efficacy and safety of the neutrophil elastase inhibitor, Sivelestat, for the treatment of acute lung injury associated with systemic inflammatory response syndrome; a phase IV study

Pulmonary Pharmacology and Therapeutics

Volumn 24, Issue 5, 2011, Pages 549-554

  Aikawa, Naoki ^a   Ishizaka, Akitoshi ^a   Hirasawa, Hiroyuki ^b   Shimazaki, Shuji ^c   Yamamoto, Yasuhiro ^d   Sugimoto, Hisashi ^e   Shinozaki, Masahiro ^f   Taenaka, Nobuyuki ^g   Endo, Shigeatsu ^h   Ikeda, Toshiaki ⁱ   Kawasaki, Yasushi ^j  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d NIPPON MEDICAL SCHOOL   (Japan)

^e OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^g TAKARAZUKA CITY HOSPITAL   (Japan)

^h IWATE MEDICAL UNIVERSITY   (Japan)

ⁱ TOKYO MEDICAL UNIVERSITY HACHIOJI MEDICAL CENTER   (Japan)

^j ONO PHARMACEUTICAL CO   (Japan)

more..

Author keywords

Anoxia; ARDS; IPTW; Mortality; STRIVE study; VFD

Indexed keywords

SIVELESTAT;

ACUTE LUNG INJURY; ADULT; AGED; ARTICLE; ARTIFICIAL VENTILATION; BENIGN TUMOR; BLOOD DISEASE; CLINICAL ASSESSMENT; CLINICAL EVALUATION; CONTINUOUS INFUSION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MARKER; DRUG EFFICACY; DRUG INTOXICATION; DRUG SAFETY; DRUG TOLERABILITY; ENDOCRINE DISEASE; FEMALE; GASTROINTESTINAL DISEASE; HEART DISEASE; HEPATOBILIARY DISEASE; HOSPITAL DISCHARGE; HUMAN; INFECTION; INFESTATION; INJURY; INTENSIVE CARE UNIT; JAPAN; JAPANESE; KIDNEY DISEASE; LYMPHATIC SYSTEM DISEASE; MAJOR CLINICAL STUDY; MALE; MEDIASTINUM DISEASE; MULTICENTER STUDY; NEOPLASM; NEUROLOGIC DISEASE; OUTCOME ASSESSMENT; PHASE 4 CLINICAL TRIAL; PRIORITY JOURNAL; PROGNOSIS; RESPIRATORY TRACT DISEASE; SURVIVAL RATE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THORAX DISEASE; TREATMENT DURATION; TREATMENT OUTCOME; URINARY TRACT DISEASE; VASCULAR DISEASE; VENTILATOR;

ACUTE LUNG INJURY; AGED; AGED, 80 AND OVER; FEMALE; GLYCINE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; PROTEINASE INHIBITORY PROTEINS, SECRETORY; RESPIRATION, ARTIFICIAL; SERINE PROTEINASE INHIBITORS; SULFONAMIDES; SURVIVAL RATE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; VENTILATOR WEANING;

EID: 80052417467     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2011.03.001     Document Type: Article

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